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RecruitingInterventional

Photoacoustic Imaging of Human Breast

NCT ID: NCT03897270Sponsor: Roswell Park Cancer InstituteLast updated: 2026-04-07

Summary

This trial studies photoacoustic imaging of the breast in patients with breast cancer and healthy subjects. Dense breasts typically reduce the sensitivity of a mammography and also is associated with a higher risk of breast cancer. Photoacoustic tomography combines light and sound to provide more information about breast tissue.

Detailed description

PRIMARY OBJECTIVES: I. To identify photoacoustic features of breast malignancy and treatment response OUTLINE: Participants undergo photoacoustic imaging of the breast over 30 minutes. At subject's discretion, imaging may repeat for a total of 10 studies, each in a separate day.

Arms & interventions

  • ProcedurePhotoacoustic Imaging

    Undergo photoacoustic imaging of the breast

Outcome measures

Primary

  • Identify photoacoustic features of breast malignancies

    Photoacoustic excitation and detection will be performed

    Time frame: Up to 3 years

Eligibility criteria

Sex: FemaleAge: 18 Years and olderHealthy volunteers: Yes
Inclusion Criteria: * Women with clinically suspicious or confirmed breast cancer masses (that have not been surgically removed) and will/have already undergo/undergone breast magnetic resonance imaging (MRI). Exclusion Criteria: * Pregnant women (there are no known risks to these procedures, but any unforeseen risks are as yet undetermined, so pregnant women will be excluded by means of a verbal confirmation at time of screening). * Women who have had breast implants in the previous 6 months. * Women who have had lumpectomy * Adults unable to consent. * Individuals who are not yet adults (infants, children, teenagers). * Pregnant women. * Prisoners. * There is no direct benefit of the study to any subject either non-English or English speaker. To facilitate the consent process, we will exclude non-English speaking subjects.

Study locations (1)

Roswell Park Cancer Institute

Buffalo, New York, 14263

Recruiting
Ermelinda Bonaccio · Contact
Ermelinda Bonaccio · Principal Investigator
Photoacoustic Imaging of the Breast in Patients With Breast Cancer and Healthy Subjects | Cancerify