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RecruitingInterventionalPhase 3

A Phase III Study of Paclitaxel/Carboplatin Alone or Combined With Either Trastuzumab and Hyaluronidase-oysk (HERCEPTIN HYLECTA) or Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf (PHESGO) in HER2 Positive, Stage I-IV Endometrial Serous Carcinoma or Carcinosarcoma

NCT ID: NCT05256225Sponsor: National Cancer Institute (NCI)Last updated: 2026-06-03

Summary

This phase III trial tests whether adding trastuzumab and hyaluronidase-oysk (Herceptin Hylecta \[TM\]) or pertuzumab, trastuzumab and hyaluronidase-zzxf (Phesgo \[TM\]) to the usual chemotherapy (paclitaxel and carboplatin) works to shrink tumors in patients with HER2 positive endometrial cancer. Trastuzumab and pertuzumab are monoclonal antibodies and forms of targeted therapy that attach to specific molecules (receptors) on the surface of tumor cells, known as HER2 receptors. When trastuzumab or pertuzumab attach to HER2 receptors, the signals that tell the cells to grow are blocked and the tumor cell may be marked for destruction by the body's immune system. Hyaluronidase is an endoglycosidase. It helps to keep pertuzumab and trastuzumab in the body longer, so that these medications will have a greater effect. Hyaluronidase also allows trastuzumab and trastuzumab/pertuzumab to be given by injection under the skin and shortens their administration time compared to trastuzumab or pertuzumab alone. Paclitaxel is a taxane and in a class of medications called antimicrotubule agents. It stops tumor cells from growing and dividing and may kill them. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Giving Herceptin Hylecta or Phesgo in combination with paclitaxel and carboplatin may shrink the tumor and prevent the cancer from coming back in patients with HER2 positive endometrial cancer.

Detailed description

PRIMARY OBJECTIVES: I. To evaluate the efficacy of trastuzumab and hyaluronidase-oysk (HERCEPTIN HYLECTA) and pertuzumab, trastuzumab, and hyaluronidase-zzxf (PHESGO) in combination with paclitaxel/carboplatin in patients with HER2 positive endometrial cancer. SECONDARY OBJECTIVES: I. To evaluate the efficacy of trastuzumab and hyaluronidase-oysk (HERCEPTIN HYLECTA) and pertuzumab, trastuzumab, and hyaluronidase-zzxf (PHESGO) in combination with paclitaxel/carboplatin in patients with HER2 positive endometrial cancer. II. To evaluate the overall response rate (ORR) in patients with measurable disease. III. To evaluate the duration of objective response in patients with measurable disease as assessed by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1. IV. To determine the nature, frequency and degree of toxicity as assessed by Common Terminology Criteria for Adverse Events (CTCAE) version (v.) 5.0 for each treatment arm. V. To compare quality of life (QOL), as measured by Functional Assessment of Cancer Therapy - Endometrial Trial Outcome Index (FACT-En-TOI), in the experimental versus control arms. VI. To compare patient-reported treatment-associated symptoms (diarrhea and rash) as measured with the Patient Reported Outcomes (PRO) - CTCAE, patient-reported fatigue as measured with the Patient Reported Outcomes Measurement Information System (PROMIS)-Fatigue short form, and worry concerning side effects of treatment as measured by the item 'bothered by side effect', in the FACT-En TOI, respectively, in the experimental and control arms. VII. To assess the correlation of HER2 immunohistochemistry (IHC) expression and in situ hybridization (ISH) amplification with clinical outcome and response to HER2 targeted therapies. EXPLORATORY OBJECTIVE: I. To explore time to sustained deterioration in quality of life, as measured by a drop in the FACT-En-TOI by 6 or more points lasting for more than one PRO time point, in the experimental and control arms. OUTLINE: Patients are randomized to 1 of 3 arms. ARM I: Patients receive paclitaxel intravenously (IV) over 3 hours and carboplatin IV over 30-60 minutes on day 1 of each cycle. Cycles repeat every 3 weeks for 6 cycles in the absence of disease progression or unacceptable toxicity. Patients with stable disease (SD) or partial response (PR) who still have measurable disease after completion of cycle 6 may receive 4 additional cycles of this treatment at the discretion of the treating physician. ARM II: Patients receive paclitaxel IV over 3 hours, carboplatin IV over 30-60 minutes, and trastuzumab/hyaluronidase-oysk subcutaneously (SC) over 2-5 minutes on day 1 of each cycle. Cycles repeat every 3 weeks for 6 cycles in the absence of disease progression or unacceptable toxicity. Patients with SD or PR who still have measurable disease after completion of cycle 6 may receive 4 additional cycles of this treatment at the discretion of the treating physician. MAINTENANCE: Patients receive trastuzumab/hyaluronidase-oysk SC over 2-5 minutes on day 1 of each cycle. Cycles repeat every 3 weeks for up to 1 year in the absence of disease progression or unacceptable toxicity. Patients with SD or PR may continue maintenance therapy for up to 3 years from the start of treatment. ARM III: Patients receive paclitaxel IV over 3 hours, carboplatin IV over 30-60 minutes, and pertuzumab/trastuzumab/hyaluronidase-zzxf SC over 5-8 minutes on day 1 of each cycle. Cycles repeat every 3 weeks for 6 cycles in the absence of disease progression or unacceptable toxicity. Patients with SD or PR who still have measurable disease after completion of cycle 6 may receive 4 additional cycles of this treatment at the discretion of the treating physician. MAINTENANCE: Patients receive pertuzumab/trastuzumab/ hyaluronidase-zzxf SC over 5 minutes on day 1 of each cycle. Cycles repeat every 3 weeks for up to 1 year in absence of disease progression or unacceptable toxicity. Patients with SD or PR may continue maintenance for up to 3 years from the start of treatment. Patients undergo echocardiography (ECHO) or multigated acquisition scan (MUGA) and computed tomography (CT) throughout the study. Additionally, patients may optionally undergo blood sample collection throughout the study, vaginal brachytherapy on study, and urine sample collection prior to treatment. After completion of study treatment, patients are followed up every 3 months for 2 years and then every 6 months for 3 years.

Arms & interventions

  • ProcedureBiospecimen Collection

    Undergo blood and urine sample collection

  • DrugCarboplatin

    Given IV

  • ProcedureComputed Tomography

    Undergo CT

  • ProcedureEchocardiography Test

    Undergo ECHO

  • RadiationHigh-Dose-Rate Vaginal Cuff Brachytherapy

    Undergo vaginal brachytherapy

  • DrugHyaluronidase-zzxf/Pertuzumab/Trastuzumab

    Given SC

  • ProcedureMultigated Acquisition Scan

    Undergo MUGA

  • DrugPaclitaxel

    Given IV

  • OtherSurvey Administration

    Ancillary studies

  • DrugTrastuzumab/Hyaluronidase-oysk

    Given SC

Outcome measures

Primary

  • Progression free survival

    At the end of Phase 2 analysis, if both experimental arms demonstrate superiority to the reference, the experimental arms will be compared to each other.

    Time frame: From study entry to time of progression or death, whichever occurs first, or date of last contact if neither progression nor death has occurred, assessed up to 5 years from randomization

  • Overall survival

    If both experimental arms demonstrate superiority to the reference arm, the experimental arms will be compared to each other.

    Time frame: From study entry to time of death or the date of last contact, assessed up to 5 years from randomization

  • Incidence of dose limiting toxicities

    A dose limiting toxicity is any treatment-related adverse event requiring permanent discontinuation of the experimental therapy prior to the completion of treatment cycle 3.

    Time frame: Up to end of cycle 3 (week 12)

Secondary

  • Objective response rate (ORR)

    Time frame: Within 12 months of initiating maintenance therapy

  • Duration of objective response

    Time frame: From documentation of either PR or CR until disease progression or death, whichever is observed first, assessed up to 5 years from randomization

  • Incidence of adverse events (AEs)

    Time frame: Up to 5 years from randomization

  • HER2 expression

    Time frame: Up to 5 years from randomization

  • Quality of life (QoL)

    Time frame: Up to 5 years from randomization

Eligibility criteria

Sex: FemaleAge: 18 Years and olderHealthy volunteers: No
Inclusion Criteria: * Federation of Gynecology and Obstetrics (FIGO) 2009 stage IA-IVB, non-recurrent, chemotherapy (chemo)-naive, HER2-positive endometrial cancer. The following endometrial cancer types are eligible: * Serous * Other endometrial cancers (including clear cell, endometrioid, mixed epithelial, dedifferentiated/undifferentiated) * Carcinosarcoma * NOTE: Endometrial cancers that are mismatch repair deficient (dMMR) by IHC are not eligible * Histologic confirmation of the original primary tumor is required. Submission of surgical pathology report (or endometrial biopsy pathology report in patients who never undergo hysterectomy) is required * Patients must be within 8 weeks of primary surgery (or endometrial biopsy in patients who never undergo hysterectomy) at the time of study registration * Patients may have measurable disease, non-measurable disease, or no measurable disease. In patients with measurable disease, lesions will be defined and monitored by RECIST v 1.1. Measurable disease is defined as at least one lesion that can be accurately measured in at least one dimension (longest diameter to be recorded). Each lesion must be \>= 10 mm when measured by CT or magnetic resonance imaging (MRI). Lymph nodes must be \>= 15 mm in short axis when measured by CT or MRI * For patients with uterine-confined (stage I) disease, the tumor must be invasive into the myometrium. Any amount of myoinvasion is acceptable for eligibility. Patients with non-invasive disease, endometrial intraepithelial carcinoma alone, or disease confined to a polyp will be excluded * All patients must have tumors that are HER2 positive as defined by American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) 2018 Breast Cancer guidelines. IHC and ISH testing will be done locally, at each participating institution and interpreted by local pathologists. In general HER2 positivity is defined as any of the following: * 3+ immunohistochemistry (IHC), * 2+ IHC with positive in situ hybridization (ISH) Alternatively, patients could be eligible if next generation sequencing (NGS) demonstrates HER2 (ERBB2) amplification. NGS testing can be performed through any designated labs as per the National Cancer Institute (NCI) MATCH/NCI Combo-MATCH trial. Pathology report showing results of institutional HER2 testing (or NGS testing results) must be submitted. Sites must submit all results available (IHC, ISH, and NGS) * Eastern Cooperative Oncology Group (ECOG) performance status of 0, 1 or 2 * Age \>= 18 * Platelets \>= 100,000/mcl (within 14 days prior to registration) * Absolute neutrophil count (ANC) \>= 1,500/mcl (within 14 days prior to registration) * Creatinine =\< 1.5 x institutional/laboratory upper limit of normal (ULN) or estimated Glomerular filtration rate (eGFR) \>= 50 mL/min using either the Cockcroft-Gault equation, the Modification of Diet in Renal Disease Study, or as reported in the comprehensive metabolic panel/basic metabolic panel (eGFR) (within 14 days prior to registration) * Total serum bilirubin level =\< 1.5 x ULN (patients with known Gilbert's disease who have bilirubin level =\< 3 x ULN may be enrolled) (within 14 days prior to registration) * Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =\< 3 x ULN (within 14 days prior to registration) * Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months of registration are eligible for this trial * Although the uterus will have been removed in the vast majority of patients, for patients of child-bearing potential: negative urine or serum pregnancy test. If the urine test is positive or cannot be confirmed as negative, a serum pregnancy test is required. Patients will be considered of non-reproductive potential if they are either: * Postmenopausal (defined as at least 12 months with no menses without an alternative medical cause; in women \< 45 years of age, a high follicle stimulating hormone \[FSH\] level in the postmenopausal range may be used to confirm a postmenopausal state in women not using hormonal contraception or hormonal replacement therapy. In the absence of 12 months of amenorrhea, a single FSH measurement is insufficient); OR * Have had a hysterectomy and/or bilateral oophorectomy, bilateral salpingectomy or bilateral tubal ligation/occlusion at least 6 weeks prior to registration * Have a congenital or acquired condition that prevents childbearing * Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial * Patients with evidence of chronic hepatitis B virus (HBV) infection must have an undetectable HBV viral load on suppressive therapy, if indicated * Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load * Patients with treated brain metastases are eligible if follow-up brain imaging after central nervous system (CNS)-directed therapy shows no evidence of progression * The patient or a legally authorized representative must provide study-specific informed consent prior to study entry and, for patients treated in the United States (U.S.), authorization permitting release of personal health information Exclusion Criteria: * Prior Therapy: * Patients must NOT have received prior chemotherapy, biologic therapy, or targeted therapy for treatment of endometrial carcinoma * Patients must NOT have received prior radiation therapy for treatment of endometrial carcinoma. Prior radiation includes external beam pelvic radiation therapy, external beam extended field pelvic/para-aortic radiation therapy, and/or intravaginal brachytherapy * NOTE: Vaginal brachytherapy for treatment of endometrial cancer is permitted during study treatment. Planned use of vaginal brachytherapy must be declared at time of registration * Patients may have received prior hormonal therapy for treatment of endometrial carcinoma. All hormonal therapy must be discontinued at least one week prior to registration * Patients may not have a planned interval cytoreduction or hysterectomy, prior to documentation of progression, after study registration * Patients may not have planned external beam radiotherapy, prior to documentation of progression, after study registration * Significant cardiovascular disease including: * Uncontrolled hypertension, defined as systolic \> 150 mm Hg or diastolic \> 90 mm Hg despite antihypertensive medications * Myocardial infarction or unstable angina within 6 months prior to registration * New York Heart Association functional classification II, III or IV * Serious cardiac arrhythmia requiring medication. This does not include asymptomatic, atrial fibrillation with controlled ventricular rate * Significant lung disease: dyspnea at rest grade 2 or greater (resulting from extensive tumor involvement or other causes), pneumonitis grade 2 or greater, interstitial lung disease grade 2 or greater, idiopathic pulmonary fibrosis, cystic fibrosis, Aspergillosis, active tuberculosis, or history of opportunistic infections (pneumocystis pneumonia or cytomegalovirus pneumonia) * Patients with uncontrolled intercurrent illness including, but not limited to: ongoing or active infection (except for uncomplicated urinary tract infection), uncontrolled interstitial lung disease, symptomatic congestive heart failure, or psychiatric illness/social situations that would limit compliance with study requirements * Treatment with strong CYP2C8 or CYP3A4 inhibitors or inducers within 14 days or 5 drug-elimination half-lives, whichever is longer, prior to registration * Women who are unwilling to discontinue nursing

Study locations (403)

University of Alabama at Birmingham Cancer Center

Birmingham, Alabama, 35233

Recruiting
Site Public Contact · Contact
gingerreeves@uabmc.edu
Michael D. Toboni · Principal Investigator

Alaska Women's Cancer Care

Anchorage, Alaska, 99508

Recruiting
Site Public Contact · Contact
907-212-6871AKPAMC.OncologyResearchSupport@providence.org
Dan S. Zuckerman · Principal Investigator

Banner University Medical Center - Tucson

Tucson, Arizona, 85719

Recruiting
Site Public Contact · Contact
UACC-IIT@uacc.arizona.edu
Setsuko K. Chambers · Principal Investigator

University of Arizona Cancer Center-North Campus

Tucson, Arizona, 85719

Recruiting
Site Public Contact · Contact
UACC-IIT@uacc.arizona.edu
Setsuko K. Chambers · Principal Investigator

University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72205

Recruiting
Site Public Contact · Contact
501-686-8274
Heather R. Williams · Principal Investigator

Sutter Auburn Faith Hospital

Auburn, California, 95602

Recruiting
Site Public Contact · Contact
clinicalresearch@sutterhealth.org
John K. Chan · Principal Investigator

Alta Bates Summit Medical Center-Herrick Campus

Berkeley, California, 94704

Suspended

John Muir Medical Center-Concord

Concord, California, 94520

Active Not Recruiting

City of Hope Comprehensive Cancer Center

Duarte, California, 91010

Active Not Recruiting

City of Hope Seacliff

Huntington Beach, California, 92648

Active Not Recruiting

UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care

Irvine, California, 92612

Recruiting
Site Public Contact · Contact
877-827-8839ucstudy@uci.edu
Krishnansu S. Tewari · Principal Investigator

City of Hope at Irvine Lennar

Irvine, California, 92618

Active Not Recruiting

Kaiser Permanente-Irvine

Irvine, California, 92618

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Scott E. Lentz · Principal Investigator

City of Hope at Long Beach Elm

Long Beach, California, 90813

Active Not Recruiting

Kaiser Permanente Los Angeles Medical Center

Los Angeles, California, 90027

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Scott E. Lentz · Principal Investigator

Memorial Medical Center

Modesto, California, 95355

Recruiting
Site Public Contact · Contact
clinicalresearch@sutterhealth.org
John K. Chan · Principal Investigator

Palo Alto Medical Foundation-Gynecologic Oncology

Mountain View, California, 94040

Suspended

Saint Joseph Hospital - Orange

Orange, California, 92868

Recruiting
Site Public Contact · Contact
714-734-6220
Madhavi Mummaneni · Principal Investigator

UC Irvine Health/Chao Family Comprehensive Cancer Center

Orange, California, 92868

Recruiting
Site Public Contact · Contact
877-827-8839ucstudy@uci.edu
Krishnansu S. Tewari · Principal Investigator

Stanford Cancer Institute Palo Alto

Palo Alto, California, 94304

Recruiting
Site Public Contact · Contact
650-498-7061ccto-office@stanford.edu
Kristin L. Bixel · Principal Investigator

Kaiser Permanente - Panorama City

Panorama City, California, 91402

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Scott E. Lentz · Principal Investigator

Kaiser Permanente-Riverside

Riverside, California, 92505

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Scott E. Lentz · Principal Investigator

Sutter Roseville Medical Center

Roseville, California, 95661

Recruiting
Site Public Contact · Contact
clinicalresearch@sutterhealth.org
John K. Chan · Principal Investigator

Sutter Medical Center Sacramento

Sacramento, California, 95816

Recruiting
Site Public Contact · Contact
clinicalresearch@sutterhealth.org
John K. Chan · Principal Investigator

University of California Davis Comprehensive Cancer Center

Sacramento, California, 95817

Recruiting
Site Public Contact · Contact
916-734-3089
Rebecca A. Brooks · Principal Investigator

California Pacific Medical Center-Pacific Campus

San Francisco, California, 94115

Recruiting
Site Public Contact · Contact
clinicalresearch@sutterhealth.org
John K. Chan · Principal Investigator

Palo Alto Medical Foundation-Santa Cruz

Santa Cruz, California, 95065

Recruiting
Site Public Contact · Contact
clinicalresearch@sutterhealth.org
John K. Chan · Principal Investigator

Palo Alto Medical Foundation-Sunnyvale

Sunnyvale, California, 94086

Recruiting
Site Public Contact · Contact
clinicalresearch@sutterhealth.org
John K. Chan · Principal Investigator

City of Hope Upland

Upland, California, 91786

Active Not Recruiting

John Muir Medical Center-Walnut Creek

Walnut Creek, California, 94598

Recruiting
Site Public Contact · Contact
925-941-4246clinicalresearch@johnmuirhealth.com
Babak Edraki · Principal Investigator

UCHealth University of Colorado Hospital

Aurora, Colorado, 80045

Recruiting
Site Public Contact · Contact
720-848-0650
Marisa R. Moroney · Principal Investigator

UCHealth - Cherry Creek

Denver, Colorado, 80206

Recruiting
Site Public Contact · Contact
412-339-5294Roster@nrgoncology.org
Marisa R. Moroney · Principal Investigator

AdventHealth Porter

Denver, Colorado, 80210

Recruiting
Site Public Contact · Contact
research.institute@adventhealth.com
Neil T. Phippen · Principal Investigator

Grand Valley Oncology

Grand Junction, Colorado, 81505

Suspended

Banner North Colorado Medical Center

Greeley, Colorado, 80631

Recruiting
Site Public Contact · Contact
970-810-3046BMDACCResearchCOMailbox@bannerhealth.com
Robin A. Lacour · Principal Investigator

UCHealth Highlands Ranch Hospital

Highlands Ranch, Colorado, 80129

Recruiting
Site Public Contact · Contact
720-848-0650
Marisa R. Moroney · Principal Investigator

Banner North Colorado Medical Center - Loveland Campus

Loveland, Colorado, 80539

Recruiting
Site Public Contact · Contact
970-810-3046BMDACCResearchCOMailbox@bannerhealth.com
Robin A. Lacour · Principal Investigator

Danbury Hospital

Danbury, Connecticut, 06810

Recruiting
Site Public Contact · Contact
203-739-8074
Wenli Gao · Principal Investigator

Smilow Cancer Hospital-Derby Care Center

Derby, Connecticut, 06418

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Alessandro D. Santin · Principal Investigator

Smilow Cancer Hospital Care Center-Fairfield

Fairfield, Connecticut, 06824

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Alessandro D. Santin · Principal Investigator

Smilow Cancer Hospital Care Center at Glastonbury

Glastonbury, Connecticut, 06033

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Alessandro D. Santin · Principal Investigator

Smilow Cancer Hospital Care Center at Greenwich

Greenwich, Connecticut, 06830

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Alessandro D. Santin · Principal Investigator

Smilow Cancer Hospital Care Center - Guilford

Guilford, Connecticut, 06437

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Alessandro D. Santin · Principal Investigator

Smilow Cancer Hospital Care Center at Saint Francis

Hartford, Connecticut, 06105

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Alessandro D. Santin · Principal Investigator

Yale University

New Haven, Connecticut, 06520

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Alessandro D. Santin · Principal Investigator

Yale-New Haven Hospital North Haven Medical Center

North Haven, Connecticut, 06473

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Alessandro D. Santin · Principal Investigator

Norwalk Hospital

Norwalk, Connecticut, 06856

Recruiting
Site Public Contact · Contact
203-852-2996jennifer.long@norwalkhealth.org
Richard C. Frank · Principal Investigator

Smilow Cancer Hospital Care Center at Long Ridge

Stamford, Connecticut, 06902

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Alessandro D. Santin · Principal Investigator

Smilow Cancer Hospital-Torrington Care Center

Torrington, Connecticut, 06790

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Alessandro D. Santin · Principal Investigator

Smilow Cancer Hospital Care Center-Trumbull

Trumbull, Connecticut, 06611

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Alessandro D. Santin · Principal Investigator

Smilow Cancer Hospital-Waterbury Care Center

Waterbury, Connecticut, 06708

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Alessandro D. Santin · Principal Investigator

Smilow Cancer Hospital Care Center - Waterford

Waterford, Connecticut, 06385

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Alessandro D. Santin · Principal Investigator

Helen F Graham Cancer Center

Newark, Delaware, 19713

Recruiting
Site Public Contact · Contact
302-623-4450lbarone@christianacare.org
Gregory A. Masters · Principal Investigator

Medical Oncology Hematology Consultants PA

Newark, Delaware, 19713

Recruiting
Site Public Contact · Contact
302-623-4450lbarone@christianacare.org
Gregory A. Masters · Principal Investigator

Sibley Memorial Hospital

Washington D.C., District of Columbia, 20016

Recruiting
Site Public Contact · Contact
202-243-2373jquiver1@jhmi.edu
Amanda N. Fader · Principal Investigator

George Washington University Medical Center

Washington D.C., District of Columbia, 20037

Recruiting
Site Public Contact · Contact
202-741-2210
Micael Lopez Acevedo · Principal Investigator

Broward Health Medical Center

Fort Lauderdale, Florida, 33316

Recruiting
Site Public Contact · Contact
302-651-5572Allison.bruce@nemours.org
Scott E. Jordan · Principal Investigator

Jupiter Medical Center

Jupiter, Florida, 33458

Active Not Recruiting

Sarasota Memorial Hospital-Venice

N. Venice, Florida, 34275

Recruiting
Site Public Contact · Contact
941-261-9000
Beverly Long · Principal Investigator

AdventHealth Orlando

Orlando, Florida, 32803

Recruiting
Site Public Contact · Contact
407-303-2090FH.Cancer.Research@flhosp.org
Nathalie D. McKenzie · Principal Investigator

Florida Cancer Specialists - Sarasota Downtown

Sarasota, Florida, 34236

Recruiting
Site Public Contact · Contact
941-957-1000
Beverly Long · Principal Investigator

First Physicians Group-Sarasota

Sarasota, Florida, 34239

Recruiting
Site Public Contact · Contact
941-917-8383
Beverly Long · Principal Investigator

Sarasota Memorial Hospital

Sarasota, Florida, 34239

Recruiting
Site Public Contact · Contact
941-917-2225
Beverly Long · Principal Investigator

Florida Cancer Specialists - Venice Pinebrook

Venice, Florida, 34275

Recruiting
Site Public Contact · Contact
239-274-9930ClinicalTrials@FLCancer.com
Beverly Long · Principal Investigator

Grady Health System

Atlanta, Georgia, 30303

Recruiting
Site Public Contact · Contact
404-778-1868
Namita Khanna · Principal Investigator

Emory University Hospital Midtown

Atlanta, Georgia, 30308

Recruiting
Site Public Contact · Contact
888-946-7447
Namita Khanna · Principal Investigator

Piedmont Hospital

Atlanta, Georgia, 30309

Recruiting
Site Public Contact · Contact
404-425-7943ORS@piedmont.org
Leda Portia A. Gattoc · Principal Investigator

Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia, 30322

Recruiting
Site Public Contact · Contact
404-778-1868
Namita Khanna · Principal Investigator

Emory Saint Joseph's Hospital

Atlanta, Georgia, 30342

Recruiting
Site Public Contact · Contact
404-851-7115
Namita Khanna · Principal Investigator

Augusta University Medical Center

Augusta, Georgia, 30912

Recruiting
Site Public Contact · Contact
706-721-2388ga_cares@augusta.edu
Sharad A. Ghamande · Principal Investigator

Emory Decatur Hospital

Decatur, Georgia, 30033

Recruiting
Site Public Contact · Contact
440-778-1868clinicaltrialsoncology@dekalbmedical.org
Namita Khanna · Principal Investigator

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

Savannah, Georgia, 31405

Recruiting
Site Public Contact · Contact
912-819-5704underberga@sjchs.org
Sarah E. Gill · Principal Investigator

Queen's Medical Center

Honolulu, Hawaii, 96813

Suspended

Kapiolani Medical Center for Women and Children

Honolulu, Hawaii, 96826

Suspended

Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706

Recruiting
Site Public Contact · Contact
734-712-3671stephanie.couch@stjoeshealth.org
J. R. Liu · Principal Investigator

Saint Luke's Cancer Institute - Boise

Boise, Idaho, 83712

Recruiting
Site Public Contact · Contact
208-381-2774eslinget@slhs.org
Dan S. Zuckerman · Principal Investigator

Saint Alphonsus Cancer Care Center-Caldwell

Caldwell, Idaho, 83605

Recruiting
Site Public Contact · Contact
734-712-3671stephanie.couch@stjoeshealth.org
J. R. Liu · Principal Investigator

Kootenai Health - Coeur d'Alene

Coeur d'Alene, Idaho, 83814

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Saint Luke's Cancer Institute - Fruitland

Fruitland, Idaho, 83619

Recruiting
Site Public Contact · Contact
208-381-2774eslinget@slhs.org
Dan S. Zuckerman · Principal Investigator

Saint Luke's Cancer Institute - Meridian

Meridian, Idaho, 83642

Recruiting
Site Public Contact · Contact
208-381-2774eslinget@slhs.org
Dan S. Zuckerman · Principal Investigator

Saint Alphonsus Cancer Care Center-Nampa

Nampa, Idaho, 83687

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
J. R. Liu · Principal Investigator

Saint Luke's Cancer Institute - Nampa

Nampa, Idaho, 83687

Recruiting
Site Public Contact · Contact
208-381-2774eslinget@slhs.org
Dan S. Zuckerman · Principal Investigator

Kootenai Clinic Cancer Services - Post Falls

Post Falls, Idaho, 83854

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Kootenai Clinic Cancer Services - Sandpoint

Sandpoint, Idaho, 83864

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Saint Luke's Cancer Institute - Twin Falls

Twin Falls, Idaho, 83301

Recruiting
Site Public Contact · Contact
208-381-2774eslinget@slhs.org
Dan S. Zuckerman · Principal Investigator

Northwest Community Hospital

Arlington Heights, Illinois, 60005

Recruiting
Site Public Contact · Contact
847-618-4968
Kathryn A. Mills · Principal Investigator

Rush-Copley Medical Center

Aurora, Illinois, 60504

Recruiting
Site Public Contact · Contact
630-978-6212RCMC_Cancer_Research@rush.edu
Pratima Chalasani · Principal Investigator

Centralia Oncology Clinic

Centralia, Illinois, 62801

Recruiting
Site Public Contact · Contact
217-876-4762morganthaler.jodi@mhsil.com
Bryan A. Faller · Principal Investigator

Northwestern University

Chicago, Illinois, 60611

Recruiting
Site Public Contact · Contact
312-695-1301cancer@northwestern.edu
Emily Hinchcliff · Principal Investigator

John H Stroger Jr Hospital of Cook County

Chicago, Illinois, 60612

Recruiting
Site Public Contact · Contact
312-864-5204
Deimante M. Tamkus · Principal Investigator

Rush MD Anderson Cancer Center

Chicago, Illinois, 60612

Active Not Recruiting

University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637

Recruiting
Site Public Contact · Contact
773-702-8222cancerclinicaltrials@bsd.uchicago.edu
Katherine C. Kurnit · Principal Investigator

Carle at The Riverfront

Danville, Illinois, 61832

Recruiting
Site Public Contact · Contact
800-446-5532Research@Carle.com
Pratima Chalasani · Principal Investigator

Cancer Care Specialists of Illinois - Decatur

Decatur, Illinois, 62526

Recruiting
Site Public Contact · Contact
217-876-4762morganthaler.jodi@mhsil.com
Bryan A. Faller · Principal Investigator

Decatur Memorial Hospital

Decatur, Illinois, 62526

Recruiting
Site Public Contact · Contact
217-876-4762morganthaler.jodi@mhsil.com
Bryan A. Faller · Principal Investigator

Northwestern Medicine Cancer Center Kishwaukee

DeKalb, Illinois, 60115

Recruiting
Site Public Contact · Contact
630-352-5360Donald.Smith3@nm.org
Emily Hinchcliff · Principal Investigator

Carle Physician Group-Effingham

Effingham, Illinois, 62401

Recruiting
Site Public Contact · Contact
800-446-5532Research@carle.com
Pratima Chalasani · Principal Investigator

Crossroads Cancer Center

Effingham, Illinois, 62401

Recruiting
Site Public Contact · Contact
217-876-4762morganthaler.jodi@mhsil.com
Bryan A. Faller · Principal Investigator

NorthShore University HealthSystem-Evanston Hospital

Evanston, Illinois, 60201

Recruiting
Site Public Contact · Contact
847-570-2109
Mary T. Jenkins Vogel · Principal Investigator

Northwestern Medicine Cancer Center Delnor

Geneva, Illinois, 60134

Recruiting
Site Public Contact · Contact
630-352-5360Donald.Smith3@nm.org
Emily Hinchcliff · Principal Investigator

NorthShore University HealthSystem-Glenbrook Hospital

Glenview, Illinois, 60026

Recruiting
Site Public Contact · Contact
847-570-2109
Mary T. Jenkins Vogel · Principal Investigator

Northwestern Medicine Glenview Outpatient Center

Glenview, Illinois, 60026

Active Not Recruiting

Northwestern Medicine Grayslake Outpatient Center

Grayslake, Illinois, 60030

Active Not Recruiting

Ingalls Memorial Hospital

Harvey, Illinois, 60426

Recruiting
Site Public Contact · Contact
708-915-4673clinicaltrials@ingalls.org
Ivy Abraham · Principal Investigator

NorthShore University HealthSystem-Highland Park Hospital

Highland Park, Illinois, 60035

Recruiting
Site Public Contact · Contact
847-570-2109
Mary T. Jenkins Vogel · Principal Investigator

Sudarshan K Sharma MD Limited-Gynecologic Oncology

Hinsdale, Illinois, 60521

Active Not Recruiting

Northwestern Medicine Lake Forest Hospital

Lake Forest, Illinois, 60045

Recruiting
Site Public Contact · Contact
cancertrials@northwestern.edu
Emily Hinchcliff · Principal Investigator

Carle Physician Group-Mattoon/Charleston

Mattoon, Illinois, 61938

Recruiting
Site Public Contact · Contact
800-446-5532Research@carle.com
Pratima Chalasani · Principal Investigator

UC Comprehensive Cancer Center at Silver Cross

New Lenox, Illinois, 60451

Recruiting
Site Public Contact · Contact
773-702-8222cancerclinicaltrials@bsd.uchicago.edu
Katherine C. Kurnit · Principal Investigator

Carle Cancer Institute Normal

Normal, Illinois, 61761

Recruiting
Site Public Contact · Contact
800-446-5532Research@Carle.com
Pratima Chalasani · Principal Investigator

Cancer Care Center of O'Fallon

O'Fallon, Illinois, 62269

Recruiting
Site Public Contact · Contact
217-876-4762morganthaler.jodi@mhsil.com
Bryan A. Faller · Principal Investigator

Northwestern Medicine Orland Park

Orland Park, Illinois, 60462

Recruiting
Site Public Contact · Contact
nctnprogram_rhlccc@northwestern.edu
Emily Hinchcliff · Principal Investigator

University of Chicago Medicine-Orland Park

Orland Park, Illinois, 60462

Recruiting
Site Public Contact · Contact
773-702-8222cancerclinicaltrials@bsd.uchicago.edu
Katherine C. Kurnit · Principal Investigator

UW Health Carbone Cancer Center Rockford

Rockford, Illinois, 61114

Recruiting
Site Public Contact · Contact
779-696-9378lkline@uwhealth.org
Fahrettin Covut · Principal Investigator

Southern Illinois University School of Medicine

Springfield, Illinois, 62702

Recruiting
Site Public Contact · Contact
217-545-7929
Bryan A. Faller · Principal Investigator

Springfield Clinic

Springfield, Illinois, 62702

Recruiting
Site Public Contact · Contact
800-444-7541
Bryan A. Faller · Principal Investigator

Springfield Memorial Hospital

Springfield, Illinois, 62781

Recruiting
Site Public Contact · Contact
217-528-7541pallante.beth@mhsil.com
Bryan A. Faller · Principal Investigator

Carle Cancer Center

Urbana, Illinois, 61801

Recruiting
Site Public Contact · Contact
800-446-5532Research@carle.com
Pratima Chalasani · Principal Investigator

Northwestern Medicine Cancer Center Warrenville

Warrenville, Illinois, 60555

Recruiting
Site Public Contact · Contact
630-352-5360Donald.Smith3@nm.org
Emily Hinchcliff · Principal Investigator

Rush-Copley Healthcare Center

Yorkville, Illinois, 60560

Recruiting
Site Public Contact · Contact
630-978-6212Cancer.Research@rushcopley.com
Pratima Chalasani · Principal Investigator

IU Health North Hospital

Carmel, Indiana, 46032

Recruiting
Site Public Contact · Contact
317-278-5632iutrials@iu.edu
Jessica E. Parker · Principal Investigator

Northwest Cancer Center - Crown Point

Crown Point, Indiana, 46307

Suspended

UChicago Medicine Northwest Indiana

Crown Point, Indiana, 46307

Recruiting
Site Public Contact · Contact
855-702-8222cancerclinicaltrials@bsd.uchicago.edu
Katherine C. Kurnit · Principal Investigator

Northwest Oncology LLC

Dyer, Indiana, 46311

Suspended

Goshen Center for Cancer Care

Goshen, Indiana, 46526

Recruiting
Site Public Contact · Contact
574-364-2973cccois@goshenhealth.com
Pamela J. Stone · Principal Investigator

Northwest Cancer Center - Hobart

Hobart, Indiana, 46342

Recruiting
Site Public Contact · Contact
219-947-1795
Pratima Chalasani · Principal Investigator

Saint Mary Medical Center

Hobart, Indiana, 46342

Suspended

Indiana University/Melvin and Bren Simon Cancer Center

Indianapolis, Indiana, 46202

Suspended

Franciscan Health Indianapolis

Indianapolis, Indiana, 46237

Suspended

Ascension Saint Vincent Indianapolis Hospital

Indianapolis, Indiana, 46260

Active Not Recruiting

Saint Catherine Hospital

Indianapolis, Indiana, 46312

Suspended

Franciscan Saint Elizabeth Health - Lafayette East

Lafayette, Indiana, 47905

Recruiting
Site Public Contact · Contact
888-823-5923ctsucontact@westat.com
Harsha Ranganath · Principal Investigator

Franciscan Health Mooresville

Mooresville, Indiana, 46158

Suspended

The Community Hospital

Munster, Indiana, 46321

Suspended

Women's Diagnostic Center - Munster

Munster, Indiana, 46321

Suspended

Memorial Hospital of South Bend

South Bend, Indiana, 46601

Recruiting
Site Public Contact · Contact
800-284-7370
LaToya J. Perry · Principal Investigator

Northwest Cancer Center - Valparaiso

Valparaiso, Indiana, 46383

Suspended

Mary Greeley Medical Center

Ames, Iowa, 50010

Recruiting
Site Public Contact · Contact
515-956-4132
Joseph J. Merchant · Principal Investigator

McFarland Clinic - Ames

Ames, Iowa, 50010

Recruiting
Site Public Contact · Contact
515-239-4734ksoder@mcfarlandclinic.com
Joseph J. Merchant · Principal Investigator

McFarland Clinic - Boone

Boone, Iowa, 50036

Suspended

Heartland Oncology and Hematology LLP

Council Bluffs, Iowa, 51503

Suspended

Nebraska Cancer Specialists/Oncology Hematology West PC - MEJ

Council Bluffs, Iowa, 51503

Recruiting
Site Public Contact · Contact
402-354-5892Liza.brandes@nmhs.org
Brent J. Tierney · Principal Investigator

McFarland Clinic - Trinity Cancer Center

Fort Dodge, Iowa, 50501

Recruiting
Site Public Contact · Contact
515-956-4132
Joseph J. Merchant · Principal Investigator

University of Iowa/Holden Comprehensive Cancer Center

Iowa City, Iowa, 52242

Recruiting
Site Public Contact · Contact
800-237-1225
David P. Bender · Principal Investigator

McFarland Clinic - Jefferson

Jefferson, Iowa, 50129

Suspended

McFarland Clinic - Marshalltown

Marshalltown, Iowa, 50158

Recruiting
Site Public Contact · Contact
515-956-4132
Joseph J. Merchant · Principal Investigator

Saint Elizabeth Healthcare Edgewood

Edgewood, Kentucky, 41017

Recruiting
Site Public Contact · Contact
859-301-4730Kristi.Curtsinger@stelizabeth.com
Rachel Bramblet · Principal Investigator

Baptist Health Lexington

Lexington, Kentucky, 40503

Recruiting
Site Public Contact · Contact
859-260-6425
Hope Cottrill · Principal Investigator

Baptist Health Louisville

Louisville, Kentucky, 40207

Suspended

LSU Health Baton Rouge-North Clinic

Baton Rouge, Louisiana, 70805

Recruiting
Site Public Contact · Contact
225-765-7659research@ololrmc.com
Marshall P. Stagg · Principal Investigator

Our Lady of the Lake Physician Group

Baton Rouge, Louisiana, 70808

Recruiting
Site Public Contact · Contact
225-765-7659research@ololrmc.com
Marshall P. Stagg · Principal Investigator

Our Lady of the Lake Medical Oncology

Baton Rouge, Louisiana, 70817

Recruiting
Site Public Contact · Contact
225-765-7659research@ololrmc.com
Marshall P. Stagg · Principal Investigator

Ochsner Hematology Oncology North Shore - Covington (West Region)

Covington, Louisiana, 70433

Recruiting
Site Public Contact · Contact
985-809-5668Cheryl.kesler@ochsner.org
Chad A. Hamilton · Principal Investigator

West Jefferson Medical Center

Marrero, Louisiana, 70072

Recruiting
Site Public Contact · Contact
504-210-3539emede1@lsuhsc.edu
Tara Castellano · Principal Investigator

East Jefferson General Hospital

Metairie, Louisiana, 70006

Recruiting
Site Public Contact · Contact
504-210-3539emede1@lsuhsc.edu
Tara Castellano · Principal Investigator

LSU Healthcare Network / Metairie Multi-Specialty Clinic

Metairie, Louisiana, 70006

Recruiting
Site Public Contact · Contact
504-210-3539emede1@lsuhsc.edu
Tara Castellano · Principal Investigator

University Medical Center New Orleans

New Orleans, Louisiana, 70112

Recruiting
Site Public Contact · Contact
504-210-3539emede1@lsuhsc.edu
Tara Castellano · Principal Investigator

Ochsner Baptist Medical Center

New Orleans, Louisiana, 70115

Recruiting
Site Public Contact · Contact
504-842-8084Elisemarie.curry@ochsner.org
Chad A. Hamilton · Principal Investigator

Ochsner Medical Center Jefferson

New Orleans, Louisiana, 70121

Recruiting
Site Public Contact · Contact
504-842-8084Elisemarie.curry@ochsner.org
Chad A. Hamilton · Principal Investigator

Harold Alfond Center for Cancer Care

Augusta, Maine, 04330

Recruiting
Site Public Contact · Contact
207-626-4855
Leslie S. Bradford · Principal Investigator

MaineHealth Maine Medical Center- Scarborough

Scarborough, Maine, 04074

Recruiting
Site Public Contact · Contact
207-396-8670clinicalresearch@mainehealth.org
Leslie S. Bradford · Principal Investigator

Greater Baltimore Medical Center

Baltimore, Maryland, 21204

Suspended

Sinai Hospital of Baltimore

Baltimore, Maryland, 21215

Recruiting
Site Public Contact · Contact
410-601-9083
Pallavi P. Kumar · Principal Investigator

MedStar Franklin Square Medical Center/Weinberg Cancer Institute

Baltimore, Maryland, 21237

Suspended

Johns Hopkins University/Sidney Kimmel Cancer Center

Baltimore, Maryland, 21287

Recruiting
Site Public Contact · Contact
410-955-8804jhcccro@jhmi.edu
Amanda N. Fader · Principal Investigator

Walter Reed National Military Medical Center

Bethesda, Maryland, 20889-5600

Recruiting
Site Public Contact · Contact
301-319-2100
Christopher Tarney · Principal Investigator

William E Kahlert Regional Cancer Center/Sinai Hospital

Westminster, Maryland, 21157

Recruiting
Site Public Contact · Contact
410-871-6400
Pallavi P. Kumar · Principal Investigator

Baystate Medical Center

Springfield, Massachusetts, 01199

Recruiting
Site Public Contact · Contact
413-794-3565tamara.wrenn@baystatehealth.org
Tashanna K. Myers · Principal Investigator

University of Michigan Rogel Cancer Center

Ann Arbor, Michigan, 48109

Recruiting
Site Public Contact · Contact
800-865-1125CancerAnswerLine@med.umich.edu
Zhen Ni Zhou · Principal Investigator

Bronson Battle Creek

Battle Creek, Michigan, 49017

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Trinity Health IHA Medical Group Hematology Oncology - Brighton

Brighton, Michigan, 48114

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
J. R. Liu · Principal Investigator

Trinity Health IHA Medical Group Hematology Oncology - Canton

Canton, Michigan, 48188

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
J. R. Liu · Principal Investigator

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital

Chelsea, Michigan, 48118

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
J. R. Liu · Principal Investigator

Wayne State University/Karmanos Cancer Institute

Detroit, Michigan, 48201

Active Not Recruiting

Weisberg Cancer Treatment Center

Farmington Hills, Michigan, 48334

Active Not Recruiting

Corewell Health Farmington Hills Hospital

Farmington Hills, Michigan, 48336

Active Not Recruiting

Cancer Hematology Centers - Flint

Flint, Michigan, 48503

Recruiting
Site Public Contact · Contact
810-762-8038wstrong@ghci.org
J. R. Liu · Principal Investigator

Genesee Hematology Oncology PC

Flint, Michigan, 48503

Suspended

Genesys Hurley Cancer Institute

Flint, Michigan, 48503

Recruiting
Site Public Contact · Contact
810-762-8038wstrong@ghci.org
J. R. Liu · Principal Investigator

Hurley Medical Center

Flint, Michigan, 48503

Recruiting
Site Public Contact · Contact
810-762-8038wstrong@ghci.org
J. R. Liu · Principal Investigator

Corewell Health Grand Rapids Hospitals - Butterworth Hospital

Grand Rapids, Michigan, 49503

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Trinity Health Grand Rapids Hospital

Grand Rapids, Michigan, 49503

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Bronson Methodist Hospital

Kalamazoo, Michigan, 49007

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

West Michigan Cancer Center

Kalamazoo, Michigan, 49007

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Beacon Kalamazoo Cancer Center

Kalamazoo, Michigan, 49009

Recruiting
Site Public Contact · Contact
574-647-7370
Kathleen Y. Butler · Principal Investigator

Trinity Health Saint Mary Mercy Livonia Hospital

Livonia, Michigan, 48154

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
J. R. Liu · Principal Investigator

Trinity Health Muskegon Hospital

Muskegon, Michigan, 49444

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Corewell Health Lakeland Hospitals - Niles Hospital

Niles, Michigan, 49120

Recruiting
Site Public Contact · Contact
616-391-1230
Kathleen Y. Butler · Principal Investigator

Cancer and Hematology Centers of Western Michigan - Norton Shores

Norton Shores, Michigan, 49444

Recruiting
Site Public Contact · Contact
616-391-1230connie.szczepanek@crcwm.org
Kathleen Y. Butler · Principal Investigator

Trinity Health Saint Joseph Mercy Oakland Hospital

Pontiac, Michigan, 48341

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
J. R. Liu · Principal Investigator

Corewell Health Reed City Hospital

Reed City, Michigan, 49677

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Corewell Health William Beaumont University Hospital

Royal Oak, Michigan, 48073

Active Not Recruiting

MyMichigan Medical Center Saginaw

Saginaw, Michigan, 48601

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
J. R. Liu · Principal Investigator

Oncology Hematology Associates of Saginaw Valley PC

Saginaw, Michigan, 48604

Suspended

Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center

Saint Joseph, Michigan, 49085

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Corewell Health Lakeland Hospitals - Saint Joseph Hospital

Saint Joseph, Michigan, 49085

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

MyMichigan Medical Center Tawas

Tawas City, Michigan, 48764

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
J. R. Liu · Principal Investigator

Munson Medical Center

Traverse City, Michigan, 49684

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Corewell Health Beaumont Troy Hospital

Troy, Michigan, 48085

Active Not Recruiting

Saint Mary's Oncology/Hematology Associates of West Branch

West Branch, Michigan, 48661

Suspended

University of Michigan Health - West

Wyoming, Michigan, 49519

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus

Ypsilanti, Michigan, 48197

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
J. R. Liu · Principal Investigator

Mercy Hospital

Coon Rapids, Minnesota, 55433

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Jessica A. Thomes Pepin · Principal Investigator

Fairview Southdale Hospital

Edina, Minnesota, 55435

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Jessica A. Thomes Pepin · Principal Investigator

Minnesota Oncology Hematology PA-Maplewood

Maplewood, Minnesota, 55109

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Jessica A. Thomes Pepin · Principal Investigator

Avera Cancer Institute at Marshall

Marshall, Minnesota, 56258

Recruiting
Site Public Contact · Contact
605-322-3095OncRegulatory@avera.org
David C. Starks · Principal Investigator

Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Jessica A. Thomes Pepin · Principal Investigator

University of Minnesota/Masonic Cancer Center

Minneapolis, Minnesota, 55455

Recruiting
Site Public Contact · Contact
612-624-2620
Britt K. Erickson · Principal Investigator

Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Jessica A. Thomes Pepin · Principal Investigator

Regions Hospital

Saint Paul, Minnesota, 55101

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Jessica A. Thomes Pepin · Principal Investigator

United Hospital

Saint Paul, Minnesota, 55102

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Jessica A. Thomes Pepin · Principal Investigator

Minnesota Oncology Hematology PA-Woodbury

Woodbury, Minnesota, 55125

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Jessica A. Thomes Pepin · Principal Investigator

MU Health - University Hospital/Ellis Fischel Cancer Center

Columbia, Missouri, 65212

Suspended

Phelps Health Delbert Day Cancer Institute

Rolla, Missouri, 65401

Recruiting
Site Public Contact · Contact
573-458-7504research@phelpshealth.org
Jay W. Carlson · Principal Investigator

CoxHealth South Hospital

Springfield, Missouri, 65807

Recruiting
Site Public Contact · Contact
417-269-4520
Jay W. Carlson · Principal Investigator

Washington University School of Medicine

St Louis, Missouri, 63110

Recruiting
Site Public Contact · Contact
800-600-3606info@siteman.wustl.edu
Premal H. Thaker · Principal Investigator

Mercy Hospital South

St Louis, Missouri, 63128

Recruiting
Site Public Contact · Contact
314-525-6042Danielle.Werle@mercy.net
Jay W. Carlson · Principal Investigator

Mercy Hospital Saint Louis

St Louis, Missouri, 63141

Recruiting
Site Public Contact · Contact
314-251-7066
Jay W. Carlson · Principal Investigator

Community Hospital of Anaconda

Anaconda, Montana, 59711

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Billings Clinic Cancer Center

Billings, Montana, 59101

Recruiting
Site Public Contact · Contact
800-996-2663research@billingsclinic.org
John M. Schallenkamp · Principal Investigator

Saint Vincent Frontier Cancer Center

Billings, Montana, 59102

Recruiting
Site Public Contact · Contact
800-648-6274
Patrick W. Cobb · Principal Investigator

Intermountain Health West End Clinic

Billings, Montana, 59106

Recruiting
Site Public Contact · Contact
406-238-6685
Patrick W. Cobb · Principal Investigator

Bozeman Health Deaconess Hospital

Bozeman, Montana, 59715

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Benefis Sletten Cancer Institute

Great Falls, Montana, 59405

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Logan Health Medical Center

Kalispell, Montana, 59901

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Saint Patrick Hospital - Community Hospital

Missoula, Montana, 59802

Recruiting
Site Public Contact · Contact
406-327-3118amy.hanneman@providence.org
Dan S. Zuckerman · Principal Investigator

Community Medical Center

Missoula, Montana, 59804

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Nebraska Cancer Specialists/Oncology Hematology West PC - MECC

Omaha, Nebraska, 68114

Recruiting
Site Public Contact · Contact
402-334-4773
Brent J. Tierney · Principal Investigator

Nebraska Methodist Hospital

Omaha, Nebraska, 68114

Recruiting
Site Public Contact · Contact
402-354-5144
Brent J. Tierney · Principal Investigator

Alegent Health Bergan Mercy Medical Center

Omaha, Nebraska, 68124

Suspended

University of Nebraska Medical Center

Omaha, Nebraska, 68198

Recruiting
Site Public Contact · Contact
402-559-6941unmcrsa@unmc.edu
Kerry J. Rodabaugh · Principal Investigator

OptumCare Cancer Care at Charleston

Las Vegas, Nevada, 89102

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

Women's Cancer Center of Nevada

Las Vegas, Nevada, 89106

Recruiting
Site Public Contact · Contact
702-851-4672
Nicola M. Spirtos · Principal Investigator

OptumCare Cancer Care at Fort Apache

Las Vegas, Nevada, 89183

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, 07920

Recruiting
Site Public Contact · Contact
212-639-7592
Carol Aghajanian · Principal Investigator

Cooper Hospital University Medical Center

Camden, New Jersey, 08103

Recruiting
Site Public Contact · Contact
856-325-6757
David P. Warshal · Principal Investigator

Hackensack University Medical Center

Hackensack, New Jersey, 07601

Recruiting
Site Public Contact · Contact
551-996-2897
Donna M. McNamara · Principal Investigator

Monmouth Medical Center Southern Campus

Lakewood, New Jersey, 08701

Recruiting
Site Public Contact · Contact
732-923-6564mary.danish@rwjbh.org
Eugenia Girda · Principal Investigator

Saint Barnabas Medical Center

Livingston, New Jersey, 07039

Recruiting
Site Public Contact · Contact
973-322-2934joanne.loeb@rwjbh.org
Eugenia Girda · Principal Investigator

Monmouth Medical Center

Long Branch, New Jersey, 07740

Recruiting
Site Public Contact · Contact
732-923-6564mary.danish@rwjbh.org
Eugenia Girda · Principal Investigator

Memorial Sloan Kettering Monmouth

Middletown, New Jersey, 07748

Recruiting
Site Public Contact · Contact
212-639-7592
Carol Aghajanian · Principal Investigator

Memorial Sloan Kettering Bergen

Montvale, New Jersey, 07645

Recruiting
Site Public Contact · Contact
212-639-7592
Carol Aghajanian · Principal Investigator

Virtua Samson Cancer Center

Moorestown, New Jersey, 08057

Active Not Recruiting

Jersey Shore Medical Center

Neptune City, New Jersey, 07753

Recruiting
Site Public Contact · Contact
732-776-4240
Karim S. ElSahwi · Principal Investigator

Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, 08903

Recruiting
Site Public Contact · Contact
732-235-7356
Eugenia Girda · Principal Investigator

Rutgers New Jersey Medical School

Newark, New Jersey, 07101

Recruiting
Site Public Contact · Contact
732-235-7356
Eugenia Girda · Principal Investigator

Riverview Medical Center/Booker Cancer Center

Red Bank, New Jersey, 07701

Recruiting
Site Public Contact · Contact
732-530-2382
Karim S. ElSahwi · Principal Investigator

Sidney Kimmel Cancer Center Washington Township

Sewell, New Jersey, 08080

Recruiting
Site Public Contact · Contact
215-600-9151ONCTrialNow@jefferson.edu
Mitchell I. Edelson · Principal Investigator

Robert Wood Johnson University Hospital Somerset

Somerville, New Jersey, 08876

Recruiting
Site Public Contact · Contact
908-685-2481Siby.Varughese@rwjbh.org
Eugenia Girda · Principal Investigator

Community Medical Center

Toms River, New Jersey, 08755

Recruiting
Site Public Contact · Contact
732-557-8294Lennette.Gonzales@rwjbh.org
Eugenia Girda · Principal Investigator

Virtua Voorhees

Voorhees Township, New Jersey, 08043

Active Not Recruiting

University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106

Recruiting
Site Public Contact · Contact
505-925-0348HSC-ClinicalTrialInfo@salud.unm.edu
Carolyn Y. Muller · Principal Investigator

Presbyterian Kaseman Hospital

Albuquerque, New Mexico, 87110

Active Not Recruiting

Presbyterian Rust Medical Center/Jorgensen Cancer Center

Rio Rancho, New Mexico, 87124

Active Not Recruiting

Women's Cancer Care Associates LLC

Albany, New York, 12208

Recruiting
Site Public Contact · Contact
518-458-1390jbarlin@womenscancercareassociates.com
Peter J. Frederick · Principal Investigator

Memorial Sloan Kettering Commack

Commack, New York, 11725

Recruiting
Site Public Contact · Contact
212-639-7592
Carol Aghajanian · Principal Investigator

Memorial Sloan Kettering Westchester

Harrison, New York, 10604

Recruiting
Site Public Contact · Contact
212-639-7592
Carol Aghajanian · Principal Investigator

NYU Langone Hospital - Long Island

Mineola, New York, 11501

Recruiting
Site Public Contact · Contact
212-263-4432cancertrials@nyulangone.org
Whitfield B. Growdon · Principal Investigator

Mount Sinai Chelsea

New York, New York, 10011

Recruiting
Site Public Contact · Contact
212-824-7309CCTO@mssm.edu
Stephanie V. Blank · Principal Investigator

Laura and Isaac Perlmutter Cancer Center at NYU Langone

New York, New York, 10016

Recruiting
Site Public Contact · Contact
CancerTrials@nyulangone.org
Whitfield B. Growdon · Principal Investigator

Mount Sinai Hospital

New York, New York, 10029

Recruiting
Site Public Contact · Contact
212-824-7309CCTO@mssm.edu
Stephanie V. Blank · Principal Investigator

Memorial Sloan Kettering Cancer Center

New York, New York, 10065

Recruiting
Site Public Contact · Contact
212-639-7592
Carol Aghajanian · Principal Investigator

University of Rochester

Rochester, New York, 14642

Recruiting
Site Public Contact · Contact
585-275-5830
Richard G. Moore · Principal Investigator

State University of New York Upstate Medical University

Syracuse, New York, 13210

Recruiting
Site Public Contact · Contact
315-464-5476
Mary J. Cunningham · Principal Investigator

Memorial Sloan Kettering Nassau

Uniondale, New York, 11553

Recruiting
Site Public Contact · Contact
212-639-7592
Carol Aghajanian · Principal Investigator

Wilmot Cancer Institute at Webster

Webster, New York, 14580

Recruiting
Site Public Contact · Contact
WCICTOresearch@urmc.rochester.edu
Richard G. Moore · Principal Investigator

Duke Cancer Center Cary

Cary, North Carolina, 27518

Recruiting
Site Public Contact · Contact
NCTNStudyTeam@dm.duke.edu
Angeles A. Secord · Principal Investigator

UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, 27599

Recruiting
Site Public Contact · Contact
877-668-0683cancerclinicaltrials@med.unc.edu
Linda Van Le · Principal Investigator

Duke University Medical Center

Durham, North Carolina, 27710

Recruiting
Site Public Contact · Contact
888-275-3853
Angeles A. Secord · Principal Investigator

ECU Health Medical Center

Greenville, North Carolina, 27834

Recruiting
Site Public Contact · Contact
252-744-2391research@ecuhealth.org
Jhalak Dholakia · Principal Investigator

Hayworth Cancer Center

High Point, North Carolina, 27262

Active Not Recruiting

Duke Women's Cancer Care Raleigh

Raleigh, North Carolina, 27607

Recruiting
Site Public Contact · Contact
919-785-4878
Angeles A. Secord · Principal Investigator

Novant Health New Hanover Regional Medical Center

Wilmington, North Carolina, 28401

Recruiting
Site Public Contact · Contact
910-342-3000
Lucybeth Nieves-Arriba · Principal Investigator

Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157

Active Not Recruiting

Sanford Bismarck Medical Center

Bismarck, North Dakota, 58501

Recruiting
Site Public Contact · Contact
701-323-5760OncologyClinicalTrialsFargo@sanfordhealth.org
Maria C. Bell · Principal Investigator

Sanford Broadway Medical Center

Fargo, North Dakota, 58122

Recruiting
Site Public Contact · Contact
701-323-5760OncologyClinicalTrialsFargo@sanfordhealth.org
Maria C. Bell · Principal Investigator

Sanford Roger Maris Cancer Center

Fargo, North Dakota, 58122

Recruiting
Site Public Contact · Contact
701-234-6161OncologyClinicalTrialsFargo@sanfordhealth.org
Maria C. Bell · Principal Investigator

UHHS-Chagrin Highlands Medical Center

Beachwood, Ohio, 44122

Recruiting
Site Public Contact · Contact
800-641-2422CTUReferral@UHhospitals.org
Amy Armstrong · Principal Investigator

Strecker Cancer Center-Belpre

Belpre, Ohio, 45714

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

Aultman Health Foundation

Canton, Ohio, 44710

Recruiting
Site Public Contact · Contact
330-363-7274ClinicalReserachDept@aultman.com
Raza A. Khan · Principal Investigator

Miami Valley Hospital South

Centerville, Ohio, 45459

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Michael S. Guy · Principal Investigator

Geauga Hospital

Chardon, Ohio, 44024

Recruiting
Site Public Contact · Contact
800-641-2422CTUReferral@UHhospitals.org
Amy Armstrong · Principal Investigator

Adena Regional Medical Center

Chillicothe, Ohio, 45601

Recruiting
Site Public Contact · Contact
877-779-7585Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

Good Samaritan Hospital - Cincinnati

Cincinnati, Ohio, 45220

Recruiting
Site Public Contact · Contact
720-874-1881ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Case Western Reserve University

Cleveland, Ohio, 44106

Recruiting
Site Public Contact · Contact
800-641-2422CTUReferral@UHhospitals.org
Amy Armstrong · Principal Investigator

MetroHealth Medical Center

Cleveland, Ohio, 44109

Recruiting
Site Public Contact · Contact
216-778-7559ababal@metrohealth.org
Kimberly E. Resnick · Principal Investigator

Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210

Recruiting
Site Public Contact · Contact
800-293-5066Jamesline@osumc.edu
Casey Cosgrove · Principal Investigator

Mount Carmel East Hospital

Columbus, Ohio, 43213

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

Riverside Methodist Hospital

Columbus, Ohio, 43214

Suspended

The Mark H Zangmeister Center

Columbus, Ohio, 43219

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

Miami Valley Hospital

Dayton, Ohio, 45409

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Michael S. Guy · Principal Investigator

Miami Valley Hospital North

Dayton, Ohio, 45415

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Michael S. Guy · Principal Investigator

Atrium Medical Center-Middletown Regional Hospital

Franklin, Ohio, 45005-1066

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Michael S. Guy · Principal Investigator

Miami Valley Cancer Care and Infusion

Greenville, Ohio, 45331

Recruiting
Site Public Contact · Contact
937-569-7515
Michael S. Guy · Principal Investigator

Mount Carmel Grove City Hospital

Grove City, Ohio, 43123

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

Fairfield Medical Center

Lancaster, Ohio, 43130

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

Saint Rita's Medical Center

Lima, Ohio, 45801

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

Marietta Memorial Hospital

Marietta, Ohio, 45750

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

Memorial Hospital

Marysville, Ohio, 43040

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

UH Seidman Cancer Center at Lake Health Mentor Campus

Mentor, Ohio, 44060

Recruiting
Site Public Contact · Contact
800-641-2422CTUReferral@UHhospitals.org
Amy Armstrong · Principal Investigator

Knox Community Hospital

Mount Vernon, Ohio, 43050

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

Licking Memorial Hospital

Newark, Ohio, 43055

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

University Hospitals Parma Medical Center

Parma, Ohio, 44129

Recruiting
Site Public Contact · Contact
800-641-2422CTUReferral@UHhospitals.org
Amy Armstrong · Principal Investigator

Mercy Health - Perrysburg Hospital

Perrysburg, Ohio, 43551

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

Southern Ohio Medical Center

Portsmouth, Ohio, 45662

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

Springfield Regional Cancer Center

Springfield, Ohio, 45504

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

Springfield Regional Medical Center

Springfield, Ohio, 45504

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

ProMedica Flower Hospital

Sylvania, Ohio, 43560

Recruiting
Site Public Contact · Contact
419-824-1842PCIOncResearch@promedica.org
Kathleen G. Essel · Principal Investigator

Mercy Health - Saint Vincent Hospital

Toledo, Ohio, 43608

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

Mercy Health - Saint Anne Hospital

Toledo, Ohio, 43623

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

Upper Valley Medical Center

Troy, Ohio, 45373

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Michael S. Guy · Principal Investigator

Saint Ann's Hospital

Westerville, Ohio, 43081

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

UH Seidman Cancer Center at Saint John Medical Center

Westlake, Ohio, 44145

Recruiting
Site Public Contact · Contact
800-641-2422CTUReferral@UHhospitals.org
Amy Armstrong · Principal Investigator

Genesis Healthcare System Cancer Care Center

Zanesville, Ohio, 43701

Recruiting
Site Public Contact · Contact
614-488-2745Jeffh@columbusccop.org
Aruna C. Gowda · Principal Investigator

University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104

Recruiting
Site Public Contact · Contact
405-271-8777ou-clinical-trials@ouhsc.edu
Lauren E. Dockery · Principal Investigator

Mercy Hospital Oklahoma City

Oklahoma City, Oklahoma, 73120

Recruiting
Site Public Contact · Contact
405-752-3402
Jay W. Carlson · Principal Investigator

Oklahoma Cancer Specialists and Research Institute-Tulsa

Tulsa, Oklahoma, 74146

Recruiting
Site Public Contact · Contact
918-505-3200
Katherine M. Moxley · Principal Investigator

Providence Cancer Institute Clackamas Clinic

Clackamas, Oregon, 97015

Suspended

Providence Newberg Medical Center

Newberg, Oregon, 97132

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Dan S. Zuckerman · Principal Investigator

Saint Alphonsus Cancer Care Center-Ontario

Ontario, Oregon, 97914

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
J. R. Liu · Principal Investigator

Legacy Good Samaritan Hospital and Medical Center

Portland, Oregon, 97210

Active Not Recruiting

Providence Portland Medical Center

Portland, Oregon, 97213

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Dan S. Zuckerman · Principal Investigator

Providence Saint Vincent Medical Center

Portland, Oregon, 97225

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Dan S. Zuckerman · Principal Investigator

Oregon Health and Science University

Portland, Oregon, 97239

Recruiting
Site Public Contact · Contact
503-494-1080trials@ohsu.edu
Jessica Jou · Principal Investigator

Legacy Meridian Park Hospital

Tualatin, Oregon, 97062

Active Not Recruiting

Lehigh Valley Hospital-Cedar Crest

Allentown, Pennsylvania, 18103

Recruiting
Site Public Contact · Contact
610-402-9543Morgan_M.Horton@lvhn.org
J. R. Liu · Principal Investigator

Saint Luke's Cancer Center - Allentown

Allentown, Pennsylvania, 18104

Recruiting
Site Public Contact · Contact
610-776-4714
Nicholas P. Taylor · Principal Investigator

Saint Luke's University Hospital-Bethlehem Campus

Bethlehem, Pennsylvania, 18015

Recruiting
Site Public Contact · Contact
484-503-4151
Nicholas P. Taylor · Principal Investigator

Lehigh Valley Hospital - Muhlenberg

Bethlehem, Pennsylvania, 18017

Recruiting
Site Public Contact · Contact
610-402-9543Morgan_M.Horton@lvhn.org
J. R. Liu · Principal Investigator

Bryn Mawr Hospital

Bryn Mawr, Pennsylvania, 19010

Recruiting
Site Public Contact · Contact
484-476-2649turzoe@mlhs.org
Deric C. Savior · Principal Investigator

Pocono Medical Center

East Stroudsburg, Pennsylvania, 18301

Recruiting
Site Public Contact · Contact
610-402-9543Morgan_M.Horton@lvhn.org
J. R. Liu · Principal Investigator

Saint Luke's Hospital-Anderson Campus

Easton, Pennsylvania, 18045

Recruiting
Site Public Contact · Contact
412-339-5294Roster@nrgoncology.org
Nicholas P. Taylor · Principal Investigator

Saint Vincent Hospital

Erie, Pennsylvania, 16544

Active Not Recruiting

Lehigh Valley Hospital-Hazleton

Hazleton, Pennsylvania, 18201

Recruiting
Site Public Contact · Contact
610-402-9543Morgan_M.Horton@lvhn.org
J. R. Liu · Principal Investigator

Jefferson Hospital

Jefferson Hills, Pennsylvania, 15025

Active Not Recruiting

Riddle Memorial Hospital

Media, Pennsylvania, 19063

Recruiting
Site Public Contact · Contact
484-476-2649turzoe@mlhs.org
Deric C. Savior · Principal Investigator

Forbes Hospital

Monroeville, Pennsylvania, 15146

Active Not Recruiting

Paoli Memorial Hospital

Paoli, Pennsylvania, 19301

Recruiting
Site Public Contact · Contact
484-476-2649turzoe@mlhs.org
Deric C. Savior · Principal Investigator

Pennsylvania Hospital

Philadelphia, Pennsylvania, 19107

Recruiting
Site Public Contact · Contact
215-349-8245PMCancerResearch@pennmedicine.upenn.edu
Patricia A. Locantore-Ford · Principal Investigator

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107

Recruiting
Site Public Contact · Contact
215-600-9151ONCTrialNow@jefferson.edu
Mitchell I. Edelson · Principal Investigator

Fox Chase Cancer Center

Philadelphia, Pennsylvania, 19111

Recruiting
Site Public Contact · Contact
215-728-4790
Angela Jain · Principal Investigator

West Penn Hospital

Pittsburgh, Pennsylvania, 15224

Active Not Recruiting

Saint Luke's Hospital - Upper Bucks Campus

Quakertown, Pennsylvania, 18951

Recruiting
Site Public Contact · Contact
610-776-4714
Nicholas P. Taylor · Principal Investigator

Chester County Hospital

West Chester, Pennsylvania, 19380

Recruiting
Site Public Contact · Contact
215-349-8245PMCancerResearch@pennmedicine.upenn.edu
Patricia A. Locantore-Ford · Principal Investigator

Wexford Health and Wellness Pavilion

Wexford, Pennsylvania, 15090

Active Not Recruiting

Asplundh Cancer Pavilion

Willow Grove, Pennsylvania, 19090

Recruiting
Site Public Contact · Contact
215-600-9151ONCTrialNow@jefferson.edu
Mitchell I. Edelson · Principal Investigator

Lankenau Medical Center

Wynnewood, Pennsylvania, 19096

Recruiting
Site Public Contact · Contact
484-476-2649turzoe@mlhs.org
Deric C. Savior · Principal Investigator

Women and Infants Hospital

Providence, Rhode Island, 02905

Recruiting
Site Public Contact · Contact
401-274-1122
Cara A. Mathews · Principal Investigator

Smilow Cancer Hospital Care Center - Westerly

Westerly, Rhode Island, 02891

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Alessandro D. Santin · Principal Investigator

Saint Joseph's/Candler - Bluffton Campus

Bluffton, South Carolina, 29910

Recruiting
Site Public Contact · Contact
912-819-5704underberga@sjchs.org
Sarah E. Gill · Principal Investigator

Medical University of South Carolina

Charleston, South Carolina, 29425

Recruiting
Site Public Contact · Contact
843-792-9321hcc-clinical-trials@musc.edu
Brian Orr · Principal Investigator

Avera Cancer Institute-Aberdeen

Aberdeen, South Dakota, 57401

Recruiting
Site Public Contact · Contact
605-622-8700oncregulatory@avera.org
David C. Starks · Principal Investigator

Rapid City Regional Hospital

Rapid City, South Dakota, 57701

Active Not Recruiting

Sanford Cancer Center Oncology Clinic

Sioux Falls, South Dakota, 57104

Recruiting
Site Public Contact · Contact
605-312-3320OncologyClinicTrialsSF@sanfordhealth.org
Maria C. Bell · Principal Investigator

Avera Cancer Institute

Sioux Falls, South Dakota, 57105

Recruiting
Site Public Contact · Contact
605-322-3095OncRegulatory@avera.org
David C. Starks · Principal Investigator

Sanford USD Medical Center - Sioux Falls

Sioux Falls, South Dakota, 57117-5134

Recruiting
Site Public Contact · Contact
605-312-3320OncologyClinicalTrialsSF@SanfordHealth.org
Maria C. Bell · Principal Investigator

The West Clinic - Wolf River

Germantown, Tennessee, 38138

Active Not Recruiting

Dell Seton Medical Center at The University of Texas

Austin, Texas, 78701

Recruiting
Site Public Contact · Contact
512-324-7991
Marian Y. Williams-Brown · Principal Investigator

University of Texas at Austin

Austin, Texas, 78712

Recruiting
Site Public Contact · Contact
512-232-1543irb@austin.utexas.edu
Marian Y. Williams-Brown · Principal Investigator

Parkland Memorial Hospital

Dallas, Texas, 75235

Recruiting
Site Public Contact · Contact
214-590-5582canceranswerline@UTSouthwestern.edu
Jayanthi S. Lea · Principal Investigator

UT Southwestern/Simmons Cancer Center-Dallas

Dallas, Texas, 75390

Recruiting
Site Public Contact · Contact
214-648-7097canceranswerline@UTSouthwestern.edu
Jayanthi S. Lea · Principal Investigator

Tarrant County Hospital District/JPS Health Network

Fort Worth, Texas, 76104

Recruiting
Site Public Contact · Contact
817-702-5913macosta02@jpshealth.org
Gennady Miroshnichenko · Principal Investigator

UT Southwestern/Simmons Cancer Center-Fort Worth

Fort Worth, Texas, 76104

Recruiting
Site Public Contact · Contact
214-648-7097canceranswerline@UTSouthwestern.edu
Jayanthi S. Lea · Principal Investigator

Houston Methodist Hospital

Houston, Texas, 77030

Recruiting
Site Public Contact · Contact
713-790-2700
Aparna A. Kamat · Principal Investigator

Memorial Hermann Texas Medical Center

Houston, Texas, 77030

Recruiting
Site Public Contact · Contact
713-792-3245
Joseph A. Lucci · Principal Investigator

Methodist Willowbrook Hospital

Houston, Texas, 77070

Recruiting
Site Public Contact · Contact
412-339-5294Roster@nrgoncology.org
Aparna A. Kamat · Principal Investigator

Houston Methodist West Hospital

Houston, Texas, 77094

Recruiting
Site Public Contact · Contact
832-522-2873
Aparna A. Kamat · Principal Investigator

Houston Methodist Saint John Hospital

Nassau Bay, Texas, 77058

Recruiting
Site Public Contact · Contact
412-339-5294Roster@nrgoncology.org
Aparna A. Kamat · Principal Investigator

UT Southwestern Clinical Center at Richardson/Plano

Richardson, Texas, 75080

Recruiting
Site Public Contact · Contact
972-669-7044Suzanne.cole@utsouthwestern.edu
Jayanthi S. Lea · Principal Investigator

Houston Methodist Sugar Land Hospital

Sugar Land, Texas, 77479

Recruiting
Site Public Contact · Contact
281-242-2873
Aparna A. Kamat · Principal Investigator

Houston Methodist The Woodlands Hospital

The Woodlands, Texas, 77385

Recruiting
Site Public Contact · Contact
713-790-2700hmthewoodlands@houstonmethodist.org
Aparna A. Kamat · Principal Investigator

Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112

Recruiting
Site Public Contact · Contact
888-424-2100cancerinfo@hci.utah.edu
Kristen Kelley · Principal Investigator

South Jordan Health Center

South Jordan, Utah, 84009

Recruiting
Site Public Contact · Contact
888-424-2100cancerinfo@hci.utah.edu
Kristen Kelley · Principal Investigator

University of Virginia Cancer Center

Charlottesville, Virginia, 22908

Recruiting
Site Public Contact · Contact
434-243-6303uvacancertrials@hscmail.mcc.virginia.edu
Kari L. Ring · Principal Investigator

Henrico Doctor's Hospital

Richmond, Virginia, 23229

Recruiting
Site Public Contact · Contact
804-591-4152
Andrew S. Kennedy · Principal Investigator

VCU Massey Cancer Center at Stony Point

Richmond, Virginia, 23235

Recruiting
Site Public Contact · Contact
ctoclinops@vcu.edu
Chelsea Salyer · Principal Investigator

VCU Massey Comprehensive Cancer Center

Richmond, Virginia, 23298

Recruiting
Site Public Contact · Contact
804-628-6430CTOclinops@vcu.edu
Chelsea Salyer · Principal Investigator

Carilion Roanoke Memorial Hospital

Roanoke, Virginia, 24033

Recruiting
Site Public Contact · Contact
540-985-8510
Chelsea Salyer · Principal Investigator

Swedish Cancer Institute-Edmonds

Edmonds, Washington, 98026

Recruiting
Site Public Contact · Contact
206-215-2343PCRC-NCORP@Swedish.org
Dan S. Zuckerman · Principal Investigator

Swedish Medical Center-First Hill

Seattle, Washington, 98122

Recruiting
Site Public Contact · Contact
206-215-2343PCRC-NCORP@Swedish.org
Dan S. Zuckerman · Principal Investigator

Legacy Salmon Creek Hospital

Vancouver, Washington, 98686

Active Not Recruiting

West Virginia University Charleston Division

Charleston, West Virginia, 25304

Recruiting
Site Public Contact · Contact
304-388-9944
Stephen H. Bush · Principal Investigator

West Virginia University Healthcare

Morgantown, West Virginia, 26506

Recruiting
Site Public Contact · Contact
304-293-7374cancertrialsinfo@hsc.wvu.edu
Krista S. Pfaendler · Principal Investigator

Marshfield Medical Center-EC Cancer Center

Eau Claire, Wisconsin, 54701

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

Saint Vincent Hospital Cancer Center Green Bay

Green Bay, Wisconsin, 54301

Recruiting
Site Public Contact · Contact
920-433-8889WI_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Saint Vincent Hospital Cancer Center at Saint Mary's

Green Bay, Wisconsin, 54303

Recruiting
Site Public Contact · Contact
920-433-8889wi_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Gundersen Lutheran Medical Center

La Crosse, Wisconsin, 54601

Recruiting
Site Public Contact · Contact
608-775-2385cancerctr@gundersenhealth.org
Kurt Oettel · Principal Investigator

University of Wisconsin Carbone Cancer Center - Eastpark Medical Center

Madison, Wisconsin, 53718

Recruiting
Site Public Contact · Contact
800-622-8922clinicaltrials@cancer.wisc.edu
Ellen M. Hartenbach · Principal Investigator

University of Wisconsin Carbone Cancer Center - University Hospital

Madison, Wisconsin, 53792

Recruiting
Site Public Contact · Contact
800-622-8922clinicaltrials@cancer.wisc.edu
Ellen M. Hartenbach · Principal Investigator

Marshfield Medical Center-Marshfield

Marshfield, Wisconsin, 54449

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

Medical College of Wisconsin

Milwaukee, Wisconsin, 53226

Recruiting
Site Public Contact · Contact
414-805-3666
William H. Bradley · Principal Investigator

Marshfield Medical Center - Minocqua

Minocqua, Wisconsin, 54548

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

ProHealth D N Greenwald Center

Mukwonago, Wisconsin, 53149

Recruiting
Site Public Contact · Contact
research.institute@phci.org
Timothy R. Wassenaar · Principal Investigator

Cancer Center of Western Wisconsin

New Richmond, Wisconsin, 54017

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
Jessica A. Thomes Pepin · Principal Investigator

ProHealth Oconomowoc Memorial Hospital

Oconomowoc, Wisconsin, 53066

Recruiting
Site Public Contact · Contact
262-928-7878
Timothy R. Wassenaar · Principal Investigator

Saint Vincent Hospital Cancer Center at Oconto Falls

Oconto Falls, Wisconsin, 54154

Recruiting
Site Public Contact · Contact
920-433-8889WI_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Marshfield Medical Center-Rice Lake

Rice Lake, Wisconsin, 54868

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

Saint Vincent Hospital Cancer Center at Sheboygan

Sheboygan, Wisconsin, 53081

Recruiting
Site Public Contact · Contact
920-433-8889wi_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Sheboygan Physicians Group

Sheboygan, Wisconsin, 53081

Recruiting
Site Public Contact · Contact
920-433-8889wi_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Marshfield Medical Center-River Region at Stevens Point

Stevens Point, Wisconsin, 54482

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

Saint Vincent Hospital Cancer Center at Sturgeon Bay

Sturgeon Bay, Wisconsin, 54235-1495

Recruiting
Site Public Contact · Contact
920-433-8889wi_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

UW Cancer Center at ProHealth Care

Waukesha, Wisconsin, 53188

Recruiting
Site Public Contact · Contact
262-928-5539Chanda.miller@phci.org
Timothy R. Wassenaar · Principal Investigator

Marshfield Medical Center - Weston

Weston, Wisconsin, 54476

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

References

  • Secord AA, Powell MA, McAlpine J. Molecular Characterization and Clinical Implications of Endometrial Cancer. Obstet Gynecol. 2025 Nov 1;146(5):660-671. doi: 10.1097/AOG.0000000000006080. Epub 2025 Sep 18.(PubMed)