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Dr. Elizabeth Plimack

Medical Oncologist, Hematologist Oncologist · Urologic Cancers
AddressFox Chase Cancer Center, 333 Cottman Avenue, Philadelphia PA 19111

Dr. Elizabeth R. Plimack, MD, MS, is a globally recognized medical oncologist and clinical trialist specializing in genitourinary malignancies, with a focus on bladder and kidney cancers. She serves as Deputy Director of the Fox Chase Cancer Center, where she also holds the position of Chief of the Division of Genitourinary Medical Oncology. Dr. Plimack earned her medical degree from New York University School of Medicine and completed her residency in Internal Medicine at the New York-Presbyterian Hospital/Weill Cornell Medical Center. She pursued fellowship training in Hematology and Medical Oncology at the University of Chicago and holds a Master of Science in Clinical Epidemiology from the University of Pennsylvania. She is board-certified in Internal Medicine and Medical Oncology.

A trailblazer in the development of immunotherapy and targeted therapy approaches for urothelial carcinoma, Dr. Plimack has led pivotal clinical trials that have reshaped the treatment landscape for bladder cancer. Her research focuses on integrating biomarker-driven strategies into clinical practice, advancing neoadjuvant and adjuvant immunotherapy, and developing rational combinations to overcome therapeutic resistance. Dr. Plimack has authored over 150 peer-reviewed publications and serves as a national principal investigator for multiple NCI-sponsored trials.

In addition to her clinical research leadership, Dr. Plimack is a dedicated mentor and educator, guiding the careers of young oncologists and fostering collaborative research efforts within the GU oncology community. She plays an active role in national guideline development and serves on steering committees for major cooperative groups and industry-sponsored trials. Dr. Plimack’s contributions continue to drive innovation in genitourinary oncology, improving outcomes and expanding treatment options for patients with bladder and kidney cancers.

Education

Medical School:

New York University School of Medicine

Residency:

Internal Medicine, New York University Medical Center

Fellowship:

Medical Oncology, MD Anderson Cancer Center

Board Certification:

American Board of Internal Medicine, American Board of Medical Oncology

Awards
  • National Cancer Institute Cancer Clinical Investigator Team Leadership Award - 2015
  • ASCO-American Cancer Society Cancer Prevention Award - 2025
  • Named Top Doctor by Philadelphia Magazine - 2017
Memberships and affiliations
  • American Society of Clinical Oncology
  • American Society for Clinical Investigation
  • Association of American Physicians
  • Elected Board Member of ASCO 2020-2024
  • Treasurer ASCO 2023-2024
  • Fox Chase Cancer Center
  • Penn Medicine network
Research and publications
  • Genomic alterations in the DNA repair-associated genes ATM, RB1, and FANCC predict response and clinical benefit after cisplatin-based chemotherapy for muscle-invasive bladder cancer
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