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RecruitingInterventionalPhase 3

Randomized Phase III Trial Incorporating Apalutamide and Advanced Imaging Into Salvage Treatment for Patients With Node-Positive Prostate Cancer After Radical Prostatectomy (INNOVATE*) *INtensifying Treatment for NOde Positive Prostate Cancer by VArying the Hormonal ThErapy

NCT ID: NCT04134260Sponsor: NRG OncologyLast updated: 2026-05-07

Summary

This phase III trial studies whether adding apalutamide to the usual treatment improves outcome in patients with lymph node positive prostate cancer after surgery. Radiation therapy uses high energy x-ray to kill tumor cells and shrink tumors. Androgens, or male sex hormones, can cause the growth of prostate cancer cells. Drugs, such as apalutamide, may help stop or reduce the growth of prostate cancer cell growth by blocking the attachment of androgen to its receptors on cancer cells, a mechanism similar to stopping the entrance of a key into its lock. Adding apalutamide to the usual hormone therapy and radiation therapy after surgery may stabilize prostate cancer and prevent it from spreading and extend time without disease spreading compared to the usual approach.

Detailed description

PRIMARY OBJECTIVE: I. Compare metastasis-free survival (MFS) of salvage radiation therapy (RT) and gonadotropin releasing hormone (GnRH) agonist/antagonist versus (vs.) RT/GnRH agonist/antagonist with apalutamide for patients with pathologic node-positive prostate cancer after radical prostatectomy with detectable prostate-specific antigen (PSA). SECONDARY OBJECTIVES: I. Compare health-related quality of life (Expanded Prostate Cancer Index Composite \[EPIC\]-26, EuroQol \[EQ\]-5 Dimension \[D\]-5 Level \[L\], Brief Pain Inventory, Patient Reported Outcome Measurement Information System \[PROMIS\]-Fatigue) among the treatment arms. II. Compare overall survival, biochemical progression-free survival, time to local-regional progression, time to castrate resistance, and cancer-specific survival among the treatment arms. III. Compare the short-term and long-term treatment-related adverse events among the treatment arms. EXPLORATORY OBJECTIVES: I. Validate Decipher score for an exclusively node-positive population and use additional genomic information from Affymetrix Human Exon 1.0st array to develop and validate novel prognostic and predictive biomarkers. II. Validate the PAM50-based classification of prostate cancer into luminal A, luminal B, and basal subtypes as prognostic markers and determine whether the luminal B subtype is a predictive marker for having a larger improvement in outcome from the addition of apalutamide. III. To optimize quality assurance methodologies and processes for radiotherapy and imaging with machine learning strategies. OUTLINE: Patients are randomized to 1 of 2 arms. ARM I: Patients receive standard of care hormone therapy per physician discretion for 24 months. Patients also undergo standard of care pelvis and prostate bed radiation therapy 5 days per week over 5-6 or 7-8 weeks beginning within 90 days of randomization in the absence of disease progression or unacceptable toxicity. ARM II: Patients undergo standard of care hormone therapy and radiation therapy as in Arm I. Patients also receive apalutamide orally (PO) once daily (QD) on days 1-90 of each cycle. Cycles repeat every 90 days for 8 cycles in the absence of disease progression or unacceptable toxicity. Patients in both arms may undergo computed tomography (CT), magnetic resonance imaging (MRI), bone scan, and positron emission tomography (PET) as clinically indicated throughout the study. Patients may also undergo blood sample collection throughout the study. After completion of study treatment, patients are followed up every 6 months for 3 years, then annually thereafter.

Arms & interventions

  • DrugApalutamide

    Given PO

  • ProcedureBiospecimen Collection

    Undergo blood sample collection

  • ProcedureBone Scan

    Undergo bone scan

  • ProcedureComputed Tomography

    Undergo CT

  • DrugHormone Therapy

    Receive hormone therapy

  • ProcedureMagnetic Resonance Imaging

    Undergo MRI

  • ProcedurePositron Emission Tomography

    Undergo PET

  • OtherQuality-of-Life Assessment

    Ancillary studies

  • OtherQuestionnaire Administration

    Ancillary studies

  • RadiationRadiation Therapy

    Undergo pelvis and prostate bed radiation therapy

Outcome measures

Primary

  • Metastasis-free survival (MFS)

    Kaplan-Meier curves will be generated and metastasis-free survival compared between the two treatment groups by a logrank test, stratified by prostate specific antigen (PSA) level after prostatectomy (never detectable or rising). Cox regression modeling to assess and adjust for the effects of PSA stratum and other baseline covariates will also be performed. The proportional hazards assumption will be tested using Schoenfeld residuals and graphical methods. Martingale residual plots will be examined to determine the best functional form for incorporating covariates into the model. A competing risks analysis will also be performed with time to distant metastasis or death from prostate cancer as the event of interest and death from other causes as the competing risk. Cumulative incidence curves will be generated along with Fine-Gray's test. Patients alive and metastasis free will be censored as of the time of the last negative examination.

    Time frame: From randomization to detection of metastatic disease or death from any cause, assessed up to 7.5 years

Secondary

  • Quality of life (QOL) between the two treatment arms

    Time frame: Up to 3 years post treatment

  • Overall survival (OS)

    Time frame: From randomization until date of death or censored at last date known alive, assessed up to 7.5 years

  • Biochemical progression-free survival (bPFS)

    Time frame: From randomization until biochemical recurrence or death from prostate cancer, assessed up to 7.5 years

  • Time to local-regional progression

    Time frame: Up to 7.5 years

  • Time to castrate resistance

    Time frame: Up to 7.5 years

  • Cancer-specific survival

    Time frame: Up to 7.5 years

  • Incidence of adverse events

    Time frame: Up to 7.5 years

Eligibility criteria

Sex: MaleAge: 18 Years and olderHealthy volunteers: No
Inclusion Criteria: * Pathologically (histologically) proven diagnosis of prostate adenocarcinoma. Any type of radical prostatectomy is permitted, including retropubic, perineal, laparoscopic or robotically assisted * Any T-stage is eligible (American Joint Committee on Cancer \[AJCC\] 8th edition \[ed\]) * Appropriate stage for study entry based on fluciclovine F-18 PET scan (FACBC, Axumin) F-18 prostate-specific membrane antigen (PSMA) PET (PyLarify) scan, Gallium-68 PSMA PET scan, flotufolastat F-18 PSMA PET scan (Posluma), or C-11 or F-18 Choline PET within 90 days prior to registration that is negative for distant metastatic (M1a, M1b, M1c) disease. For patients with PSA \< 0.20 ng/mL at time of registration, PET scan is recommended but not required * Pathologically node positive disease with nodal involvement only in the pelvis in the prostatectomy specimen or nodal disease on imaging at time of recurrence (including external iliacs, internal iliacs, and/or obturator nodes); peri-prostatic and peri-rectal nodes can also be considered regional lymphadenopathy and are allowed * History/physical examination within 90 days prior to registration * Age \>= 18 * Eastern Cooperative Oncology Group (ECOG) performance status of 0-1 within 90 days prior to registration * Detectable PSA after radical prostatectomy. Detectable PSA is defined as serum PSA \> 0 ng/mL at least 30 days after prostatectomy * Patients who have already started on post-prostatectomy GnRH agonist/antagonist for =\< 180 days prior to registration are eligible (Note: patients who started on an oral antiandrogen are eligible if started =\< 180 days and stopped prior to registration) * Hemoglobin \>= 9.0 g/dL, independent of transfusion and/or growth factors (within 90 days prior to registration) * Platelet count \>= 100,000 x 10\^9/uL independent of transfusion and/or growth factors (within 90 days prior to registration) * Serum potassium \>= 3.5 mmol/L within 90 days prior to registration * Creatinine clearance (CrCl) \>= 30 mL/min estimated by Cockcroft-Gault (please use actual weight for calculation unless greater than 30% above ideal body weight then use the adjusted body weight) (within 90 days prior to registration) * Total bilirubin =\< 1.5 x institutional upper limit of normal (ULN) (Note: In subjects with Gilbert's syndrome, if total bilirubin is \> 1.5 x ULN, measure direct and indirect bilirubin and if direct bilirubin is =\< 1.5 x ULN, subject is eligible) (within 90 days prior to registration) * Aspartate aminotransferase (AST) (serum glutamic oxaloacetic transaminase \[SGOT\]) or alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase \[SGPT\]) =\< 2.5 x institutional ULN (within 90 days prior to registration) * Serum albumin \>= 3.0 g/dL (within 90 days prior to registration) * Discontinue or substitute concomitant medications known to lower the seizure threshold at least 30 days prior to registration * The patient must agree to use a condom (even men with vasectomies) and another effective method of birth control if he is having sex with a woman of childbearing potential or agree to use a condom if he is having sex with a woman who is pregnant while on study drug and for 3 months following the last dose of study drug * Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial and have a CD4 count \>= 200 cells/microliter within 30 days prior to registration. Note: HIV testing is not required for eligibility for this protocol * For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy within 30 days prior to registration, if indicated. Note: HBV viral testing is not required for eligibility for this protocol * Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load within 30 days prior to registration * Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial. Note: Any patient with a cancer (other than keratinocyte carcinoma or carcinoma in situ) who has no evidence of disease for \< 3 years must contact the principal investigator, Ronald Chen, Doctor of Medicine (MD) * The patient or a legally authorized representative must provide study-specific informed consent prior to study entry Exclusion Criteria: * Definitive radiologic evidence of metastatic disease (M1a, M1b or M1c) on molecular imaging (e.g. Fluciclovine F-18 PET, \[FACBC, Axumin\], F-18 PSMA PET \[Pylarify\], flotufolastat F-18 PSMA PET scan \[Posluma\], Gallium-68 PSMA PET scan or C-11 choline PET) * Prior systemic chemotherapy for the study cancer; note that prior chemotherapy for a different cancer is allowed (completed \> 3 years prior to registration) * Prior radiotherapy to the region of the study cancer that would result in overlap of radiation therapy fields * Androgen deprivation therapy (ADT) prior to radical prostatectomy * Prior treatment with androgen receptor signaling inhibitor (including but not exclusive to a growing list of: abiraterone acetate, enzalutamide, apalutamide, darolutamide), unless started =\< 180 days and stopped prior to registration, which is allowed * Current use of 5-alpha reductase inhibitor. NOTE: if the alpha reductase inhibitor is stopped prior to randomization the patient is eligible * History of any of the following: * Seizure or known condition that may pre-dispose to seizure (e.g. prior stroke within 1 year prior to registration, brain arteriovenous malformation, Schwannoma, meningioma, or other benign central nervous system \[CNS\] or meningeal disease which may require treatment with surgery or radiation therapy) * Severe or unstable angina, myocardial infarction, arterial or venous thromboembolic events (e.g., pulmonary embolism, cerebrovascular accident including transient ischemic attacks), or clinically significant ventricular arrhythmias within 12 months prior to registration * New York Heart Association functional classification III/IV (Note: Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association functional classification.) * History of any condition that in the opinion of the investigator, would preclude participation in this study * Current evidence of any of the following: * Known gastrointestinal disorder affecting absorption of oral medications * Active uncontrolled infection * Presence of uncontrolled hypertension (persistent systolic blood pressure \[BP\] \>= 160 mmHg or diastolic BP \>= 100 mmHg). Subjects with a history of hypertension are allowed, provided that BP is controlled to within these limits by anti-hypertensive treatment * Any chronic medical condition requiring a higher dose of corticosteroid than 10 mg prednisone/prednisolone once daily * Baseline moderate and severe hepatic impairment (Child-Pugh Class B \& C) * Inability to swallow oral pills * Any current condition that in the opinion of the investigator, would preclude participation in this study * Patients must not plan to participate in any other therapeutic clinical trials while receiving treatment on this study * Patients with inflammatory bowel disease

Study locations (345)

Cancer Center at Saint Joseph's

Phoenix, Arizona, 85004

Recruiting
Site Public Contact · Contact
720-874-1881ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72205

Recruiting
Site Public Contact · Contact
501-686-8274
Sanjay Maraboyina · Principal Investigator

Kaiser Permanente-Anaheim

Anaheim, California, 92806

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Helen H. Moon · Principal Investigator

Kaiser Permanente-Baldwin Park

Baldwin Park, California, 91706

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Helen H. Moon · Principal Investigator

Kaiser Permanente-Bellflower

Bellflower, California, 90706

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Helen H. Moon · Principal Investigator

Mercy Cancer Center - Carmichael

Carmichael, California, 95608

Recruiting
Site Public Contact · Contact
720-874-1881ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Mercy San Juan Medical Center

Carmichael, California, 95608

Recruiting
Site Public Contact · Contact
916-556-3301OncologyResearch@DignityHealth.org
Shahzad Siddique · Principal Investigator

Mercy Cancer Center - Elk Grove

Elk Grove, California, 95758

Recruiting
Site Public Contact · Contact
720-874-1881ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Kaiser Permanente-Fontana

Fontana, California, 92335

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Helen H. Moon · Principal Investigator

Marin General Hospital

Greenbrae, California, 94904

Recruiting
Site Public Contact · Contact
415-925-7325
Lloyd T. Miyawaki · Principal Investigator

Kaiser Permanente South Bay

Harbor City, California, 90710

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Helen H. Moon · Principal Investigator

Kaiser Permanente-Irvine

Irvine, California, 92618

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Helen H. Moon · Principal Investigator

Tibor Rubin VA Medical Center

Long Beach, California, 90822

Recruiting
Site Public Contact · Contact
562-826-8000
Pankaj Gupta · Principal Investigator

Kaiser Permanente Los Angeles Medical Center

Los Angeles, California, 90027

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Helen H. Moon · Principal Investigator

Los Angeles General Medical Center

Los Angeles, California, 90033

Active Not Recruiting

USC / Norris Comprehensive Cancer Center

Los Angeles, California, 90033

Active Not Recruiting

Kaiser Permanente West Los Angeles

Los Angeles, California, 90034

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Helen H. Moon · Principal Investigator

UCLA / Jonsson Comprehensive Cancer Center

Los Angeles, California, 90095

Recruiting
Site Public Contact · Contact
888-798-0719
Amar Kishan · Principal Investigator

Kaiser Permanente-Ontario

Ontario, California, 91761

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Helen H. Moon · Principal Investigator

Kaiser Permanente - Panorama City

Panorama City, California, 91402

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Helen H. Moon · Principal Investigator

Kaiser Permanente-Riverside

Riverside, California, 92505

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Helen H. Moon · Principal Investigator

Mercy Cancer Center - Rocklin

Rocklin, California, 95765

Recruiting
Site Public Contact · Contact
720-874-1881ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Mercy Cancer Center - Sacramento

Sacramento, California, 95816

Recruiting
Site Public Contact · Contact
720-874-1881ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

University of California Davis Comprehensive Cancer Center

Sacramento, California, 95817

Recruiting
Site Public Contact · Contact
916-734-3089
Richard K. Valicenti · Principal Investigator

Kaiser Permanente-San Diego Zion

San Diego, California, 92120

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Helen H. Moon · Principal Investigator

UCSF Medical Center-Mount Zion

San Francisco, California, 94115

Recruiting
Site Public Contact · Contact
877-827-3222
Steven N. Seyedin · Principal Investigator

UCSF Medical Center-Parnassus

San Francisco, California, 94143

Recruiting
Site Public Contact · Contact
877-827-3222
Steven N. Seyedin · Principal Investigator

UCSF Medical Center-Mission Bay

San Francisco, California, 94158

Recruiting
Site Public Contact · Contact
877-827-3222cancertrials@ucsf.edu
Steven N. Seyedin · Principal Investigator

Kaiser Permanente-San Marcos

San Marcos, California, 92078

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Helen H. Moon · Principal Investigator

Ridley-Tree Cancer Center

Santa Barbara, California, 93105

Active Not Recruiting

Woodland Memorial Hospital

Woodland, California, 95695

Recruiting
Site Public Contact · Contact
720-874-1881ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Kaiser Permanente-Woodland Hills

Woodland Hills, California, 91367

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Helen H. Moon · Principal Investigator

Beebe South Coastal Health Campus

Millville, Delaware, 19967

Recruiting
Site Public Contact · Contact
302-291-6730research@beebehealthcare.org
Gregory A. Masters · Principal Investigator

Helen F Graham Cancer Center

Newark, Delaware, 19713

Recruiting
Site Public Contact · Contact
302-623-4450lbarone@christianacare.org
Gregory A. Masters · Principal Investigator

Medical Oncology Hematology Consultants PA

Newark, Delaware, 19713

Recruiting
Site Public Contact · Contact
302-623-4450lbarone@christianacare.org
Gregory A. Masters · Principal Investigator

Christiana Care Health System-Christiana Hospital

Newark, Delaware, 19718

Recruiting
Site Public Contact · Contact
302-623-4450lbarone@christianacare.org
Gregory A. Masters · Principal Investigator

Beebe Health Campus

Rehoboth Beach, Delaware, 19971

Recruiting
Site Public Contact · Contact
302-291-6730research@beebehealthcare.org
Gregory A. Masters · Principal Investigator

George Washington University Medical Center

Washington D.C., District of Columbia, 20037

Recruiting
Site Public Contact · Contact
202-741-2210
Karan Jatwani · Principal Investigator

UM Sylvester Comprehensive Cancer Center at Aventura

Aventura, Florida, 33180

Recruiting
Site Public Contact · Contact
954-461-2180
Alan Libardi Dal Pra · Principal Investigator

UM Sylvester Comprehensive Cancer Center at Coral Gables

Coral Gables, Florida, 33146

Recruiting
Site Public Contact · Contact
305-243-2647
Alan Libardi Dal Pra · Principal Investigator

UM Sylvester Comprehensive Cancer Center at Deerfield Beach

Deerfield Beach, Florida, 33442

Recruiting
Site Public Contact · Contact
305-243-2647
Alan Libardi Dal Pra · Principal Investigator

UM Sylvester Comprehensive Cancer Center at Doral

Doral, Florida, 33166

Recruiting
Site Public Contact · Contact
kginnity@med.miami.edu
Alan Libardi Dal Pra · Principal Investigator

University of Miami Miller School of Medicine-Sylvester Cancer Center

Miami, Florida, 33136

Recruiting
Site Public Contact · Contact
305-243-2647
Alan Libardi Dal Pra · Principal Investigator

UM Sylvester Comprehensive Cancer Center at Kendall

Miami, Florida, 33176

Recruiting
Site Public Contact · Contact
305-243-2647
Alan Libardi Dal Pra · Principal Investigator

UM Sylvester Comprehensive Cancer Center at Plantation

Plantation, Florida, 33324

Recruiting
Site Public Contact · Contact
305-243-2647
Alan Libardi Dal Pra · Principal Investigator

Tampa General Hospital

Tampa, Florida, 33606

Recruiting
Site Public Contact · Contact
813-844-7829syapchanyk@tgh.org
Rod J. Ellis · Principal Investigator

Grady Health System

Atlanta, Georgia, 30303

Recruiting
Site Public Contact · Contact
404-778-1868
Ashesh B. Jani · Principal Investigator

Emory Proton Therapy Center

Atlanta, Georgia, 30308

Recruiting
Site Public Contact · Contact
404-251-2854allyson.anderson@emory.edu
Ashesh B. Jani · Principal Investigator

Emory University Hospital Midtown

Atlanta, Georgia, 30308

Recruiting
Site Public Contact · Contact
888-946-7447
Ashesh B. Jani · Principal Investigator

Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia, 30322

Recruiting
Site Public Contact · Contact
404-778-1868
Ashesh B. Jani · Principal Investigator

Emory Saint Joseph's Hospital

Atlanta, Georgia, 30342

Recruiting
Site Public Contact · Contact
404-851-7115
Ashesh B. Jani · Principal Investigator

Emory Decatur Hospital

Decatur, Georgia, 30033

Recruiting
Site Public Contact · Contact
440-778-1868clinicaltrialsoncology@dekalbmedical.org
Ashesh B. Jani · Principal Investigator

Emory Johns Creek Hospital

Johns Creek, Georgia, 30097

Recruiting
Site Public Contact · Contact
404-778-5714m.lisa.hwang@emory.edu
Ashesh B. Jani · Principal Investigator

Alton Memorial Hospital

Alton, Illinois, 62002

Recruiting
Site Public Contact · Contact
618-463-7323
Jeff M. Michalski · Principal Investigator

Rush-Copley Medical Center

Aurora, Illinois, 60504

Recruiting
Site Public Contact · Contact
630-978-6212RCMC_Cancer_Research@rush.edu
Sinisa Stanic · Principal Investigator

Advocate Outpatient Center - Aurora

Aurora, Illinois, 60506

Recruiting
Site Public Contact · Contact
ncorp@aah.org
Adam P. Siegel · Principal Investigator

Advocate Good Shepherd Hospital

Barrington, Illinois, 60010

Recruiting
Site Public Contact · Contact
847-842-4847
Adam P. Siegel · Principal Investigator

Illinois CancerCare-Bloomington

Bloomington, Illinois, 61704

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

Illinois CancerCare-Canton

Canton, Illinois, 61520

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

Illinois CancerCare-Carthage

Carthage, Illinois, 62321

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

Northwestern University

Chicago, Illinois, 60611

Recruiting
Site Public Contact · Contact
312-695-1301cancer@northwestern.edu
Sean Sachdev · Principal Investigator

Rush MD Anderson Cancer Center

Chicago, Illinois, 60612

Active Not Recruiting

University of Illinois

Chicago, Illinois, 60612

Recruiting
Site Public Contact · Contact
312-355-3046
Daniel Moreira · Principal Investigator

University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637

Recruiting
Site Public Contact · Contact
773-702-8222cancerclinicaltrials@bsd.uchicago.edu
Mohammad Atiq · Principal Investigator

Advocate Illinois Masonic Medical Center

Chicago, Illinois, 60657

Recruiting
Site Public Contact · Contact
773-296-5360
Adam P. Siegel · Principal Investigator

AMG Crystal Lake - Oncology

Crystal Lake, Illinois, 60014

Recruiting
Site Public Contact · Contact
630-929-6129advocateresearch@advocate.com
Adam P. Siegel · Principal Investigator

Carle at The Riverfront

Danville, Illinois, 61832

Recruiting
Site Public Contact · Contact
800-446-5532Research@Carle.com
Sinisa Stanic · Principal Investigator

Decatur Memorial Hospital

Decatur, Illinois, 62526

Recruiting
Site Public Contact · Contact
217-876-4762morganthaler.jodi@mhsil.com
Bryan A. Faller · Principal Investigator

Northwestern Medicine Cancer Center Kishwaukee

DeKalb, Illinois, 60115

Recruiting
Site Public Contact · Contact
630-352-5360Donald.Smith3@nm.org
Sean Sachdev · Principal Investigator

Illinois CancerCare-Dixon

Dixon, Illinois, 61021

Suspended

Advocate Good Samaritan Hospital

Downers Grove, Illinois, 60515

Recruiting
Site Public Contact · Contact
630-275-1270Barbara.barhamand@advocatehealth.com
Adam P. Siegel · Principal Investigator

Carle Physician Group-Effingham

Effingham, Illinois, 62401

Recruiting
Site Public Contact · Contact
800-446-5532Research@carle.com
Sinisa Stanic · Principal Investigator

Crossroads Cancer Center

Effingham, Illinois, 62401

Recruiting
Site Public Contact · Contact
217-876-4762morganthaler.jodi@mhsil.com
Bryan A. Faller · Principal Investigator

Advocate Sherman Hospital

Elgin, Illinois, 60123

Recruiting
Site Public Contact · Contact
847-429-2907
Adam P. Siegel · Principal Investigator

Elmhurst Memorial Hospital

Elmhurst, Illinois, 60126

Recruiting
Site Public Contact · Contact
630-758-5460Jrohde@emhc.org
Matthew Siegel · Principal Investigator

Illinois CancerCare-Eureka

Eureka, Illinois, 61530

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

NorthShore University HealthSystem-Evanston Hospital

Evanston, Illinois, 60201

Recruiting
Site Public Contact · Contact
847-570-2109
Nicklas R. Pfanzelter · Principal Investigator

Illinois CancerCare-Galesburg

Galesburg, Illinois, 61401

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

Western Illinois Cancer Treatment Center

Galesburg, Illinois, 61401

Suspended

Northwestern Medicine Cancer Center Delnor

Geneva, Illinois, 60134

Recruiting
Site Public Contact · Contact
630-352-5360Donald.Smith3@nm.org
Sean Sachdev · Principal Investigator

NorthShore University HealthSystem-Glenbrook Hospital

Glenview, Illinois, 60026

Recruiting
Site Public Contact · Contact
847-570-2109
Nicklas R. Pfanzelter · Principal Investigator

Ingalls Memorial Hospital

Harvey, Illinois, 60426

Recruiting
Site Public Contact · Contact
708-915-4673clinicaltrials@ingalls.org
James A. Wallace · Principal Investigator

Advocate South Suburban Hospital

Hazel Crest, Illinois, 60429

Recruiting
Site Public Contact · Contact
708-799-9995
Adam P. Siegel · Principal Investigator

NorthShore University HealthSystem-Highland Park Hospital

Highland Park, Illinois, 60035

Recruiting
Site Public Contact · Contact
847-570-2109
Nicklas R. Pfanzelter · Principal Investigator

Illinois CancerCare-Kewanee Clinic

Kewanee, Illinois, 61443

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

AMG Libertyville - Oncology

Libertyville, Illinois, 60048

Recruiting
Site Public Contact · Contact
630-929-6129advocateresearch@advocatehealth.com
Adam P. Siegel · Principal Investigator

Condell Memorial Hospital

Libertyville, Illinois, 60048

Recruiting
Site Public Contact · Contact
630-929-6129advocateresearch@advocatehealth.com
Adam P. Siegel · Principal Investigator

Illinois CancerCare-Macomb

Macomb, Illinois, 61455

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

Carle Physician Group-Mattoon/Charleston

Mattoon, Illinois, 61938

Recruiting
Site Public Contact · Contact
800-446-5532Research@carle.com
Sinisa Stanic · Principal Investigator

Loyola University Medical Center

Maywood, Illinois, 60153

Recruiting
Site Public Contact · Contact
708-226-4357
Abhishek A. Solanki · Principal Investigator

Edward Hospital/Cancer Center

Naperville, Illinois, 60540

Recruiting
Site Public Contact · Contact
630-646-6075
Matthew Siegel · Principal Investigator

UC Comprehensive Cancer Center at Silver Cross

New Lenox, Illinois, 60451

Recruiting
Site Public Contact · Contact
773-702-8222cancerclinicaltrials@bsd.uchicago.edu
Mohammad Atiq · Principal Investigator

HSHS Saint Elizabeth's Hospital

O'Fallon, Illinois, 62269

Recruiting
Site Public Contact · Contact
217-876-4762morganthaler.jodi@mhsil.com
Bryan A. Faller · Principal Investigator

Northwestern Medicine Oak Brook

Oak Brook, Illinois, 60523

Recruiting
Site Public Contact · Contact
nctnprogram_rhlccc@northwestern.edu
Sean Sachdev · Principal Investigator

Advocate Christ Medical Center

Oak Lawn, Illinois, 60453-2699

Recruiting
Site Public Contact · Contact
800-323-8622
Adam P. Siegel · Principal Investigator

Northwestern Medicine Orland Park

Orland Park, Illinois, 60462

Recruiting
Site Public Contact · Contact
nctnprogram_rhlccc@northwestern.edu
Sean Sachdev · Principal Investigator

University of Chicago Medicine-Orland Park

Orland Park, Illinois, 60462

Recruiting
Site Public Contact · Contact
773-702-8222cancerclinicaltrials@bsd.uchicago.edu
Mohammad Atiq · Principal Investigator

Illinois CancerCare-Ottawa Clinic

Ottawa, Illinois, 61350

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

Advocate High Tech Medical Park

Palos Heights, Illinois, 60463

Recruiting
Site Public Contact · Contact
ncorp@aah.org
Adam P. Siegel · Principal Investigator

Advocate Lutheran General Hospital

Park Ridge, Illinois, 60068

Recruiting
Site Public Contact · Contact
847-384-3621
Adam P. Siegel · Principal Investigator

Illinois CancerCare-Pekin

Pekin, Illinois, 61554

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

OSF Saint Francis Radiation Oncology at Pekin

Pekin, Illinois, 61554

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

Illinois CancerCare-Peoria

Peoria, Illinois, 61615

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

OSF Saint Francis Radiation Oncology at Peoria Cancer Center

Peoria, Illinois, 61615

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

Methodist Medical Center of Illinois

Peoria, Illinois, 61636

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

OSF Saint Francis Medical Center

Peoria, Illinois, 61637

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

Illinois CancerCare-Peru

Peru, Illinois, 61354

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

Valley Radiation Oncology

Peru, Illinois, 61354

Suspended

Illinois CancerCare-Princeton

Princeton, Illinois, 61356

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

Memorial Hospital East

Shiloh, Illinois, 62269

Recruiting
Site Public Contact · Contact
314-747-9912dschwab@wustl.edu
Jeff M. Michalski · Principal Investigator

Southern Illinois University School of Medicine

Springfield, Illinois, 62702

Recruiting
Site Public Contact · Contact
217-545-7929
Bryan A. Faller · Principal Investigator

Springfield Clinic

Springfield, Illinois, 62702

Recruiting
Site Public Contact · Contact
800-444-7541
Bryan A. Faller · Principal Investigator

Springfield Memorial Hospital

Springfield, Illinois, 62781

Recruiting
Site Public Contact · Contact
217-528-7541pallante.beth@mhsil.com
Bryan A. Faller · Principal Investigator

Carle Cancer Center

Urbana, Illinois, 61801

Recruiting
Site Public Contact · Contact
800-446-5532Research@carle.com
Sinisa Stanic · Principal Investigator

Northwestern Medicine Cancer Center Warrenville

Warrenville, Illinois, 60555

Recruiting
Site Public Contact · Contact
630-352-5360Donald.Smith3@nm.org
Sean Sachdev · Principal Investigator

Illinois CancerCare - Washington

Washington, Illinois, 61571

Recruiting
Site Public Contact · Contact
309-243-3605andersonj@illinoiscancercare.com
Bryan A. Faller · Principal Investigator

Reid Health

Richmond, Indiana, 47374

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Howard M. Gross · Principal Investigator

McFarland Clinic - Ames

Ames, Iowa, 50010

Recruiting
Site Public Contact · Contact
515-239-4734ksoder@mcfarlandclinic.com
Joseph J. Merchant · Principal Investigator

UI Health Care Mission Cancer and Blood - Ankeny Clinic

Ankeny, Iowa, 50023

Recruiting
Site Public Contact · Contact
515-241-3305
Seema Harichand-Herdt · Principal Investigator

Saint Anthony Regional Hospital

Carroll, Iowa, 51401

Recruiting
Site Public Contact · Contact
515-689-7658sbenson@iora.org
Seema Harichand-Herdt · Principal Investigator

Saint Luke's Hospital

Cedar Rapids, Iowa, 52402

Active Not Recruiting

Mercy Hospital

Cedar Rapids, Iowa, 52403

Recruiting
Site Public Contact · Contact
319-365-4673
Deborah W. Wilbur · Principal Investigator

Oncology Associates at Mercy Medical Center

Cedar Rapids, Iowa, 52403

Recruiting
Site Public Contact · Contact
319-363-2690
Deborah W. Wilbur · Principal Investigator

UI Health Care Mission Cancer and Blood - West Des Moines Clinic

Clive, Iowa, 50325

Recruiting
Site Public Contact · Contact
515-241-3305
Seema Harichand-Herdt · Principal Investigator

Iowa Methodist Medical Center

Des Moines, Iowa, 50309

Recruiting
Site Public Contact · Contact
515-241-6727
Seema Harichand-Herdt · Principal Investigator

UI Health Care Mission Cancer and Blood - Des Moines Clinic

Des Moines, Iowa, 50309

Recruiting
Site Public Contact · Contact
515-241-3305
Seema Harichand-Herdt · Principal Investigator

Broadlawns Medical Center

Des Moines, Iowa, 50314

Recruiting
Site Public Contact · Contact
515-282-2200
Seema Harichand-Herdt · Principal Investigator

Mercy Medical Center - Des Moines

Des Moines, Iowa, 50314

Recruiting
Site Public Contact · Contact
515-358-6613cancerresearch@mercydesmoines.org
Richard L. Deming · Principal Investigator

UI Health Care Mission Cancer and Blood - Laurel Clinic

Des Moines, Iowa, 50314

Recruiting
Site Public Contact · Contact
515-241-3305
Seema Harichand-Herdt · Principal Investigator

Iowa Lutheran Hospital

Des Moines, Iowa, 50316

Recruiting
Site Public Contact · Contact
515-241-8704
Seema Harichand-Herdt · Principal Investigator

Methodist West Hospital

West Des Moines, Iowa, 50266-7700

Recruiting
Site Public Contact · Contact
515-343-1000
Seema Harichand-Herdt · Principal Investigator

University of Kansas Cancer Center

Kansas City, Kansas, 66160

Recruiting
Site Public Contact · Contact
913-588-3671KUCC_Navigation@kumc.edu
Xinglei Shen · Principal Investigator

The University of Kansas Cancer Center - Olathe

Olathe, Kansas, 66061

Recruiting
Site Public Contact · Contact
913-588-1569OlatheCCResearch@kumc.edu
Xinglei Shen · Principal Investigator

University of Kansas Cancer Center-Overland Park

Overland Park, Kansas, 66210

Recruiting
Site Public Contact · Contact
913-588-3671KUCC_Navigation@kumc.edu
Xinglei Shen · Principal Investigator

Salina Regional Health Center

Salina, Kansas, 67401

Recruiting
Site Public Contact · Contact
785-452-7038mleepers@srhc.com
Xinglei Shen · Principal Investigator

University of Kansas Health System Saint Francis Campus

Topeka, Kansas, 66606

Recruiting
Site Public Contact · Contact
785-295-8000
Xinglei Shen · Principal Investigator

University of Kansas Hospital-Westwood Cancer Center

Westwood, Kansas, 66205

Recruiting
Site Public Contact · Contact
913-588-3671KUCC_Navigation@kumc.edu
Xinglei Shen · Principal Investigator

LSU Health Baton Rouge-North Clinic

Baton Rouge, Louisiana, 70805

Recruiting
Site Public Contact · Contact
225-765-7659research@ololrmc.com
Marshall P. Stagg · Principal Investigator

Our Lady of the Lake Physician Group

Baton Rouge, Louisiana, 70808

Recruiting
Site Public Contact · Contact
225-765-7659research@ololrmc.com
Marshall P. Stagg · Principal Investigator

Mary Bird Perkins Cancer Center

Baton Rouge, Louisiana, 70809

Recruiting
Site Public Contact · Contact
225-215-1353clinicalresearch@marybird.com
Victor T. Lin · Principal Investigator

Mary Bird Perkins Cancer Center - Metairie

Metairie, Louisiana, 70002

Recruiting
Site Public Contact · Contact
504-584-6990
Victor T. Lin · Principal Investigator

East Jefferson General Hospital

Metairie, Louisiana, 70006

Recruiting
Site Public Contact · Contact
504-210-3539emede1@lsuhsc.edu
Augusto C. Ochoa · Principal Investigator

LSU Healthcare Network / Metairie Multi-Specialty Clinic

Metairie, Louisiana, 70006

Recruiting
Site Public Contact · Contact
504-210-3539emede1@lsuhsc.edu
Augusto C. Ochoa · Principal Investigator

Tulane University School of Medicine

New Orleans, Louisiana, 70112

Recruiting
Site Public Contact · Contact
504-988-1147bweimer1@tulane.edu
Audrey Dang · Principal Investigator

Ochsner Medical Center Jefferson

New Orleans, Louisiana, 70121

Recruiting
Site Public Contact · Contact
504-842-8084Elisemarie.curry@ochsner.org
Troy G. Scroggins · Principal Investigator

Lafayette Family Cancer Center-EMMC

Brewer, Maine, 04412

Recruiting
Site Public Contact · Contact
800-987-3005
Sarah J. Sinclair · Principal Investigator

Massachusetts General Hospital Cancer Center

Boston, Massachusetts, 02114

Recruiting
Site Public Contact · Contact
877-726-5130
Jason A. Efstathiou · Principal Investigator

Brigham and Women's Hospital

Boston, Massachusetts, 02115

Recruiting
Site Public Contact · Contact
617-724-5200
Paul L. Nguyen · Principal Investigator

Dana-Farber Cancer Institute

Boston, Massachusetts, 02215

Recruiting
Site Public Contact · Contact
877-442-3324
Paul L. Nguyen · Principal Investigator

Trinity Health Saint Joseph Mercy Hospital Ann Arbor

Ann Arbor, Michigan, 48106

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Samir Narayan · Principal Investigator

Trinity Health Medical Center - Brighton

Brighton, Michigan, 48114

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Samir Narayan · Principal Investigator

Trinity Health Medical Center - Canton

Canton, Michigan, 48188

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Samir Narayan · Principal Investigator

Chelsea Hospital

Chelsea, Michigan, 48118

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Samir Narayan · Principal Investigator

Henry Ford Hospital

Detroit, Michigan, 48202

Recruiting
Site Public Contact · Contact
313-916-3721CTOResearch@hfhs.org
Eleanor M. Walker · Principal Investigator

McLaren Cancer Institute-Flint

Flint, Michigan, 48532

Active Not Recruiting

Singh and Arora Hematology Oncology PC

Flint, Michigan, 48532

Active Not Recruiting

Karmanos Cancer Institute at McLaren Greater Lansing

Lansing, Michigan, 48910

Active Not Recruiting

Mid-Michigan Physicians-Lansing

Lansing, Michigan, 48912

Active Not Recruiting

University of Michigan Health - Sparrow Lansing

Lansing, Michigan, 48912

Recruiting
Site Public Contact · Contact
517-364-3712harsha.trivedi@umhsparrow.org
Samir Narayan · Principal Investigator

Trinity Health Saint Mary Mercy Livonia Hospital

Livonia, Michigan, 48154

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Samir Narayan · Principal Investigator

McLaren Cancer Institute-Macomb

Mount Clemens, Michigan, 48043

Active Not Recruiting

McLaren Cancer Institute-Owosso

Owosso, Michigan, 48867

Active Not Recruiting

Trinity Health Saint Joseph Mercy Oakland Hospital

Pontiac, Michigan, 48341

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Samir Narayan · Principal Investigator

Minnesota Oncology - Burnsville

Burnsville, Minnesota, 55337

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Mercy Hospital

Coon Rapids, Minnesota, 55433

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Fairview Southdale Hospital

Edina, Minnesota, 55435

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Unity Hospital

Fridley, Minnesota, 55432

Active Not Recruiting

Fairview Clinics and Surgery Center Maple Grove

Maple Grove, Minnesota, 55369

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Minnesota Oncology Hematology PA-Maplewood

Maplewood, Minnesota, 55109

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Saint John's Hospital - Healtheast

Maplewood, Minnesota, 55109

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Hennepin County Medical Center

Minneapolis, Minnesota, 55415

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Monticello Cancer Center

Monticello, Minnesota, 55362

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

North Memorial Medical Health Center

Robbinsdale, Minnesota, 55422

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Coborn Cancer Center at Saint Cloud Hospital

Saint Cloud, Minnesota, 56303

Recruiting
Site Public Contact · Contact
877-229-4907coborncancercenter@centracare.com
Donald J. Jurgens · Principal Investigator

Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Regions Hospital

Saint Paul, Minnesota, 55101

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

United Hospital

Saint Paul, Minnesota, 55102

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Saint Francis Regional Medical Center

Shakopee, Minnesota, 55379

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Lakeview Hospital

Stillwater, Minnesota, 55082

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Ridgeview Medical Center

Waconia, Minnesota, 55387

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Rice Memorial Hospital

Willmar, Minnesota, 56201

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Minnesota Oncology Hematology PA-Woodbury

Woodbury, Minnesota, 55125

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Mercy Oncology and Hematology - Clayton-Clarkson

Ballwin, Missouri, 63011

Suspended

Saint Francis Medical Center

Cape Girardeau, Missouri, 63703

Recruiting
Site Public Contact · Contact
573-334-2230sfmc@sfmc.net
Bryan A. Faller · Principal Investigator

Siteman Cancer Center at Saint Peters Hospital

City of Saint Peters, Missouri, 63376

Recruiting
Site Public Contact · Contact
800-600-3606info@siteman.wustl.edu
Jeff M. Michalski · Principal Investigator

MU Health - University Hospital/Ellis Fischel Cancer Center

Columbia, Missouri, 65212

Recruiting
Site Public Contact · Contact
573-882-7440
Gregory B. Biedermann · Principal Investigator

Siteman Cancer Center at West County Hospital

Creve Coeur, Missouri, 63141

Recruiting
Site Public Contact · Contact
800-600-3606info@siteman.wustl.edu
Jeff M. Michalski · Principal Investigator

Freeman Health System

Joplin, Missouri, 64804

Recruiting
Site Public Contact · Contact
417-347-4030LJCrockett@freemanhealth.com
Jay W. Carlson · Principal Investigator

University of Kansas Cancer Center - Briarcliff

Kansas City, Missouri, 64116

Recruiting
Site Public Contact · Contact
913-588-3671
Xinglei Shen · Principal Investigator

University of Kansas Cancer Center - North

Kansas City, Missouri, 64154

Recruiting
Site Public Contact · Contact
913-588-3671KUCC_Navigation@kumc.edu
Xinglei Shen · Principal Investigator

University of Kansas Cancer Center - Lee's Summit

Lee's Summit, Missouri, 64064

Recruiting
Site Public Contact · Contact
913-588-3671KUCC_Navigation@kumc.edu
Xinglei Shen · Principal Investigator

University of Kansas Cancer Center at North Kansas City Hospital

North Kansas City, Missouri, 64116

Recruiting
Site Public Contact · Contact
913-588-3671KUCC_Navigation@kumc.edu
Xinglei Shen · Principal Investigator

Washington University School of Medicine

St Louis, Missouri, 63110

Recruiting
Site Public Contact · Contact
800-600-3606info@siteman.wustl.edu
Jeff M. Michalski · Principal Investigator

Siteman Cancer Center-South County

St Louis, Missouri, 63129

Recruiting
Site Public Contact · Contact
800-600-3606info@siteman.wustl.edu
Jeff M. Michalski · Principal Investigator

Siteman Cancer Center at Christian Hospital

St Louis, Missouri, 63136

Recruiting
Site Public Contact · Contact
800-600-3606info@siteman.wustl.edu
Jeff M. Michalski · Principal Investigator

Mercy Hospital Saint Louis

St Louis, Missouri, 63141

Recruiting
Site Public Contact · Contact
314-251-7066
Jay W. Carlson · Principal Investigator

Billings Clinic Cancer Center

Billings, Montana, 59101

Recruiting
Site Public Contact · Contact
800-996-2663research@billingsclinic.org
John M. Schallenkamp · Principal Investigator

Benefis Sletten Cancer Institute

Great Falls, Montana, 59405

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Cancer Partners of Nebraska

Lincoln, Nebraska, 68516

Recruiting
Site Public Contact · Contact
402-327-7363research@cancerpartners.com
Mark J. Stavas · Principal Investigator

Comprehensive Cancer Centers of Nevada - Henderson

Henderson, Nevada, 89052

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

OptumCare Cancer Care at Seven Hills

Henderson, Nevada, 89052

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

Oncology Las Vegas - Henderson

Henderson, Nevada, 89074

Suspended

OptumCare Cancer Care at Charleston

Las Vegas, Nevada, 89102

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

Radiation Oncology Centers of Nevada Central

Las Vegas, Nevada, 89106

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

Radiation Oncology Centers of Nevada Southeast

Las Vegas, Nevada, 89119

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

Comprehensive Cancer Centers of Nevada - Northwest

Las Vegas, Nevada, 89128

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

Oncology Las Vegas - Tenaya

Las Vegas, Nevada, 89128

Suspended

OptumCare Cancer Care at MountainView

Las Vegas, Nevada, 89128

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

Comprehensive Cancer Centers of Nevada - Town Center

Las Vegas, Nevada, 89144

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

Comprehensive Cancer Centers of Nevada-Summerlin

Las Vegas, Nevada, 89144

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

Summerlin Hospital Medical Center

Las Vegas, Nevada, 89144

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

Comprehensive Cancer Centers of Nevada

Las Vegas, Nevada, 89148

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

OptumCare Cancer Care at Fort Apache

Las Vegas, Nevada, 89148

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

Comprehensive Cancer Centers of Nevada - Central Valley

Las Vegas, Nevada, 89169

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

Renown Regional Medical Center

Reno, Nevada, 89502

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

New Hampshire Oncology Hematology PA-Concord

Concord, New Hampshire, 03301

Recruiting
Site Public Contact · Contact
603-224-2556
Josy Mathew · Principal Investigator

Solinsky Center for Cancer Care

Manchester, New Hampshire, 03103

Recruiting
Site Public Contact · Contact
800-339-6484
Josy Mathew · Principal Investigator

Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, 07920

Recruiting
Site Public Contact · Contact
212-639-7592
Justin M. Haseltine · Principal Investigator

Cooper Hospital University Medical Center

Camden, New Jersey, 08103

Recruiting
Site Public Contact · Contact
856-325-6757
Gary Eastwick · Principal Investigator

Saint Barnabas Medical Center

Livingston, New Jersey, 07039

Recruiting
Site Public Contact · Contact
973-322-2934joanne.loeb@rwjbh.org
Lara Hathout · Principal Investigator

Memorial Sloan Kettering Monmouth

Middletown, New Jersey, 07748

Recruiting
Site Public Contact · Contact
212-639-7592
Justin M. Haseltine · Principal Investigator

Memorial Sloan Kettering Bergen

Montvale, New Jersey, 07645

Recruiting
Site Public Contact · Contact
212-639-7592
Justin M. Haseltine · Principal Investigator

Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, 08903

Recruiting
Site Public Contact · Contact
732-235-7356
Lara Hathout · Principal Investigator

Rutgers New Jersey Medical School

Newark, New Jersey, 07101

Recruiting
Site Public Contact · Contact
732-235-7356
Lara Hathout · Principal Investigator

Robert Wood Johnson University Hospital Somerset

Somerville, New Jersey, 08876

Recruiting
Site Public Contact · Contact
908-685-2481Siby.Varughese@rwjbh.org
Lara Hathout · Principal Investigator

MD Anderson Cancer Center at Cooper-Voorhees

Voorhees Township, New Jersey, 08043

Recruiting
Site Public Contact · Contact
856-325-6757
Gary Eastwick · Principal Investigator

Sands Cancer Center

Canandiaqua, New York, 14424

Recruiting
Site Public Contact · Contact
585-396-6161
Hong Zhang · Principal Investigator

Memorial Sloan Kettering Commack

Commack, New York, 11725

Recruiting
Site Public Contact · Contact
212-639-7592
Justin M. Haseltine · Principal Investigator

Memorial Sloan Kettering Westchester

East White Plains, New York, 10604

Recruiting
Site Public Contact · Contact
212-639-7592
Justin M. Haseltine · Principal Investigator

Northwell Health Physicians Partners Radiation Medicine at Queens

Forest Hills, New York, 11375

Recruiting
Site Public Contact · Contact
718-520-6620
Bhupesh Parashar · Principal Investigator

Northwell Health/Center for Advanced Medicine

Lake Success, New York, 11042

Recruiting
Site Public Contact · Contact
516-734-8896
Bhupesh Parashar · Principal Investigator

Garnet Health Medical Center

Middletown, New York, 10940

Recruiting
Site Public Contact · Contact
845-333-1133jgerlach@garnethealth.org
Jeffrey M. Stewart · Principal Investigator

Memorial Sloan Kettering Cancer Center

New York, New York, 10065

Recruiting
Site Public Contact · Contact
212-639-7592
Justin M. Haseltine · Principal Investigator

Queens Cancer Center

Rego Park, New York, 11374

Recruiting
Site Public Contact · Contact
718-312-3446
Bhupesh Parashar · Principal Investigator

Wilmot Cancer Institute Radiation Oncology at Greece

Rochester, New York, 14606

Recruiting
Site Public Contact · Contact
585-758-7877
Hong Zhang · Principal Investigator

Highland Hospital

Rochester, New York, 14620

Recruiting
Site Public Contact · Contact
585-341-8113
Hong Zhang · Principal Investigator

University of Rochester

Rochester, New York, 14642

Recruiting
Site Public Contact · Contact
585-275-5830
Hong Zhang · Principal Investigator

Memorial Sloan Kettering Nassau

Uniondale, New York, 11553

Recruiting
Site Public Contact · Contact
212-639-7592
Justin M. Haseltine · Principal Investigator

Wilmot Cancer Institute at Webster

Webster, New York, 14580

Recruiting
Site Public Contact · Contact
WCICTOresearch@urmc.rochester.edu
Hong Zhang · Principal Investigator

Duke Cancer Center Cary

Cary, North Carolina, 27518

Recruiting
Site Public Contact · Contact
NCTNStudyTeam@dm.duke.edu
Paul P. Koffer · Principal Investigator

Duke University Medical Center

Durham, North Carolina, 27710

Recruiting
Site Public Contact · Contact
888-275-3853
Paul P. Koffer · Principal Investigator

Duke Cancer Center Raleigh

Raleigh, North Carolina, 27609

Recruiting
Site Public Contact · Contact
NCTNStudyTeam@dm.duke.edu
Paul P. Koffer · Principal Investigator

Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157

Recruiting
Site Public Contact · Contact
336-713-6771
Michael McCormack · Principal Investigator

Altru Cancer Center

Grand Forks, North Dakota, 58201

Recruiting
Site Public Contact · Contact
701-780-6520
Grant R. Seeger · Principal Investigator

Cleveland Clinic Akron General

Akron, Ohio, 44307

Recruiting
Site Public Contact · Contact
866-223-8100CancerAnswer@ccf.org
Salem A. Alfaifi · Principal Investigator

Miami Valley Hospital South

Centerville, Ohio, 45459

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Tarek M. Sabagh · Principal Investigator

University of Cincinnati Cancer Center-UC Medical Center

Cincinnati, Ohio, 45219

Recruiting
Site Public Contact · Contact
513-584-7698cancer@uchealth.com
Timothy D. Struve · Principal Investigator

Cleveland Clinic Cancer Center/Fairview Hospital

Cleveland, Ohio, 44111

Recruiting
Site Public Contact · Contact
866-223-8100TaussigResearch@ccf.org
Andrew D. Vassil · Principal Investigator

Cleveland Clinic Foundation

Cleveland, Ohio, 44195

Recruiting
Site Public Contact · Contact
866-223-8100TaussigResearch@ccf.org
Andrew D. Vassil · Principal Investigator

Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210

Recruiting
Site Public Contact · Contact
800-293-5066Jamesline@osumc.edu
Shang-Jui Wang · Principal Investigator

Miami Valley Hospital

Dayton, Ohio, 45409

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Tarek M. Sabagh · Principal Investigator

Premier Blood and Cancer Center

Dayton, Ohio, 45409

Recruiting
Site Public Contact · Contact
937-276-8320
Tarek M. Sabagh · Principal Investigator

Miami Valley Hospital North

Dayton, Ohio, 45415

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Tarek M. Sabagh · Principal Investigator

Armes Family Cancer Center

Findlay, Ohio, 45840

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Howard M. Gross · Principal Investigator

Atrium Medical Center-Middletown Regional Hospital

Franklin, Ohio, 45005-1066

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Tarek M. Sabagh · Principal Investigator

Cleveland Clinic Cancer Center Mansfield

Mansfield, Ohio, 44906

Recruiting
Site Public Contact · Contact
866-223-8100TaussigResearch@ccf.org
Andrew D. Vassil · Principal Investigator

Hillcrest Hospital Cancer Center

Mayfield Heights, Ohio, 44124

Recruiting
Site Public Contact · Contact
866-223-8100TaussigResearch@ccf.org
Andrew D. Vassil · Principal Investigator

North Coast Cancer Care

Sandusky, Ohio, 44870

Recruiting
Site Public Contact · Contact
866-223-8100TaussigResearch@ccf.org
Andrew D. Vassil · Principal Investigator

Cleveland Clinic Cancer Center Strongsville

Strongsville, Ohio, 44136

Recruiting
Site Public Contact · Contact
866-223-8100TaussigResearch@ccf.org
Andrew D. Vassil · Principal Investigator

Upper Valley Medical Center

Troy, Ohio, 45373

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Tarek M. Sabagh · Principal Investigator

University of Cincinnati Cancer Center-West Chester

West Chester, Ohio, 45069

Recruiting
Site Public Contact · Contact
513-584-7698cancer@uchealth.com
Timothy D. Struve · Principal Investigator

Cleveland Clinic Wooster Family Health and Surgery Center

Wooster, Ohio, 44691

Recruiting
Site Public Contact · Contact
866-223-8100TaussigResearch@ccf.org
Andrew D. Vassil · Principal Investigator

University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104

Recruiting
Site Public Contact · Contact
405-271-8777ou-clinical-trials@ouhsc.edu
Tyler Gunter · Principal Investigator

Legacy Mount Hood Medical Center

Gresham, Oregon, 97030

Active Not Recruiting

Legacy Good Samaritan Hospital and Medical Center

Portland, Oregon, 97210

Active Not Recruiting

UPMC Altoona

Altoona, Pennsylvania, 16601

Recruiting
Site Public Contact · Contact
412-339-5294Roster@nrgoncology.org
Adam Olson · Principal Investigator

UPMC-Heritage Valley Health System Beaver

Beaver, Pennsylvania, 15009

Recruiting
Site Public Contact · Contact
412-389-5208haneydl@upmc.edu
Adam Olson · Principal Investigator

Crozer-Keystone Regional Cancer Center at Broomall

Broomall, Pennsylvania, 19008

Suspended

Carlisle Regional Cancer Center

Carlisle, Pennsylvania, 17015

Recruiting
Site Public Contact · Contact
412-339-5294Roster@nrgoncology.org
Adam Olson · Principal Investigator

Christiana Care Health System-Concord Health Center

Chadds Ford, Pennsylvania, 19317

Recruiting
Site Public Contact · Contact
302-623-4450lbarone@christianacare.org
Gregory A. Masters · Principal Investigator

Delaware County Memorial Hospital

Drexel Hill, Pennsylvania, 19026

Suspended

UPMC Hillman Cancer Center Erie

Erie, Pennsylvania, 16505

Recruiting
Site Public Contact · Contact
412-864-7716ClinicalResearchServices@upmc.edu
Adam Olson · Principal Investigator

UPMC Cancer Center at UPMC Horizon

Farrell, Pennsylvania, 16121

Recruiting
Site Public Contact · Contact
412-339-5294Roster@nrgoncology.org
Adam Olson · Principal Investigator

Crozer Regional Cancer Center at Brinton Lake

Glen Mills, Pennsylvania, 19342

Suspended

UPMC Cancer Centers - Arnold Palmer Pavilion

Greensburg, Pennsylvania, 15601

Recruiting
Site Public Contact · Contact
724-838-1900
Adam Olson · Principal Investigator

UPMC Pinnacle Cancer Center/Community Osteopathic Campus

Harrisburg, Pennsylvania, 17109

Recruiting
Site Public Contact · Contact
717-724-6765klitchfield@PINNACLEHEALTH.org
Adam Olson · Principal Investigator

Penn State Milton S Hershey Medical Center

Hershey, Pennsylvania, 17033-0850

Recruiting
Site Public Contact · Contact
717-531-3779CTO@hmc.psu.edu
Joseph A. Miccio · Principal Investigator

IRMC Cancer Center

Indiana, Pennsylvania, 15701

Recruiting
Site Public Contact · Contact
412-389-5208haneydl@upmc.edu
Adam Olson · Principal Investigator

UPMC-Johnstown/John P. Murtha Regional Cancer Center

Johnstown, Pennsylvania, 15901

Recruiting
Site Public Contact · Contact
814-534-4724
Adam Olson · Principal Investigator

UPMC Cancer Center at UPMC McKeesport

McKeesport, Pennsylvania, 15132

Recruiting
Site Public Contact · Contact
412-647-8073
Adam Olson · Principal Investigator

UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion

Mechanicsburg, Pennsylvania, 17050

Recruiting
Site Public Contact · Contact
412-389-5208haneydl@upmc.edu
Adam Olson · Principal Investigator

UPMC Cancer Center - Monroeville

Monroeville, Pennsylvania, 15146

Recruiting
Site Public Contact · Contact
412-339-5294Roster@nrgoncology.org
Adam Olson · Principal Investigator

UPMC Hillman Cancer Center in Coraopolis

Moon Township, Pennsylvania, 15108

Recruiting
Site Public Contact · Contact
412-389-5208haneydl@upmc.edu
Adam Olson · Principal Investigator

UPMC-Magee Womens Hospital

Pittsburgh, Pennsylvania, 15213

Recruiting
Site Public Contact · Contact
412-647-2811
Adam Olson · Principal Investigator

UPMC-Saint Margaret

Pittsburgh, Pennsylvania, 15215

Recruiting
Site Public Contact · Contact
412-784-4900
Adam Olson · Principal Investigator

UPMC-Shadyside Hospital

Pittsburgh, Pennsylvania, 15232

Recruiting
Site Public Contact · Contact
412-621-2334
Adam Olson · Principal Investigator

UPMC-Passavant Hospital

Pittsburgh, Pennsylvania, 15237

Recruiting
Site Public Contact · Contact
412-367-6454
Adam Olson · Principal Investigator

UPMC-Saint Clair Hospital Cancer Center

Pittsburgh, Pennsylvania, 15243

Recruiting
Site Public Contact · Contact
412-502-3920
Adam Olson · Principal Investigator

UPMC Cancer Center at UPMC Northwest

Seneca, Pennsylvania, 16346

Recruiting
Site Public Contact · Contact
814-676-7900
Adam Olson · Principal Investigator

UPMC Uniontown Hospital Radiation Oncology

Uniontown, Pennsylvania, 15401

Recruiting
Site Public Contact · Contact
724-437-2503
Adam Olson · Principal Investigator

Crozer-Chester Medical Center

Upland, Pennsylvania, 19013

Suspended

UPMC Washington Hospital Radiation Oncology

Washington, Pennsylvania, 15301

Recruiting
Site Public Contact · Contact
724-223-3788cancer@washingtonhospital.org
Adam Olson · Principal Investigator

Chester County Hospital

West Chester, Pennsylvania, 19380

Recruiting
Site Public Contact · Contact
610-431-5044carolann.hoppes@pennmedicine.upenn.edu
Andre A. Konski · Principal Investigator

Reading Hospital

West Reading, Pennsylvania, 19611

Recruiting
Site Public Contact · Contact
610-988-9323
Terrence P. Cescon · Principal Investigator

UPMC Memorial

York, Pennsylvania, 17408

Recruiting
Site Public Contact · Contact
717-724-6760
Adam Olson · Principal Investigator

Avera Cancer Institute - Mitchell

Mitchell, South Dakota, 57301

Recruiting
Site Public Contact · Contact
605-322-3096OncRegulatory@avera.org
Ryan A. Vaca · Principal Investigator

Avera Cancer Institute at Pierre

Pierre, South Dakota, 57501

Recruiting
Site Public Contact · Contact
605-322-3095OncRegulatory@avera.org
Ryan A. Vaca · Principal Investigator

Avera Cancer Institute

Sioux Falls, South Dakota, 57105

Recruiting
Site Public Contact · Contact
605-322-3095OncRegulatory@avera.org
Ryan A. Vaca · Principal Investigator

Parkland Memorial Hospital

Dallas, Texas, 75235

Recruiting
Site Public Contact · Contact
214-590-5582canceranswerline@UTSouthwestern.edu
Aurelie Garant · Principal Investigator

UT Southwestern/Simmons Cancer Center-Dallas

Dallas, Texas, 75390

Recruiting
Site Public Contact · Contact
214-648-7097canceranswerline@UTSouthwestern.edu
Aurelie Garant · Principal Investigator

Tarrant County Hospital District/JPS Health Network

Fort Worth, Texas, 76104

Recruiting
Site Public Contact · Contact
817-702-5913macosta02@jpshealth.org
Solomon L. Woldu · Principal Investigator

UT Southwestern/Simmons Cancer Center-Fort Worth

Fort Worth, Texas, 76104

Recruiting
Site Public Contact · Contact
214-648-7097canceranswerline@UTSouthwestern.edu
Aurelie Garant · Principal Investigator

UT Southwestern Clinical Center at Richardson/Plano

Richardson, Texas, 75080

Recruiting
Site Public Contact · Contact
972-669-7044Suzanne.cole@utsouthwestern.edu
Aurelie Garant · Principal Investigator

Audie L Murphy VA Hospital

San Antonio, Texas, 78229

Active Not Recruiting

VCU Massey Cancer Center at Hanover Medical Park

Mechanicsville, Virginia, 23116

Recruiting
Site Public Contact · Contact
CTOclinops@vcu.edu
Alfredo I. Urdaneta · Principal Investigator

Bon Secours Saint Francis Medical Center

Midlothian, Virginia, 23114

Recruiting
Site Public Contact · Contact
804-893-8978anne_carmellat@bshsi.org
Joseph D. Pennington · Principal Investigator

Bon Secours Cancer Institute at Reynolds Crossing

Richmond, Virginia, 23230

Recruiting
Site Public Contact · Contact
804-893-8978Anne_caramella@bshsi.org
Joseph D. Pennington · Principal Investigator

VCU Massey Cancer Center at Stony Point

Richmond, Virginia, 23235

Recruiting
Site Public Contact · Contact
ctoclinops@vcu.edu
Alfredo I. Urdaneta · Principal Investigator

VCU Massey Comprehensive Cancer Center

Richmond, Virginia, 23298

Recruiting
Site Public Contact · Contact
804-628-6430CTOclinops@vcu.edu
Alfredo I. Urdaneta · Principal Investigator

Legacy Salmon Creek Hospital

Vancouver, Washington, 98686

Active Not Recruiting

West Virginia University Charleston Division

Charleston, West Virginia, 25304

Recruiting
Site Public Contact · Contact
304-388-9944
Ahmed A. Khalid · Principal Investigator

Langlade Hospital and Cancer Center

Antigo, Wisconsin, 54409

Recruiting
Site Public Contact · Contact
715-623-9869Juli.Alford@aspirus.org
Andrew J. Huang · Principal Investigator

ThedaCare Regional Cancer Center

Appleton, Wisconsin, 54911

Recruiting
Site Public Contact · Contact
920-364-3604ResearchDept@thedacare.org
Michael E. Ray · Principal Investigator

Aurora Cancer Care-Southern Lakes VLCC

Burlington, Wisconsin, 53105

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Adam P. Siegel · Principal Investigator

Marshfield Medical Center-EC Cancer Center

Eau Claire, Wisconsin, 54701

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

Aurora Health Care Germantown Health Center

Germantown, Wisconsin, 53022

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Adam P. Siegel · Principal Investigator

Aurora Cancer Care-Grafton

Grafton, Wisconsin, 53024

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Adam P. Siegel · Principal Investigator

Bellin Memorial Hospital

Green Bay, Wisconsin, 54301

Recruiting
Site Public Contact · Contact
920-435-8326
Adam L. Liss · Principal Investigator

Aurora BayCare Medical Center

Green Bay, Wisconsin, 54311

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Adam P. Siegel · Principal Investigator

Aurora Cancer Care-Kenosha South

Kenosha, Wisconsin, 53142

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Adam P. Siegel · Principal Investigator

Aurora Bay Area Medical Group-Marinette

Marinette, Wisconsin, 54143

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Adam P. Siegel · Principal Investigator

Marshfield Medical Center-Marshfield

Marshfield, Wisconsin, 54449

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

Froedtert Menomonee Falls Hospital

Menomonee Falls, Wisconsin, 53051

Recruiting
Site Public Contact · Contact
262-257-5100
William A. Hall · Principal Investigator

Aurora Cancer Care-Milwaukee

Milwaukee, Wisconsin, 53209

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Adam P. Siegel · Principal Investigator

Aurora Saint Luke's Medical Center

Milwaukee, Wisconsin, 53215

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Adam P. Siegel · Principal Investigator

Medical College of Wisconsin

Milwaukee, Wisconsin, 53226

Recruiting
Site Public Contact · Contact
414-805-3666
William A. Hall · Principal Investigator

Aurora Sinai Medical Center

Milwaukee, Wisconsin, 53233

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Adam P. Siegel · Principal Investigator

Marshfield Medical Center - Minocqua

Minocqua, Wisconsin, 54548

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

Cancer Center of Western Wisconsin

New Richmond, Wisconsin, 54017

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Charles Shideman · Principal Investigator

Drexel Town Square Health Center

Oak Creek, Wisconsin, 53154

Recruiting
Site Public Contact · Contact
414-805-0505
William A. Hall · Principal Investigator

Vince Lombardi Cancer Clinic - Oshkosh

Oshkosh, Wisconsin, 54904

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Adam P. Siegel · Principal Investigator

Aurora Cancer Care-Racine

Racine, Wisconsin, 53406

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Adam P. Siegel · Principal Investigator

Aspirus Cancer Care - James Beck Cancer Center

Rhinelander, Wisconsin, 54501

Recruiting
Site Public Contact · Contact
715-847-2353Beth.Knetter@aspirus.org
Andrew J. Huang · Principal Investigator

Marshfield Medical Center-Rice Lake

Rice Lake, Wisconsin, 54868

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

Vince Lombardi Cancer Clinic-Sheboygan

Sheboygan, Wisconsin, 53081

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Adam P. Siegel · Principal Investigator

Aspirus Cancer Care - Stevens Point

Stevens Point, Wisconsin, 54481

Recruiting
Site Public Contact · Contact
715-847-2353Beth.Knetter@aspirus.org
Andrew J. Huang · Principal Investigator

Marshfield Medical Center-River Region at Stevens Point

Stevens Point, Wisconsin, 54482

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

Aurora Medical Center in Summit

Summit, Wisconsin, 53066

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Adam P. Siegel · Principal Investigator

Aspirus Regional Cancer Center

Wausau, Wisconsin, 54401

Recruiting
Site Public Contact · Contact
877-405-6866
Andrew J. Huang · Principal Investigator

Aurora Cancer Care-Milwaukee West

Wauwatosa, Wisconsin, 53226

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Adam P. Siegel · Principal Investigator

Aurora West Allis Medical Center

West Allis, Wisconsin, 53227

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Adam P. Siegel · Principal Investigator

Froedtert West Bend Hospital/Kraemer Cancer Center

West Bend, Wisconsin, 53095

Recruiting
Site Public Contact · Contact
414-805-0505
William A. Hall · Principal Investigator

Marshfield Medical Center - Weston

Weston, Wisconsin, 54476

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

Aspirus Cancer Care - Wisconsin Rapids

Wisconsin Rapids, Wisconsin, 54494

Recruiting
Site Public Contact · Contact
715-422-7718
Andrew J. Huang · Principal Investigator

References

  • Morgan TM, Boorjian SA, Buyyounouski MK, Chapin BF, Chen DYT, Cheng HH, Chou R, Jacene HA, Kamran SC, Kim SK, Kirkby E, Luckenbaugh AN, Nathanson BJ, Nyame YA, Posadas EM, Tran PT, Chen RC. Salvage Therapy for Prostate Cancer: AUA/ASTRO/SUO Guideline Part II: Treatment Delivery for Non-metastatic Biochemical Recurrence After Primary Radical Prostatectomy. J Urol. 2024 Apr;211(4):518-525. doi: 10.1097/JU.0000000000003891. Epub 2024 Feb 29.(PubMed)
Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer, INNOVATE Trial | Cancerify