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RecruitingObservational

Presence of Barrett's Esophagitis in a Cohort of People With Eating Disorders Who Engage in Purging Behaviors: A Pilot Study

NCT ID: NCT06532734Sponsor: Denver Health and Hospital AuthorityLast updated: 2025-12-10

Summary

To better define the presence of Barrett's esophagus (BE) via non-endoscopic testing in an eating disorder cohort with purging (vomiting/rumination) behaviors

Detailed description

A prospective cohort study to assess the presence of BE in those with purging behaviors from their eating disorders has not been completed. There are multiple case reports describing a younger population not meeting typical screening guidelines whom developed this condition. To better define the presence of Barrett's esophagus (BE) via non-endoscopic testing in an eating disorder cohort with purging (vomiting/rumination) behaviors. Individuals with severe forms of eating disorders with purging and ruminating behaviors not meeting the current screening guidelines for BE will still test positive for BE.

Arms & interventions

  • DeviceEsoGuard

    device used to collect esophageal cell samples to test for the presence of abnormal cells which may indicate a dx of Barrett's esophagitis.

Outcome measures

Primary

  • Number of patients positive for BE

    Individuals with severe forms of eating disorders with purging and ruminating behaviors not meeting a current screening guidelines for BE will test positive for BE

    Time frame: 12 months

Eligibility criteria

Sex: AllAge: 18 Years to 65 YearsHealthy volunteers: No
Inclusion Criteria: * Patients diagnosed with an eating disorder diagnosis that includes purging history * Ages 18-65 * Purging history =\>5 years * Purging or rumination at a minimum of once daily upon admission. * Admission to the ACUTE Center for Eating Disorders and Severe Malnutrition Exclusion Criteria: * Any eating disorder diagnosis that does not include purging behaviors * Ages under 18 and over 65 * Patients who otherwise meet the current ACG screening guidelines (chronic GERD and 3 or more risk factors for Barrett's mentioned in the Background) * Received mandated care at time of enrollment * Inability to consent to participate in the research

Study locations (3)

ACUTE Center for Eating Disorders and Severe Malnutrition

Denver, Colorado, 80204

Recruiting
Marina J Foster, BA · Contact
Alllison Nitsch, MD · Contact

Denver Health and Hospital Authority

Denver, Colorado, 80204

Recruiting
Marina Foster · Contact

Denver Health and Hospital Authority

Denver, Colorado, 80204

Recruiting
Marina J Foster, BA · Contact
Alllison Nitsch, MD · Contact
Allison Nitsch, MD · Principal Investigator
Barrett's Esophagitis in Anorexia Nervosa Binge/Purge Subtype | Cancerify