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RecruitingInterventional

Weighted Blanket Use in Oncology Patients to Reduce Anxiety

NCT ID: NCT06089408Sponsor: Ohio State University Comprehensive Cancer CenterLast updated: 2025-08-08

Summary

This clinical trial compares the effect of using weighted blankets versus regular blankets during first time infusions (e.g. chemotherapy, targeted therapy etc.) to decrease adverse side effects such as anxiety and distress in cancer (oncology) patients. Feeling safe, comforted, and grounded in the world are some of the benefits noted by individuals who use weighted blankets. Deep touch pressure (DTP) has been found to reduce symptoms of stress and anxiety and is defined as a sensation one feels when being hugged, squeezed, or held. DTP affects the nervous system by creating a calming effect which may lower stress and increase feelings of well-being. The use of weighted blankets may help to manage anxiety and distress during chemotherapy or immunotherapy infusions.

Detailed description

PRIMARY OBJECTIVE: I. To assess the efficacy of weighted blankets on anxiety in patients receiving infusion therapy. SECONDARY OBJECTIVE: I. To assess the efficacy of weighted blankets on distress in patients receiving infusion therapy. OUTLINE: Patients are randomized to 1 of 2 arms. ARM I: Patients use a weighted blanket for 30 minutes during the infusion appointment. ARM II: Patients use a regular blanket for 30 minutes per standard of care during the infusion appointment.

Arms & interventions

  • OtherBest Practice

    Use a regular blanket

  • OtherSupportive Care

    Use a weighted blanket

  • OtherSurvey Administration

    Ancillary studies

Outcome measures

Primary

  • Levels of anxiety using State Trait Anxiety Inventory (STAI) for Adults, short form

    To test for the effect of the weighted blanket, will fit a mixed model with the post-level of anxiety as the dependent variable and baseline values and treatment (standard or weighted blanket) as predictors. A random effect for patient will be fit to account for the possible correlation of within-patient repeated outcome measures. The models will control for patient gender and age.

    Time frame: At baseline and 30 minutes after use of either a standard or weighted blanket

Secondary

  • Levels of distress using NCCN Distress Thermometer

    Time frame: At baseline and 30 minutes after use of either a standard or weighted blanket

  • Qualitative change in levels of anxiety based on the baseline and 30 min post blanket use scores using State Trait Anxiety Inventory (STAI) for Adults, short form

    Time frame: At baseline and 30 minutes after use of either a standard or weighted blanket

  • Qualitative change in levels of distress based on the baseline and 30 min post blanket use scores using NCCN Distress Thermometer

    Time frame: At baseline and 30 minutes after use of either a standard or weighted blanket

Eligibility criteria

Sex: AllAge: 18 Years and olderHealthy volunteers: No
Inclusion Criteria: * Age 18 years of age and older * About to begin either targeted or cytotoxic chemotherapy * Able to comprehend and sign a consent form * Able to read and complete surveys * Alert and oriented Exclusion Criteria: * Currently using a weighted blanket at home * Non-English speaking * Peripheral neuropathy * Fibromyalgia * Open pressure ulcer * Recent surgical flap * Claustrophobic * Weight 45 kg or less

Study locations (1)

Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210

Recruiting
Allison De Villiers, MSN, RN, ONC · Contact
Allison De Villiers, MSN, RN, ONC · Principal Investigator
Weighted Blanket Use to Reduce Anxiety in Oncology Patients | Cancerify