Tempus CRC Surveillance Study: A Longitudinal Circulating Tumor DNA (ctDNA) Biomarker Profiling Study of Patients With Colorectal Cancer (CRC) Using Comprehensive Next-Generation Sequencing (NGS)Assays
Summary
The study is an observational multicenter evaluation of participants with colorectal cancer (CRC) who will receive longitudinal plasma ctDNA biomarker profiling in addition to their standard-of-care therapy and disease surveillance.
Arms & interventions
- OtherObservation
No intervention
Outcome measures
Primary
Recurrence-Free Survival
Recurrence-Free Survival as assessed by standard radiographic imaging, measured from the day of completion of definitive treatment to first radiographic recurrence or death
Time frame: 2 years
Secondary
Sensitivity
Time frame: 2 years
Specificity
Time frame: 2 years
Positive Predictive Value
Time frame: 2 years
Eligibility criteria
Study locations (20)
Mercy Clinic Oncology - Fort Smith
Fort Smith, Arkansas, 72903
MemorialCare
Fountain Valley, California, 92708
The Center for Cancer and Blood Disorders
Bethesda, Maryland, 20817
Mercy Clinic Oncology and Hematology - Joplin
Joplin, Missouri, 64804
Mercy Clinic Cancer and Hematology - Chub O'Reilly Cancer Center
Springfield, Missouri, 65804
Washington University School of Medicine
St Louis, Missouri, 63110
Mercy Clinic Oncology and Hematology - Sindelar Cancer Center
St Louis, Missouri, 63128
Mercy Clinic Oncology and Hematology - David C. Pratt Cancer Center
St Louis, Missouri, 63141
Nebraska Cancer Specialists
Omaha, Nebraska, 68130
Southeastern Medical Oncology Center
Goldsboro, North Carolina, 27543
Aultman Hospital
Canton, Ohio, 44710
TriHealth Cancer Institute
Cincinnati, Ohio, 45220
Ohio State University
Columbus, Ohio, 43210
OhioHealth Research Institute
Columbus, Ohio, 43214
Toledo Clinic Cancer Center
Toledo, Ohio, 43623
Mercy Clinic Oncology and Hematology - Coletta
Oklahoma City, Oklahoma, 73120
Cancer Care Associates of York
York, Pennsylvania, 17403
Utah Cancer Specialists
Salt Lake City, Utah, 84124
University of Washington / Fred Hutchinson Cancer Center
Seattle, Washington, 98109
ThedaCare Regional Cancer Center
Appleton, Wisconsin, 54911
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