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Dr. James D. Griffin

Surgical Oncologist · Gastrointestinal Cancers
Address450 Brookline Avenue Boston MA 02215

Dr. James D. Griffin, MD, is a renowned hematologist-oncologist and physician-scientist whose career has been dedicated to advancing the molecular understanding and treatment of leukemia. He serves as Professor of Medicine at Harvard Medical School and Director of the Medical Oncology Division at Dana-Farber Cancer Institute. Dr. Griffin earned his medical degree from Harvard Medical School, completed his internal medicine residency at Massachusetts General Hospital, and trained as a medical oncology fellow at Dana-Farber Cancer Institute. He is board-certified in Internal Medicine and Medical Oncology.

Dr. Griffin’s groundbreaking research focuses on the role of tyrosine kinases, including FLT3 and KIT, in the pathogenesis of acute myeloid leukemia (AML) and other hematologic malignancies. His work has been central to the development and clinical adoption of targeted kinase inhibitors, which have transformed the treatment landscape for these diseases. He has authored over 300 peer-reviewed publications and has played a pivotal role in translating laboratory discoveries into effective clinical therapies.

As a leader in academic oncology, Dr. Griffin has mentored generations of clinician-scientists, many of whom now direct leukemia research programs worldwide. He serves on national and international advisory committees, contributes to NIH review panels, and is active in cooperative group research initiatives. Through his dual commitment to scientific discovery and patient care, Dr. James D. Griffin continues to influence the direction of leukemia research and treatment strategies globally.

Education

Medical School:

Harvard Medical School

Residency:

Internal Medicine, Johns Hopkins Hospital

Fellowship:

Hematology, Massachusetts General Hospital, Medical Oncology Fellowship Dana-Farber Cancer Institute

Board Certification:

American Board of Internal Medicine, American Board of Medical Oncology

Awards
  • Dr Anthony Cortese Award 2001
  • Johns Hopkins University Society of Scholars 2003
Memberships and affiliations
  • Scientific Advisory Boards of Georgetown Lombardi Cancer Center
  • Scientific Advisory Board Johns Hopkins Cancer Center
  • DF/HCC Leukemia Program
  • Professor
  • Dana-Farber Cancer Institute
  • Brigham and Women’s Hospital
Research and publications
  • Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation
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