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RecruitingInterventionalPhase 2/Phase 3

Randomized Phase II/III Trial of 2nd Line Nivolumab + Paclitaxel + Ramucirumab Versus Paclitaxel + Ramucirumab in Patients With PD-L1 CPS >/= 1 Advanced Gastric and Esophageal Adenocarcinoma (PARAMUNE)

NCT ID: NCT06203600Sponsor: National Cancer Institute (NCI)Last updated: 2026-06-17

Summary

This phase II/III trial compares the addition of nivolumab to the usual treatment of paclitaxel and ramucirumab to paclitaxel and ramucirumab alone in treating patients with gastric or esophageal adenocarcinoma that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced). A monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Ramucirumab is a monoclonal antibody that may prevent the growth of new blood vessels that tumors need to grow. Paclitaxel is in a class of medications called antimicrotubule agents. It stops cancer cells from growing and dividing and may kill them. Adding nivolumab to ramucirumab and paclitaxel may work better to treat patients with advanced stomach or esophageal cancer.

Detailed description

PRIMARY OBJECTIVES: I. To assess whether progression-free survival (PFS) is sufficiently improved in participants randomized to nivolumab + paclitaxel + ramucirumab compared to those randomized to paclitaxel + ramucirumab to warrant a phase III study with overall survival (OS) as the primary endpoint. (Phase II) II. To compare OS in participants randomized to nivolumab + paclitaxel + ramucirumab versus those randomized to paclitaxel + ramucirumab. (Phase III) SECONDARY OBJECTIVES: I. To compare PFS between those randomized to nivolumab + paclitaxel + ramucirumab versus those randomized to paclitaxel + ramucirumab. (Phase III) II. To compare OS between participants randomized to nivolumab + paclitaxel + ramucirumab compared to those randomized to paclitaxel + ramucirumab in the event that the trial is completed before the phase III portion. III. To compare the overall response rate (ORR, including confirmed and unconfirmed, complete, and partial response, according to Response Evaluation Criteria in Solid Tumors \[RECIST 1.1\] criteria) between those randomized to nivolumab + paclitaxel + ramucirumab compared to those randomized to paclitaxel + ramucirumab among participants with measurable disease. IV. To compare the overall disease control rate (DCR = ORR + stable disease) between those randomized to nivolumab + paclitaxel + ramucirumab compared to those randomized to paclitaxel + ramucirumab among participants with measurable disease. V. To evaluate the safety and tolerability of each treatment regimen. VI. To compare health-related quality of life (QOL) by treatment arm at 8 weeks after randomization, measured using the Functional Assessment of Cancer Therapy - Gastric (FACT-Ga) Trial Outcome Index (TOI). VII. To compare health-related QOL between treatment arms at 8 weeks after randomization using the FACT-Ga total score. VIII. To compare longitudinal changes in health-related QOL between treatment arms using FACT-Ga TOI up to 24 weeks after randomization. IX. To compare patient-reported symptoms using selected Patient-Reported Outcomes-Common Terminology Criteria for Adverse Events (PRO-CTCAE) items including gastrointestinal as well as constitutional symptoms of fatigue, anorexia, and weight loss between treatment arms. OUTLINE: Patients are randomized to 1 of 2 arms. ARM 1: Patients receive nivolumab intravenously (IV) over 30 minutes on day 1 of each cycle, ramucirumab IV over 30-60 minutes on days 1 and 15 of each cycle, and paclitaxel IV over 60 minutes on days 1, 8 and 15 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients undergo computed tomography (CT) scan and magnetic resonance imaging (MRI) throughout the study. Patients may also optionally undergo blood sample collection on study. ARM 2: Patients receive ramucirumab IV over 30-60 minutes on days 1 and 15 of each cycle and paclitaxel IV over 60 minutes on days 1, 8 and 15 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan and MRI throughout the study. Patients may also optionally undergo blood sample collection on study. After completion of study treatment, patients are followed up at 30, 60, 90 days and then every 6 months for up to 3 years.

Arms & interventions

  • ProcedureBiospecimen Collection

    Undergo optional blood sample collection

  • ProcedureComputed Tomography

    Undergo CT scan

  • ProcedureMagnetic Resonance Imaging

    Undergo MRI

  • BiologicalNivolumab

    Given IV

  • DrugPaclitaxel

    Given IV

  • OtherQuestionnaire Administration

    Ancillary studies

  • BiologicalRamucirumab

    Given IV

Outcome measures

Primary

  • Progression free survival (PFS) (Phase II)

    The distribution of PFS will be estimated using the method of Kaplan-Meier and compared using a 1-sided stratified log-rank test.

    Time frame: From date of randomization to date of first documentation of progression or symptomatic deterioration or death due to any cause, assessed up to 3 years

  • Overall survival (OS) (Phase III)

    The distribution of OS will be estimated using the method of Kaplan-Meier and compared using a 1-sided stratified log-rank test.

    Time frame: From date of randomization to date of death due to any cause, assessed up to 3 years

Secondary

  • Objective response rate (ORR)

    Time frame: Up to 3 years

  • Disease control rate (DCR)

    Time frame: Up to 3 years

  • Incidence of adverse events

    Time frame: Up to 3 years

Eligibility criteria

Sex: AllAge: 18 Years and olderHealthy volunteers: No
Inclusion Criteria: * Participants must have advanced or locally unresectable gastric, gastroesophageal junction or esophageal adenocarcinoma * Participants must have PD-L1 CPS (Combined Positive Score) ≥ 1. This test would have been performed as part of standard of care (SOC) pathology testing, using tissue obtained within two years prior to registration and collected prior to or after a frontline regimen * Participants must have a histologically confirmed diagnosis of microsatellite stable (MSS) and HER2 negative gastric, gastroesophageal junction, or esophageal adenocarcinoma * Participants must have documented unresectable and/or metastatic disease on CT or MRI imaging completed prior to registration. Imaging must have been completed within 28 days prior to registration for participants with measurable disease. CT scans or MRIs used to assess non-measurable disease must have been completed within 42 days prior to registration. All disease must be assessed and documented on the Baseline Tumor Assessment Form * Participants with treated brain metastases must have no evidence of progression on the follow-up brain imaging after central nervous system (CNS)-directed therapy. All treatment for brain metastases must have been completed at least 28 days prior to registration * Participants must have disease progression or intolerance to frontline standard of care (SOC) chemotherapy plus either nivolumab, pembrolizumab or any other PD-1 or PD-L1 inhibitor. Peri-operative chemotherapy plus nivolumab, pembrolizumab or any other PD-1 or PD-L1 inhibitor will count as one line if disease progression occurs while on the therapy or within 6 months of completing the chemotherapy plus nivolumab or pembrolizumab or other PD-1/PD-L1 inhibitor cycle * Participants must not have received more than one prior line of systemic therapy defined as chemotherapy plus either nivolumab, pembrolizumab, or any other PD-1 or PD-L1 inhibitor, in the stage IV or unresectable setting. Peri-operative or adjuvant nivoluamb or other PD-1/PD-L1 inhibitors would count as one prior line of systemic therapy if patients progressed while on nivolumab (or other PD-1/PD-L1 inhibitors) or within 6 months of stopping it * Note: Radiation or any other regional therapy options done to address local residual disease or metastatic disease would not count as a line of therapy. Maintenance therapy with a different form of fluoropyrimidine (i.e. switching from capecitabine to fluorouracil \[5FU\]) would not count as another line of therapy * Participants must not have a condition requiring systemic treatment with either corticosteroids (\> 10 mg daily prednisone equivalents) or other immunosuppressive medications within 14 days of registration. Inhaled or topical steroids and adrenal replacement doses \< 10 mg daily prednisone equivalents are permitted in the absence of active autoimmune disease. Participants are permitted to use topical, ocular, intra-articular, intranasal, and inhalational corticosteroids (with minimal systemic absorption). Physiologic replacement doses of systemic corticosteroids are permitted, even if \< 10 mg/day prednisone equivalents. A brief course of corticosteroids for prophylaxis (e.g., contrast dye allergy) or for treatment of non-autoimmune conditions (e.g., delayed-type hypersensitivity reaction caused by contact allergen) is permitted, as long as there has been a washout period for corticosteroids of ≥ 7 days prior to registration * Participants must not have prior significant immunotherapy related adverse events requiring permanent discontinuation of the immunotherapy agent including events like pneumonitis, myocarditis, renal failure, Guillain barre syndrome, or myasthenia gravis. Participants with endocrinopathy events leading or not to replacement steroids, thyroid hormone, insulin, or cortisol are eligible * Participants must not have received a live attenuated vaccination within 28 days prior to registration * Participants must not have had a major surgery within 28 days or subcutaneous venous access device placement within 7 days prior registration * Participants must have fully recovered from the effects of prior surgery in the opinion of the treating investigator. Any participants with postoperative bleeding complications or wound complications from a surgical procedure performed in the last eight weeks should be excluded * Participants must not have plans to undergo elective or planned major surgery during the clinical trial * Participants must not have active bleeding or prior history of gastrointestinal (GI) perforation, fistula or significant GI bleeding (requiring transfusion, endoscopic or surgical intervention) within 84 days prior to registration * Participants must not be planning to receive any concurrent chemotherapy, immunotherapy, investigational agents, biologic or hormonal therapy for cancer treatment while receiving treatment on this study * Participants must not have a history of a grade 3 or 4 allergic reaction attributed to humanized or human monoclonal antibody therapy * Participants must not have a history of grade 3 or 4 immunotherapy related toxicities with the exception of hormonal abnormalities like thyroiditis or thyroid derangements * Participants must be ≥ 18 years old * Participants must have Zubrod Performance Status of 0-2 * Participants must have a complete medical history and physical exam within 28 days prior to registration * Leukocytes ≥ 2 x 10\^3/uL (within 28 days prior to registration) * Absolute neutrophil count ≥ 1.2 x 10\^3/uL (within 28 days prior to registration) * Hemoglobin ≥ 9.0 g/dL (within 28 days prior to registration) * Platelets ≥ 100 x 10\^3/uL (within 28 days prior to registration) * Total bilirubin ≤ 1.5 x institutional upper limit of normal (ULN) (within 28 days prior to registration) unless history of Gilbert's disease. Participants with history of Gilbert's disease must have total bilirubin ≤ 5 x institutional ULN * Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) ≤ 3 × institutional ULN (within 28 days prior to registration) (unless liver metastases are present, in which case they must be ≤ 5 x ULN) * Participants must have a calculated creatinine clearance ≥ 40 mL/min using the following Cockcroft-Gault Formula. This specimen must have been drawn and processed within 28 days prior to registration * Participants' urinary protein must be ≤ 1+ on dipstick or routine urinalysis (UA) within 28 days of registration. Random analysis of urine protein with a normal value is sufficient. If urine dipstick or routine analysis indicated proteinuria ≥ 2+, then a 24-hour urine is to be collected and demonstrate \< 1000 mg of protein in 24 hours to allow participation in the study * Participants must have adequate cardiac function. Participants with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, must have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, participants must be class 2 or better * Participants must have recovered to baseline or \< grade 2 CTCAE version (v) 5.0 from toxicities related to any prior treatments, unless AE(s) are clinically stable on supportive therapy * Participants must not have experienced arterial thromboembolic events, including but not limited to myocardial infarction, transient ischemic attack, cerebrovascular accident, or unstable angina, within 6 months prior to registration * Participants must not have uncontrolled blood pressure within 28 days prior to registration as determined by the treating investigator * Participants with known human immunodeficiency virus (HIV)-infection must be on effective anti-retroviral therapy at registration and have undetectable viral load on the most recent test results obtained within 6 months prior to registration * Participants with evidence of chronic hepatitis B virus (HBV) infection must have undetectable HBV viral load while on suppressive therapy on the most recent test results obtained within 6 months prior to registration, if indicated * Participants with a history of hepatitis C virus (HCV) infection must have been treated and cured. Participants currently being treated for HCV infection must have undetectable HCV viral load on the most recent test results obtained within 6 months prior to registration, if indicated * Participants must not have a prior or concurrent malignancy whose natural history or treatment (in the opinion of the treating physician) has the potential to interfere with the safety or efficacy assessment of the investigational regimen * Participants must not be pregnant or nursing (nursing includes breast milk fed to an infant by any means, including from the breast, milk expressed by hand, or pumped). Individuals who are of reproductive potential must have agreed to use an effective contraceptive method with details provided as a part of the consent process. A person who has had menses at any time in the preceding 12 consecutive months or who has semen likely to contain sperm is considered to be of "reproductive potential." In addition to routine contraceptive methods, "effective contraception" also includes refraining from sexual activity that might result in pregnancy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) including hysterectomy, bilateral oophorectomy, bilateral tubal ligation/occlusion, and vasectomy with testing showing no sperm in the semen * Participants must not have a history of inflammatory bowel disease, (including ulcerative colitis and Crohn's disease), symptomatic autoimmune disease (e.g., rheumatoid arthritis, systemic progressive sclerosis \[scleroderma\], systemic lupus erythematosus, autoimmune vasculitis \[e.g., Wegener's Granulomatosis\]); CNS or motor neuropathy considered of autoimmune origin (e.g., Guillain-Barre Syndrome and myasthenia gravis, multiple sclerosis). Note: Participants with Graves' disease will be allowed * Participants must not have a history of pneumonitis that has required oral or IV steroids within the last 12 months prior to registration * Participants must be offered the opportunity to participate in specimen banking. With participant consent, specimens must be collected and submitted via the Southwest Oncology Group (SWOG) Specimen Tracking System * Participants who can complete patient reported outcomes (FACT-Ga and PRO-CTCAE) questionnaires in English or Spanish must participate in the quality of life studies * Participants must be informed of the investigational nature of this study and must sign and give informed consent in accordance with institutional and federal guidelines. For participants with impaired decision-making capabilities, legally authorized representatives may sign and give informed consent on behalf of study participants in accordance with applicable federal, local, and Central Institutional Review Board (CIRB) regulations

Study locations (372)

Baptist Health Medical Center - Little Rock

Little Rock, Arkansas, 72205

Recruiting
Site Public Contact · Contact
501-202-4715
Rangaswamy Govindarajan · Principal Investigator

University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72205

Recruiting
Site Public Contact · Contact
501-686-8274
Rangaswamy Govindarajan · Principal Investigator

Kaiser Permanente-Anaheim

Anaheim, California, 92806

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Gary L. Buchschacher · Principal Investigator

Kaiser Permanente-Baldwin Park

Baldwin Park, California, 91706

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Gary L. Buchschacher · Principal Investigator

Kaiser Permanente-Bellflower

Bellflower, California, 90706

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Gary L. Buchschacher · Principal Investigator

Tower Cancer Research Foundation

Beverly Hills, California, 90211

Recruiting
Site Public Contact · Contact
towercancerresearch@toweroncology.com
Jun Gong · Principal Investigator

Kaiser Permanente Dublin

Dublin, California, 94568

Recruiting
Site Public Contact · Contact
877-642-4691
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente-Fontana

Fontana, California, 92335

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Gary L. Buchschacher · Principal Investigator

Kaiser Permanente-Fremont

Fremont, California, 94538

Recruiting
Site Public Contact · Contact
877-642-4691Kpoct@kp.org
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente Fresno Orchard Plaza

Fresno, California, 93720

Recruiting
Site Public Contact · Contact
833-574-2273
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente-Fresno

Fresno, California, 93720

Recruiting
Site Public Contact · Contact
877-642-4691Kpoct@kp.org
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente South Bay

Harbor City, California, 90710

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Gary L. Buchschacher · Principal Investigator

Kaiser Permanente-Irvine

Irvine, California, 92618

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Gary L. Buchschacher · Principal Investigator

UC San Diego Moores Cancer Center

La Jolla, California, 92093

Recruiting
Site Public Contact · Contact
858-822-5354cancercto@ucsd.edu
Aaron Miller · Principal Investigator

Keck Medicine of USC Koreatown

Los Angeles, California, 90020

Recruiting
Site Public Contact · Contact
213-388-0908
Syma Iqbal · Principal Investigator

Kaiser Permanente Los Angeles Medical Center

Los Angeles, California, 90027

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Gary L. Buchschacher · Principal Investigator

Los Angeles General Medical Center

Los Angeles, California, 90033

Recruiting
Site Public Contact · Contact
323-865-0451uscnorrisinfo@med.usc.edu
Syma Iqbal · Principal Investigator

USC / Norris Comprehensive Cancer Center

Los Angeles, California, 90033

Recruiting
Site Public Contact · Contact
323-865-0451
Syma Iqbal · Principal Investigator

Kaiser Permanente West Los Angeles

Los Angeles, California, 90034

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Gary L. Buchschacher · Principal Investigator

Cedars-Sinai Medical Center

Los Angeles, California, 90048

Recruiting
Site Public Contact · Contact
310-423-2133Cancer.trial.info@cshs.org
Jun Gong · Principal Investigator

Kaiser Permanente- Modesto MOB II

Modesto, California, 95356

Recruiting
Site Public Contact · Contact
877-642-4691
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente-Modesto

Modesto, California, 95356

Recruiting
Site Public Contact · Contact
877-642-4691Kpoct@kp.org
Tilak K. Sundaresan · Principal Investigator

USC Norris Oncology/Hematology-Newport Beach

Newport Beach, California, 92663

Recruiting
Site Public Contact · Contact
323-865-0451
Syma Iqbal · Principal Investigator

Kaiser Permanente-Oakland

Oakland, California, 94611

Recruiting
Site Public Contact · Contact
877-642-4691Kpoct@kp.org
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente-Ontario

Ontario, California, 91761

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Gary L. Buchschacher · Principal Investigator

Kaiser Permanente - Panorama City

Panorama City, California, 91402

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Gary L. Buchschacher · Principal Investigator

Kaiser Permanente-Riverside

Riverside, California, 92505

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Gary L. Buchschacher · Principal Investigator

Kaiser Permanente-Roseville

Roseville, California, 95661

Recruiting
Site Public Contact · Contact
877-642-4691Kpoct@kp.org
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente Downtown Commons

Sacramento, California, 95814

Recruiting
Site Public Contact · Contact
877-642-4691kpoct@kp.org
Tilak K. Sundaresan · Principal Investigator

University of California Davis Comprehensive Cancer Center

Sacramento, California, 95817

Active Not Recruiting

Kaiser Permanente-South Sacramento

Sacramento, California, 95823

Recruiting
Site Public Contact · Contact
877-642-4691Kpoct@kp.org
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente-San Diego Zion

San Diego, California, 92120

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Gary L. Buchschacher · Principal Investigator

Kaiser Permanente-San Francisco

San Francisco, California, 94115

Recruiting
Site Public Contact · Contact
877-642-4691Kpoct@kp.org
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente-Santa Teresa-San Jose

San Jose, California, 95119

Recruiting
Site Public Contact · Contact
877-642-4691Kpoct@kp.org
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente San Leandro

San Leandro, California, 94577

Recruiting
Site Public Contact · Contact
877-642-4691Kpoct@kp.org
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente-San Marcos

San Marcos, California, 92078

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Gary L. Buchschacher · Principal Investigator

Kaiser San Rafael-Gallinas

San Rafael, California, 94903

Recruiting
Site Public Contact · Contact
877-642-4691Kpoct@kp.org
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente Medical Center - Santa Clara

Santa Clara, California, 95051

Recruiting
Site Public Contact · Contact
877-642-4691Kpoct@kp.org
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente-Santa Rosa

Santa Rosa, California, 95403

Recruiting
Site Public Contact · Contact
877-642-4691Kpoct@kp.org
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente-South San Francisco

South San Francisco, California, 94080

Recruiting
Site Public Contact · Contact
877-642-4691Kpoct@kp.org
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente-Vallejo

Vallejo, California, 94589

Recruiting
Site Public Contact · Contact
877-642-4691Kpoct@kp.org
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente-Walnut Creek

Walnut Creek, California, 94596

Recruiting
Site Public Contact · Contact
877-642-4691Kpoct@kp.org
Tilak K. Sundaresan · Principal Investigator

Kaiser Permanente-Woodland Hills

Woodland Hills, California, 91367

Recruiting
Site Public Contact · Contact
800-398-3996clinical.trials@kp.org
Gary L. Buchschacher · Principal Investigator

UCHealth Memorial Hospital Central

Colorado Springs, Colorado, 80909

Recruiting
Site Public Contact · Contact
719-365-2406
Shin Yin Lee · Principal Investigator

Memorial Hospital North

Colorado Springs, Colorado, 80920

Recruiting
Site Public Contact · Contact
719-364-6700
Shin Yin Lee · Principal Investigator

Poudre Valley Hospital

Fort Collins, Colorado, 80524

Recruiting
Site Public Contact · Contact
970-297-6150
Shin Yin Lee · Principal Investigator

Cancer Care and Hematology-Fort Collins

Fort Collins, Colorado, 80528

Recruiting
Site Public Contact · Contact
protocols@swog.org
Shin Yin Lee · Principal Investigator

UCHealth Greeley Hospital

Greeley, Colorado, 80631

Recruiting
Site Public Contact · Contact
protocols@swog.org
Shin Yin Lee · Principal Investigator

Medical Center of the Rockies

Loveland, Colorado, 80538

Recruiting
Site Public Contact · Contact
970-203-7083
Shin Yin Lee · Principal Investigator

Smilow Cancer Hospital-Derby Care Center

Derby, Connecticut, 06418

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Yifei Zhang · Principal Investigator

Smilow Cancer Hospital Care Center-Fairfield

Fairfield, Connecticut, 06824

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Yifei Zhang · Principal Investigator

Smilow Cancer Hospital Care Center at Glastonbury

Glastonbury, Connecticut, 06033

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Yifei Zhang · Principal Investigator

Smilow Cancer Hospital Care Center at Greenwich

Greenwich, Connecticut, 06830

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Yifei Zhang · Principal Investigator

Smilow Cancer Hospital Care Center - Guilford

Guilford, Connecticut, 06437

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Yifei Zhang · Principal Investigator

Smilow Cancer Hospital Care Center at Saint Francis

Hartford, Connecticut, 06105

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Yifei Zhang · Principal Investigator

Yale University

New Haven, Connecticut, 06520

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Yifei Zhang · Principal Investigator

Yale-New Haven Hospital North Haven Medical Center

North Haven, Connecticut, 06473

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Yifei Zhang · Principal Investigator

Smilow Cancer Hospital Care Center at Long Ridge

Stamford, Connecticut, 06902

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Yifei Zhang · Principal Investigator

Smilow Cancer Hospital-Torrington Care Center

Torrington, Connecticut, 06790

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Yifei Zhang · Principal Investigator

Smilow Cancer Hospital Care Center-Trumbull

Trumbull, Connecticut, 06611

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Yifei Zhang · Principal Investigator

Smilow Cancer Hospital-Waterbury Care Center

Waterbury, Connecticut, 06708

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Yifei Zhang · Principal Investigator

Smilow Cancer Hospital Care Center - Waterford

Waterford, Connecticut, 06385

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Yifei Zhang · Principal Investigator

Beebe South Coastal Health Campus

Millville, Delaware, 19967

Recruiting
Site Public Contact · Contact
302-291-6730research@beebehealthcare.org
Gregory A. Masters · Principal Investigator

Helen F Graham Cancer Center

Newark, Delaware, 19713

Recruiting
Site Public Contact · Contact
302-623-4450lbarone@christianacare.org
Gregory A. Masters · Principal Investigator

Medical Oncology Hematology Consultants PA

Newark, Delaware, 19713

Recruiting
Site Public Contact · Contact
302-623-4450lbarone@christianacare.org
Gregory A. Masters · Principal Investigator

Beebe Health Campus

Rehoboth Beach, Delaware, 19971

Recruiting
Site Public Contact · Contact
302-291-6730research@beebehealthcare.org
Gregory A. Masters · Principal Investigator

MedStar Georgetown University Hospital

Washington D.C., District of Columbia, 20007

Recruiting
Site Public Contact · Contact
202-444-2223
Reetu Mukherji · Principal Investigator

AdventHealth Orlando

Orlando, Florida, 32803

Recruiting
Site Public Contact · Contact
407-303-2090FH.Cancer.Research@flhosp.org
Mohamedtaki A. Tejani · Principal Investigator

Emory University Hospital Midtown

Atlanta, Georgia, 30308

Recruiting
Site Public Contact · Contact
888-946-7447
Oluwadunni Emiloju · Principal Investigator

Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia, 30322

Recruiting
Site Public Contact · Contact
404-778-1868
Oluwadunni Emiloju · Principal Investigator

Emory Saint Joseph's Hospital

Atlanta, Georgia, 30342

Recruiting
Site Public Contact · Contact
404-851-7115
Oluwadunni Emiloju · Principal Investigator

Emory Decatur Hospital

Decatur, Georgia, 30033

Recruiting
Site Public Contact · Contact
440-778-1868clinicaltrialsoncology@dekalbmedical.org
Oluwadunni Emiloju · Principal Investigator

Emory Johns Creek Hospital

Johns Creek, Georgia, 30097

Recruiting
Site Public Contact · Contact
404-778-5714m.lisa.hwang@emory.edu
Oluwadunni Emiloju · Principal Investigator

Hawaii Cancer Care Inc - Waterfront Plaza

Honolulu, Hawaii, 96813

Recruiting
Site Public Contact · Contact
808-524-6115i.webster@hawaiicancercare.com
Elizabeth S. Nakasone · Principal Investigator

Queen's Cancer Cenrer - POB I

Honolulu, Hawaii, 96813

Recruiting
Site Public Contact · Contact
808-532-0315
Elizabeth S. Nakasone · Principal Investigator

Queen's Medical Center

Honolulu, Hawaii, 96813

Recruiting
Site Public Contact · Contact
808-545-8548
Elizabeth S. Nakasone · Principal Investigator

Straub Clinic and Hospital

Honolulu, Hawaii, 96813

Recruiting
Site Public Contact · Contact
808-522-4333
Elizabeth S. Nakasone · Principal Investigator

Queen's Cancer Center - Kuakini

Honolulu, Hawaii, 96817

Recruiting
Site Public Contact · Contact
808-531-8521
Elizabeth S. Nakasone · Principal Investigator

Kaiser Permanente Moanalua Medical Center

Honolulu, Hawaii, 96819

Recruiting
Site Public Contact · Contact
808-432-5195shelley.a.clark@kp.org
Tilak K. Sundaresan · Principal Investigator

Kapiolani Medical Center for Women and Children

Honolulu, Hawaii, 96826

Recruiting
Site Public Contact · Contact
808-983-6090
Elizabeth S. Nakasone · Principal Investigator

Hawaii Cancer Care - Westridge

‘Aiea, Hawaii, 96701

Recruiting
Site Public Contact · Contact
808-539-2273info@hawaiicancercare.com
Elizabeth S. Nakasone · Principal Investigator

Pali Momi Medical Center

‘Aiea, Hawaii, 96701

Recruiting
Site Public Contact · Contact
808-486-6000
Elizabeth S. Nakasone · Principal Investigator

The Queen's Medical Center - West Oahu

‘Ewa Beach, Hawaii, 96706

Recruiting
Site Public Contact · Contact
rohta@queens.org
Elizabeth S. Nakasone · Principal Investigator

Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706

Recruiting
Site Public Contact · Contact
734-712-3671stephanie.couch@stjoeshealth.org
Tareq Al baghdadi · Principal Investigator

Saint Alphonsus Cancer Care Center-Caldwell

Caldwell, Idaho, 83605

Recruiting
Site Public Contact · Contact
734-712-3671stephanie.couch@stjoeshealth.org
Tareq Al baghdadi · Principal Investigator

Kootenai Health - Coeur d'Alene

Coeur d'Alene, Idaho, 83814

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Saint Alphonsus Cancer Care Center-Nampa

Nampa, Idaho, 83687

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
Tareq Al baghdadi · Principal Investigator

Kootenai Clinic Cancer Services - Post Falls

Post Falls, Idaho, 83854

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Kootenai Clinic Cancer Services - Sandpoint

Sandpoint, Idaho, 83864

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Rush-Copley Medical Center

Aurora, Illinois, 60504

Recruiting
Site Public Contact · Contact
630-978-6212RCMC_Cancer_Research@rush.edu
Suparna Mantha · Principal Investigator

Advocate Outpatient Center - Aurora

Aurora, Illinois, 60506

Recruiting
Site Public Contact · Contact
ncorp@aah.org
Edward S. James · Principal Investigator

Advocate Good Shepherd Hospital

Barrington, Illinois, 60010

Recruiting
Site Public Contact · Contact
847-842-4847
Edward S. James · Principal Investigator

Illinois CancerCare-Bloomington

Bloomington, Illinois, 61704

Suspended

Illinois CancerCare-Canton

Canton, Illinois, 61520

Suspended

Illinois CancerCare-Carthage

Carthage, Illinois, 62321

Suspended

Northwestern University

Chicago, Illinois, 60611

Recruiting
Site Public Contact · Contact
312-695-1301cancer@northwestern.edu
Aparna Kalyan · Principal Investigator

University of Illinois

Chicago, Illinois, 60612

Recruiting
Site Public Contact · Contact
312-355-3046
Yolande Chen · Principal Investigator

Swedish Covenant Hospital

Chicago, Illinois, 60625

Recruiting
Site Public Contact · Contact
773-878-8200
Lauren A. Wiebe · Principal Investigator

University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637

Active Not Recruiting

Advocate Illinois Masonic Medical Center

Chicago, Illinois, 60657

Recruiting
Site Public Contact · Contact
773-296-5360
Edward S. James · Principal Investigator

AMG Crystal Lake - Oncology

Crystal Lake, Illinois, 60014

Recruiting
Site Public Contact · Contact
630-929-6129advocateresearch@advocate.com
Edward S. James · Principal Investigator

Carle at The Riverfront

Danville, Illinois, 61832

Recruiting
Site Public Contact · Contact
800-446-5532Research@Carle.com
Suparna Mantha · Principal Investigator

Cancer Care Specialists of Illinois - Decatur

Decatur, Illinois, 62526

Recruiting
Site Public Contact · Contact
217-876-4762morganthaler.jodi@mhsil.com
Bryan A. Faller · Principal Investigator

Decatur Memorial Hospital

Decatur, Illinois, 62526

Recruiting
Site Public Contact · Contact
217-876-4762morganthaler.jodi@mhsil.com
Bryan A. Faller · Principal Investigator

Northwestern Medicine Cancer Center Kishwaukee

DeKalb, Illinois, 60115

Recruiting
Site Public Contact · Contact
630-352-5360Donald.Smith3@nm.org
Aparna Kalyan · Principal Investigator

Illinois CancerCare-Dixon

Dixon, Illinois, 61021

Suspended

Advocate Good Samaritan Hospital

Downers Grove, Illinois, 60515

Recruiting
Site Public Contact · Contact
630-275-1270Barbara.barhamand@advocatehealth.com
Edward S. James · Principal Investigator

Carle Physician Group-Effingham

Effingham, Illinois, 62401

Recruiting
Site Public Contact · Contact
800-446-5532Research@carle.com
Suparna Mantha · Principal Investigator

Crossroads Cancer Center

Effingham, Illinois, 62401

Recruiting
Site Public Contact · Contact
217-876-4762morganthaler.jodi@mhsil.com
Bryan A. Faller · Principal Investigator

Advocate Sherman Hospital

Elgin, Illinois, 60123

Recruiting
Site Public Contact · Contact
847-429-2907
Edward S. James · Principal Investigator

Illinois CancerCare-Eureka

Eureka, Illinois, 61530

Suspended

NorthShore University HealthSystem-Evanston Hospital

Evanston, Illinois, 60201

Recruiting
Site Public Contact · Contact
847-570-2109
Lauren A. Wiebe · Principal Investigator

Illinois CancerCare-Galesburg

Galesburg, Illinois, 61401

Suspended

Northwestern Medicine Cancer Center Delnor

Geneva, Illinois, 60134

Recruiting
Site Public Contact · Contact
630-352-5360Donald.Smith3@nm.org
Aparna Kalyan · Principal Investigator

NorthShore University HealthSystem-Glenbrook Hospital

Glenview, Illinois, 60026

Recruiting
Site Public Contact · Contact
847-570-2109
Lauren A. Wiebe · Principal Investigator

Northwestern Medicine Glenview Outpatient Center

Glenview, Illinois, 60026

Recruiting
Site Public Contact · Contact
312-695-1102
Aparna Kalyan · Principal Investigator

Northwestern Medicine Grayslake Outpatient Center

Grayslake, Illinois, 60030

Recruiting
Site Public Contact · Contact
312-695-1102
Aparna Kalyan · Principal Investigator

Ingalls Memorial Hospital

Harvey, Illinois, 60426

Active Not Recruiting

Advocate South Suburban Hospital

Hazel Crest, Illinois, 60429

Recruiting
Site Public Contact · Contact
708-799-9995
Edward S. James · Principal Investigator

NorthShore University HealthSystem-Highland Park Hospital

Highland Park, Illinois, 60035

Recruiting
Site Public Contact · Contact
847-570-2109
Lauren A. Wiebe · Principal Investigator

Illinois CancerCare-Kewanee Clinic

Kewanee, Illinois, 61443

Suspended

Northwestern Medicine Lake Forest Hospital

Lake Forest, Illinois, 60045

Recruiting
Site Public Contact · Contact
cancertrials@northwestern.edu
Aparna Kalyan · Principal Investigator

AMG Libertyville - Oncology

Libertyville, Illinois, 60048

Recruiting
Site Public Contact · Contact
630-929-6129advocateresearch@advocatehealth.com
Edward S. James · Principal Investigator

Condell Memorial Hospital

Libertyville, Illinois, 60048

Recruiting
Site Public Contact · Contact
630-929-6129advocateresearch@advocatehealth.com
Edward S. James · Principal Investigator

Illinois CancerCare-Macomb

Macomb, Illinois, 61455

Suspended

Carle Physician Group-Mattoon/Charleston

Mattoon, Illinois, 61938

Recruiting
Site Public Contact · Contact
800-446-5532Research@carle.com
Suparna Mantha · Principal Investigator

UC Comprehensive Cancer Center at Silver Cross

New Lenox, Illinois, 60451

Active Not Recruiting

Cancer Care Center of O'Fallon

O'Fallon, Illinois, 62269

Recruiting
Site Public Contact · Contact
217-876-4762morganthaler.jodi@mhsil.com
Bryan A. Faller · Principal Investigator

Northwestern Medicine Oak Brook

Oak Brook, Illinois, 60523

Recruiting
Site Public Contact · Contact
nctnprogram_rhlccc@northwestern.edu
Aparna Kalyan · Principal Investigator

Advocate Christ Medical Center

Oak Lawn, Illinois, 60453-2699

Recruiting
Site Public Contact · Contact
800-323-8622
Edward S. James · Principal Investigator

Northwestern Medicine Orland Park

Orland Park, Illinois, 60462

Recruiting
Site Public Contact · Contact
nctnprogram_rhlccc@northwestern.edu
Aparna Kalyan · Principal Investigator

University of Chicago Medicine-Orland Park

Orland Park, Illinois, 60462

Active Not Recruiting

Illinois CancerCare-Ottawa Clinic

Ottawa, Illinois, 61350

Suspended

Advocate Lutheran General Hospital

Park Ridge, Illinois, 60068

Recruiting
Site Public Contact · Contact
847-384-3621
Edward S. James · Principal Investigator

Illinois CancerCare-Pekin

Pekin, Illinois, 61554

Suspended

Illinois CancerCare-Peoria

Peoria, Illinois, 61615

Suspended

Illinois CancerCare-Peru

Peru, Illinois, 61354

Suspended

Illinois CancerCare-Princeton

Princeton, Illinois, 61356

Suspended

Mercyhealth Cancer Institute - Rockford

Rockford, Illinois, 61114

Recruiting
Site Public Contact · Contact
815-971-5858oncologyclinicaltrials@mhemail.org
Mayur Narkhede · Principal Investigator

UW Health Carbone Cancer Center Rockford

Rockford, Illinois, 61114

Recruiting
Site Public Contact · Contact
779-696-9378lkline@uwhealth.org
Fahrettin Covut · Principal Investigator

Memorial Hospital East

Shiloh, Illinois, 62269

Recruiting
Site Public Contact · Contact
314-747-9912dschwab@wustl.edu
Patrick Grierson · Principal Investigator

Southern Illinois University School of Medicine

Springfield, Illinois, 62702

Recruiting
Site Public Contact · Contact
217-545-7929
Bryan A. Faller · Principal Investigator

Springfield Clinic

Springfield, Illinois, 62702

Recruiting
Site Public Contact · Contact
800-444-7541
Bryan A. Faller · Principal Investigator

Springfield Memorial Hospital

Springfield, Illinois, 62781

Recruiting
Site Public Contact · Contact
217-528-7541pallante.beth@mhsil.com
Bryan A. Faller · Principal Investigator

Carle Cancer Center

Urbana, Illinois, 61801

Recruiting
Site Public Contact · Contact
800-446-5532Research@carle.com
Suparna Mantha · Principal Investigator

Northwestern Medicine Cancer Center Warrenville

Warrenville, Illinois, 60555

Recruiting
Site Public Contact · Contact
630-352-5360Donald.Smith3@nm.org
Aparna Kalyan · Principal Investigator

Illinois CancerCare - Washington

Washington, Illinois, 61571

Suspended

Northwest Cancer Center - Crown Point

Crown Point, Indiana, 46307

Recruiting
Site Public Contact · Contact
219-836-6879CancerResearch@powershealth.org
Suparna Mantha · Principal Investigator

UChicago Medicine Northwest Indiana

Crown Point, Indiana, 46307

Active Not Recruiting

Northwest Oncology LLC

Dyer, Indiana, 46311

Recruiting
Site Public Contact · Contact
219-924-8178
Suparna Mantha · Principal Investigator

Northwest Cancer Center - Hobart

Hobart, Indiana, 46342

Recruiting
Site Public Contact · Contact
219-947-1795
Suparna Mantha · Principal Investigator

Saint Mary Medical Center

Hobart, Indiana, 46342

Recruiting
Site Public Contact · Contact
219-836-6875CancerResearch@COMHS.org
Suparna Mantha · Principal Investigator

Saint Catherine Hospital

Indianapolis, Indiana, 46312

Recruiting
Site Public Contact · Contact
protocols@swog.org
Suparna Mantha · Principal Investigator

The Community Hospital

Munster, Indiana, 46321

Recruiting
Site Public Contact · Contact
219-836-3349
Suparna Mantha · Principal Investigator

Women's Diagnostic Center - Munster

Munster, Indiana, 46321

Recruiting
Site Public Contact · Contact
219-934-8869mnicholson@comhs.org
Suparna Mantha · Principal Investigator

Northwest Cancer Center - Valparaiso

Valparaiso, Indiana, 46383

Recruiting
Site Public Contact · Contact
219-836-6875CancerResearch@COMHS.org
Suparna Mantha · Principal Investigator

UI Health Care Mission Cancer and Blood - Ankeny Clinic

Ankeny, Iowa, 50023

Recruiting
Site Public Contact · Contact
515-241-3305
Seema Harichand-Herdt · Principal Investigator

Saint Anthony Regional Hospital

Carroll, Iowa, 51401

Recruiting
Site Public Contact · Contact
515-689-7658sbenson@iora.org
Seema Harichand-Herdt · Principal Investigator

Mercy Hospital

Cedar Rapids, Iowa, 52403

Recruiting
Site Public Contact · Contact
319-365-4673
Deborah W. Wilbur · Principal Investigator

Oncology Associates at Mercy Medical Center

Cedar Rapids, Iowa, 52403

Recruiting
Site Public Contact · Contact
319-363-2690
Deborah W. Wilbur · Principal Investigator

UI Health Care Mission Cancer and Blood - West Des Moines Clinic

Clive, Iowa, 50325

Recruiting
Site Public Contact · Contact
515-241-3305
Seema Harichand-Herdt · Principal Investigator

Iowa Methodist Medical Center

Des Moines, Iowa, 50309

Recruiting
Site Public Contact · Contact
515-241-6727
Seema Harichand-Herdt · Principal Investigator

UI Health Care Mission Cancer and Blood - Des Moines Clinic

Des Moines, Iowa, 50309

Recruiting
Site Public Contact · Contact
515-241-3305
Seema Harichand-Herdt · Principal Investigator

Broadlawns Medical Center

Des Moines, Iowa, 50314

Recruiting
Site Public Contact · Contact
515-282-2200
Seema Harichand-Herdt · Principal Investigator

UI Health Care Mission Cancer and Blood - Laurel Clinic

Des Moines, Iowa, 50314

Recruiting
Site Public Contact · Contact
515-241-3305
Seema Harichand-Herdt · Principal Investigator

UI Healthcare Mission Cancer and Blood - Fort Dodge

Fort Dodge, Iowa, 50501

Recruiting
Site Public Contact · Contact
515-282-2921trials@missioncancer.com
Seema Harichand-Herdt · Principal Investigator

UI Health Care Mission Cancer and Blood - Waukee Clinic

Waukee, Iowa, 50263

Recruiting
Site Public Contact · Contact
515-241-3305
Seema Harichand-Herdt · Principal Investigator

HaysMed

Hays, Kansas, 67601

Recruiting
Site Public Contact · Contact
785-623-5774
Gary C. Doolittle · Principal Investigator

Lawrence Memorial Hospital

Lawrence, Kansas, 66044

Suspended

The University of Kansas Cancer Center - Olathe

Olathe, Kansas, 66061

Recruiting
Site Public Contact · Contact
913-588-1569OlatheCCResearch@kumc.edu
Gary C. Doolittle · Principal Investigator

Salina Regional Health Center

Salina, Kansas, 67401

Recruiting
Site Public Contact · Contact
785-452-7038mleepers@srhc.com
Gary C. Doolittle · Principal Investigator

University of Kansas Health System Saint Francis Campus

Topeka, Kansas, 66606

Recruiting
Site Public Contact · Contact
785-295-8000
Gary C. Doolittle · Principal Investigator

Saint Joseph Hospital East

Lexington, Kentucky, 40509

Recruiting
Site Public Contact · Contact
720-874-1881ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Ochsner Hematology Oncology North Shore - Covington (West Region)

Covington, Louisiana, 70433

Recruiting
Site Public Contact · Contact
985-809-5668Cheryl.kesler@ochsner.org
Jonathan D. Mizrahi · Principal Investigator

Ochsner Medical Center Jefferson

New Orleans, Louisiana, 70121

Recruiting
Site Public Contact · Contact
504-842-8084Elisemarie.curry@ochsner.org
Jonathan D. Mizrahi · Principal Investigator

UPMC Western Maryland

Cumberland, Maryland, 21502

Recruiting
Site Public Contact · Contact
240-964-1400
Anwaar Saeed · Principal Investigator

Trinity Health Saint Joseph Mercy Hospital Ann Arbor

Ann Arbor, Michigan, 48106

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Tareq Al baghdadi · Principal Investigator

Trinity Health IHA Medical Group Hematology Oncology - Brighton

Brighton, Michigan, 48114

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Tareq Al baghdadi · Principal Investigator

Trinity Health Medical Center - Brighton

Brighton, Michigan, 48114

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Tareq Al baghdadi · Principal Investigator

Henry Ford Cancer Institute-Downriver

Brownstown, Michigan, 48183

Recruiting
Site Public Contact · Contact
313-916-3721CTOResearch@hfhs.org
Gazala Khan · Principal Investigator

Trinity Health IHA Medical Group Hematology Oncology - Canton

Canton, Michigan, 48188

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Tareq Al baghdadi · Principal Investigator

Trinity Health Medical Center - Canton

Canton, Michigan, 48188

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Tareq Al baghdadi · Principal Investigator

Chelsea Hospital

Chelsea, Michigan, 48118

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Tareq Al baghdadi · Principal Investigator

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital

Chelsea, Michigan, 48118

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Tareq Al baghdadi · Principal Investigator

Henry Ford Macomb Hospital-Clinton Township

Clinton Township, Michigan, 48038

Recruiting
Site Public Contact · Contact
313-916-3721CTOResearch@hfhs.org
Gazala Khan · Principal Investigator

Henry Ford Medical Center-Fairlane

Dearborn, Michigan, 48126

Recruiting
Site Public Contact · Contact
313-916-3721CTOResearch@hfhs.org
Gazala Khan · Principal Investigator

Henry Ford Hospital

Detroit, Michigan, 48202

Recruiting
Site Public Contact · Contact
313-916-3721CTOResearch@hfhs.org
Gazala Khan · Principal Investigator

OSF Saint Francis Hospital and Medical Group

Escanaba, Michigan, 49829

Recruiting
Site Public Contact · Contact
920-433-8889WI_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Cancer Hematology Centers - Flint

Flint, Michigan, 48503

Recruiting
Site Public Contact · Contact
810-762-8038wstrong@ghci.org
Tareq Al baghdadi · Principal Investigator

Genesee Hematology Oncology PC

Flint, Michigan, 48503

Suspended

Genesys Hurley Cancer Institute

Flint, Michigan, 48503

Recruiting
Site Public Contact · Contact
810-762-8038wstrong@ghci.org
Tareq Al baghdadi · Principal Investigator

Hurley Medical Center

Flint, Michigan, 48503

Recruiting
Site Public Contact · Contact
810-762-8038wstrong@ghci.org
Tareq Al baghdadi · Principal Investigator

Allegiance Health

Jackson, Michigan, 49201

Recruiting
Site Public Contact · Contact
313-916-3721CTOResearch@hfhs.org
Gazala Khan · Principal Investigator

University of Michigan Health - Sparrow Lansing

Lansing, Michigan, 48912

Recruiting
Site Public Contact · Contact
517-364-3712harsha.trivedi@umhsparrow.org
Tareq Al baghdadi · Principal Investigator

Trinity Health Saint Mary Mercy Livonia Hospital

Livonia, Michigan, 48154

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Tareq Al baghdadi · Principal Investigator

Henry Ford Health Providence Novi Hospital

Novi, Michigan, 48374

Recruiting
Site Public Contact · Contact
248-849-5332kfife3@hfhs.org
Gazala Khan · Principal Investigator

Henry Ford Medical Center-Columbus

Novi, Michigan, 48377

Recruiting
Site Public Contact · Contact
313-916-3721CTOResearch@hfhs.org
Gazala Khan · Principal Investigator

Trinity Health Saint Joseph Mercy Oakland Hospital

Pontiac, Michigan, 48341

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Tareq Al baghdadi · Principal Investigator

Henry Ford Health Providence Southfield Hospital

Southfield, Michigan, 48075

Recruiting
Site Public Contact · Contact
248-849-5332kfife3@hfhs.org
Gazala Khan · Principal Investigator

Henry Ford West Bloomfield Hospital

West Bloomfield, Michigan, 48322

Recruiting
Site Public Contact · Contact
313-916-3721CTOResearch@hfhs.org
Gazala Khan · Principal Investigator

Henry Ford Wyandotte Hospital

Wyandotte, Michigan, 48192

Recruiting
Site Public Contact · Contact
nhay@hfhs.org
Gazala Khan · Principal Investigator

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus

Ypsilanti, Michigan, 48197

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Tareq Al baghdadi · Principal Investigator

Sanford Joe Lueken Cancer Center

Bemidji, Minnesota, 56601

Recruiting
Site Public Contact · Contact
218-333-5000OncologyClinicalTrialsFargo@sanfordhealth.org
Daniel Almquist · Principal Investigator

Essentia Health Saint Joseph's Medical Center

Brainerd, Minnesota, 56401

Recruiting
Site Public Contact · Contact
218-786-3308CancerTrials@EssentiaHealth.org
Bret E. Friday · Principal Investigator

Mercy Hospital

Coon Rapids, Minnesota, 55433

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
David M. King · Principal Investigator

Essentia Health - Deer River Clinic

Deer River, Minnesota, 56636

Recruiting
Site Public Contact · Contact
218-786-3308CancerTrials@EssentiaHealth.org
Bret E. Friday · Principal Investigator

Essentia Health Cancer Center

Duluth, Minnesota, 55805

Recruiting
Site Public Contact · Contact
218-786-3308CancerTrials@EssentiaHealth.org
Bret E. Friday · Principal Investigator

Fairview Southdale Hospital

Edina, Minnesota, 55435

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
David M. King · Principal Investigator

Essentia Health Hibbing Clinic

Hibbing, Minnesota, 55746

Recruiting
Site Public Contact · Contact
218-786-3308
Bret E. Friday · Principal Investigator

Saint John's Hospital - Healtheast

Maplewood, Minnesota, 55109

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
David M. King · Principal Investigator

Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
David M. King · Principal Investigator

Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
David M. King · Principal Investigator

Regions Hospital

Saint Paul, Minnesota, 55101

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
David M. King · Principal Investigator

United Hospital

Saint Paul, Minnesota, 55102

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
David M. King · Principal Investigator

Essentia Health Sandstone

Sandstone, Minnesota, 55072

Recruiting
Site Public Contact · Contact
218-786-3308CancerTrials@EssentiaHealth.org
Bret E. Friday · Principal Investigator

Essentia Health Virginia Clinic

Virginia, Minnesota, 55792

Recruiting
Site Public Contact · Contact
218-786-3308CancerTrials@EssentiaHealth.org
Bret E. Friday · Principal Investigator

Minnesota Oncology Hematology PA-Woodbury

Woodbury, Minnesota, 55125

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
David M. King · Principal Investigator

Saint Francis Medical Center

Cape Girardeau, Missouri, 63703

Recruiting
Site Public Contact · Contact
573-334-2230sfmc@sfmc.net
Bryan A. Faller · Principal Investigator

Siteman Cancer Center at Saint Peters Hospital

City of Saint Peters, Missouri, 63376

Recruiting
Site Public Contact · Contact
800-600-3606info@siteman.wustl.edu
Patrick Grierson · Principal Investigator

Siteman Cancer Center at West County Hospital

Creve Coeur, Missouri, 63141

Recruiting
Site Public Contact · Contact
800-600-3606info@siteman.wustl.edu
Patrick Grierson · Principal Investigator

University Health Truman Medical Center

Kansas City, Missouri, 64108

Recruiting
Site Public Contact · Contact
816-404-4375
Gary C. Doolittle · Principal Investigator

Washington University School of Medicine

St Louis, Missouri, 63110

Recruiting
Site Public Contact · Contact
800-600-3606info@siteman.wustl.edu
Patrick Grierson · Principal Investigator

Siteman Cancer Center-South County

St Louis, Missouri, 63129

Recruiting
Site Public Contact · Contact
800-600-3606info@siteman.wustl.edu
Patrick Grierson · Principal Investigator

Siteman Cancer Center at Christian Hospital

St Louis, Missouri, 63136

Recruiting
Site Public Contact · Contact
800-600-3606info@siteman.wustl.edu
Patrick Grierson · Principal Investigator

Community Hospital of Anaconda

Anaconda, Montana, 59711

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Billings Clinic Cancer Center

Billings, Montana, 59101

Recruiting
Site Public Contact · Contact
800-996-2663research@billingsclinic.org
John M. Schallenkamp · Principal Investigator

Saint Vincent Frontier Cancer Center

Billings, Montana, 59102

Recruiting
Site Public Contact · Contact
800-648-6274
Patrick W. Cobb · Principal Investigator

Bozeman Health Deaconess Hospital

Bozeman, Montana, 59715

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Benefis Sletten Cancer Institute

Great Falls, Montana, 59405

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Logan Health Medical Center

Kalispell, Montana, 59901

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Community Medical Center

Missoula, Montana, 59804

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Nebraska Medicine-Bellevue

Bellevue, Nebraska, 68123

Recruiting
Site Public Contact · Contact
402-559-6941unmcrsa@unmc.edu
Laura L. Tenner · Principal Investigator

Nebraska Medicine-Village Pointe

Omaha, Nebraska, 68118

Recruiting
Site Public Contact · Contact
402-559-5600
Laura L. Tenner · Principal Investigator

University of Nebraska Medical Center

Omaha, Nebraska, 68198

Recruiting
Site Public Contact · Contact
402-559-6941unmcrsa@unmc.edu
Laura L. Tenner · Principal Investigator

OptumCare Cancer Care at Charleston

Las Vegas, Nevada, 89102

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

OptumCare Cancer Care at Fort Apache

Las Vegas, Nevada, 89183

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

Renown Regional Medical Center

Reno, Nevada, 89502

Recruiting
Site Public Contact · Contact
702-384-0013research@sncrf.org
John A. Ellerton · Principal Investigator

Jefferson Cherry Hill Hospital

Cherry Hill, New Jersey, 08002

Recruiting
Site Public Contact · Contact
215-600-9151ONCTrialNow@jefferson.edu
Daniel Lin · Principal Investigator

Englewood Hospital and Medical Center

Englewood, New Jersey, 07631

Active Not Recruiting

Sidney Kimmel Cancer Center Washington Township

Sewell, New Jersey, 08080

Recruiting
Site Public Contact · Contact
215-600-9151ONCTrialNow@jefferson.edu
Daniel Lin · Principal Investigator

Lovelace Medical Center-Saint Joseph Square

Albuquerque, New Mexico, 87102

Recruiting
Site Public Contact · Contact
505-272-0530ZPollock@salud.unm.edu
Jessica Belmonte · Principal Investigator

University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106

Recruiting
Site Public Contact · Contact
505-925-0348HSC-ClinicalTrialInfo@salud.unm.edu
Jessica Belmonte · Principal Investigator

Northwell Health Imbert Cancer Center

Bay Shore, New York, 11706

Recruiting
Site Public Contact · Contact
516-734-8896
Crystal Antoine-Pepeljugoski · Principal Investigator

Roswell Park Cancer Institute

Buffalo, New York, 14263

Recruiting
Site Public Contact · Contact
800-767-9355askroswell@roswellpark.org
Kannan Thanikachalam · Principal Investigator

Glens Falls Hospital

Glens Falls, New York, 12801

Recruiting
Site Public Contact · Contact
518-926-6700
Charles Yun · Principal Investigator

Northwell Health Cancer Institute at Huntington

Greenlawn, New York, 11740

Recruiting
Site Public Contact · Contact
516-734-8896
Crystal Antoine-Pepeljugoski · Principal Investigator

Northwell Health/Center for Advanced Medicine

Lake Success, New York, 11042

Recruiting
Site Public Contact · Contact
516-734-8896
Crystal Antoine-Pepeljugoski · Principal Investigator

NYU Langone Hospital - Long Island

Mineola, New York, 11501

Recruiting
Site Public Contact · Contact
212-263-4432cancertrials@nyulangone.org
Jennifer W. Chuy · Principal Investigator

Northern Westchester Hospital

Mount Kisco, New York, 10549

Recruiting
Site Public Contact · Contact
914-666-1366AMellor@northwell.edu
Crystal Antoine-Pepeljugoski · Principal Investigator

Laura and Isaac Perlmutter Cancer Center at NYU Langone

New York, New York, 10016

Recruiting
Site Public Contact · Contact
CancerTrials@nyulangone.org
Jennifer W. Chuy · Principal Investigator

University of Rochester

Rochester, New York, 14642

Recruiting
Site Public Contact · Contact
585-275-5830
Richard F. Dunne · Principal Investigator

Phelps Memorial Hospital Center

Sleepy Hollow, New York, 10591

Recruiting
Site Public Contact · Contact
914-366-1600
Crystal Antoine-Pepeljugoski · Principal Investigator

Cone Health Cancer Center at Asheboro

Asheboro, North Carolina, 27203

Suspended

Cone Health MedCenter Asheboro

Asheboro, North Carolina, 27205

Recruiting
Site Public Contact · Contact
336-832-0836stacey.phelps@conehealth.com
Vinay K. Gudena · Principal Investigator

Cone Health Cancer Center at Alamance Regional

Burlington, North Carolina, 27215

Recruiting
Site Public Contact · Contact
336-832-0836stacey.phelps@conehealth.com
Vinay K. Gudena · Principal Investigator

Southeastern Medical Oncology Center-Clinton

Clinton, North Carolina, 28328

Recruiting
Site Public Contact · Contact
919-587-9084jfields@cancersmoc.com
Samer S. Kasbari · Principal Investigator

Southeastern Medical Oncology Center-Goldsboro

Goldsboro, North Carolina, 27534

Recruiting
Site Public Contact · Contact
919-587-9084jfields@cancersmoc.com
Samer S. Kasbari · Principal Investigator

Cone Health Cancer Center

Greensboro, North Carolina, 27403

Recruiting
Site Public Contact · Contact
336-832-0836stacey.phelps@conehealth.com
Vinay K. Gudena · Principal Investigator

Cone Health Cancer Center at Drawbridge Parkway

Greensboro, North Carolina, 27410

Recruiting
Site Public Contact · Contact
336-832-0836stacey.phelps@conehealth.com
Vinay K. Gudena · Principal Investigator

Southeastern Medical Oncology Center-Jacksonville

Jacksonville, North Carolina, 28546

Recruiting
Site Public Contact · Contact
910-587-9084jfields@cancersmoc.com
Samer S. Kasbari · Principal Investigator

FirstHealth of the Carolinas-Moore Regional Hospital

Pinehurst, North Carolina, 28374

Recruiting
Site Public Contact · Contact
910-715-3500jcwilliams@firsthealth.org
Charles S. Kuzma · Principal Investigator

Annie Penn Memorial Hospital

Reidsville, North Carolina, 27320

Recruiting
Site Public Contact · Contact
336-832-0836stacey.phelps@conehealth.com
Vinay K. Gudena · Principal Investigator

Sanford Bismarck Medical Center

Bismarck, North Dakota, 58501

Recruiting
Site Public Contact · Contact
701-323-5760OncologyClinicalTrialsFargo@sanfordhealth.org
Daniel Almquist · Principal Investigator

Essentia Health Cancer Center-South University Clinic

Fargo, North Dakota, 58103

Recruiting
Site Public Contact · Contact
218-786-3308CancerTrials@EssentiaHealth.org
Bret E. Friday · Principal Investigator

Sanford Broadway Medical Center

Fargo, North Dakota, 58122

Recruiting
Site Public Contact · Contact
701-323-5760OncologyClinicalTrialsFargo@sanfordhealth.org
Daniel Almquist · Principal Investigator

Sanford Roger Maris Cancer Center

Fargo, North Dakota, 58122

Recruiting
Site Public Contact · Contact
701-234-6161OncologyClinicalTrialsFargo@sanfordhealth.org
Daniel Almquist · Principal Investigator

Miami Valley Hospital South

Centerville, Ohio, 45459

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Tarek M. Sabagh · Principal Investigator

Good Samaritan Hospital - Cincinnati

Cincinnati, Ohio, 45220

Recruiting
Site Public Contact · Contact
720-874-1881ResearchInstituteInquiries@CommonSpirit.org
Shahzad Siddique · Principal Investigator

Miami Valley Hospital

Dayton, Ohio, 45409

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Tarek M. Sabagh · Principal Investigator

Premier Blood and Cancer Center

Dayton, Ohio, 45409

Recruiting
Site Public Contact · Contact
937-276-8320
Tarek M. Sabagh · Principal Investigator

Miami Valley Hospital North

Dayton, Ohio, 45415

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Tarek M. Sabagh · Principal Investigator

Atrium Medical Center-Middletown Regional Hospital

Franklin, Ohio, 45005-1066

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Tarek M. Sabagh · Principal Investigator

Miami Valley Cancer Care and Infusion

Greenville, Ohio, 45331

Recruiting
Site Public Contact · Contact
937-569-7515
Tarek M. Sabagh · Principal Investigator

Upper Valley Medical Center

Troy, Ohio, 45373

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Tarek M. Sabagh · Principal Investigator

Cancer Centers of Southwest Oklahoma Research

Lawton, Oklahoma, 73505

Recruiting
Site Public Contact · Contact
877-231-4440
Hassan Hatoum · Principal Investigator

University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104

Recruiting
Site Public Contact · Contact
405-271-8777ou-clinical-trials@ouhsc.edu
Hassan Hatoum · Principal Investigator

Integris Southwest Medical Center

Oklahoma City, Oklahoma, 73109

Recruiting
Site Public Contact · Contact
888-823-5923ctsucontact@westat.com
Hassan Hatoum · Principal Investigator

Integris Cancer Institute of Oklahoma

Oklahoma City, Oklahoma, 73142

Recruiting
Site Public Contact · Contact
405-773-6613
Hassan Hatoum · Principal Investigator

Oklahoma Cancer Specialists and Research Institute-Tulsa

Tulsa, Oklahoma, 74146

Recruiting
Site Public Contact · Contact
918-505-3200
Mark B. Jennings · Principal Investigator

Providence Newberg Medical Center

Newberg, Oregon, 97132

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Charles W. Drescher · Principal Investigator

Saint Alphonsus Cancer Care Center-Ontario

Ontario, Oregon, 97914

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
Tareq Al baghdadi · Principal Investigator

Providence Willamette Falls Medical Center

Oregon City, Oregon, 97045

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Charles W. Drescher · Principal Investigator

Providence Portland Medical Center

Portland, Oregon, 97213

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Charles W. Drescher · Principal Investigator

Providence Saint Vincent Medical Center

Portland, Oregon, 97225

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Charles W. Drescher · Principal Investigator

Oregon Health and Science University

Portland, Oregon, 97239

Recruiting
Site Public Contact · Contact
503-494-1080trials@ohsu.edu
Emerson Y. Chen · Principal Investigator

Lehigh Valley Hospital-Cedar Crest

Allentown, Pennsylvania, 18103

Recruiting
Site Public Contact · Contact
610-402-9543Morgan_M.Horton@lvhn.org
Tareq Al baghdadi · Principal Investigator

UPMC-Heritage Valley Health System Beaver

Beaver, Pennsylvania, 15009

Recruiting
Site Public Contact · Contact
412-389-5208haneydl@upmc.edu
Anwaar Saeed · Principal Investigator

Lehigh Valley Hospital - Muhlenberg

Bethlehem, Pennsylvania, 18017

Recruiting
Site Public Contact · Contact
610-402-9543Morgan_M.Horton@lvhn.org
Tareq Al baghdadi · Principal Investigator

Geisinger Medical Center

Danville, Pennsylvania, 17822

Recruiting
Site Public Contact · Contact
570-271-5251HemonCCTrials@geisinger.edu
Mina Makary · Principal Investigator

Geisinger Cancer Center Dickson City

Dickson City, Pennsylvania, 18519

Recruiting
Site Public Contact · Contact
877-204-6081hemoncctrials@geisinger.edu
Mina Makary · Principal Investigator

Pocono Medical Center

East Stroudsburg, Pennsylvania, 18301

Recruiting
Site Public Contact · Contact
610-402-9543Morgan_M.Horton@lvhn.org
Tareq Al baghdadi · Principal Investigator

UPMC Hillman Cancer Center Erie

Erie, Pennsylvania, 16505

Recruiting
Site Public Contact · Contact
412-864-7716ClinicalResearchServices@upmc.edu
Anwaar Saeed · Principal Investigator

UPMC Cancer Centers - Arnold Palmer Pavilion

Greensburg, Pennsylvania, 15601

Recruiting
Site Public Contact · Contact
724-838-1900
Anwaar Saeed · Principal Investigator

UPMC Pinnacle Cancer Center/Community Osteopathic Campus

Harrisburg, Pennsylvania, 17109

Recruiting
Site Public Contact · Contact
717-724-6765klitchfield@PINNACLEHEALTH.org
Anwaar Saeed · Principal Investigator

Lehigh Valley Hospital-Hazleton

Hazleton, Pennsylvania, 18201

Recruiting
Site Public Contact · Contact
610-402-9543Morgan_M.Horton@lvhn.org
Tareq Al baghdadi · Principal Investigator

UPMC-Johnstown/John P. Murtha Regional Cancer Center

Johnstown, Pennsylvania, 15901

Recruiting
Site Public Contact · Contact
814-534-4724
Anwaar Saeed · Principal Investigator

Lancaster General Ann B Barshinger Cancer Institute

Lancaster, Pennsylvania, 17601

Recruiting
Site Public Contact · Contact
215-349-8245PMCancerResearch@pennmedicine.upenn.edu
Efrat Dotan · Principal Investigator

Geisinger Medical Oncology-Lewisburg

Lewisburg, Pennsylvania, 17837

Recruiting
Site Public Contact · Contact
570-374-8555HemonCCTrials@geisinger.edu
Mina Makary · Principal Investigator

UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion

Mechanicsburg, Pennsylvania, 17050

Recruiting
Site Public Contact · Contact
412-389-5208haneydl@upmc.edu
Anwaar Saeed · Principal Investigator

UPMC Hillman Cancer Center - Monroeville

Monroeville, Pennsylvania, 15146

Recruiting
Site Public Contact · Contact
412-864-7716ClinicalResearchServices@upmc.edu
Anwaar Saeed · Principal Investigator

Arnold Palmer Cancer Center Medical Oncology Norwin

N. Huntingdon, Pennsylvania, 15642

Recruiting
Site Public Contact · Contact
412-864-7716ClinicalResearchServices@upmc.edu
Anwaar Saeed · Principal Investigator

UPMC Hillman Cancer Center - New Castle

New Castle, Pennsylvania, 16105

Recruiting
Site Public Contact · Contact
412-389-5208haneydl@upmc.edu
Anwaar Saeed · Principal Investigator

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107

Recruiting
Site Public Contact · Contact
215-600-9151ONCTrialNow@jefferson.edu
Daniel Lin · Principal Investigator

Jefferson Torresdale Hospital

Philadelphia, Pennsylvania, 19114

Recruiting
Site Public Contact · Contact
215-600-9151ONCTrialNow@jefferson.edu
Daniel Lin · Principal Investigator

UPMC-Saint Margaret

Pittsburgh, Pennsylvania, 15215

Recruiting
Site Public Contact · Contact
412-784-4900
Anwaar Saeed · Principal Investigator

University of Pittsburgh Cancer Institute (UPCI)

Pittsburgh, Pennsylvania, 15232

Recruiting
Site Public Contact · Contact
412-647-8073
Anwaar Saeed · Principal Investigator

UPMC-Passavant Hospital

Pittsburgh, Pennsylvania, 15237

Recruiting
Site Public Contact · Contact
412-367-6454
Anwaar Saeed · Principal Investigator

UPMC-Saint Clair Hospital Cancer Center

Pittsburgh, Pennsylvania, 15243

Recruiting
Site Public Contact · Contact
412-502-3920
Anwaar Saeed · Principal Investigator

Community Medical Center

Scranton, Pennsylvania, 18510

Recruiting
Site Public Contact · Contact
570-703-4768HemonCCTrials@geisinger.edu
Mina Makary · Principal Investigator

UPMC Cancer Center at UPMC Northwest

Seneca, Pennsylvania, 16346

Recruiting
Site Public Contact · Contact
814-676-7900
Anwaar Saeed · Principal Investigator

UPMC Cancer Center-Uniontown

Uniontown, Pennsylvania, 15401

Recruiting
Site Public Contact · Contact
protocols@swog.org
Anwaar Saeed · Principal Investigator

Geisinger Wyoming Valley/Henry Cancer Center

Wilkes-Barre, Pennsylvania, 18711

Recruiting
Site Public Contact · Contact
570-271-5251HemonCCTrials@geisinger.edu
Mina Makary · Principal Investigator

Asplundh Cancer Pavilion

Willow Grove, Pennsylvania, 19090

Recruiting
Site Public Contact · Contact
215-600-9151ONCTrialNow@jefferson.edu
Daniel Lin · Principal Investigator

Smilow Cancer Hospital Care Center - Westerly

Westerly, Rhode Island, 02891

Recruiting
Site Public Contact · Contact
203-785-5702canceranswers@yale.edu
Yifei Zhang · Principal Investigator

Ralph H Johnson VA Medical Center

Charleston, South Carolina, 29401

Recruiting
Site Public Contact · Contact
843-789-7020ashley.salvo@va.gov
Oleksandra Lupak · Principal Investigator

Medical University of South Carolina

Charleston, South Carolina, 29425

Recruiting
Site Public Contact · Contact
843-792-9321hcc-clinical-trials@musc.edu
Toros Dincman · Principal Investigator

Rapid City Regional Hospital

Rapid City, South Dakota, 57701

Recruiting
Site Public Contact · Contact
605-755-2370research@monument.health
Abdel-Ghani Azzouqa · Principal Investigator

Sanford Cancer Center Oncology Clinic

Sioux Falls, South Dakota, 57104

Recruiting
Site Public Contact · Contact
605-312-3320OncologyClinicTrialsSF@sanfordhealth.org
Daniel Almquist · Principal Investigator

Sanford USD Medical Center - Sioux Falls

Sioux Falls, South Dakota, 57117-5134

Recruiting
Site Public Contact · Contact
605-312-3320OncologyClinicalTrialsSF@SanfordHealth.org
Daniel Almquist · Principal Investigator

Vanderbilt University/Ingram Cancer Center

Nashville, Tennessee, 37232

Recruiting
Site Public Contact · Contact
800-811-8480
Rajiv Agarwal · Principal Investigator

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center

Houston, Texas, 77030

Recruiting
Site Public Contact · Contact
713-798-1354burton@bcm.edu
Karen Riggins · Principal Investigator

Ben Taub General Hospital

Houston, Texas, 77030

Recruiting
Site Public Contact · Contact
713-873-2000
Karen Riggins · Principal Investigator

Farmington Health Center

Farmington, Utah, 84025

Recruiting
Site Public Contact · Contact
888-424-2100cancerinfo@hci.utah.edu
Christopher D. Nevala-Plagemann · Principal Investigator

University of Utah Sugarhouse Health Center

Salt Lake City, Utah, 84106

Recruiting
Site Public Contact · Contact
888-424-2100cancerinfo@hci.utah.edu
Christopher D. Nevala-Plagemann · Principal Investigator

Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112

Recruiting
Site Public Contact · Contact
888-424-2100cancerinfo@hci.utah.edu
Christopher D. Nevala-Plagemann · Principal Investigator

Central Vermont Medical Center/National Life Cancer Treatment

Berlin Corners, Vermont, 05602

Active Not Recruiting

University of Vermont Medical Center

Burlington, Vermont, 05401

Active Not Recruiting

University of Vermont and State Agricultural College

Burlington, Vermont, 05405

Active Not Recruiting

VCU Massey Cancer Center at Stony Point

Richmond, Virginia, 23235

Recruiting
Site Public Contact · Contact
ctoclinops@vcu.edu
Jennifer L. Myers · Principal Investigator

VCU Massey Comprehensive Cancer Center

Richmond, Virginia, 23298

Recruiting
Site Public Contact · Contact
804-628-6430CTOclinops@vcu.edu
Jennifer L. Myers · Principal Investigator

Langlade Hospital and Cancer Center

Antigo, Wisconsin, 54409

Recruiting
Site Public Contact · Contact
715-623-9869Juli.Alford@aspirus.org
Andrew J. Huang · Principal Investigator

Duluth Clinic Ashland

Ashland, Wisconsin, 54806

Recruiting
Site Public Contact · Contact
218-786-3308CancerTrials@EssentiaHealth.org
Bret E. Friday · Principal Investigator

Aurora Cancer Care-Southern Lakes VLCC

Burlington, Wisconsin, 53105

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

Aurora Saint Luke's South Shore

Cudahy, Wisconsin, 53110

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

Marshfield Medical Center-EC Cancer Center

Eau Claire, Wisconsin, 54701

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

Aurora Health Care Germantown Health Center

Germantown, Wisconsin, 53022

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

Aurora Cancer Care-Grafton

Grafton, Wisconsin, 53024

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

Saint Vincent Hospital Cancer Center Green Bay

Green Bay, Wisconsin, 54301

Recruiting
Site Public Contact · Contact
920-433-8889WI_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Saint Vincent Hospital Cancer Center at Saint Mary's

Green Bay, Wisconsin, 54303

Recruiting
Site Public Contact · Contact
920-433-8889wi_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Aurora BayCare Medical Center

Green Bay, Wisconsin, 54311

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

Aurora Cancer Care-Kenosha South

Kenosha, Wisconsin, 53142

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

William S Middleton VA Medical Center

Madison, Wisconsin, 53705

Recruiting
Site Public Contact · Contact
608-256-1901
Sam J. Lubner · Principal Investigator

University of Wisconsin Carbone Cancer Center - Eastpark Medical Center

Madison, Wisconsin, 53718

Recruiting
Site Public Contact · Contact
800-622-8922clinicaltrials@cancer.wisc.edu
Nataliya V. Uboha · Principal Investigator

University of Wisconsin Carbone Cancer Center - University Hospital

Madison, Wisconsin, 53792

Recruiting
Site Public Contact · Contact
800-622-8922clinicaltrials@cancer.wisc.edu
Nataliya V. Uboha · Principal Investigator

Aurora Bay Area Medical Group-Marinette

Marinette, Wisconsin, 54143

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

Marshfield Medical Center-Marshfield

Marshfield, Wisconsin, 54449

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

Aspirus Medford Hospital

Medford, Wisconsin, 54451

Recruiting
Site Public Contact · Contact
715-847-2353Beth.Knetter@aspirus.org
Andrew J. Huang · Principal Investigator

Aurora Cancer Care-Milwaukee

Milwaukee, Wisconsin, 53209

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

Aurora Saint Luke's Medical Center

Milwaukee, Wisconsin, 53215

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

Aurora Sinai Medical Center

Milwaukee, Wisconsin, 53233

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

Marshfield Medical Center - Minocqua

Minocqua, Wisconsin, 54548

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

ProHealth D N Greenwald Center

Mukwonago, Wisconsin, 53149

Recruiting
Site Public Contact · Contact
research.institute@phci.org
Timothy R. Wassenaar · Principal Investigator

ProHealth Oconomowoc Memorial Hospital

Oconomowoc, Wisconsin, 53066

Recruiting
Site Public Contact · Contact
262-928-7878
Timothy R. Wassenaar · Principal Investigator

Saint Vincent Hospital Cancer Center at Oconto Falls

Oconto Falls, Wisconsin, 54154

Recruiting
Site Public Contact · Contact
920-433-8889WI_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Vince Lombardi Cancer Clinic - Oshkosh

Oshkosh, Wisconsin, 54904

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

Aurora Cancer Care-Racine

Racine, Wisconsin, 53406

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

Aspirus Cancer Care - James Beck Cancer Center

Rhinelander, Wisconsin, 54501

Recruiting
Site Public Contact · Contact
715-847-2353Beth.Knetter@aspirus.org
Andrew J. Huang · Principal Investigator

Saint Vincent Hospital Cancer Center at Sheboygan

Sheboygan, Wisconsin, 53081

Recruiting
Site Public Contact · Contact
920-433-8889wi_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Sheboygan Physicians Group

Sheboygan, Wisconsin, 53081

Recruiting
Site Public Contact · Contact
920-433-8889wi_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Vince Lombardi Cancer Clinic-Sheboygan

Sheboygan, Wisconsin, 53081

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

Aspirus Cancer Care - Stevens Point

Stevens Point, Wisconsin, 54481

Recruiting
Site Public Contact · Contact
715-847-2353Beth.Knetter@aspirus.org
Andrew J. Huang · Principal Investigator

Marshfield Medical Center-River Region at Stevens Point

Stevens Point, Wisconsin, 54482

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

Saint Vincent Hospital Cancer Center at Sturgeon Bay

Sturgeon Bay, Wisconsin, 54235-1495

Recruiting
Site Public Contact · Contact
920-433-8889wi_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Aurora Medical Center in Summit

Summit, Wisconsin, 53066

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

Vince Lombardi Cancer Clinic-Two Rivers

Two Rivers, Wisconsin, 54241

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

ProHealth Waukesha Memorial Hospital

Waukesha, Wisconsin, 53188

Recruiting
Site Public Contact · Contact
262-928-7632
Timothy R. Wassenaar · Principal Investigator

UW Cancer Center at ProHealth Care

Waukesha, Wisconsin, 53188

Recruiting
Site Public Contact · Contact
262-928-5539Chanda.miller@phci.org
Timothy R. Wassenaar · Principal Investigator

Aspirus Regional Cancer Center

Wausau, Wisconsin, 54401

Recruiting
Site Public Contact · Contact
877-405-6866
Andrew J. Huang · Principal Investigator

Aurora Cancer Care-Milwaukee West

Wauwatosa, Wisconsin, 53226

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

Aurora West Allis Medical Center

West Allis, Wisconsin, 53227

Recruiting
Site Public Contact · Contact
414-302-2304ncorp@aurora.org
Edward S. James · Principal Investigator

Marshfield Medical Center - Weston

Weston, Wisconsin, 54476

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Seth O. Fagbemi · Principal Investigator

Aspirus Cancer Care - Wisconsin Rapids

Wisconsin Rapids, Wisconsin, 54494

Recruiting
Site Public Contact · Contact
715-422-7718
Andrew J. Huang · Principal Investigator

References

  • Saeed A, Colby S, Oberstein PE, Duda DG, Park R, Agarwal R, Figueroa-Moseley C, Vaidya R, Unger JM, Guthrie KA, Rocha FG, Senthil M, Safyan RA, Wainberg ZA, Iqbal S, Chiorean EG, Philip PA. S2303: phase II/III trial of paclitaxel + ramucirumab +/- nivolumab in gastric and esophageal adenocarcinoma (PARAMUNE). Future Oncol. 2025 May;21(11):1325-1331. doi: 10.1080/14796694.2025.2485020. Epub 2025 Mar 28.(PubMed)
Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial | Cancerify