Dr. Frank Cackowski

Dr. Frank Cackowski, MD, PhD, is a physician-scientist and medical oncologist specializing in genitourinary cancers, with a particular focus on prostate cancer and tumor biology. He serves as an Assistant Professor of Medicine at the University of Michigan Rogel Cancer Center. Dr. Cackowski earned his medical degree and PhD in Cancer Biology from the University of Michigan, where he also completed his internal medicine residency and hematology/oncology fellowship. He is board-certified in Internal Medicine and Medical Oncology.

Dr. Cackowski’s research investigates the bone microenvironment in metastatic prostate cancer, aiming to understand how tumor cells interact with bone to promote metastasis and treatment resistance. His laboratory work explores novel therapeutic targets in bone-tumor signaling pathways and the development of preclinical models to test new drugs. He has been involved in clinical and translational studies to move promising laboratory findings into early-phase clinical trials for patients with advanced prostate cancer.

In addition to his scientific contributions, Dr. Cackowski is committed to training the next generation of cancer researchers. He mentors graduate students, medical trainees, and fellows, fostering interest in translational oncology. His work has been recognized with multiple early-career investigator awards, and he continues to publish in high-impact scientific journals. Through his dual focus on discovery science and clinical translation, Dr. Frank Cackowski is advancing the understanding and treatment of metastatic prostate cancer.