Dr. Brendon M. Stiles

Dr. Brendon M. Stiles, MD, is a nationally recognized expert in thoracic surgical oncology and serves as Professor and Chief of Thoracic Surgery, as well as Associate Director for Surgical Services at Montefiore Einstein Cancer Center. He earned his MD from the University of Virginia School of Medicine and completed his general surgery training and residency there. He pursued fellowship training in surgical oncology at Memorial Sloan Kettering Cancer Center, followed by cardiothoracic surgery training at NewYork-Presbyterian/Weill Cornell. A native of San Francisco and board-certified in Thoracic Surgery, Dr. Stiles practices at Montefiore’s Moses Campus and affiliated locations across the Bronx. He offers both in-person and telehealth consultations for lung, esophageal, and complex thoracic cancers, emphasizing minimally invasive, organ-sparing procedures tailored to each patient’s needs.

He is widely recognized for his clinical and translational research efforts in thoracic oncology. His studies focus on early-stage and screen-detected lung cancer, neoadjuvant immunotherapy, and the tumor microenvironment. In the lab, he investigates ART1-mediated immune resistance mechanisms and has developed a potential therapeutic antibody targeting ART1 to enhance T-cell response against tumor cells. He has authored multiple manuscripts and guidelines on lung cancer management, esophageal cancer, and multimodal treatment models. Dr. Stiles has also shared his insights through invited talks at national and international oncology conferences.

He is deeply involved in leadership, mentorship, and advocacy within the lung cancer community. Since 2017, he has chaired the Lung Cancer Research Foundation and holds roles in the National Lung Cancer Roundtable and Lung-RADS Steering Committee. He is an active member of professional societies—including AATS, STS, ASCO, ESTS, and IASLC—and contributes to lung cancer screening standards. Through his combination of patient-centered surgical care, bench-to-bedside research, and leadership in education and advocacy, Dr. Stiles is considered a top expert in thoracic surgical oncology.