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RecruitingObservational

EXERT-C: Prospective Study of an EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer

NCT ID: NCT06083324Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)Last updated: 2025-02-21

Summary

This protocol seeks to analyze patient outcomes of the standard of care, monitored group exercise regimen of high-load resistance training and functional exercises with compound movements under close supervision on individuals who have been treated for cancer.

Arms & interventions

  • OtherDose escalated resistance training

    All individuals will be engaging in resistance training during and/or after their cancer treatment

Outcome measures

Primary

  • Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via bioimpedance analysis

    Measurement on bioimpedance analysis machine (Inbody 970)

    Time frame: 3 months

  • Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via ultrasound

    Measurement via ultrasound and calculation with Jackson-Pollack calculations

    Time frame: 3 months

  • Determine changes in muscle mass in pounds from before to after the nutrition and exercise regimen

    Measurement on bioimpedance analysis machine (Inbody 970)

    Time frame: 3 months

Secondary

  • Determine changes in overall score of functional movement screen (FMS) from before to after the nutrition and exercise regimen

    Time frame: 3 months

  • Determine changes in Y-balance score for each leg

    Time frame: 3 months

  • Determine changes in strength via load measured in pounds from before to after the nutrition and exercise regimen

    Time frame: 3 months

  • Determine changes in EQ-5D responses 1-5 and overall score from before to after the nutrition and exercise regimen

    Time frame: 3 months

Eligibility criteria

Sex: AllAge: 20 Years to 89 YearsHealthy volunteers: No
Inclusion Criteria: 1. Age 20-89 years 2. Women of child-bearing potential must verbally confirm lack of pregnancy prior to enrollment. They should also consent to use adequate contraception during the course of the study. 3. Participants must be determined capable of engaging in resistance training by exercise personnel and/or study PI 4. Participants must complete an assessment by EOC staff and be determined safe to engage in the workout regimen by the study exercise personnel. 5. Individuals not deemed safe to participate in the standard EOC exercise program will be referred to physical therapy or elsewhere Exclusion Criteria: 1\. Severe arthritic, joint, cardiovascular, or musculoskeletal condition that would interfere with exercise program

Study locations (1)

AHN CI Exercise Oncology and Resiliency Center

Pittsburgh, Pennsylvania, 15202

Recruiting
Colin E Champ, MD, CSCS · Contact
412-734-7605colin.champ@ahn.org
Chris Peluso, BS · Sub Investigator

References

  • Champ CE, Carpenter DJ, Diaz AK, Rosenberg J, Ackerson BG, Hyde PN. Resistance Training for Patients with Cancer: A Conceptual Framework for Maximizing Strength, Power, Functional Mobility, and Body Composition to Optimize Health and Outcomes. Sports Med. 2023 Jan;53(1):75-89. doi: 10.1007/s40279-022-01759-z. Epub 2022 Sep 29.(PubMed)