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Highlighting Patients At Risk for Sensory Screening (HPARSS) to Enhance Sensory Deficit Screening in Childhood Cancer Survivors

NCT ID: NCT05582551Sponsor: Washington University School of MedicineLast updated: 2026-06-15

Summary

The overall goal of this study is to attempt to overcome the organizational barriers that impede prompt screening for at-risk sensory deficits in childhood cancer survivors (CCS). Using a cross sectional design study, collaborators in the Informatics Research branch of the Institute of Informatics at the Washington University School of Medicine will identify CCS at risk for sensory deficits based upon their therapy exposure to generate the highlighting patients at risk for sensory screening (HPARSS) document. The investigators will utilize the HPARSS that will link therapy related risks for sensory deficits to specific screening procedures prompting the primary oncology provider to implement screening, diagnostic testing, and therapy.

Arms & interventions

  • OtherHighlighting Patients at Risk for Sensory Screening (HPARSS)

    Collaborators in the Informatics Research branch of the Institute of Informatics at the Washington University School of Medicine will identify CCS at risk for sensory deficits based upon their therapy exposure to generate the HPARSS document.

Outcome measures

Primary

  • Percentage of patients with at risk for sensory deficits identified by HPARSS

    Time frame: Through completion of enrollment for all patients (estimated to be 9 months)

  • Percentage of at risk patients who fail the assigned screening test

    Time frame: Through completion of enrollment for all patients (estimated to be 9 months)

  • Percentage of patients in need of referral for screen test results who participate in formal diagnostic testing and/or treatment

    Time frame: Through 1 year after the completion of screening test for all participants (estimated to be 1 year and 9 months)

Secondary

  • Number and types of barriers to participation in formal diagnostic testing and therapy in CCS failing to engage in sensory screening

    Time frame: At approximately 2 months following the patient's screening

  • Number and types of facilitators to participation in formal diagnostic testing and therapy in CCS failing to engage in sensory screening

    Time frame: At approximately 2 months following the patient's screening

  • Acceptability of HPARSS as measured by the Acceptability of Intervention Measure (AIM)

    Time frame: To be completed at the time of enrollment completion (approximately 9 months)

  • Feasibility of intervention as measured by Feasibility of Intervention Measure (FIM)

    Time frame: To be completed at the time of enrollment completion (approximately 9 months)

Eligibility criteria

Sex: AllAge: 7 Years to 17 YearsHealthy volunteers: No
Inclusion Criteria: * Patients with a diagnosis of pediatric cancer (diagnosis at \<18 years of age) * Treatment including chemotherapy and/or radiation therapy * Completion of all cancer therapy for at least 6 months and less than 2 years * Followed in the Division of Pediatric Hematology/Oncology Program at the Washington University School of Medicine * Current age between 7 and 17 years of age (age where all of the screening tests are both valid and have been successfully performed by our group) * English speaking Exclusion Criteria: * Undergoing active cancer treatment * Patient under the care of the Late Effects Program at St. Louis Children's Hospital * Received previous diagnostic testing or rehabilitative therapy for a secondary deficit eligible for screening. * Parents and/or patient illiteracy * No contact with treatment team in the past two years * In foster care or without a legal guardian

Study locations (1)

St. Louis Children's Hospital - Washington University School of Medicine

St Louis, Missouri, 63110

Recruiting
Robert J Hayashi, M.D. · Contact
Robert J Hayashi, M.D. · Principal Investigator
Ashley Housten, OTD, MSCI · Sub Investigator
Thomas Kannampallil, Ph.D. · Sub Investigator
Patrick Lyons, M.D., MSc · Sub Investigator
Susan Hayashi, MA · Sub Investigator
Belinda Sinks, AUD · Sub Investigator
Anna Perlmutter, OTR/L · Sub Investigator
Feng Gao, M.D., Ph.D., MPH, MS · Sub Investigator