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RecruitingObservational

Comparison of Synthetic Mammography Versus Full-Field Digital Mammography in Image Interpretation and Performance Metrics

NCT ID: NCT05056818Sponsor: M.D. Anderson Cancer CenterLast updated: 2026-04-16

Summary

This study compares synthetic mammography to full-field digital mammography in image interpretation and performance metrics. Digital breast tomosynthesis (DBT) has previously been found to be superior in performance to standard digital mammography in both screening and diagnostic settings for the early detection and improved diagnosis of breast cancers. DBT in combination with full-field digital mammography (FFDM) reduces recall rates and increases cancer detection rates relative to FFDM alone. Synthetic mammography is a 2-dimensional reconstructed image, using the dataset derived from the DBT acquisition, without requiring additional radiation dose. Collecting information from patients' medical records may help doctors analyze the characteristics, utility, and impact of synthetic mammography to compared to FFDM.

Detailed description

PRIMARY OBJECTIVE: I. To analyze the characteristics, utility, and impact of synthetic mammography (SM), as compared with full-field digital mammography (FFDM). OUTLINE: Patients' medical records and past imaging examinations are reviewed.

Arms & interventions

  • OtherElectronic Health Record Review

    Review of medical records and past imaging examinations

Outcome measures

Primary

  • To analyze the impact of synthetic mammography (SM), as compared with full-field digital mammography (FFDM

    Time frame: through study completion, an average of 1 year

Eligibility criteria

Sex: FemaleAge: 18 Years and olderHealthy volunteers: No
Inclusion Criteria: * Female * Age 18 or older * Consecutive cases in breast imaging center Exclusion Criteria: * Cases demonstrate administrative or technical errors (e.g. missing views, labeling inconsistent with report, etc.)

Study locations (1)

M D Anderson Cancer Center

Houston, Texas, 77030

Recruiting
Ray C. Mayo · Contact
Ray C. Mayo · Principal Investigator
Comparison of Synthetic Mammography Versus Full-Field Digital Mammography in Image Interpretation and Performance Metrics | Cancerify