Dr. James J. Harding

Medical Oncologist, specializing in Gastrointestinal Cancers

160 East 53rd Street New York NY 10022
646-888-4314

Dr. James J. Harding, MD, is a distinguished medical oncologist specializing in the treatment of gastrointestinal cancers, with a particular focus on liver, bile duct, pancreas, and colorectal malignancies. He serves as a medical oncologist at Memorial Sloan Kettering Cancer Center and holds dual appointments in the Early Drug Development Service and the Gastrointestinal Oncology Service. Dr. Harding earned his medical degree from Thomas Jefferson University’s Sidney Kimmel Medical College, followed by residency training in internal medicine at NewYork-Presbyterian Hospital/Weill Cornell Medical Center. He completed his oncology fellowship at MSKCC, where he has since built a career at the intersection of precision medicine and clinical innovation.

Dr. Harding is recognized for his leadership in early-phase clinical trials and translational research targeting genetic and molecular alterations in GI cancers. He has played a pivotal role in developing novel therapeutics, particularly for patients with rare or treatment-resistant tumors. His work has contributed to a deeper understanding of biomarker-driven therapies, especially in hepatocellular carcinoma and biliary tract cancers, where options have traditionally been limited. Dr. Harding has authored numerous peer-reviewed publications and presented at major oncology conferences, helping shape evolving standards in gastrointestinal cancer care.

A committed educator and clinical investigator, Dr. Harding mentors fellows and residents while actively collaborating with multidisciplinary teams to deliver individualized treatment plans. He is board-certified in medical oncology and internal medicine and is a member of professional organizations including the American Society of Clinical Oncology and the American Association for Cancer Research. Through his dedication to advancing therapeutic strategies and his compassionate approach to patient care, Dr. Harding stands at the forefront of innovation in gastrointestinal oncology and early drug development.

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