Multi-Institution Registry of SRS/SBRT Procedures
Summary
The RSSearch® Registry is an international multi-year database designed to track SRS/SBRT (Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy) utilization, treatment practices and outcomes to help determine, over time, the most effective use of these systems in management of patients with life threatening tumors and other diseases. (This study was formally called ReCKord and included the CyberKnife only; The ReCKord study continues as a CyberKnife subset of RSSearch.)
Detailed description
The Registry is designed to help SRS/SBRT (Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy) users to understand utilization of and key treatment outcomes for these treatment approaches. Some of the objectives include: Allow participants to record information about usage of SRS/SBRT in everyday practice, including patient characteristics and disease information, treatment plans and outcomes Provide participants with ready access to data for publication of their own experience and as a tool for establishing collaborations with other participating sites Facilitate quality improvement efforts for individual treatment providers Understand the effectiveness of different treatment plans for different types of lesions, diseases and treatments The Registry tracks select outcomes for each condition treated by SRS/SBRT (for example, PSA for prostate cancer); the Registry also provides individual participants the ability to add additional outcomes for each and any condition of specific interest to their institutions. The Registry is hosted by Vision Tree, Inc who is an independent vendor of electronic registries; they are responsible for HIPAA compliance, including all security mechanisms. Patients will be enrolled prospectively. Some retrospective patient data is likely to be included in order to capture both short and longer term outcomes data.
Arms & interventions
- RadiationSRS/SBRT
Intervention varies by condition being treated.
Outcome measures
Primary
Overall survival
Survival from time of treatment to death
Time frame: Up to 5 years
Secondary
Local and distant recurrence
Time frame: One to Five years
Eligibility criteria
Study locations (13)
Penrose Cancer Center
Colorado Springs, Colorado, 80907
Sylvester Comprehensive Cancer Center, University of Miami
Miami, Florida, 33146
Southeast Georgia Health System
Brunswick, Georgia, 31520
Henry Ford Health System
Detroit, Michigan, 48202
AtlantiCare Regional Medical Center and AtlantiCare Cancer Care Institute
Egg Harbor, New Jersey, 08234
Riverview Medical Center
Red Bank, New Jersey, 07701
NJ Cyberknife at Community Medical Center
Toms River, New Jersey, 08755
Montefiore Medical Center
The Bronx, New York, 10502
Geisinger Health System
Danville, Pennsylvania, 17822
Philadelphia CyberKnife
Philadelphia, Pennsylvania, 19083
Pottstown Memorial Medical Center
Pottstown, Pennsylvania, 19464
Cyberknife at Erlanger
Chattanooga, Tennessee, 37403
St. Mary's Medical Center
Huntington, West Virginia, 25701
References
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- Davis JN, Medbery C, Sharma S, Pablo J, Kimsey F, Perry D, Muacevic A, Mahadevan A. Stereotactic body radiotherapy for centrally located early-stage non-small cell lung cancer or lung metastases from the RSSearch((R)) patient registry. Radiat Oncol. 2015 May 15;10:113. doi: 10.1186/s13014-015-0417-5.(PubMed)
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- Ricco A, Davis J, Rate W, Yang J, Perry D, Pablo J, D'Ambrosio D, Sharma S, Sundararaman S, Kolker J, Creach KM, Lanciano R. Lung metastases treated with stereotactic body radiotherapy: the RSSearch(R) patient Registry's experience. Radiat Oncol. 2017 Feb 1;12(1):35. doi: 10.1186/s13014-017-0773-4.(PubMed)
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- Singh R, Davis J, Sharma S. Stereotactic Radiosurgery for Trigeminal Neuralgia: A Retrospective Multi-Institutional Examination of Treatment Outcomes. Cureus. 2016 Apr 3;8(4):e554. doi: 10.7759/cureus.554.(PubMed)
- Mahadevan A, Blanck O, Lanciano R, Peddada A, Sundararaman S, D'Ambrosio D, Sharma S, Perry D, Kolker J, Davis J. Stereotactic Body Radiotherapy (SBRT) for liver metastasis - clinical outcomes from the international multi-institutional RSSearch(R) Patient Registry. Radiat Oncol. 2018 Feb 13;13(1):26. doi: 10.1186/s13014-018-0969-2.(PubMed)