Study of Healthy Cohort for Early Detection of Cancer
Summary
Cancer produces a significant burden on society with a majority diagnosed at late stages when the chance of cure is low. Early diagnosis improves patient outcomes. Data consisting of lifestyle factors, medications, physical activity, years before conventional cancer diagnosis is also worthwhile for to determine early detection. This is only achievable with longitudinal tracking of a large number of healthy individuals and identifying those who do develop cancer over time.
Detailed description
To conduct a longitudinal cohort study of patients who do not have a malignancy at the time of enrollment and are followed over a 20 year period to see if patients develop a malignancy and associate clinical and lifestyle factors as well as collection of blood. All adults 18 years of age and older undergoing upper or lower endoscopy for routine medical care will be eligible for this study.
Outcome measures
Primary
Development of malignancy
Assessment of participants for the development of malignancy during a 20-year follow-up period.
Time frame: Up to 20 years
Secondary
Development of biomarkers
Time frame: Up to 20 years
Eligibility criteria
Study locations (1)
Johns Hopkins Hospital
Baltimore, Maryland, 21205