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RecruitingObservational

Sinonasal Cancer Study to Evaluate Oncologic Outcomes and Quality of Life

NCT ID: NCT04755855Sponsor: Mayo ClinicLast updated: 2026-04-03

Summary

This is a multi-institution prospective study of patients with sinonasal malignancies. The goal of this study is to learn more about the course of sinonasal cancer, treatment outcomes, and patient quality of life. In addition, central mutational and genomic analysis of tumor tissue will be evaluated.

Outcome measures

Primary

  • Oncologic outcomes as measured by overall survival, disease specific survival and recurrence free survival

    Time frame: Through study completion, an average of 5 years

Secondary

  • Quality of life outcomes including the University of Washington Quality of Life Questionnaire (UW-QOL v4) and the Sinonasal Outcome Test 22 (SNOT22)

    Time frame: Through study completion, an average of 5 years

  • Describe the molecular foundation of sinonasal malignancies utilizing RNA sequencing to identify transcriptomic tumor profiles

    Time frame: Through study completion, an average of 5 years

Eligibility criteria

Sex: AllAge: 30 Days to 99 YearsHealthy volunteers: No
Inclusion Criteria: * Subjects between the ages of 30 days (non-inclusive) and 99 years (inclusive) * Patients with a diagnosis of sinonasal cancer * Patients undergoing treatment at Mayo Clinic Exclusion Criteria: * Healthy individuals * Unwilling to sign the informed consent

Study locations (1)

Mayo Clinic in Rochester

Rochester, Minnesota, 55905

Recruiting
Clinical Trials Referral Office · Contact
Jake Eide, MD · Principal Investigator