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RecruitingInterventionalPhase 3

Randomized Phase III Trial INcorporating Pathologic Complete ReSponse in Participants With Early StaGe Non Small Cell Lung Cancer to Optimize ImmunotHerapy in The AdjuvanT Setting (INSIGHT)

NCT ID: NCT06498635Sponsor: National Cancer Institute (NCI)Last updated: 2026-06-18

Summary

This phase III trial compares durvalumab to the usual approach (patient observation) after surgery for the treatment of patients with early-stage non-small cell lung cancer. Immunotherapy with monoclonal antibodies, such as durvalumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. The usual approach for patients who are not in a study is to closely watch a patient's condition after surgery and to have regular visits with their doctor to watch for signs of the cancer coming back. Usually, patients do not receive further treatment unless the cancer returns. This study will help determine whether this different approach with durvalumab is better, the same, or worse than the usual approach of observation. Giving durvalumab may help patients live longer and prevent early-stage non-small cell lung cancer from coming back as compared to the usual approach.

Detailed description

PRIMARY OBJECTIVE: I. To compare disease free survival (DFS) in stage II-IIIB non-small cell lung cancer participants who achieved a pathologic complete response (pCR) following standard of care neoadjuvant chemo-immunotherapy and are randomized to adjuvant durvalumab (MEDI4736) versus surveillance. SECONDARY OBJECTIVES: I. To compare the overall survival (OS) between the arms. II. To evaluate the frequency and severity of toxicities of adjuvant durvalumab (MEDI4736). III. To compare the event free survival (EFS) between the arms. TRANSLATIONAL MEDICINE OBJECTIVE: I. To bank specimens and images for additional future translational medicine studies. QUALITY OF LIFE (QOL) PRIMARY OBJECTIVE: I. To compare patient-reported quality of life (QOL) status between treatment arms at 6 months from randomization using the Functional Assessment of Cancer Therapy-Lung (FACT-L) Trial Outcome Index (TOI). QOL SECONDARY OBJECTIVES: I. To compare patient-reported QOL between treatment arms at 24 weeks (6 months) from randomization using the Functional Assessment of Cancer Therapy-Biologic Response Modifier (FACT-BRM) physical and mental subscale scores. II. To compare longitudinal changes in global health status between treatment arms from randomization to 48 week (12 months) using the FACT-L TOI. PATIENT REPORTED OUTCOMES-COMMON TERMINOLOGY CRITERIA FOR ADVERSE EVENTS (PRO-CTCAE) OBJECTIVE: I. To compare participant-reported symptoms using selected PRO-CTCAE items between treatment arms such as rash, itching, skin dryness, numbness, and tingling. OUTLINE: Patients are randomized to 1 of 2 arms. ARM I: Patients receive durvalumab intravenously (IV) over 60 minutes on day 1 of each cycle. Treatment repeats every 28 days for up to 12 cycles in the absence of disease progression or unacceptable toxicity. Patients undergo computed tomography (CT) and blood sample collection throughout the trial. ARM II: Patients undergo active surveillance for 12 months on study. Patients undergo CT and blood sample collection throughout the trial. After completion of study treatment, patients are followed up annually until 10 years from randomization.

Arms & interventions

  • ProcedureBiospecimen Collection

    Undergo blood sample collection

  • ProcedureComputed Tomography

    Undergo CT

  • BiologicalDurvalumab

    Given IV

  • OtherPatient Observation

    Undergo active surveillance

  • OtherQuestionnaire Administration

    Ancillary studies

Outcome measures

Primary

  • Disease-free survival (DFS)

    Will be assessed using a 1-sided 5% level log-rank test accounting for interim testing, stratified on the randomization stratification factors.

    Time frame: From date of randomization to the earliest event defined as date of first documentation of recurrence, any new lung cancer (even in the contralateral lung), or death due to any cause, assessed up to 10 years

Secondary

  • Event-free survival (EFS)

    Time frame: From date of randomization to date of first occurrence of EFS event, assessed up to 10 years

  • Overall survival (OS)

    Time frame: From date of randomization to date of death due to any cause, assessed up to 10 years

  • Incidence of adverse events

    Time frame: Up to 10 years

Eligibility criteria

Sex: AllAge: 18 Years and olderHealthy volunteers: No
Inclusion Criteria: * Participants must have histologically or cytological confirmed diagnosis of clinical stage II-IIIB (excluding clinical N3 disease) non-small cell lung cancer (NSCLC) * Participants must have had a complete (R0) resection of NSCLC (with appropriate lymph node sampling as defined by the National Comprehensive Cancer Network \[NCCN\] guidelines) within 84 days (12 weeks) prior to randomization. Acceptable types of surgical resection are: lobectomy, sleeve resection, bi-lobectomy, or pneumonectomy. Wedge resection is not allowed. * Note the NCCN guidelines: N1 and N2 node resection and mapping is a routine component of lung cancer resections. It is recommended at a minimum one N1 and three N2 stations is sampled or complete lymph node dissection. Formal ipsilateral mediastinal lymph node dissection is indicated for participants undergoing resection for N2 disease * Participants must have a pathologic complete response (pCR) (no viable tumor in the resected specimen or lymph nodes), as determined by local pathology review * Participants must have a PD-L1 status result (e.g. \[\< 1% versus \>= 1% or unknown\]) * Participants must not have known EGFR mutations, or ALK gene fusion * Participants must have received at least two cycles of neoadjuvant platinum-based chemotherapy and anti-PD-1 or anti-PD-L1 therapy. The neoadjuvant treatment must be Food and Drug Administration (FDA) approved and standard of care as listed in NCCN guidelines * Participants must not be planning to receive any concurrent non-protocol directed chemotherapy, immunotherapy, biologic or hormonal therapy for NSCLC treatment while receiving treatment on this study * Participants must not have received any prior systemic therapy (systemic chemotherapy, immunotherapy or investigational drug) within 28 days prior to randomization * Participants must not have medical contraindications or severe adverse events to receiving anti-PD-1 or anti-PD-L1 therapy * Participants must not have received post-operative radiation therapy (PORT) for NSCLC * Participants must not have any unresolved toxicity National Cancer Institute (NCI) CTCAE grade ≥ 2 from previous anticancer therapy with the exception of alopecia, and vitiligo. Note, participants with grade ≥2 neuropathy may be included at the discretion of the treating investigator. Note, participants with irreversible toxicity not reasonably expected to be exacerbated by treatment with durvalumab may be included at the discretion of the treating investigator * Participant must be ≥ 18 years old at time of study entry * Participants must have body weight \> 30 kg * Participant must have Zubrod performance status of 0-2 * Participant must have a complete medical history and physical exam within 28 days prior to randomization * Hemoglobin \> 9.0 g/dL (within 28 days prior to randomization) * Absolute neutrophil count ≥ 1.5 x 10\^3/uL (within 28 days prior to randomization) * Platelets ≥ 100 x 10\^3/uL (within 28 days prior to randomization) * Total bilirubin ≤ 1 x institutional upper limit of normal (ULN) unless history of Gilbert's disease. Participants with history of Gilbert's disease must have total bilirubin ≤ 5 x institutional ULN (within 28 days prior to randomization) * Aspartate transaminase (AST)/alanine transaminase (ALT) ≤ 3 × institutional ULN (within 28 days prior to randomization) * Participants must have a calculated creatinine clearance ≥ 40 mL/min using the following Cockcroft-Gault formula. This specimen must have been drawn and processed within 28 days prior to randomization. For creatinine clearance formula see the tools on the Clinical Research Associate (CRA) Workbench https://txwb.crab.org/TXWB/Tools.aspx * Participants must have fully recovered from the effects of prior surgery in the opinion of the treating investigator * Participants with a known history of human immunodeficiency virus (HIV)-infection must be on effective anti-retroviral therapy at registration and have undetectable viral load test on the most recent test results obtained within 6 months prior to randomization * Participants with a known history of chronic hepatitis B virus (HBV) infection must have undetectable HBV viral load while on suppressive therapy on the most recent test results obtained within 6 months prior to randomization, if indicated * Participants with a known history of hepatitis C virus (HCV) infection must have been treated and cured. Participants currently being treated for HCV infection must have undetectable HCV viral load test on the most recent test results obtained within 6 months prior to randomization, if indicated * Participants must not have had an organ transplant * Participants must not have a prior or concurrent malignancy whose natural history or treatment (in the opinion of the treating physician) has the potential to interfere with the safety or efficacy assessment of the investigational regimen * Participant must not have medical contraindications to receiving immunotherapy, including history of non-infectious pneumonitis that required steroids or active autoimmune disease that has required systemic treatment with disease modifying agents, corticosteroids or immunosuppressive drugs in the past two years. Replacement therapy (e.g. thyroxine for pre-existing hypothyroidism, insulin for type I diabetes mellitus, or physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency, etc.) is not considered a form of systemic treatment. Intra-articular steroid injections are allowed * Participants must not be pregnant or nursing (nursing includes breast milk fed to an infant by any means, including from the breast, milk expressed by hand, or pumped). Individuals who are of reproductive potential must have agreed to use an effective contraceptive method during protocol therapy and for 6 months following completion of protocol therapy with details provided as a part of the consent process. A person who has had menses at any time in the preceding 12 consecutive months or who has semen likely to contain sperm is considered to be of "reproductive potential." In addition to routine contraceptive methods, "effective contraception" also includes refraining from sexual activity that might result in pregnancy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) including hysterectomy, bilateral oophorectomy, bilateral tubal ligation/occlusion, and vasectomy with testing showing no sperm in the semen. Participants should not breastfeed during protocol therapy and for 6 months following completion of protocol therapy * Participants must not have received a live or live attenuated vaccine within 28 days prior randomization. Examples of live vaccines include, but are not limited to, the following: measles, mumps, rubella, varicella/zoster, yellow fever rabies, Bacillus Calmette-Guerin (BCG) and typhoid vaccine. Seasonal influenza vaccines and coronavirus disease 19 (COVID-19) vaccines are allowed, however, intranasal influenza vaccines (e.g. Flu-Mist) are live attenuated, and are not allowed * Participants must be offered the opportunity to participate in specimen banking * Participants who can complete FACT-L, FACT-BRM, and PRO-CTCAE questionnaires forms in English, or Spanish must agree to participate in the patient-reported outcome study * NOTE: As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system * Participants must be informed of the investigational nature of this study and must sign and give informed consent in accordance with institutional and federal guidelines * For participants with impaired decision-making capabilities, legally authorized representatives may sign and give informed consent on behalf of study participants in accordance with applicable federal, local, and Central Institutional Review Board (CIRB) regulations

Study locations (245)

NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro

Jonesboro, Arkansas, 72401

Recruiting
Site Public Contact · Contact
870-936-7066Emily.Carvell@bmhcc.org
Osarenren Ogbeide · Principal Investigator

Tower Cancer Research Foundation

Beverly Hills, California, 90211

Recruiting
Site Public Contact · Contact
towercancerresearch@toweroncology.com
Karen L. Reckamp · Principal Investigator

Veterans Affairs Loma Linda Healthcare System

Loma Linda, California, 92357

Recruiting
Site Public Contact · Contact
800-741-8387
Steven B. Hardin · Principal Investigator

Cedars-Sinai Medical Center

Los Angeles, California, 90048

Recruiting
Site Public Contact · Contact
310-423-2133Cancer.trial.info@cshs.org
Karen L. Reckamp · Principal Investigator

University of California Davis Comprehensive Cancer Center

Sacramento, California, 95817

Recruiting
Site Public Contact · Contact
916-734-3089
Surbhi Singhal · Principal Investigator

Torrance Memorial Physician Network - Cancer Care

Torrance, California, 90505

Recruiting
Site Public Contact · Contact
310-750-3300courtney.steeneken@tmphysicians.com
Karen L. Reckamp · Principal Investigator

Saint Mary's Hospital and Regional Medical Center

Grand Junction, Colorado, 81501

Recruiting
Site Public Contact · Contact
303-777-2663ccrp@co-cancerresearch.org
Patrick W. Cobb · Principal Investigator

Hartford HealthCare - Avon

Avon, Connecticut, 06001

Recruiting
Site Public Contact · Contact
860-972-4700
Krishna S. Gunturu · Principal Investigator

Hartford Hospital

Hartford, Connecticut, 06102

Recruiting
Site Public Contact · Contact
860-545-5363
Krishna S. Gunturu · Principal Investigator

Hartford HealthCare - Manchester

Manchester, Connecticut, 06042

Recruiting
Site Public Contact · Contact
860-972-4700
Krishna S. Gunturu · Principal Investigator

Midstate Medical Center

Meriden, Connecticut, 06451

Recruiting
Site Public Contact · Contact
866-662-5678
Krishna S. Gunturu · Principal Investigator

The Hospital of Central Connecticut

New Britain, Connecticut, 06050

Recruiting
Site Public Contact · Contact
860-224-5660
Krishna S. Gunturu · Principal Investigator

Beebe South Coastal Health Campus

Millville, Delaware, 19967

Recruiting
Site Public Contact · Contact
302-291-6730research@beebehealthcare.org
Gregory A. Masters · Principal Investigator

Helen F Graham Cancer Center

Newark, Delaware, 19713

Recruiting
Site Public Contact · Contact
302-623-4450lbarone@christianacare.org
Gregory A. Masters · Principal Investigator

Medical Oncology Hematology Consultants PA

Newark, Delaware, 19713

Recruiting
Site Public Contact · Contact
302-623-4450lbarone@christianacare.org
Gregory A. Masters · Principal Investigator

Beebe Health Campus

Rehoboth Beach, Delaware, 19971

Recruiting
Site Public Contact · Contact
302-291-6730research@beebehealthcare.org
Gregory A. Masters · Principal Investigator

Moffitt Cancer Center-International Plaza

Tampa, Florida, 33607

Suspended

Moffitt Cancer Center - McKinley Campus

Tampa, Florida, 33612

Suspended

Moffitt Cancer Center

Tampa, Florida, 33612

Suspended

Emory University Hospital Midtown

Atlanta, Georgia, 30308

Recruiting
Site Public Contact · Contact
888-946-7447
Onkar V. Khullar · Principal Investigator

Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia, 30322

Recruiting
Site Public Contact · Contact
404-778-1868
Onkar V. Khullar · Principal Investigator

Emory Saint Joseph's Hospital

Atlanta, Georgia, 30342

Recruiting
Site Public Contact · Contact
404-851-7115
Onkar V. Khullar · Principal Investigator

Emory Decatur Hospital

Decatur, Georgia, 30033

Recruiting
Site Public Contact · Contact
440-778-1868clinicaltrialsoncology@dekalbmedical.org
Onkar V. Khullar · Principal Investigator

Emory Johns Creek Hospital

Johns Creek, Georgia, 30097

Recruiting
Site Public Contact · Contact
404-778-5714m.lisa.hwang@emory.edu
Onkar V. Khullar · Principal Investigator

Hawaii Cancer Care Inc - Waterfront Plaza

Honolulu, Hawaii, 96813

Recruiting
Site Public Contact · Contact
808-524-6115i.webster@hawaiicancercare.com
Nicolas Villanueva · Principal Investigator

Queen's Cancer Cenrer - POB I

Honolulu, Hawaii, 96813

Recruiting
Site Public Contact · Contact
808-532-0315
Nicolas Villanueva · Principal Investigator

Queen's Medical Center

Honolulu, Hawaii, 96813

Recruiting
Site Public Contact · Contact
808-545-8548
Nicolas Villanueva · Principal Investigator

Queen's Cancer Center - Kuakini

Honolulu, Hawaii, 96817

Recruiting
Site Public Contact · Contact
808-531-8521
Nicolas Villanueva · Principal Investigator

Hawaii Cancer Care - Westridge

‘Aiea, Hawaii, 96701

Recruiting
Site Public Contact · Contact
808-539-2273info@hawaiicancercare.com
Nicolas Villanueva · Principal Investigator

The Queen's Medical Center - West Oahu

‘Ewa Beach, Hawaii, 96706

Recruiting
Site Public Contact · Contact
rohta@queens.org
Nicolas Villanueva · Principal Investigator

Saint Luke's Cancer Institute - Boise

Boise, Idaho, 83712

Recruiting
Site Public Contact · Contact
208-381-2774eslinget@slhs.org
Charles W. Drescher · Principal Investigator

Kootenai Health - Coeur d'Alene

Coeur d'Alene, Idaho, 83814

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Saint Luke's Cancer Institute - Fruitland

Fruitland, Idaho, 83619

Recruiting
Site Public Contact · Contact
208-381-2774eslinget@slhs.org
Charles W. Drescher · Principal Investigator

Saint Luke's Cancer Institute - Meridian

Meridian, Idaho, 83642

Recruiting
Site Public Contact · Contact
208-381-2774eslinget@slhs.org
Charles W. Drescher · Principal Investigator

Saint Alphonsus Cancer Care Center-Nampa

Nampa, Idaho, 83687

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
Elie G. Dib · Principal Investigator

Saint Luke's Cancer Institute - Nampa

Nampa, Idaho, 83687

Recruiting
Site Public Contact · Contact
208-381-2774eslinget@slhs.org
Charles W. Drescher · Principal Investigator

Kootenai Clinic Cancer Services - Post Falls

Post Falls, Idaho, 83854

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Kootenai Clinic Cancer Services - Sandpoint

Sandpoint, Idaho, 83864

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Northwestern University

Chicago, Illinois, 60611

Recruiting
Site Public Contact · Contact
312-695-1301cancer@northwestern.edu
Young Kwang Chae · Principal Investigator

Northwestern Medicine Cancer Center Kishwaukee

DeKalb, Illinois, 60115

Recruiting
Site Public Contact · Contact
630-352-5360Donald.Smith3@nm.org
Young Kwang Chae · Principal Investigator

Northwestern Medicine Cancer Center Delnor

Geneva, Illinois, 60134

Recruiting
Site Public Contact · Contact
630-352-5360Donald.Smith3@nm.org
Young Kwang Chae · Principal Investigator

Northwestern Medicine Glenview Outpatient Center

Glenview, Illinois, 60026

Recruiting
Site Public Contact · Contact
312-695-1102
Young Kwang Chae · Principal Investigator

Northwestern Medicine Grayslake Outpatient Center

Grayslake, Illinois, 60030

Recruiting
Site Public Contact · Contact
312-695-1102
Young Kwang Chae · Principal Investigator

Northwestern Medicine Huntley Hospital

Huntley, Illinois, 60142

Recruiting
Site Public Contact · Contact
815-334-5566
Young Kwang Chae · Principal Investigator

Northwestern Medicine Lake Forest Hospital

Lake Forest, Illinois, 60045

Recruiting
Site Public Contact · Contact
cancertrials@northwestern.edu
Young Kwang Chae · Principal Investigator

Loyola University Medical Center

Maywood, Illinois, 60153

Recruiting
Site Public Contact · Contact
708-226-4357
Nan Sethakorn · Principal Investigator

Northwestern Medicine Oak Brook

Oak Brook, Illinois, 60523

Recruiting
Site Public Contact · Contact
nctnprogram_rhlccc@northwestern.edu
Young Kwang Chae · Principal Investigator

Northwestern Medicine Orland Park

Orland Park, Illinois, 60462

Recruiting
Site Public Contact · Contact
nctnprogram_rhlccc@northwestern.edu
Young Kwang Chae · Principal Investigator

Northwestern Medicine Cancer Center Warrenville

Warrenville, Illinois, 60555

Recruiting
Site Public Contact · Contact
630-352-5360Donald.Smith3@nm.org
Young Kwang Chae · Principal Investigator

IU Health West Hospital

Avon, Indiana, 46123

Recruiting
Site Public Contact · Contact
317-278-5632iutrials@iu.edu
Rohan Maniar · Principal Investigator

IU Health North Hospital

Carmel, Indiana, 46032

Recruiting
Site Public Contact · Contact
317-278-5632iutrials@iu.edu
Rohan Maniar · Principal Investigator

Indiana University/Melvin and Bren Simon Cancer Center

Indianapolis, Indiana, 46202

Recruiting
Site Public Contact · Contact
317-278-5632iutrials@iu.edu
Rohan Maniar · Principal Investigator

Sidney and Lois Eskenazi Hospital

Indianapolis, Indiana, 46202

Recruiting
Site Public Contact · Contact
317-278-5632iutrials@iu.edu
Rohan Maniar · Principal Investigator

Mary Greeley Medical Center

Ames, Iowa, 50010

Recruiting
Site Public Contact · Contact
515-956-4132
Joseph J. Merchant · Principal Investigator

McFarland Clinic - Ames

Ames, Iowa, 50010

Recruiting
Site Public Contact · Contact
515-239-4734ksoder@mcfarlandclinic.com
Joseph J. Merchant · Principal Investigator

UI Health Care Mission Cancer and Blood - Ankeny Clinic

Ankeny, Iowa, 50023

Recruiting
Site Public Contact · Contact
515-241-3305
Seema Harichand-Herdt · Principal Investigator

McFarland Clinic - Boone

Boone, Iowa, 50036

Suspended

Saint Anthony Regional Hospital

Carroll, Iowa, 51401

Recruiting
Site Public Contact · Contact
515-689-7658sbenson@iora.org
Seema Harichand-Herdt · Principal Investigator

UI Health Care Mission Cancer and Blood - West Des Moines Clinic

Clive, Iowa, 50325

Recruiting
Site Public Contact · Contact
515-241-3305
Seema Harichand-Herdt · Principal Investigator

Iowa Methodist Medical Center

Des Moines, Iowa, 50309

Recruiting
Site Public Contact · Contact
515-241-6727
Seema Harichand-Herdt · Principal Investigator

UI Health Care Mission Cancer and Blood - Des Moines Clinic

Des Moines, Iowa, 50309

Recruiting
Site Public Contact · Contact
515-241-3305
Seema Harichand-Herdt · Principal Investigator

Broadlawns Medical Center

Des Moines, Iowa, 50314

Recruiting
Site Public Contact · Contact
515-282-2200
Seema Harichand-Herdt · Principal Investigator

Mercy Medical Center - Des Moines

Des Moines, Iowa, 50314

Recruiting
Site Public Contact · Contact
515-241-3305
Richard L. Deming · Principal Investigator

UI Health Care Mission Cancer and Blood - Laurel Clinic

Des Moines, Iowa, 50314

Recruiting
Site Public Contact · Contact
515-241-3305
Seema Harichand-Herdt · Principal Investigator

McFarland Clinic - Trinity Cancer Center

Fort Dodge, Iowa, 50501

Recruiting
Site Public Contact · Contact
515-956-4132
Joseph J. Merchant · Principal Investigator

UI Healthcare Mission Cancer and Blood - Fort Dodge

Fort Dodge, Iowa, 50501

Recruiting
Site Public Contact · Contact
515-282-2921trials@missioncancer.com
Seema Harichand-Herdt · Principal Investigator

McFarland Clinic - Jefferson

Jefferson, Iowa, 50129

Suspended

McFarland Clinic - Marshalltown

Marshalltown, Iowa, 50158

Recruiting
Site Public Contact · Contact
515-956-4132
Joseph J. Merchant · Principal Investigator

UI Health Care Mission Cancer and Blood - Waukee Clinic

Waukee, Iowa, 50263

Recruiting
Site Public Contact · Contact
515-241-3305
Seema Harichand-Herdt · Principal Investigator

HaysMed

Hays, Kansas, 67601

Recruiting
Site Public Contact · Contact
785-623-5774
Gary C. Doolittle · Principal Investigator

Lawrence Memorial Hospital

Lawrence, Kansas, 66044

Recruiting
Site Public Contact · Contact
785-505-2800Stephanie.Norris@LMH.ORG
Gary C. Doolittle · Principal Investigator

The University of Kansas Cancer Center - Olathe

Olathe, Kansas, 66061

Recruiting
Site Public Contact · Contact
913-588-1569OlatheCCResearch@kumc.edu
Gary C. Doolittle · Principal Investigator

Salina Regional Health Center

Salina, Kansas, 67401

Recruiting
Site Public Contact · Contact
785-452-7038mleepers@srhc.com
Gary C. Doolittle · Principal Investigator

University of Kansas Health System Saint Francis Campus

Topeka, Kansas, 66606

Recruiting
Site Public Contact · Contact
785-295-8000
Gary C. Doolittle · Principal Investigator

University Medical Center New Orleans

New Orleans, Louisiana, 70112

Recruiting
Site Public Contact · Contact
504-210-3539emede1@lsuhsc.edu
Brian C. Boulmay · Principal Investigator

Harold Alfond Center for Cancer Care

Augusta, Maine, 04330

Recruiting
Site Public Contact · Contact
207-626-4855
Xiao Hu · Principal Investigator

MaineHealth Maine Medical Center- Scarborough

Scarborough, Maine, 04074

Recruiting
Site Public Contact · Contact
207-396-8670clinicalresearch@mainehealth.org
Xiao Hu · Principal Investigator

MaineHealth Cancer Care and IV Therapy - South Portland

South Portland, Maine, 04106

Recruiting
Site Public Contact · Contact
207-396-8670clinicalresearch@mainehealth.org
Xiao Hu · Principal Investigator

UM Upper Chesapeake Hematology and Oncology - Aberdeen

Aberdeen, Maryland, 21001

Recruiting
Site Public Contact · Contact
443-643-1029nfadrwoski@umm.edu
Ashkan Bahrani · Principal Investigator

UPMC Western Maryland

Cumberland, Maryland, 21502

Recruiting
Site Public Contact · Contact
240-964-1400
Liza C. Villaruz · Principal Investigator

Beverly Hospital

Beverly, Massachusetts, 01915

Recruiting
Site Public Contact · Contact
978-922-3000
Paul J. Hesketh · Principal Investigator

Lahey Hospital and Medical Center

Burlington, Massachusetts, 01805

Recruiting
Site Public Contact · Contact
781-744-3421lhmc-cancer-clinical-trials@lahey.org
Paul J. Hesketh · Principal Investigator

Addison Gilbert Hospital

Gloucester, Massachusetts, 01930

Recruiting
Site Public Contact · Contact
978-283-4000
Paul J. Hesketh · Principal Investigator

Lahey Clinic Peabody

Peabody, Massachusetts, 01960

Recruiting
Site Public Contact · Contact
781-744-3421lhmc-cancer-clinical-trials@lahey.org
Paul J. Hesketh · Principal Investigator

Baystate Medical Center

Springfield, Massachusetts, 01199

Recruiting
Site Public Contact · Contact
413-794-3565tamara.wrenn@baystatehealth.org
John C. McCann · Principal Investigator

UMass Memorial Medical Center - University Campus

Worcester, Massachusetts, 01655

Recruiting
Site Public Contact · Contact
508-856-3216cancer.research@umassmed.edu
William V. Walsh · Principal Investigator

University of Michigan Rogel Cancer Center

Ann Arbor, Michigan, 48109

Recruiting
Site Public Contact · Contact
800-865-1125CancerAnswerLine@med.umich.edu
Angel Qin · Principal Investigator

Bronson Battle Creek

Battle Creek, Michigan, 49017

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Trinity Health IHA Medical Group Hematology Oncology - Brighton

Brighton, Michigan, 48114

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Elie G. Dib · Principal Investigator

University of Michigan - Brighton Center for Specialty Care

Brighton, Michigan, 48116

Recruiting
Site Public Contact · Contact
800-865-1125
Angel Qin · Principal Investigator

Trinity Health IHA Medical Group Hematology Oncology - Canton

Canton, Michigan, 48188

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Elie G. Dib · Principal Investigator

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital

Chelsea, Michigan, 48118

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Elie G. Dib · Principal Investigator

Henry Ford Hospital

Detroit, Michigan, 48202

Recruiting
Site Public Contact · Contact
313-916-3721CTOResearch@hfhs.org
Adam M. Forman · Principal Investigator

Henry Ford Health Saint John Hospital

Detroit, Michigan, 48236

Recruiting
Site Public Contact · Contact
313-343-3166Kkeenan1@hfhs.org
Elie G. Dib · Principal Investigator

Henry Ford River District Hospital

East China Township, Michigan, 48054

Recruiting
Site Public Contact · Contact
313-343-3166kforman1@hfhs.org
Elie G. Dib · Principal Investigator

OSF Saint Francis Hospital and Medical Group

Escanaba, Michigan, 49829

Recruiting
Site Public Contact · Contact
920-433-8889WI_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Cancer Hematology Centers - Flint

Flint, Michigan, 48503

Recruiting
Site Public Contact · Contact
810-762-8038wstrong@ghci.org
Elie G. Dib · Principal Investigator

Genesee Hematology Oncology PC

Flint, Michigan, 48503

Suspended

Genesys Hurley Cancer Institute

Flint, Michigan, 48503

Recruiting
Site Public Contact · Contact
810-762-8038wstrong@ghci.org
Elie G. Dib · Principal Investigator

Corewell Health Grand Rapids Hospitals - Butterworth Hospital

Grand Rapids, Michigan, 49503

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Trinity Health Grand Rapids Hospital

Grand Rapids, Michigan, 49503

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Henry Ford Saint John Hospital - Academic

Grosse Pointe Woods, Michigan, 48236

Recruiting
Site Public Contact · Contact
313-343-3166kforman1@hfhs.org
Elie G. Dib · Principal Investigator

Henry Ford Saint John Hospital - Breast

Grosse Pointe Woods, Michigan, 48236

Recruiting
Site Public Contact · Contact
313-343-3166karen.forman@ascension.org
Elie G. Dib · Principal Investigator

Henry Ford Saint John Hospital - Van Elslander

Grosse Pointe Woods, Michigan, 48236

Recruiting
Site Public Contact · Contact
313-343-3166kforman1@hfhs.org
Elie G. Dib · Principal Investigator

Bronson Methodist Hospital

Kalamazoo, Michigan, 49007

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

West Michigan Cancer Center

Kalamazoo, Michigan, 49007

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

University of Michigan Health - Sparrow Lansing

Lansing, Michigan, 48912

Recruiting
Site Public Contact · Contact
517-364-3712harsha.trivedi@umhsparrow.org
Elie G. Dib · Principal Investigator

Trinity Health Saint Mary Mercy Livonia Hospital

Livonia, Michigan, 48154

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Elie G. Dib · Principal Investigator

Henry Ford Saint John Hospital - Macomb Medical

Macomb, Michigan, 48044

Recruiting
Site Public Contact · Contact
313-343-3166kforman1@hfhs.org
Elie G. Dib · Principal Investigator

Henry Ford Warren Hospital - Breast Macomb

Macomb, Michigan, 48044

Recruiting
Site Public Contact · Contact
313-343-3166kforman1@hfhs.org
Elie G. Dib · Principal Investigator

Trinity Health Muskegon Hospital

Muskegon, Michigan, 49444

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Corewell Health Lakeland Hospitals - Niles Hospital

Niles, Michigan, 49120

Recruiting
Site Public Contact · Contact
616-391-1230
Kathleen Y. Butler · Principal Investigator

Cancer and Hematology Centers of Western Michigan - Norton Shores

Norton Shores, Michigan, 49444

Recruiting
Site Public Contact · Contact
616-391-1230connie.szczepanek@crcwm.org
Kathleen Y. Butler · Principal Investigator

Henry Ford Health Providence Novi Hospital

Novi, Michigan, 48374

Recruiting
Site Public Contact · Contact
248-849-5332kfife3@hfhs.org
Adam M. Forman · Principal Investigator

Trinity Health Saint Joseph Mercy Oakland Hospital

Pontiac, Michigan, 48341

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Elie G. Dib · Principal Investigator

Corewell Health Reed City Hospital

Reed City, Michigan, 49677

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Corewell Health William Beaumont University Hospital

Royal Oak, Michigan, 48073

Recruiting
Site Public Contact · Contact
248-551-7695
Andrew A. Muskovitz · Principal Investigator

Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center

Saint Joseph, Michigan, 49085

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Corewell Health Lakeland Hospitals - Saint Joseph Hospital

Saint Joseph, Michigan, 49085

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Henry Ford Health Providence Southfield Hospital

Southfield, Michigan, 48075

Recruiting
Site Public Contact · Contact
248-849-5332kfife3@hfhs.org
Adam M. Forman · Principal Investigator

Munson Medical Center

Traverse City, Michigan, 49684

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Corewell Health Beaumont Troy Hospital

Troy, Michigan, 48085

Recruiting
Site Public Contact · Contact
248-551-7695
Andrew A. Muskovitz · Principal Investigator

Henry Ford Health Warren Hospital

Warren, Michigan, 48093

Recruiting
Site Public Contact · Contact
313-343-3166kforman1@hfhs.org
Elie G. Dib · Principal Investigator

Henry Ford Madison Heights Hospital - Breast

Warren, Michigan, 48093

Recruiting
Site Public Contact · Contact
313-343-3166kforman1@hfhs.org
Elie G. Dib · Principal Investigator

Henry Ford Warren Hospital - GLCMS

Warren, Michigan, 48093

Recruiting
Site Public Contact · Contact
313-343-3166kforman1@hfhs.org
Elie G. Dib · Principal Investigator

University of Michigan Health - West

Wyoming, Michigan, 49519

Recruiting
Site Public Contact · Contact
616-391-1230crcwm-regulatory@crcwm.org
Kathleen Y. Butler · Principal Investigator

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus

Ypsilanti, Michigan, 48197

Recruiting
Site Public Contact · Contact
734-712-7251MCRCwebsitecontactform@stjoeshealth.org
Elie G. Dib · Principal Investigator

Sanford Joe Lueken Cancer Center

Bemidji, Minnesota, 56601

Recruiting
Site Public Contact · Contact
218-333-5000OncologyClinicalTrialsFargo@sanfordhealth.org
Daniel Almquist · Principal Investigator

Essentia Health Saint Joseph's Medical Center

Brainerd, Minnesota, 56401

Recruiting
Site Public Contact · Contact
218-786-3308CancerTrials@EssentiaHealth.org
Bret E. Friday · Principal Investigator

Mercy Hospital

Coon Rapids, Minnesota, 55433

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
David M. King · Principal Investigator

Essentia Health - Deer River Clinic

Deer River, Minnesota, 56636

Recruiting
Site Public Contact · Contact
218-786-3308CancerTrials@EssentiaHealth.org
Bret E. Friday · Principal Investigator

Essentia Health Cancer Center

Duluth, Minnesota, 55805

Recruiting
Site Public Contact · Contact
218-786-3308CancerTrials@EssentiaHealth.org
Bret E. Friday · Principal Investigator

Fairview Southdale Hospital

Edina, Minnesota, 55435

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
David M. King · Principal Investigator

Essentia Health Hibbing Clinic

Hibbing, Minnesota, 55746

Recruiting
Site Public Contact · Contact
218-786-3308
Bret E. Friday · Principal Investigator

Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
David M. King · Principal Investigator

Minneapolis VA Medical Center

Minneapolis, Minnesota, 55417

Recruiting
Site Public Contact · Contact
612-467-2800
Aditi Singh · Principal Investigator

Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
David M. King · Principal Investigator

Regions Hospital

Saint Paul, Minnesota, 55101

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
David M. King · Principal Investigator

United Hospital

Saint Paul, Minnesota, 55102

Recruiting
Site Public Contact · Contact
952-993-1517mmcorc@healthpartners.com
David M. King · Principal Investigator

Essentia Health Sandstone

Sandstone, Minnesota, 55072

Recruiting
Site Public Contact · Contact
218-786-3308CancerTrials@EssentiaHealth.org
Bret E. Friday · Principal Investigator

Essentia Health Virginia Clinic

Virginia, Minnesota, 55792

Recruiting
Site Public Contact · Contact
218-786-3308CancerTrials@EssentiaHealth.org
Bret E. Friday · Principal Investigator

Baptist Memorial Hospital and Cancer Center-Golden Triangle

Columbus, Mississippi, 39705

Recruiting
Site Public Contact · Contact
901-226-1366BCCclintrials@bmhcc.org
Osarenren Ogbeide · Principal Investigator

Baptist Cancer Center-Grenada

Grenada, Mississippi, 38901

Recruiting
Site Public Contact · Contact
901-226-1366BCCclintrials@bmhcc.org
Osarenren Ogbeide · Principal Investigator

Baptist Memorial Hospital and Cancer Center-Union County

New Albany, Mississippi, 38652

Recruiting
Site Public Contact · Contact
901-226-1366BCCclintrials@bmhcc.org
Osarenren Ogbeide · Principal Investigator

Baptist Memorial Hospital and Cancer Center-Oxford

Oxford, Mississippi, 38655

Recruiting
Site Public Contact · Contact
901-226-1366BCCclintrials@bmhcc.org
Osarenren Ogbeide · Principal Investigator

Baptist Memorial Hospital and Cancer Center-Desoto

Southhaven, Mississippi, 38671

Recruiting
Site Public Contact · Contact
901-226-1366BCCclintrials@bmhcc.org
Osarenren Ogbeide · Principal Investigator

Mercy Oncology and Hematology - Clayton-Clarkson

Ballwin, Missouri, 63011

Recruiting
Site Public Contact · Contact
888-446-3729
Jay W. Carlson · Principal Investigator

University Health Truman Medical Center

Kansas City, Missouri, 64108

Recruiting
Site Public Contact · Contact
816-404-4375
Gary C. Doolittle · Principal Investigator

Mercy Hospital South

St Louis, Missouri, 63128

Recruiting
Site Public Contact · Contact
314-525-6042Danielle.Werle@mercy.net
Jay W. Carlson · Principal Investigator

Mercy Hospital Saint Louis

St Louis, Missouri, 63141

Recruiting
Site Public Contact · Contact
314-251-7066
Jay W. Carlson · Principal Investigator

Community Hospital of Anaconda

Anaconda, Montana, 59711

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Billings Clinic Cancer Center

Billings, Montana, 59101

Recruiting
Site Public Contact · Contact
800-996-2663research@billingsclinic.org
John M. Schallenkamp · Principal Investigator

Saint Vincent Frontier Cancer Center

Billings, Montana, 59102

Recruiting
Site Public Contact · Contact
800-648-6274
Patrick W. Cobb · Principal Investigator

Bozeman Health Deaconess Hospital

Bozeman, Montana, 59715

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Benefis Sletten Cancer Institute

Great Falls, Montana, 59405

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Logan Health Medical Center

Kalispell, Montana, 59901

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

Community Medical Center

Missoula, Montana, 59804

Recruiting
Site Public Contact · Contact
406-969-6060mccinfo@mtcancer.org
John M. Schallenkamp · Principal Investigator

University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106

Recruiting
Site Public Contact · Contact
505-925-0348HSC-ClinicalTrialInfo@salud.unm.edu
Moises Harari-Turquie · Principal Investigator

Roswell Park Cancer Institute

Buffalo, New York, 14263

Recruiting
Site Public Contact · Contact
800-767-9355askroswell@roswellpark.org
Bailey G. Fitzgerald · Principal Investigator

Montefiore Medical Center-Einstein Campus

The Bronx, New York, 10461

Recruiting
Site Public Contact · Contact
718-379-6866eskwak@montefiore.org
Tamar B. Nobel · Principal Investigator

Montefiore Medical Center-Weiler Hospital

The Bronx, New York, 10461

Recruiting
Site Public Contact · Contact
718-379-6866eskwak@montefiore.org
Tamar B. Nobel · Principal Investigator

Montefiore Medical Center - Moses Campus

The Bronx, New York, 10467

Recruiting
Site Public Contact · Contact
718-379-6866eskwak@montefiore.org
Tamar B. Nobel · Principal Investigator

James J Peters VA Medical Center

The Bronx, New York, 10468

Recruiting
Site Public Contact · Contact
718-584-9000kl2965@cumc.columbia.edu
Susan E. Bates · Principal Investigator

Duke Cancer Center Cary

Cary, North Carolina, 27518

Recruiting
Site Public Contact · Contact
NCTNStudyTeam@dm.duke.edu
Joel Rivera Concepcion · Principal Investigator

Duke University Medical Center

Durham, North Carolina, 27710

Recruiting
Site Public Contact · Contact
888-275-3853
Joel Rivera Concepcion · Principal Investigator

FirstHealth of the Carolinas-Moore Regional Hospital

Pinehurst, North Carolina, 28374

Recruiting
Site Public Contact · Contact
910-715-3500jcwilliams@firsthealth.org
Charles S. Kuzma · Principal Investigator

Duke Cancer Center Raleigh

Raleigh, North Carolina, 27609

Recruiting
Site Public Contact · Contact
NCTNStudyTeam@dm.duke.edu
Joel Rivera Concepcion · Principal Investigator

Sanford Bismarck Medical Center

Bismarck, North Dakota, 58501

Recruiting
Site Public Contact · Contact
701-323-5760OncologyClinicalTrialsFargo@sanfordhealth.org
Daniel Almquist · Principal Investigator

Essentia Health Cancer Center-South University Clinic

Fargo, North Dakota, 58103

Recruiting
Site Public Contact · Contact
218-786-3308CancerTrials@EssentiaHealth.org
Bret E. Friday · Principal Investigator

Sanford Broadway Medical Center

Fargo, North Dakota, 58122

Recruiting
Site Public Contact · Contact
701-323-5760OncologyClinicalTrialsFargo@sanfordhealth.org
Daniel Almquist · Principal Investigator

Sanford Roger Maris Cancer Center

Fargo, North Dakota, 58122

Recruiting
Site Public Contact · Contact
701-234-6161OncologyClinicalTrialsFargo@sanfordhealth.org
Daniel Almquist · Principal Investigator

Aultman Health Foundation

Canton, Ohio, 44710

Recruiting
Site Public Contact · Contact
330-363-7274ClinicalReserachDept@aultman.com
Raza A. Khan · Principal Investigator

Miami Valley Hospital South

Centerville, Ohio, 45459

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Tarek M. Sabagh · Principal Investigator

Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210

Recruiting
Site Public Contact · Contact
800-293-5066Jamesline@osumc.edu
Dwight H. Owen · Principal Investigator

Miami Valley Hospital

Dayton, Ohio, 45409

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Tarek M. Sabagh · Principal Investigator

Miami Valley Hospital North

Dayton, Ohio, 45415

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Tarek M. Sabagh · Principal Investigator

Atrium Medical Center-Middletown Regional Hospital

Franklin, Ohio, 45005-1066

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Tarek M. Sabagh · Principal Investigator

Miami Valley Cancer Care and Infusion

Greenville, Ohio, 45331

Recruiting
Site Public Contact · Contact
937-569-7515
Tarek M. Sabagh · Principal Investigator

Upper Valley Medical Center

Troy, Ohio, 45373

Recruiting
Site Public Contact · Contact
937-528-2900clinical.trials@daytonncorp.org
Tarek M. Sabagh · Principal Investigator

University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104

Recruiting
Site Public Contact · Contact
405-271-8777ou-clinical-trials@ouhsc.edu
Nirmal Choradia · Principal Investigator

Providence Hood River Memorial Hospital

Hood River, Oregon, 97031

Recruiting
Site Public Contact · Contact
503-215-1979canrsrchstudies@provdience.org
Charles W. Drescher · Principal Investigator

Providence Newberg Medical Center

Newberg, Oregon, 97132

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Charles W. Drescher · Principal Investigator

Providence Willamette Falls Medical Center

Oregon City, Oregon, 97045

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Charles W. Drescher · Principal Investigator

Providence Portland Medical Center

Portland, Oregon, 97213

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Charles W. Drescher · Principal Investigator

Providence Saint Vincent Medical Center

Portland, Oregon, 97225

Recruiting
Site Public Contact · Contact
503-215-2614CanRsrchStudies@providence.org
Charles W. Drescher · Principal Investigator

Oregon Health and Science University

Portland, Oregon, 97239

Recruiting
Site Public Contact · Contact
503-494-1080trials@ohsu.edu
Jeremy P. Cetnar · Principal Investigator

Lehigh Valley Hospital-Cedar Crest

Allentown, Pennsylvania, 18103

Recruiting
Site Public Contact · Contact
610-402-9543Morgan_M.Horton@lvhn.org
Elie G. Dib · Principal Investigator

Lehigh Valley Hospital - Muhlenberg

Bethlehem, Pennsylvania, 18017

Recruiting
Site Public Contact · Contact
610-402-9543Morgan_M.Horton@lvhn.org
Elie G. Dib · Principal Investigator

Bryn Mawr Hospital

Bryn Mawr, Pennsylvania, 19010

Recruiting
Site Public Contact · Contact
484-476-2649turzoe@mlhs.org
Deric C. Savior · Principal Investigator

Pocono Medical Center

East Stroudsburg, Pennsylvania, 18301

Recruiting
Site Public Contact · Contact
610-402-9543Morgan_M.Horton@lvhn.org
Elie G. Dib · Principal Investigator

UPMC Hillman Cancer Center Erie

Erie, Pennsylvania, 16505

Recruiting
Site Public Contact · Contact
412-864-7716ClinicalResearchServices@upmc.edu
Liza C. Villaruz · Principal Investigator

UPMC Cancer Centers - Arnold Palmer Pavilion

Greensburg, Pennsylvania, 15601

Recruiting
Site Public Contact · Contact
724-838-1900
Liza C. Villaruz · Principal Investigator

UPMC Pinnacle Cancer Center/Community Osteopathic Campus

Harrisburg, Pennsylvania, 17109

Recruiting
Site Public Contact · Contact
717-724-6765klitchfield@PINNACLEHEALTH.org
Liza C. Villaruz · Principal Investigator

Lehigh Valley Hospital-Hazleton

Hazleton, Pennsylvania, 18201

Recruiting
Site Public Contact · Contact
610-402-9543Morgan_M.Horton@lvhn.org
Elie G. Dib · Principal Investigator

UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion

Mechanicsburg, Pennsylvania, 17050

Recruiting
Site Public Contact · Contact
412-389-5208haneydl@upmc.edu
Liza C. Villaruz · Principal Investigator

Riddle Memorial Hospital

Media, Pennsylvania, 19063

Recruiting
Site Public Contact · Contact
484-476-2649turzoe@mlhs.org
Deric C. Savior · Principal Investigator

UPMC Hillman Cancer Center - Monroeville

Monroeville, Pennsylvania, 15146

Recruiting
Site Public Contact · Contact
412-864-7716ClinicalResearchServices@upmc.edu
Liza C. Villaruz · Principal Investigator

Paoli Memorial Hospital

Paoli, Pennsylvania, 19301

Recruiting
Site Public Contact · Contact
484-476-2649turzoe@mlhs.org
Deric C. Savior · Principal Investigator

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107

Recruiting
Site Public Contact · Contact
215-600-9151ONCTrialNow@jefferson.edu
Sarah W. Gordon · Principal Investigator

Jefferson Torresdale Hospital

Philadelphia, Pennsylvania, 19114

Recruiting
Site Public Contact · Contact
215-600-9151ONCTrialNow@jefferson.edu
Sarah W. Gordon · Principal Investigator

University of Pittsburgh Cancer Institute (UPCI)

Pittsburgh, Pennsylvania, 15232

Recruiting
Site Public Contact · Contact
412-647-8073
Liza C. Villaruz · Principal Investigator

Reading Hospital

West Reading, Pennsylvania, 19611

Recruiting
Site Public Contact · Contact
610-988-9323
Terrence P. Cescon · Principal Investigator

Lankenau Medical Center

Wynnewood, Pennsylvania, 19096

Recruiting
Site Public Contact · Contact
484-476-2649turzoe@mlhs.org
Deric C. Savior · Principal Investigator

Prisma Health Cancer Institute - Spartanburg

Boiling Springs, South Carolina, 29316

Recruiting
Site Public Contact · Contact
864-522-4317Kim.Williams3@prismahealth.org
Ki Y. Chung · Principal Investigator

Prisma Health Cancer Institute - Easley

Easley, South Carolina, 29640

Recruiting
Site Public Contact · Contact
864-522-4317Kim.Williams3@prismahealth.org
Ki Y. Chung · Principal Investigator

Gibbs Cancer Center-Gaffney

Gaffney, South Carolina, 29341

Recruiting
Site Public Contact · Contact
864-560-6104kmertz-rivera@gibbscc.org
Michael Humeniuk · Principal Investigator

Tidelands Georgetown Memorial Hospital

Georgetown, South Carolina, 29440

Recruiting
Site Public Contact · Contact
843-545-5600broe@tidelandshealth.org
Mariam Alexander · Principal Investigator

Prisma Health Cancer Institute - Butternut

Greenville, South Carolina, 29605

Recruiting
Site Public Contact · Contact
864-522-4317Kim.Williams3@prismahealth.org
Ki Y. Chung · Principal Investigator

Prisma Health Cancer Institute - Faris

Greenville, South Carolina, 29605

Recruiting
Site Public Contact · Contact
864-522-4317Kim.Williams3@prismahealth.org
Ki Y. Chung · Principal Investigator

Prisma Health Cancer Institute - Eastside

Greenville, South Carolina, 29615

Recruiting
Site Public Contact · Contact
864-522-4317Kim.Williams3@prismahealth.org
Ki Y. Chung · Principal Investigator

Prisma Health Cancer Institute - Greer

Greer, South Carolina, 29650

Recruiting
Site Public Contact · Contact
864-522-4317Kim.Williams3@prismahealth.org
Ki Y. Chung · Principal Investigator

Gibbs Cancer Center-Pelham

Greer, South Carolina, 29651

Recruiting
Site Public Contact · Contact
864-560-6104kmertz-rivera@gibbscc.org
Michael Humeniuk · Principal Investigator

Prisma Health Cancer Institute - Seneca

Seneca, South Carolina, 29672

Recruiting
Site Public Contact · Contact
864-522-4317Kim.Williams3@prismahealth.org
Ki Y. Chung · Principal Investigator

Spartanburg Medical Center

Spartanburg, South Carolina, 29303

Recruiting
Site Public Contact · Contact
864-560-6104kmertz-rivera@gibbscc.org
Michael Humeniuk · Principal Investigator

SMC Center for Hematology Oncology Union

Union, South Carolina, 29379

Recruiting
Site Public Contact · Contact
864-560-6104kmertz-rivera@gibbscc.org
Michael Humeniuk · Principal Investigator

Sanford Cancer Center Oncology Clinic

Sioux Falls, South Dakota, 57104

Recruiting
Site Public Contact · Contact
605-312-3320OncologyClinicTrialsSF@sanfordhealth.org
Daniel Almquist · Principal Investigator

Sanford USD Medical Center - Sioux Falls

Sioux Falls, South Dakota, 57117-5134

Recruiting
Site Public Contact · Contact
605-312-3320OncologyClinicalTrialsSF@SanfordHealth.org
Daniel Almquist · Principal Investigator

Baptist Memorial Hospital and Cancer Center-Collierville

Collierville, Tennessee, 38017

Recruiting
Site Public Contact · Contact
901-226-1366BCCclintrials@bmhcc.org
Osarenren Ogbeide · Principal Investigator

Baptist Memorial Hospital and Cancer Center-Memphis

Memphis, Tennessee, 38120

Recruiting
Site Public Contact · Contact
901-226-1366BCCclintrials@bmhcc.org
Osarenren Ogbeide · Principal Investigator

Hematology Oncology Associates of Fredericksburg Inc

Fredericksburg, Virginia, 22408

Recruiting
Site Public Contact · Contact
540-371-0079cvaughn@hoafredericksburg.com
Masey M. Ross · Principal Investigator

Centra Alan B Pearson Regional Cancer Center

Lynchburg, Virginia, 24501

Recruiting
Site Public Contact · Contact
434-200-1495Kevin.Patel@centrahealth.com
Masey M. Ross · Principal Investigator

Virginia Cancer Institute

Richmond, Virginia, 23229

Recruiting
Site Public Contact · Contact
804-287-3000smoore@vacancer.com
Masey M. Ross · Principal Investigator

VCU Community Memorial Health Center

South Hill, Virginia, 23970

Recruiting
Site Public Contact · Contact
nemer.elmouallem@vcuhealth.org
Masey M. Ross · Principal Investigator

Swedish Cancer Institute-Edmonds

Edmonds, Washington, 98026

Recruiting
Site Public Contact · Contact
206-215-2343PCRC-NCORP@Swedish.org
Charles W. Drescher · Principal Investigator

Swedish Cancer Institute-Issaquah

Issaquah, Washington, 98029

Recruiting
Site Public Contact · Contact
206-215-2343PCRC-NCORP@Swedish.org
Charles W. Drescher · Principal Investigator

Swedish Medical Center-First Hill

Seattle, Washington, 98122

Recruiting
Site Public Contact · Contact
206-215-2343PCRC-NCORP@Swedish.org
Charles W. Drescher · Principal Investigator

Edwards Comprehensive Cancer Center

Huntington, West Virginia, 25701

Recruiting
Site Public Contact · Contact
304-399-6566Christina.Cole@chhi.org
Toni O. Pacioles · Principal Investigator

Langlade Hospital and Cancer Center

Antigo, Wisconsin, 54409

Recruiting
Site Public Contact · Contact
715-623-9869Juli.Alford@aspirus.org
Andrew J. Huang · Principal Investigator

Duluth Clinic Ashland

Ashland, Wisconsin, 54806

Recruiting
Site Public Contact · Contact
218-786-3308CancerTrials@EssentiaHealth.org
Bret E. Friday · Principal Investigator

Marshfield Medical Center-EC Cancer Center

Eau Claire, Wisconsin, 54701

Recruiting
Site Public Contact · Contact
800-782-8581oncology.clinical.trials@marshfieldresearch.org
Dean A. Delmastro · Principal Investigator

Saint Vincent Hospital Cancer Center Green Bay

Green Bay, Wisconsin, 54301

Recruiting
Site Public Contact · Contact
920-433-8889WI_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Saint Vincent Hospital Cancer Center at Saint Mary's

Green Bay, Wisconsin, 54303

Recruiting
Site Public Contact · Contact
920-433-8889wi_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Gundersen Lutheran Medical Center

La Crosse, Wisconsin, 54601

Recruiting
Site Public Contact · Contact
608-775-2385cancerctr@gundersenhealth.org
David E. Marinier · Principal Investigator

Aspirus Medford Hospital

Medford, Wisconsin, 54451

Recruiting
Site Public Contact · Contact
715-847-2353Beth.Knetter@aspirus.org
Andrew J. Huang · Principal Investigator

ProHealth D N Greenwald Center

Mukwonago, Wisconsin, 53149

Recruiting
Site Public Contact · Contact
research.institute@phci.org
Timothy R. Wassenaar · Principal Investigator

ProHealth Oconomowoc Memorial Hospital

Oconomowoc, Wisconsin, 53066

Recruiting
Site Public Contact · Contact
262-928-7878
Timothy R. Wassenaar · Principal Investigator

Saint Vincent Hospital Cancer Center at Oconto Falls

Oconto Falls, Wisconsin, 54154

Recruiting
Site Public Contact · Contact
920-433-8889WI_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Aspirus Cancer Care - James Beck Cancer Center

Rhinelander, Wisconsin, 54501

Recruiting
Site Public Contact · Contact
715-847-2353Beth.Knetter@aspirus.org
Andrew J. Huang · Principal Investigator

Saint Vincent Hospital Cancer Center at Sheboygan

Sheboygan, Wisconsin, 53081

Recruiting
Site Public Contact · Contact
920-433-8889wi_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Sheboygan Physicians Group

Sheboygan, Wisconsin, 53081

Recruiting
Site Public Contact · Contact
920-433-8889wi_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

Aspirus Cancer Care - Stevens Point

Stevens Point, Wisconsin, 54481

Recruiting
Site Public Contact · Contact
715-847-2353Beth.Knetter@aspirus.org
Andrew J. Huang · Principal Investigator

Saint Vincent Hospital Cancer Center at Sturgeon Bay

Sturgeon Bay, Wisconsin, 54235-1495

Recruiting
Site Public Contact · Contact
920-433-8889wi_research_admin@hshs.org
Matthew L. Ryan · Principal Investigator

UW Cancer Center at ProHealth Care

Waukesha, Wisconsin, 53188

Recruiting
Site Public Contact · Contact
262-928-5539Chanda.miller@phci.org
Timothy R. Wassenaar · Principal Investigator

Aspirus Regional Cancer Center

Wausau, Wisconsin, 54401

Recruiting
Site Public Contact · Contact
877-405-6866
Andrew J. Huang · Principal Investigator

Aspirus Cancer Care - Wisconsin Rapids

Wisconsin Rapids, Wisconsin, 54494

Recruiting
Site Public Contact · Contact
715-422-7718
Andrew J. Huang · Principal Investigator