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RecruitingInterventional

Remote Exercise and Nutritional Prehabilitation for Pancreatic Cancer

NCT ID: NCT06423963Sponsor: H. Lee Moffitt Cancer Center and Research InstituteLast updated: 2026-05-06

Summary

The purpose of the study is to examine the feasibility and acceptability of an exercise and nutrition "prehabilitation" program for patients preparing for pancreatic cancer resection (removal).

Arms & interventions

  • BehavioralPhysical Activity

    Each participant will receive a Fitbit device with instruction and encouragement to self-monitor physical activity using step counts.

  • BehavioralNutrition Counseling

    Participants will receive nutritional counseling with a registered dietician.

  • BehavioralResistance Training

    Participants will engage in progressive, full-body resistance training based on American College of Sports Medicine (ACSM) guidelines.

Outcome measures

Primary

  • Feasibility and acceptability of PA/N and RT/N programs

    The number of participants who complete T1 and T0 measures.

    Time frame: Up to 16 weeks

Secondary

  • Examine exploratory outcomes and clinical characteristics

    Time frame: Up to 16 weeks

  • Compare clinical and treatment outcomes

    Time frame: Up to 16 weeks

Eligibility criteria

Sex: AllAge: 18 Years and olderHealthy volunteers: No
Inclusion Criteria: * Age 18 years or older * Biopsy-proven pancreatic ductal adenocarcinoma (PDAC), borderline resectable at diagnosis * Eastern Cooperative Oncology Group (ECOG) performance status 0-2 * Undergoing neoadjuvant chemotherapy with treatment plan including chemoradiation therapy and surgical resection * Ability to read and speak English Exclusion Criteria: * Regular engagement in RT (2x/week targeting all major muscle groups) * Screen failure for exercise safety based on PAR-Q * Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease * Recent fracture or acute musculoskeletal injury that precludes ability to participate in RT * Numeric pain rating scale greater than or equal to a 7 out of 10 * Myopathic or rheumatologic disease that impacts physical function

Study locations (1)

Moffitt Cancer Center

Tampa, Florida, 33612

Recruiting
Morgan Bean · Contact
813-745-1786morgan.bean@moffitt.org
Nathan Parker, PhD · Principal Investigator
Pamela Hodul, MD · Principal Investigator
Sylvia Crowder, PhD · Sub Investigator
Remote Exercise and Nutritional Prehabilitation for Pancreatic Cancer | Cancerify