Novel Biochemical and Molecular Determinants for Soft Tissue Sarcoma
Summary
The purpose of this study is to study normal and sarcoma cells. To study these cells we need to have human tissue. You will be having or have already had a procedure to remove tissue. We would like to use some of this tissue. We will use it for laboratory studies on the diagnosis,behavior and treatment of sarcoma. We will perform an extensive analysis of your samples. We will only use extra tissue left over after all needed testing has been done or remove an additional small amount of tissue if you are having a biopsy. We will also take blood samples before and/or after your procedure to measure biochemical factors that may help us predict the behavior of sarcoma.
Detailed description
In this protocol, we plan to identify specific markers from biochemical, proteomic, epigenetic and molecular genetic analyses that predict clinical outcome, responsiveness to therapy and might serve as promising therapeutic targets in patients with soft tissue sarcoma.
Arms & interventions
- OtherSpecimen protocol
The research specimen will be obtained from the residual specimen that would otherwise be discarded per usual hospital procedure.
Outcome measures
Primary
establish and maintain a specimen bank and sarcoma cell line resource
for laboratory-based studies on the causes, prevention, diagnosis and treatment of human soft tissue sarcoma
Time frame: 2 years
Secondary
identify new rational therapeutic targets
Time frame: 2 years
Eligibility criteria
Study locations (7)
Memorial Sloan Kettering Basking Ridge (Consent and Follow-Up)
Basking Ridge, New Jersey, 07920
Memorial Sloan Kettering Monmouth (Consent and Followup)
Middletown, New Jersey, 07748
Memorial Sloan Kettering Bergen (Consent and Follow up)
Montvale, New Jersey, 07645
Memorial Sloan Kettering Commack (Consent and Follow-Up)
Commack, New York, 11725
Memorial Sloan Kettering Westchester (Consent and Followup)
Harrison, New York, 10604
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, 10065
Memorial Sloan Kettering Nassau (Consent and Followup)
Rockville Centre, New York, 11553