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RecruitingObservational

Young Onset Gastrointestinal Cancer Prospective Registry

NCT ID: NCT04489238Sponsor: Memorial Sloan Kettering Cancer CenterLast updated: 2026-02-06

Summary

The purpose of this registry study is to create a database-a collection of information-for better understanding young onset colorectal cancer. Colorectal cancer patients are considered to have young onset colorectal cancer if they are diagnosed with their cancer before the age of 50. Researchers will use the information from this database to learn more about how young onset colorectal cancer may be similar to or different from colorectal cancer that is diagnosed later in life. Researchers will also use information from the database for current and future research on young onset colorectal cancer.

Arms & interventions

  • OtherRisk Factor Questionnaire

    Participants, both cases and controls, will complete the CYOC risk factor questionnaire, preferably at the time of first visit

Outcome measures

Primary

  • Establish a prospective database of patients with Young Onset Colorectal Cancer

    from diagnosis through survivorship

    Time frame: 1 year

Eligibility criteria

Sex: AllAge: 18 Years and olderHealthy volunteers: No
Inclusion Criteria: Participant Inclusion Criteria for database and questionnaire (YOGI) * Histological or cytological diagnosis of gastrointestinal cancer * 18 - 49 years old at time of consent * No Known hereditary CRC or other cancer predisposition syndrome (stool collection cohort only) * No history of inflammatory bowel disease (stool collection cohort only) * No prior diagnosis of gastrointestinal cancer (stool collection cohort only) Participant Inclusion Criteria for database and questionnaire (Controls) * Histological or cytological diagnosis of colorectal adenocarcinoma * No previous treatment for CRC (including surgery, chemotherapy, immunotherapy or radiation) * Age 50 or older at time of consent * No Known hereditary CRC or other cancer predisposition syndrome * No history of inflammatory bowel disease * No prior diagnosis of CRC

Study locations (8)

Memorial Sloan Kettering Basking Ridge (All Protocol Activities)

Basking Ridge, New Jersey, 07920

Recruiting
Andrea Cercek, MD · Contact
646-888-4189

Memorial Sloan Kettering Monmouth

Middletown, New Jersey, 07748

Recruiting
Andrea Cercek, MD · Contact
646-888-4189

Memorial Sloan Kettering Bergen

Montvale, New Jersey, 07645

Recruiting
Andrea Cercek, MD · Contact
646-888-4189

Memorial Sloan Kettering Cancer Center @ Commack

Commack, New York, 11725

Recruiting
Andrea Cercek, MD · Contact
646-888-4189

Memorial Sloan Kettering Westchester

Harrison, New York, 10604

Recruiting
Andrew Cercek, MD · Contact
646-888-4189

MSK at Ralph Lauren

New York, New York, 10035

Recruiting
Andrew Cercek, MD · Contact
646-888-4189

Memorial Sloan Kettering Cancer Center

New York, New York, 10065

Recruiting
Andrew Cercek, MD · Contact
646-888-4189

Memorial Sloan Kettering Nassau

Rockville Centre, New York, 11553

Recruiting
Andrea Cercek, MD · Contact
646-888-4189