Intra- and Inter-fraction Changes in Radiation Therapy
Summary
Analysis to quantify intra-fraction, inter-fraction and post-treatment changes in tumor target volumes and surrounding normal organs in radiation therapy.
Detailed description
The accurate and detailed knowledge of the changes (e.g., anatomically/biologically intra- and inter-fraction changes) to be obtained from this study would allow the research team to determine how Adaptive Radiation Therapy (ART) should be performed for a given tumor site/type. Radiation oncologists then can choose a proper ART strategy for a given tumor type to account for the anatomic/biological intra- and inter-fraction changes, improving accuracy of radiation therapy delivery, and in turn reducing treatment related toxicities and/or improving tumor local control.
Arms & interventions
- RadiationRadiation Therapy
Radiation therapy plans for cancer patients who have completed treatment.
Outcome measures
Primary
Changes of volumes from baseline of organs at risk during and after radiation therapy.
Changes of organs at risk volumes (cm\^3) during and after radiation therapy.
Time frame: 2 years
Secondary
Changes of volumes from baseline or tumors during and after radiation therapy.
Time frame: 2 years
Eligibility criteria
Study locations (1)
Froedtert Hospital
Milwaukee, Wisconsin, 53226