Dr. Julie E. Lang
Breast Surgical Oncologist · Breast CancerDr. Julie E. Lang, MD, is a widely respected breast surgical oncologist and physician-scientist currently serving as Chief of Breast Surgery and co-leader of the Breast Cancer Program at Cleveland Clinic. She earned her MD from the University of North Carolina at Chapel Hill and completed her general surgery residency and postdoctoral research fellowship at UCSF before undertaking specialized fellowship training in breast surgical oncology at MD Anderson Cancer Center. Board-certified in general surgery, Dr. Lang is known for her expertise in advanced procedures—including nipple-sparing mastectomy, oncoplastic reconstruction, and management of aggressive breast cancers—and for her compassionate, patient-focused approach.
A leader in translational breast cancer research, Dr. Lang’s work emphasizes liquid biopsy technologies such as circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA), examining their roles in early diagnosis and treatment monitoring. She is a key investigator in landmark multicenter trials, including I-SPY2 and studies assessing KEYNOTE-522 in triple-negative breast cancer, and her lab has engineered clinically relevant patient-derived xenograft models for inflammatory breast carcinoma. With nearly 200 peer-reviewed publications, her scholarship has driven precision medicine forward and shaped biomarker-driven treatment strategies that enhance patient outcomes.
In her role as educator and mentor, Dr. Lang trains surgical fellows, medical residents, and junior scientists, while maintaining leadership positions within professional organizations such as ASCO, AACR, and the American College of Surgeons. Her excellence has been recognized with multiple “Top Doctor” awards and honors like the Donald L. Morton Award. Patients consistently praise her clear communication, empathy, and expert surgical skill. Bridging cutting-edge clinical care, groundbreaking research, and compassionate mentorship, Dr. Lang continues to advance the field of breast surgical oncology.
Education
Medical School:
University of North Carolina at Chapel Hill School of Medicine
Residency:
General Surgery, UCSF Department of Surgery
Fellowship:
Breast Surgical Oncology, MD Anderson Cancer Center
Board Certification:
Surgery
Awards
- Donald L. Morton Award, Journal of Surgical Oncology 2015
- Southern California Clinical Translational Research Institute KL2 Institutional Scholar 2013-2014
- Pasadena Magazine Top Doctor, Breast Oncology 2013
- Fellow of the American College of Surgeons
- Louis J. Kettel Faculty Mentor Award (Clinical Sciences)
- American Society of Clinical Oncology Foundation Merit Award
- Chief Resident Research Award, University of California, San Francisco
Memberships and affiliations
- Cleveland Clinic Cancer Center
- American Society of Breast Surgeons
- Society of Surgical Oncology
- American Society of Clinical Oncology
- American College of Surgeons
Research and publications
- Bone-Induced HER2 Promotes Secondary Metastasis in HR+/HER2- Breast Cancer.
- ASO Author Reflections: Real-World Results of the KEYNOTE-522 Regimen to Guide Surgical Decision Making.
- Real-World Outcomes with the KEYNOTE-522 Regimen in Early-Stage Triple-Negative Breast Cancer.
- Precision Oncology in Breast Cancer Surgery.
- Adjuvant Trastuzumab Emtansine Versus Paclitaxel and Trastuzumab in Stage I HER2-Positive Breast Cancer: The ATEMPT Trial.
- Neoadjuvant Trebananib plus Paclitaxel-based Chemotherapy for Stage II/III Breast Cancer in the Adaptively Randomized I-SPY2 Trial-Efficacy and Biomarker Discovery.
- Integrated Proteogenomic Analysis Reveals Distinct Potentially Actionable Therapeutic Vulnerabilities in Triple-Negative Breast Cancer Subtypes.
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