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RecruitingInterventional

Pilot Study of Mindset Moments Among Adolescent and Young Adult Cancer Survivors

NCT ID: NCT06732375Sponsor: Duke UniversityLast updated: 2026-05-06

Summary

The purpose of this study is to evaluate the feasibility and acceptability of the Mindset Moments™ (MM™) program in managing psychological distress and resiliency in adolescent and young adult cancer survivors. Study participation will involve attending 8 weekly, one hour, live online group sessions and completing daily 5 minute activities such as guided imageries and CBT check in within the app. Participants will also be asked to complete an online survey at the time of enrollment and at 4 and 8 weeks.

Arms & interventions

  • BehavioralMindset Moments

    MM™ includes: 1) CBT; 2) resilience training; 3) mindfulness-based stress reduction; 4) peer support; and 5) family conversations delivered in small virtual groups, with a "mentor" who facilitates resilience-building conversations prompted from "Skill of the Week" lessons.

Outcome measures

Primary

  • Anxiety as measured by the Patient-Reported Outcomes Measurement Information System (PROMIS)

    8-measure short form to assess the severity of anxiety symptoms within the Patient-Reported Outcomes Measurement Information System (PROMIS) framework. The total score ranges from 8 to 40, where a higher score indicates greater anxiety.

    Time frame: 8 weeks

Secondary

  • Depression as measured by the Patient-Reported Outcomes Measurement Information System (PROMIS)

    Time frame: 8 weeks

  • Symptoms of Post-Traumatic Stress Disorder (PTSD) as measured by the PCL-5

    Time frame: 8 weeks

  • Distress as measured by the National Comprehensive Cancer Network's (NCCN) Distress Thermometer (DT)

    Time frame: 8 weeks

  • Ability to deal with stressful situations as measured by the Shift-and-Persist Scale

    Time frame: 8 weeks

Eligibility criteria

Sex: AllAge: 19 Years to 25 YearsHealthy volunteers: Yes
Inclusion Criteria: * 19-25 years of age * Prior AYA cancer diagnosis * Completed primary treatment for their cancer * Score of 3 or above on the Distress Thermometer at the time of recruitment Exclusion Criteria: * Individuals without legal capacity to give consent * Individuals who are not fluent in reading, writing, and speaking English

Study locations (1)

Duke Cancer Institute

Durham, North Carolina, 27710

Recruiting
Sophia K Smith, PhD, MSW · Contact