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RecruitingInterventionalPhase 2

S2210 A Phase II Study of Neoadjuvant Carboplatin for Localized, High Risk Prostate Cancer With Germline BRCA1/2 Mutations

NCT ID: NCT05806515Sponsor: SWOG Cancer Research NetworkLast updated: 2026-01-29

Summary

This phase II trial tests how well carboplatin before surgery works in treating patients with high-risk prostate cancer and an inherited BRCA1 or BRCA2 gene mutation. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping, or slowing the growth of tumor cells. Giving carboplatin before surgery may shrink tumors in patients with high-risk prostate cancer with BRCA1 and BRCA2 gene mutations.

Detailed description

PRIMARY OBJECTIVE: I. To evaluate the pathologic complete response rate at prostatectomy in patients with localized high-risk prostate cancer with germline BRCA2 or BRCA1 mutations who are treated with neoadjuvant carboplatin by central review of source documents. SECONDARY OBJECTIVES: I. To evaluate prostate specific antigen (PSA) progression-free survival post-prostatectomy over the duration of follow-up and specifically, at the 3-year landmark. II. To evaluate metastases free survival and overall survival. III. To evaluate the frequency and severity of toxicities of neoadjuvant carboplatin followed by radical prostatectomy. BANKING OBJECTIVE: I. To bank specimens for future correlative studies. OUTLINE: Patients receive carboplatin intravenously (IV) on study. Patients then undergo surgery on study. Patients who experience PSA progression after surgery undergo computed tomography (CT) or magnetic resonance imaging (MRI) of the abdomen and pelvis, CT of the chest or chest X-ray, or prostate-specific membrane antigen (PSMA)-positron emission tomography (PET) throughout the trial. Patients also undergo collection of blood samples throughout the trial.

Arms & interventions

  • ProcedureBiospecimen Collection

    Undergo collection of blood samples

  • DrugCarboplatin

    Given IV

  • ProcedureChest Radiography

    Undergo chest X-ray

  • ProcedureComputed Tomography

    Undergo CT

  • ProcedureMagnetic Resonance Imaging

    Undergo MRI

  • ProcedurePSMA PET Scan

    Undergo PSMA PET

  • ProcedureSurgical Procedure

    Undergo surgery

Outcome measures

Primary

  • Pathologic complete response after neoadjuvant carboplatin

    A two-stage design will be used.

    Time frame: Up to 5 years

Eligibility criteria

Sex: MaleAge: 18 Years and olderHealthy volunteers: No
Inclusion Criteria: * Participant must have histologic diagnosis of prostate adenocarcinoma * Participant must have high or very high-risk disease defined by at least one of the following: * cT3a - cT4x * Grade group 4 or 5 (Gleason sum 8-10) * PSA \> 20 ng/mL prior to registration * Participant must have documented evidence of germline mutation (pathogenic/likely pathogenic variant) in BRCA2 or BRCA1 through testing in a Clinical Laboratory Improvement Act (CLIA)-certified lab * NOTE: Local lab report is sufficient for eligibility * Participant may have initiated gonadotrophin releasing hormone (gnRH) agonist, gnRH antagonist, oral anti-androgen (e.g. bicalutamide, nilutamide, flutamide), or other agent intended to treat prostate cancer prior to registration. The effectiveness of the current depot of such treatment must not extend beyond 1 month after study registration. Agents listed above cannot be started after participant registration * Participant must be \>= 18 years old * Participant must have Zubrod performance status of 0-2 * Participant must have a complete medical history and physical exam within 28 days prior to registration * Absolute neutrophil count \>= 1.5 x 10\^3/uL (within 28 days prior to registration) * Platelets \>= 100 x 10\^3/uL (within 28 days prior to registration) * Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =\< 3 x institutional upper limit of normal (ULN) (within 28 days prior to registration) * Participant must have a serum creatinine =\< the institutional upper limit of normal (IULN) OR measured OR calculated creatinine clearance \>= 50 mL/min using the following Cockcroft-Gault Formula. This specimen must have been drawn and processed within 28 days prior to registration * Participant must have adequate cardiac function. Participants with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, must have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification within 28 days prior to registration. To be eligible for this trial, participants must be class 2B or better * Participant with known human immunodeficiency virus (HIV)-infection must be receiving anti-retroviral therapy and have an undetectable viral load test within 6 months prior to registration * Participant with history of chronic hepatitis B virus (HBV) infection must have undetectable HBV viral load on suppressive therapy within in 28 days prior to registration * Participant with a history of hepatitis C virus (HCV) infection must have been treated and cured. For participants with HCV infection who are currently on treatment must have an undetectable HCV viral load within in 28 days prior to registration * Participants who are of reproductive potential must have agreed to use an effective contraceptive method with details provided as a part of the consent process. A person who has semen likely to contain sperm is considered to be of "reproductive potential." In addition to routine contraceptive methods, "effective contraception" also includes refraining from sexual activity that might result in pregnancy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) including vasectomy with testing showing no sperm in the semen * Prior to registration, participant must have had a urologic consult and be deemed a surgical candidate with known sites of disease deemed by the urologist to be potentially resectable * Participants must be offered the opportunity to participate in specimen banking. With participant consent, specimens must be collected and submitted via the Southwest Oncology Group (SWOG) Specimen Tracking System * NOTE: As a part of the OPEN registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system * Participants must be informed of the investigational nature of this study and must sign and give informed consent in accordance with institutional and federal guidelines * For participants with impaired decision-making capabilities, legally authorized representatives may sign and give informed consent on behalf of study participants in accordance with applicable federal, local, and Central Institutional Review Board (CIRB) regulations * As part of the registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system Exclusion Criteria: * Participant must not have evidence of distant metastatic disease by conventional imaging within 90 days prior to registration * NOTE: cN1 detected only by PSMA-PET is permitted if urologist deems sites of disease to be potentially completely resectable * Participant must not have received prior radiation therapy (RT) to the pelvic region * Participant must not have a prior or concurrent malignancy whose natural history or treatment (in the opinion of the treating physician) has the potential to interfere with the safety or efficacy assessment of protocol treatment

Study locations (133)

Anchorage Associates in Radiation Medicine

Anchorage, Alaska, 98508

Recruiting
Site Public Contact · Contact
907-212-6871AKPAMC.OncologyResearchSupport@providence.org
Charles W. Drescher · Principal Investigator

Anchorage Radiation Therapy Center

Anchorage, Alaska, 99504

Recruiting
Site Public Contact · Contact
907-212-6871AKPAMC.OncologyResearchSupport@providence.org
Charles W. Drescher · Principal Investigator

Alaska Breast Care and Surgery LLC

Anchorage, Alaska, 99508

Recruiting
Site Public Contact · Contact
907-212-6871AKPAMC.OncologyResearchSupport@providence.org
Charles W. Drescher · Principal Investigator

Alaska Oncology and Hematology LLC

Anchorage, Alaska, 99508

Recruiting
Site Public Contact · Contact
907-212-6871AKPAMC.OncologyResearchSupport@providence.org
Charles W. Drescher · Principal Investigator

Alaska Women's Cancer Care

Anchorage, Alaska, 99508

Recruiting
Site Public Contact · Contact
907-212-6871AKPAMC.OncologyResearchSupport@providence.org
Charles W. Drescher · Principal Investigator

Anchorage Oncology Centre

Anchorage, Alaska, 99508

Recruiting
Site Public Contact · Contact
907-212-6871AKPAMC.OncologyResearchSupport@providence.org
Charles W. Drescher · Principal Investigator

Katmai Oncology Group

Anchorage, Alaska, 99508

Recruiting
Site Public Contact · Contact
907-212-6871AKPAMC.OncologyResearchSupport@providence.org
Charles W. Drescher · Principal Investigator

Providence Alaska Medical Center

Anchorage, Alaska, 99508

Recruiting
Site Public Contact · Contact
907-212-6871AKPAMC.OncologyResearchSupport@providence.org
Charles W. Drescher · Principal Investigator

Cancer Center at Saint Joseph's

Phoenix, Arizona, 85004

Recruiting
Site Public Contact · Contact
602-406-0777Research-cancerinstitute@dignityhealth.org
Shahzad Siddique · Principal Investigator

Mission Hope Medical Oncology - Arroyo Grande

Arroyo Grande, California, 93420

Recruiting
Site Public Contact · Contact
805-219-4673ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Providence Saint Joseph Medical Center/Disney Family Cancer Center

Burbank, California, 91505

Recruiting
Site Public Contact · Contact
818-847-4793Najee.Boucher@providence.org
Charles W. Drescher · Principal Investigator

Mercy Cancer Center �� Carmichael

Carmichael, California, 95608

Recruiting
Site Public Contact · Contact
protocols@swog.org
Shahzad Siddique · Principal Investigator

Mercy San Juan Medical Center

Carmichael, California, 95608

Recruiting
Site Public Contact · Contact
916-556-3301OncologyResearch@DignityHealth.org
Shahzad Siddique · Principal Investigator

City of Hope Comprehensive Cancer Center

Duarte, California, 91010

Recruiting
Site Public Contact · Contact
800-826-4673becomingapatient@coh.org
Wesley Yip · Principal Investigator

Mercy Cancer Center - Elk Grove

Elk Grove, California, 95758

Recruiting
Site Public Contact · Contact
916-556-3301OncologyResearch@DignityHealth.org
Shahzad Siddique · Principal Investigator

City of Hope at Irvine Lennar

Irvine, California, 92618

Recruiting
Site Public Contact · Contact
877-467-3411
Wesley Yip · Principal Investigator

Providence Queen of The Valley

Napa, California, 94558

Recruiting
Site Public Contact · Contact
707-521-3830
Charles W. Drescher · Principal Investigator

Mercy Cancer Center - Rocklin

Rocklin, California, 95765

Recruiting
Site Public Contact · Contact
916-556-3301OncologyResearch@DignityHealth.org
Shahzad Siddique · Principal Investigator

Mercy Cancer Center - Sacramento

Sacramento, California, 95816

Recruiting
Site Public Contact · Contact
916-556-3301OncologyResearch@DignityHealth.org
Shahzad Siddique · Principal Investigator

Pacific Central Coast Health Center-San Luis Obispo

San Luis Obispo, California, 93401

Recruiting
Site Public Contact · Contact
805-219-4673ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Mission Hope Medical Oncology - Santa Maria

Santa Maria, California, 93444

Recruiting
Site Public Contact · Contact
805-219-4673ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Providence Medical Foundation - Santa Rosa

Santa Rosa, California, 95403

Recruiting
Site Public Contact · Contact
707-521-3830
Charles W. Drescher · Principal Investigator

Providence Santa Rosa Memorial Hospital

Santa Rosa, California, 95405

Recruiting
Site Public Contact · Contact
707-521-3830
Charles W. Drescher · Principal Investigator

Woodland Memorial Hospital

Woodland, California, 95695

Recruiting
Site Public Contact · Contact
916-556-3301OncologyResearch@DignityHealth.org
Shahzad Siddique · Principal Investigator

Penrose-Saint Francis Healthcare

Colorado Springs, Colorado, 80907

Recruiting
Site Public Contact · Contact
719-776-6550ResearchTracking@Centura.Org
Shahzad Siddique · Principal Investigator

Rocky Mountain Cancer Centers-Penrose

Colorado Springs, Colorado, 80907

Recruiting
Site Public Contact · Contact
719-776-6550ResearchTracking@Centura.Org
Shahzad Siddique · Principal Investigator

Saint Francis Cancer Center

Colorado Springs, Colorado, 80923

Recruiting
Site Public Contact · Contact
719-776-6550ResearchTracking@Centura.Org
Shahzad Siddique · Principal Investigator

Porter Adventist Hospital

Denver, Colorado, 80210

Recruiting
Site Public Contact · Contact
719-776-6550ResearchTracking@Centura.Org
Shahzad Siddique · Principal Investigator

Mercy Medical Center

Durango, Colorado, 81301

Recruiting
Site Public Contact · Contact
719-776-6550ResearchTracking@Centura.Org
Shahzad Siddique · Principal Investigator

Southwest Oncology PC

Durango, Colorado, 81301

Recruiting
Site Public Contact · Contact
719-776-6550ResearchTracking@Centura.Org
Shahzad Siddique · Principal Investigator

Saint Anthony Hospital

Lakewood, Colorado, 80228

Recruiting
Site Public Contact · Contact
719-776-6550ResearchTracking@Centura.Org
Shahzad Siddique · Principal Investigator

Littleton Adventist Hospital

Littleton, Colorado, 80122

Recruiting
Site Public Contact · Contact
719-776-6550ResearchTracking@Centura.Org
Shahzad Siddique · Principal Investigator

Longmont United Hospital

Longmont, Colorado, 80501

Recruiting
Site Public Contact · Contact
719-776-6550ResearchTracking@Centura.Org
Shahzad Siddique · Principal Investigator

Parker Adventist Hospital

Parker, Colorado, 80138

Recruiting
Site Public Contact · Contact
719-776-6550ResearchTracking@Centura.Org
Shahzad Siddique · Principal Investigator

Saint Mary Corwin Medical Center

Pueblo, Colorado, 81004

Recruiting
Site Public Contact · Contact
719-776-6550ResearchTracking@Centura.Org
Shahzad Siddique · Principal Investigator

Smilow Cancer Hospital-Derby Care Center

Derby, Connecticut, 06418

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Joseph W. Kim · Principal Investigator

Smilow Cancer Hospital Care Center-Fairfield

Fairfield, Connecticut, 06824

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Joseph W. Kim · Principal Investigator

Smilow Cancer Hospital Care Center at Glastonbury

Glastonbury, Connecticut, 06033

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Joseph W. Kim · Principal Investigator

Smilow Cancer Hospital Care Center at Greenwich

Greenwich, Connecticut, 06830

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Joseph W. Kim · Principal Investigator

Smilow Cancer Hospital Care Center - Guilford

Guilford, Connecticut, 06437

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Joseph W. Kim · Principal Investigator

Smilow Cancer Hospital Care Center at Saint Francis

Hartford, Connecticut, 06105

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Joseph W. Kim · Principal Investigator

Smilow Cancer Center/Yale-New Haven Hospital

New Haven, Connecticut, 06510

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Joseph W. Kim · Principal Investigator

Yale University

New Haven, Connecticut, 06520

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Joseph W. Kim · Principal Investigator

Yale-New Haven Hospital North Haven Medical Center

North Haven, Connecticut, 06473

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Joseph W. Kim · Principal Investigator

Smilow Cancer Hospital Care Center at Long Ridge

Stamford, Connecticut, 06902

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Joseph W. Kim · Principal Investigator

Smilow Cancer Hospital-Torrington Care Center

Torrington, Connecticut, 06790

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Joseph W. Kim · Principal Investigator

Smilow Cancer Hospital Care Center-Trumbull

Trumbull, Connecticut, 06611

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Joseph W. Kim · Principal Investigator

Smilow Cancer Hospital-Waterbury Care Center

Waterbury, Connecticut, 06708

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Joseph W. Kim · Principal Investigator

Smilow Cancer Hospital Care Center - Waterford

Waterford, Connecticut, 06385

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Joseph W. Kim · Principal Investigator

Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706

Recruiting
Site Public Contact · Contact
734-712-3671stephanie.couch@stjoeshealth.org
John M. Schallenkamp · Principal Investigator

Saint Luke's Cancer Institute - Boise

Boise, Idaho, 83712

Recruiting
Site Public Contact · Contact
208-381-2774eslinget@slhs.org
Charles W. Drescher · Principal Investigator

Saint Alphonsus Cancer Care Center-Caldwell

Caldwell, Idaho, 83605

Recruiting
Site Public Contact · Contact
734-712-3671stephanie.couch@stjoeshealth.org
John M. Schallenkamp · Principal Investigator

Kootenai Health - Coeur d'Alene

Coeur d'Alene, Idaho, 83814

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Walter Knox Memorial Hospital

Emmett, Idaho, 83617

Recruiting
Site Public Contact · Contact
734-712-3671stephanie.couch@stjoeshealth.org
John M. Schallenkamp · Principal Investigator

Saint Luke's Cancer Institute - Fruitland

Fruitland, Idaho, 83619

Recruiting
Site Public Contact · Contact
208-381-2774eslinget@slhs.org
Charles W. Drescher · Principal Investigator

Idaho Urologic Institute-Meridian

Meridian, Idaho, 83642

Recruiting
Site Public Contact · Contact
734-712-3671stephanie.couch@stjoeshealth.org
John M. Schallenkamp · Principal Investigator

Saint Luke's Cancer Institute - Meridian

Meridian, Idaho, 83642

Recruiting
Site Public Contact · Contact
208-381-2774eslinget@slhs.org
Charles W. Drescher · Principal Investigator

Saint Luke's Cancer Institute - Nampa

Nampa, Idaho, 83686

Recruiting
Site Public Contact · Contact
208-381-2774eslinget@slhs.org
Charles W. Drescher · Principal Investigator

Saint Alphonsus Cancer Care Center-Nampa

Nampa, Idaho, 83687

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Kootenai Clinic Cancer Services - Post Falls

Post Falls, Idaho, 83854

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Kootenai Cancer Clinic

Sandpoint, Idaho, 83864

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Saint Luke's Cancer Institute - Twin Falls

Twin Falls, Idaho, 83301

Recruiting
Site Public Contact · Contact
208-381-2774eslinget@slhs.org
Charles W. Drescher · Principal Investigator

NorthShore University HealthSystem-Evanston Hospital

Evanston, Illinois, 60201

Recruiting
Site Public Contact · Contact
847-570-2109
Nicklas R. Pfanzelter · Principal Investigator

NorthShore University HealthSystem-Glenbrook Hospital

Glenview, Illinois, 60026

Recruiting
Site Public Contact · Contact
847-570-2109
Nicklas R. Pfanzelter · Principal Investigator

NorthShore University HealthSystem-Highland Park Hospital

Highland Park, Illinois, 60035

Recruiting
Site Public Contact · Contact
847-570-2109
Nicklas R. Pfanzelter · Principal Investigator

North Shore Medical Center

Skokie, Illinois, 60076

Recruiting
Site Public Contact · Contact
888-823-5923ctsucontact@westat.com
Nicklas R. Pfanzelter · Principal Investigator

Alegent Health Mercy Hospital

Council Bluffs, Iowa, 51503

Recruiting
Site Public Contact · Contact
402-717-1510ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Flaget Memorial Hospital

Bardstown, Kentucky, 40004

Recruiting
Site Public Contact · Contact
859-629-7169ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Commonwealth Cancer Center-Corbin

Corbin, Kentucky, 40701

Recruiting
Site Public Contact · Contact
859-629-7169ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Saint Joseph Hospital

Lexington, Kentucky, 40504

Recruiting
Site Public Contact · Contact
protocols@swog.org
Shahzad Siddique · Principal Investigator

Saint Joseph Radiation Oncology Resource Center

Lexington, Kentucky, 40504

Recruiting
Site Public Contact · Contact
859-629-7169ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Saint Joseph Hospital East

Lexington, Kentucky, 40509

Recruiting
Site Public Contact · Contact
859-629-7169ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Saint Joseph London

London, Kentucky, 40741

Recruiting
Site Public Contact · Contact
859-629-7169ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Saint Joseph Mount Sterling

Mount Sterling, Kentucky, 40353

Recruiting
Site Public Contact · Contact
protocols@swog.org
Shahzad Siddique · Principal Investigator

LSU Healthcare Network / Metairie Multi-Specialty Clinic

Metairie, Louisiana, 70006

Recruiting
Site Public Contact · Contact
504-210-3539emede1@lsuhsc.edu
Scott E. Delacroix · Principal Investigator

Louisiana State University Health Science Center

New Orleans, Louisiana, 70112

Recruiting
Site Public Contact · Contact
504-210-3539emede1@lsuhsc.edu
Scott E. Delacroix · Principal Investigator

Community Hospital of Anaconda

Anaconda, Montana, 59711

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Billings Clinic Cancer Center

Billings, Montana, 59101

Recruiting
Site Public Contact · Contact
800-996-2663research@billingsclinic.org
John M. Schallenkamp · Principal Investigator

Bozeman Deaconess Hospital

Bozeman, Montana, 59715

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Benefis Healthcare- Sletten Cancer Institute

Great Falls, Montana, 59405

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Great Falls Clinic

Great Falls, Montana, 59405

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Kalispell Regional Medical Center

Kalispell, Montana, 59901

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Saint Patrick Hospital - Community Hospital

Missoula, Montana, 59802

Recruiting
Site Public Contact · Contact
406-327-3118amy.hanneman@providence.org
Charles W. Drescher · Principal Investigator

Community Medical Hospital

Missoula, Montana, 59804

Suspended

CHI Health Good Samaritan

Kearney, Nebraska, 68847

Recruiting
Site Public Contact · Contact
308-865-7963ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Saint Elizabeth Regional Medical Center

Lincoln, Nebraska, 68510

Recruiting
Site Public Contact · Contact
855-313-2409ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Alegent Health Immanuel Medical Center

Omaha, Nebraska, 68122

Recruiting
Site Public Contact · Contact
402-717-1510ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Alegent Health Bergan Mercy Medical Center

Omaha, Nebraska, 68124

Recruiting
Site Public Contact · Contact
402-717-1510ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Alegent Health Lakeside Hospital

Omaha, Nebraska, 68130

Recruiting
Site Public Contact · Contact
402-717-1510ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Creighton University Medical Center

Omaha, Nebraska, 68131

Recruiting
Site Public Contact · Contact
402-717-1510ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Midlands Community Hospital

Papillion, Nebraska, 68046

Recruiting
Site Public Contact · Contact
402-717-1510ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Garnet Health Medical Center

Middletown, New York, 10940

Recruiting
Site Public Contact · Contact
845-333-1133jgerlach@garnethealth.org
Jeffrey M. Stewart · Principal Investigator

Good Samaritan Hospital - Cincinnati

Cincinnati, Ohio, 45220

Recruiting
Site Public Contact · Contact
513-853-1300ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Bethesda North Hospital

Cincinnati, Ohio, 45242

Recruiting
Site Public Contact · Contact
513-853-1300ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

TriHealth Cancer Institute-Westside

Cincinnati, Ohio, 45247

Recruiting
Site Public Contact · Contact
513-853-1300ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

TriHealth Cancer Institute-Anderson

Cincinnati, Ohio, 45255

Recruiting
Site Public Contact · Contact
513-853-1300ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104

Recruiting
Site Public Contact · Contact
405-271-8777ou-clinical-trials@ouhsc.edu
Kelly L. Stratton · Principal Investigator

Saint Alphonsus Medical Center-Baker City

Baker City, Oregon, 97814

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Saint Charles Health System

Bend, Oregon, 97701

Recruiting
Site Public Contact · Contact
541-706-2909nosall@stcharleshealthcare.org
Charles W. Drescher · Principal Investigator

Clackamas Radiation Oncology Center

Clackamas, Oregon, 97015

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Charles W. Drescher · Principal Investigator

Providence Cancer Institute Clackamas Clinic

Clackamas, Oregon, 97015

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Charles W. Drescher · Principal Investigator

Bay Area Hospital

Coos Bay, Oregon, 97420

Recruiting
Site Public Contact · Contact
541-269-8392cherie.cox@bayareahospital.org
Charles W. Drescher · Principal Investigator

Providence Newberg Medical Center

Newberg, Oregon, 97132

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Charles W. Drescher · Principal Investigator

Saint Alphonsus Medical Center-Ontario

Ontario, Oregon, 97914

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Providence Willamette Falls Medical Center

Oregon City, Oregon, 97045

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Charles W. Drescher · Principal Investigator

Providence Portland Medical Center

Portland, Oregon, 97213

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Charles W. Drescher · Principal Investigator

Providence Saint Vincent Medical Center

Portland, Oregon, 97225

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Charles W. Drescher · Principal Investigator

Oregon Health and Science University

Portland, Oregon, 97239

Recruiting
Site Public Contact · Contact
503-494-1080trials@ohsu.edu
Alexandra O. Sokolova · Principal Investigator

Saint Charles Health System-Redmond

Redmond, Oregon, 97756

Recruiting
Site Public Contact · Contact
541-706-2909
Charles W. Drescher · Principal Investigator

Smilow Cancer Hospital Care Center - Westerly

Westerly, Rhode Island, 02891

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Joseph W. Kim · Principal Investigator

Providence Regional Cancer System-Aberdeen

Aberdeen, Washington, 98520

Recruiting
Site Public Contact · Contact
360-412-8958deidre.dillon@providence.org
Charles W. Drescher · Principal Investigator

PeaceHealth Saint Joseph Medical Center

Bellingham, Washington, 98225

Recruiting
Site Public Contact · Contact
360-788-8223
Charles W. Drescher · Principal Investigator

Harrison Medical Center

Bremerton, Washington, 98310

Recruiting
Site Public Contact · Contact
253-426-6882ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Providence Regional Cancer System-Centralia

Centralia, Washington, 98531

Recruiting
Site Public Contact · Contact
360-412-8958deidre.dillon@providence.org
Charles W. Drescher · Principal Investigator

Swedish Cancer Institute-Edmonds

Edmonds, Washington, 98026

Recruiting
Site Public Contact · Contact
206-215-3086PCRC-NCORP@Swedish.org
Charles W. Drescher · Principal Investigator

Providence Regional Cancer Partnership

Everett, Washington, 98201

Recruiting
Site Public Contact · Contact
425-261-3529marilyn.birchman@providence.org
Charles W. Drescher · Principal Investigator

Swedish Cancer Institute-Issaquah

Issaquah, Washington, 98029

Recruiting
Site Public Contact · Contact
206-215-3086PCRC-NCORP@Swedish.org
Charles W. Drescher · Principal Investigator

Kadlec Clinic Hematology and Oncology

Kennewick, Washington, 99336

Recruiting
Site Public Contact · Contact
509-783-4637research@kadlecmed.org
Charles W. Drescher · Principal Investigator

Providence Regional Cancer System-Lacey

Lacey, Washington, 98503

Recruiting
Site Public Contact · Contact
360-412-8958deidre.dillon@providence.org
Charles W. Drescher · Principal Investigator

PeaceHealth Saint John Medical Center

Longview, Washington, 98632

Recruiting
Site Public Contact · Contact
360-514-2016kmakin-bond@peacehealth.org
Charles W. Drescher · Principal Investigator

Swedish Medical Center-Ballard Campus

Seattle, Washington, 98107

Recruiting
Site Public Contact · Contact
206-215-3086PCRC-NCORP@Swedish.org
Charles W. Drescher · Principal Investigator

FHCC South Lake Union

Seattle, Washington, 98109

Recruiting
Site Public Contact · Contact
800-804-8824
Heather H. Cheng · Principal Investigator

Fred Hutchinson Cancer Research Center

Seattle, Washington, 98109

Recruiting
Site Public Contact · Contact
800-804-8824
Heather H. Cheng · Principal Investigator

Swedish Medical Center-Cherry Hill

Seattle, Washington, 98122-5711

Recruiting
Site Public Contact · Contact
206-215-3086PCRC-NCORP@Swedish.org
Charles W. Drescher · Principal Investigator

Swedish Medical Center-First Hill

Seattle, Washington, 98122

Recruiting
Site Public Contact · Contact
206-215-3086PCRC-NCORP@Swedish.org
Charles W. Drescher · Principal Investigator

University of Washington Medical Center - Montlake

Seattle, Washington, 98195

Recruiting
Site Public Contact · Contact
800-804-8824
Heather H. Cheng · Principal Investigator

PeaceHealth United General Medical Center

Sedro-Woolley, Washington, 98284

Recruiting
Site Public Contact · Contact
360-788-8238lkey@peacehealth.org
Charles W. Drescher · Principal Investigator

Providence Regional Cancer System-Shelton

Shelton, Washington, 98584

Recruiting
Site Public Contact · Contact
360-412-8958deidre.dillon@providence.org
Charles W. Drescher · Principal Investigator

PeaceHealth Southwest Medical Center

Vancouver, Washington, 98664

Recruiting
Site Public Contact · Contact
360-514-3940kmakin-bond@peacehealth.org
Charles W. Drescher · Principal Investigator

Providence Saint Mary Regional Cancer Center

Walla Walla, Washington, 99362

Recruiting
Site Public Contact · Contact
509-897-5993Cheryl.Dodd@providence.org
Charles W. Drescher · Principal Investigator

Providence Regional Cancer System-Yelm

Yelm, Washington, 98597

Recruiting
Site Public Contact · Contact
360-412-8958deidre.dillon@providence.org
Charles W. Drescher · Principal Investigator

Billings Clinic-Cody

Cody, Wyoming, 82414

Recruiting
Site Public Contact · Contact
800-996-2663research@billingsclinic.org
John M. Schallenkamp · Principal Investigator

Welch Cancer Center

Sheridan, Wyoming, 82801

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator