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RecruitingObservational

Health Opportunities and Promoters of Equitable Screening for Lung Cancer (HOPES for Lung Cancer)

NCT ID: NCT05784922Sponsor: Massachusetts General HospitalLast updated: 2025-10-14

Summary

The goal of this clinical trial is to promote lung cancer screening (LCS) uptake among Hispanic current and former smokers. The main questions it aims to answer are: * What barriers do current and former Hispanic smokers face in the identification and documentation of their smoking status? * How can digital delivery of an educational video promote LCS uptake among current and former Hispanic smokers? Participants will receive an educational video about lung cancer screening and complete brief, self-reported surveys afterwards.

Detailed description

Lung cancer remains the leading cause of cancer-specific mortality in the US, and Hispanics experience worse lung cancer outcomes and die at higher rates due to advanced stage at presentation. Lung cancer screening (LCS) can save many lives through early lung cancer detection among Hispanic current and former smokers. Still, without increasing efforts to improve smoking status disclosure and documentation and tailored interventions to promote LCS uptake among Hispanic current and former smokers, this underserved population will continue to demonstrate disparities in lung cancer survival. Based on prior research experience, Dr. Flores has adapted the NIMHD research framework by incorporating elements from Ford's evidence-based theoretical model to guide the following proposed study aims: 1\) To elucidate barriers and facilitators to consistent identification and documentation of smoking status to promote LCS uptake among Hispanic current and former smokers; 2) To assess feasibility, acceptability, and reach of the digital delivery of an educational video to promote LCS uptake among Hispanic current and former smokers; 3) To explore the effect of the digital delivery of the educational video to increase interest, intent, and scheduling of LCS uptake among Hispanic current and former smokers. Impact: The successful completion of this research will serve as a foundation for developing novel interventions to overcome disparities and advance equity in lung cancer outcomes among Hispanics and other vulnerable populations.

Arms & interventions

  • OtherEducational Lung Cancer Screening (LCS) Video

    An educational video on lung cancer screening tailored to Hispanic current and former smokers.

Outcome measures

Primary

  • Participant outreach (contact) of digital link

    Reach is defined as \>20% of enrolled participants interacting with the digital delivery of the LCS educational video (i.e., partial or complete review of the LCS educational video).

    Time frame: Year 3

Secondary

  • Participant interaction with digital link

    Time frame: Year 3

  • Participant attention of LCS video

    Time frame: Year 3

  • Survey completion

    Time frame: Year 4

Eligibility criteria

Sex: AllAge: 50 Years to 80 YearsHealthy volunteers: No
Inclusion Criteria: * Must be 50-80 years old * Are a current or former smoker (quit within 15 years, or a cumulative smoking status of \> 20 pack-years) * Not currently enrolled in Lung Cancer Screening * Must speak English or Spanish Exclusion Criteria: * Has a clinical cognitive inability to provide informed consent for participation in the study or complete a brief survey * Currently diagnosed with lung cancer * Currently enrolled in lung cancer screening * Have participated in the focus groups discussions from Aim 1

Study locations (1)

Massachusetts General Hospital

Boston, Massachusetts, 02114

Recruiting
Elyse Park, PhD · Contact
Efren Flores, MD · Principal Investigator

References

  • Narayan AK, Chowdhry DN, Fintelmann FJ, Little BP, Shepard JO, Flores EJ. Racial and Ethnic Disparities in Lung Cancer Screening Eligibility. Radiology. 2021 Dec;301(3):712-720. doi: 10.1148/radiol.2021204691. Epub 2021 Sep 21.(PubMed)
  • Percac-Lima S, Ashburner JM, Atlas SJ, Rigotti NA, Flores EJ, Kuchukhidze S, Park ER. Barriers to and Interest in Lung Cancer Screening Among Latino and Non-Latino Current and Former Smokers. J Immigr Minor Health. 2019 Dec;21(6):1313-1324. doi: 10.1007/s10903-019-00860-2.(PubMed)
  • Wang GX, Neil JM, Fintelmann FJ, Little BP, Narayan AK, Flores EJ. Guideline-Discordant Lung Cancer Screening: Emerging Demand and Provided Indications. J Am Coll Radiol. 2021 Mar;18(3 Pt A):395-405. doi: 10.1016/j.jacr.2020.08.005. Epub 2020 Sep 6.(PubMed)
  • Flores EJ, Park ER, Irwin KE. Improving Lung Cancer Screening Access for Individuals With Serious Mental Illness. J Am Coll Radiol. 2019 Apr;16(4 Pt B):596-600. doi: 10.1016/j.jacr.2018.12.045.(PubMed)
  • Irwin KE, Steffens EB, Yoon Y, Flores EJ, Knight HP, Pirl WF, Freudenreich O, Henderson DC, Park ER. Lung Cancer Screening Eligibility, Risk Perceptions, and Clinician Delivery of Tobacco Cessation Among Patients With Schizophrenia. Psychiatr Serv. 2019 Oct 1;70(10):927-934. doi: 10.1176/appi.ps.201900044. Epub 2019 Jul 30.(PubMed)
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