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Helping Men Adhere to Sexual Rehabilitation Following Prostate Cancer Surgery
NCT ID: NCT02706561Sponsor: Memorial Sloan Kettering Cancer CenterLast updated: 2026-04-08
Summary
The purpose of this study is to test two different ways to help men with sexual rehabilitation.
Arms & interventions
- Behavioralquestionnaires
- Behavioralthree in-person sessions
- Behavioralmonthly phone calls
- BehavioralAcceptance and Commitment Therapy for Erectile Dysfunction (ACT-ED)
- BehavioralEnhanced Monitoring and Education (EME)
Outcome measures
Primary
percentages of patients having an Erectile Function Domain (EFD) total score >= 24
The EFD score of \>= 24 will be used to indicate "good" erectile function. This is both a face valid cut-off, and a cut off that is commonly used in the literature as "good" erectile function following radical prostatectomy.
Time frame: 1 year
Eligibility criteria
Sex: MaleAge: 21 Years and olderHealthy volunteers: No
Inclusion Criteria:
* As per medical record, early stage prostate cancer (Pathologic Stage 1/2 with Gleason score \</=8; or Pathologic Stage 3 with Gleason score =/\< 7)
* As per medical record, radical prostatectomy (RP) conducted either at MSKCC or at another institution
* As per medical record, ≤ 9 months post-RP
* As per medical record, moderate erectile functioning pre-surgery (i.e., 15 or greater on the IIEF Erectile Function Domain (EFD) score, or graded their erections as a 1 or 2 on the standard 5 point Urology Erectile Function scale, or have a score of 6 or greater on the 1-10 pre-surgery erectile function scale on the SMRP assessment or have a total score of 15 or greater on items 2-7 on the Prostrate Quality of Life Survey: Sexual Domain)
* As per self report or as per medical record starting penile injections as part of the erectile rehabilitation program at MSKCC
* In the judgment of the consenting professional able to communicate, comprehend, and complete questionnaires in English
Exclusion Criteria:
* Both cavernous nerves fully resected as per surgery report (nerve sparing score of 8 in MSKCC surgeon note), or documented in the progress note that the nerves were fully resected.
* Currently on or has a history of being an Androgen Deprivation Therapy (ADT)
* Has any indication of Prostate-Specific Antigen (PSA)
* As per self report, specific injection phobia
* In the judgment of the consenting professional is unable to provide informed consent and complete study sessions and assessment.
* As per self report or as documented in the medical record, current untreated (e.g. no medication no therapy) major psychiatric disorder (schizophrenia, major depression). Patients diagnosed with a major psychiatric disorder will be reviewed by the study PI to determine eligibility prior to consent.
Study locations (1)
Memorial Sloan Kettering Cancer Center
New York, New York, 10065