Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening (MATCHES)
Summary
This innovative Multilevel Action Toward Colorectal Cancer (CRC) and Hepatitis C Virus (HCV) Education and Screening (MATCHES) intervention aims to promote concurrent HCV and CRC screening among FQHC patients ages 45-75.
Detailed description
While this is a multi-level intervention study, only information related to the patient-level intervention is being reported for the purposes ClinicalTrials.gov.
Arms & interventions
- BehavioralMATCHES
Participants will be asked to complete a survey with specific topics including Hepatitis C (HCV) and Colorectal (CRC) knowledge and health beliefs, screening intentions and demographic characteristics. Participants will be provided with education intervention materials (for example, a booklet) either in-person or via mail, access to free stool-based CRC screening, and access to free HCV screening. Approximately 1-2 weeks after receiving the education materials, participants will be asked to complete a post-intervention survey about the same specific topics (for example, HCV and CRC knowledge, HCV and CRC health beliefs, HCV and CRC screening intentions, healthcare experiences, perceptions of the educational materials) over the phone with a trained study staff. Participants with a positive HCV screening and/or CRC screening result will be navigated to follow-up care as needed.
Outcome measures
Primary
Screening Uptake for Hepatitis C Virus (HCV) and Colorectal Cancer (CRC)
Screening Uptake will be measured by the number of participants who complete both CRC and HCV screening documented via Electronic Health Record (EHR) at 12 months post-intervention.
Time frame: Up to 12 Months
Secondary
Screening Completion for Hepatitis C Virus (HCV)
Time frame: Up to 41 Months
Screening Completion for Colorectal Cancer (CRC)
Time frame: Up to 41 Months
Screening Test Results for Hepatitis C (HCV)
Time frame: Up to 41 Months
Screening Test Results for Colorectal Cancer (CRC)
Time frame: Up to 41 Months
Completion of repeat CRC Screening
Time frame: Up to 41 Months
Eligibility criteria
Study locations (1)
Moffitt Cancer Center
Tampa, Florida, 33612
References
- Abdulla R, Boxtha C, Courtney EP, Anyanwu OA, Sutton SK, Chung-Bridges K, Kassaye HG, Philippe E, Mudon KA, Frias E, Parras D, Avrilien N, Friedman M, Turner K, Coronado GD, Champion VL, Tobin JN, Vadaparampil ST, Gwede CK, Christy SM. Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening (MATCHES): Study protocol for a hybrid 1 stepped-wedge multibehavioral randomized trial. Contemp Clin Trials. 2026 Apr;163:108256. doi: 10.1016/j.cct.2026.108256. Epub 2026 Feb 13.(PubMed)