Aromatherapy Inhaler Use for Hematopoietic Stem Cell Transplant Patient Distress
Summary
This randomized controlled trial will evaluate the feasibility and acceptability of an inhaled aromatherapy stick for patients during the acute inpatient phase after hematopoietic cell transplantation (HCT) . The study will also explore whether aromatherapy use is associated with short-term changes in patient-reported cancer-related distress and coping self-efficacy.
Detailed description
Patients undergoing hematopoietic cell transplantation (HCT) commonly experience high levels of distress and other symptoms during the acute inpatient period. Inhaled aromatherapy is a low-burden, patient-directed supportive care strategy that may be feasible to deliver during hospitalization. This randomized, parallel-group study will evaluate the feasibility and acceptability of an aromatherapy inhaler ("aromatherapy stick") during the early post-transplant inpatient period and will explore short-term changes in patient-reported outcomes.
Arms & interventions
- OtherAromatherapy Stick
Participants receive aromatherapy inhaler education and an aromatherapy stick for self-administered inhalation during the early post-transplant inpatient period. Aromatherapy use occurs on the assigned Inhaler Use Day (targeted for Transplant Day +1, +2, or +3) and is documented using an inhaler use log. Total exposure is limited to a maximum of 2 hours.
- OtherStandard of Care
Participants receive standard inpatient supportive care during the acute post-HCT period. No aromatherapy inhaler is provided.
Outcome measures
Primary
Change in cancer distress (NCCN Distress Thermometer)
Change in NCCN Distress Thermometer score (0-10 visual analog scale). Calculated as follow-up score minus baseline score.
Time frame: Baseline: SOC/Inhaler Use Day (Transplant Day +1, +2, or +3); Follow-up: Study Completion Day (Transplant Day +2, +3, or +4)
Secondary
Change in cancer coping self-efficacy (Cancer Behavior Inventory-Brief Form, modified)
Time frame: Baseline: SOC/Inhaler Use Day (Transplant Day +1, +2, or +3); Follow-up: Study Completion Day (Transplant Day +2, +3, or +4)
Aromatherapy Inhaler Use Log (Inhaler Use Log)
Time frame: 1 day (Inhaler Use Day)
Aromatherapy experience (Final Evaluation of Aromatherapy)
Time frame: Study Completion Day (Transplant Day +4, +5, or +6)
Eligibility criteria
Study locations (1)
Stanford University
Stanford, California, 94305