Proton Radiation Therapy Registry
Summary
The Johns Hopkins Proton Therapy center is establishing a registry to capture the full 3D radiation dosimetry delivered to the patient, baseline clinical data, and disease, toxicity and quality of life outcomes. The goal is to have all patients treated at the proton center to be included in the registry to enable future comparisons of treatment outcomes to assist in understanding which patients can benefit from the use of protons.
Detailed description
Proton based radiation therapy has considerable dosimetric advantages over the standard photon based radiation therapy, with a significantly higher cost. The clinical advantages, however, may not be realized for all patient populations, even with the improved dose distributions. Establishing the clinical efficacy of proton therapy requires years of experience treating patients. The goal is to accelerate the knowledge gain through the use of the registry that allows for detailed information to be captured and is inclusive of every patient treated.
Arms & interventions
- OtherRegistry
Registry of cancer patients who receive proton radiation therapy
Outcome measures
Primary
Research registry of cancer patients receiving proton radiation therapy
This is a clinic based registry of cancer patients' data from participants to be collected over 15 years. The registry will be populated with 3D anatomy and radiation dosimetry from the RayStation treatment planning system used to plan all proton therapy patients. Clinical data will be extracted electronically from the MOSAIQ oncology information system used to manage the radiation therapy treatments. Structured clinical assessments will be routinely captured in the clinical workflow during patient encounters. Patient reported outcomes will be captured with iPad's using the OncoBrowser tools developed in radiotherapy that also interface with MOSAIQ.
Time frame: 15 years
Eligibility criteria
Study locations (4)
Sibley Memorial Hospital
Washington D.C., District of Columbia, 20016
Suburban Hospital
Washington D.C., District of Columbia, 20814
Bayview Hospital
Baltimore, Maryland, 21224
Johns Hopkins Hospital
Baltimore, Maryland, 21287