Cancerify Logo
Log inSign up
Back to clinical trials
RecruitingObservational

Sarcoma Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography

NCT ID: NCT06409013Sponsor: Mayo ClinicLast updated: 2026-02-06

Summary

This study evaluates the effectiveness of intraoperative indocyanine green dye and fluoroscopic technology in confirming negative margins after tumor removal.

Detailed description

PRIMARY OBJECTIVE: I. To evaluate the use of indocyanine green (ICG) as an intraoperative guide during bone and soft tissue sarcoma resection. OUTLINE: This is an observational study. Patients receive ICG infusion prior to undergoing scheduled resection and have medical records reviewed on study.

Arms & interventions

  • OtherNon-Interventional Study

    Non-interventional study

Outcome measures

Primary

  • Accuracy of intraoperative ICG fluorescence compared to final pathology results

    Intraoperative ICG fluorescence and deduced margins will be analyzed and compared the accuracy to final pathology margins. Negative predictive value will be calculated.

    Time frame: Baseline

Eligibility criteria

Sex: AllAge: 18 Years and olderHealthy volunteers: No
Inclusion Criteria: * Patients with biopsy-proven bone or soft tissue sarcoma undergoing resection Exclusion Criteria: * \* Age less than 18 * Chronic kidney disease * Anaphylaxis to dyes

Study locations (1)

Mayo Clinic in Rochester

Rochester, Minnesota, 55905

Recruiting
Clinical Trials Referral Office · Contact
Laura Dohrmann · Contact
Matthew T. Houdek, M.D. · Principal Investigator
Evaluation of Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography in Patients With Sarcoma | Cancerify