Back to clinical trials
RecruitingObservational
Multi-Cancer Early Detection (MCED) of Firefighters
NCT ID: NCT05780957Sponsor: Vincere Cancer CenterLast updated: 2025-11-05
Summary
This study is an an observational prospective cohort research study to explore the performance of new blood and urine tests for the early detection of cancer among firefighters.
Arms & interventions
- OtherMCED
multi-cancer early detection (MCED) test
Outcome measures
Primary
Sensitivity, specificity, positive and negative predictive performance values (PPV and NPV) to detect cancer using Elypta's MCED test, as measured in plasma, in urine, and in plasma and urine combined
Time frame: Up to 7 years
Sensitivity, specificity, positive and negative predictive performance values to detect cancer using Proteotype's MCED test, as measured in plasma.
Time frame: Up to 2030
Eligibility criteria
Sex: AllAge: 18 Years and olderHealthy volunteers: Yes
Inclusion Criteria:
* 18 years of age or older
* Currently employed as a firefighter, full-time or part-time
* Taking part in Vincere's First Responder Cancer Screening Program
* Able to donate blood and urine sample
* Able to provide informed consent to participate in the study
Exclusion Criteria:
* Deemed medically unfit for sample donation
* Personal history of cancer in the last 5 years (with the exception of non-melanoma skin cancer)
Study locations (1)
Vincere Cancer Center
Scottsdale, Arizona, 85260
Vershalee Shukla, MD · Principal Investigator