Pre and Post-Operative Cognitive Status in Patients Undergoing Surgery for Resection of Meningioma Associated With the Frontal and Temporal Lobes
Summary
The purpose of this prospectively enrolling trial is to assess long-term cognitive outcomes of patients undergoing surgery for resection of a meningioma associated with the frontal and temporal lobes.
Detailed description
This study will look at patients who are undergoing resection of a skull based meningioma, located in the frontal or temporal lobe, via craniotomy or via endoscopic endonasal approach. The study will compare cognitive function at baseline, at six weeks postoperatively and at one year postoperatively. The cognitive testing being done at baseline will be a clinical care set of assessments done by the speech language pathology team and will include the RBANS tests, the MoCA, PROMIS-29, and NeuroQOL-Cognitive Functions.
Arms & interventions
- OtherLong-term Cognitive testing
These patients will undergo their standard of care cognitive testing at baseline, six weeks post-operatively and one year post-operatively.
Outcome measures
Primary
Overall cognitive function
Cognitive function will be compared at baseline and at one year post-operatively.
Time frame: 12 months
Secondary
Cognitive function based on surgical approach using Repeatable Battery for the Assessment of Neuropsychological Status (RBANS)
Time frame: 12 months
Cognitive function based on tumor location using Repeatable Battery for the Assessment of Neuropsychological Status (RBANS)
Time frame: 12 months
Eligibility criteria
Study locations (1)
Ohio State University Wexner Medical Center
Columbus, Ohio, 43210