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Improved Successful Retrieval Rate of HydroMARK Plus Breast Biopsy Site Marker in Comparison to HydroMARK as Well as Improved Surgeon Satisfaction

NCT ID: NCT06294574Sponsor: University of Alabama at BirminghamLast updated: 2025-09-22

Summary

The purpose of the study is to test how successful the retrieval rate of the new HydroMARK Plus Breast Biopsy Site Marker in comparison to HydroMARK.

Detailed description

Study objectives Primary objective Assess the successful retrieval rates of the HydroMARK Plus clip Secondary objective Determine the level of satisfaction of the surgeon with the retrieval of the HydroMARK Plus clip

Arms & interventions

  • DeviceHydroMARK Plus Clip

    Each patient will undergo a breast localization procedure, and a HydroMARK plus clip will be placed.

Outcome measures

Primary

  • Retrieval rate of the HydroMARK Plus clip.

    The primary endpoint of HydroMARK Plus retrieval rate will be estimated with % and two-sided 95% CI using normal approximation. A paired McNemar Test will be used to compare HydroMARK Plus retrieval rate and HydroMARK retrieval rate, and the 95% CI for the difference of retrieve rate will be estimated using the Newcombe's Score method.

    Time frame: Date of HydroMARK Plus Clip placement to 1 week plus or minus 5 days

Secondary

  • Level of satisfaction of the surgeon with the retrieval of the HydroMARK Plus clip.

    Time frame: Date of retrieval surgery to 1 week.

Eligibility criteria

Sex: FemaleAge: 18 Years to 90 YearsHealthy volunteers: No
Inclusion Criteria: * Patients with biopsy clips scheduled for surgery with SCOUT localization Exclusion Criteria: * Patients who didn't have surgery, patients younger than 18 years old * Patients older than 90 years old * Inmates * Non-English speakers

Study locations (1)

The Kirklin Clinic

Birmingham, Alabama, 35249

Recruiting
Quenteeria Mooney · Contact
Ceren Yalniz, MD · Principal Investigator
Improved Successful Retrieval Rate of HydroMARK Plus Breast Biopsy Site Marker in Comparison to HydroMARK as Well as Improved Surgeon Satisfaction | Cancerify