Cancerify Logo
Log inSign up
Back to clinical trials
RecruitingObservational

Patient Descriptors Of Cancer-Related Fatigue: A Mixed Methods Pilot Study Of Cancer Survivors

NCT ID: NCT06634381Sponsor: Wake Forest University Health SciencesLast updated: 2026-02-02

Summary

The purpose of this research study is to better understand how cancer-related fatigue affects patients and how it's discussed with providers. This information will be used to develop an educational resource (visual aid poster) that could help individuals and their providers talk about cancer-related fatigue and which may help individuals better manage this symptom.

Detailed description

This is a mixed methods cross-sectional pilot study. The target population is adults ≥ 18 years of age who have been diagnosed with cancer, have completed anti-cancer treatment more than six months ago, have no current detectable evidence of cancer, and are experiencing cancer-related fatigue. Participation in this research will involve completion of a six-minute walk test, survey completion, two virtual video interviews, and potentially one additional virtual interview. The interviews will include two 45 minutes for survivors and one 30-minute interview for clinicians. An additional 30-minute interview will be conducted for each survivor and clinician group.

Arms & interventions

  • BehavioralCRF Visual Aid

    After all qualitative interviews and associated quantitative data analysis are complete, the visual aid will be created to illustrate, through a type of Venn Diagram, how the data are related.

Outcome measures

Primary

  • Domains reflecting cancer-related fatigue (CRF) experiences in cancer survivors

    A domain is a topic that people talk about that has sub-items characterizing the distinct features and levels of importance within the domain. Using qualitative analysis, evaluation of how survivors think and talk about CRF to generate domain classifications of language. Domain is a categorical variable.

    Time frame: Seven months from baseline

Secondary

  • Qualitative themes derived from open-ended interviews of clinicians

    Time frame: Five months from screening

  • Domains reflecting CRF experiences in cancer survivors

    Time frame: Seven months from baseline

  • Appropriateness of the visual aid to alleviate survivor-clinician communication barriers

    Time frame: Eleven months from baseline

Eligibility criteria

Sex: AllAge: 18 Years and olderHealthy volunteers: No
Inclusion Criteria: * Ability to comply with study procedures for the duration of the study Survivors: * Written informed consent and HIPAA authorization for release of personal information * Ability to read/write, understand and converse in English without the need for an interpreter * Men and women aged ≥ 18 years at the time of consent * White or Caucasian, Black or African American, or Hispanic or Latino/a * History of at least one visit for the purpose of monitoring long term care post curative treatment at LCH and/or the Charlotte or Winston-Salem campuses of AHWFBCCC * Completed curative treatment \> 6 months ago for any cancer type, with no detectable evidence of cancer * Self-reported fatigue score of ≥ 4 on the Numerical Rating Scale Clinicians: \- Currently see oncology patients (any cancer type) for survivorship care at LCH and/or the Charlotte or Winston-Salem campuses of AHWFBCCC Exclusion Criteria: Survivors: * Continuing maintenance therapy or other cancer-related treatment (i.e. immunotherapy or hormonal therapy) * History of or current severe or untreated depression * Hemoglobin \<11g/dL at last CBC SOC lab collection * History/diagnosis of dementia * Factors or conditions, for which participation may (1) not be in the best interest or (2) interfere with study assessment results (e.g. medical comorbidities, primary brain tumor/metastases) * No access to internet/Wi-Fi Clinicians: \- None

Study locations (3)

Levine Childrens Hospital Pediatric Cancer and Blood Disorders

Charlotte, North Carolina, 28203

Recruiting
Dori Beeler, PhD · Principal Investigator

Levine Cancer Institute

Charlotte, North Carolina, 28204

Recruiting
Dori Beeler, PhD · Principal Investigator

Wake Forest Baptist Comprehensive Cancer Center

Winston-Salem, North Carolina, 27157

Recruiting
Sarah Birken, PhD · Contact
Sarah Birken, PhD · Principal Investigator
Patient Descriptors Of Cancer-Related Fatigue: A Mixed Methods Pilot Study Of Cancer Survivors | Cancerify