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RecruitingInterventionalPhase 3

Erector Spinae Versus Intercostal Nerve Blocks With Liposomal Bupivacaine for Analgesia in Thoracic Surgery

NCT ID: NCT06810375Sponsor: George Washington UniversityLast updated: 2026-04-09

Summary

This clinical trial compares efficacy in postoperative pain management in thoracic surgery between erector spinae block versus liposomal bupivacaine injections.

Arms & interventions

  • DrugErector Spinae (ESP) Block with Bupivacaine (Marcaine®)

    preoperative erector spinae block with bupivacaine (Marcaine®)

  • DrugIntercostal nerve block

    intraoperative intercostal nerve block with liposomal bupivacaine (Exparel®)

Outcome measures

Primary

  • Postoperative pain control assessment

    Study team will assess postoperative pain scores at 6, 12, 24 and 48 hours (Minimum numerical pain score of 0 and a maximum of 10)

    Time frame: Up to 48 hours postoperatively

  • Morphine equivalent assessment

    Study team will collect information on all administered pain medications to calculate morphine equivalents

    Time frame: Up to 72 hours postoperatively

Secondary

  • Postoperative pain control assessment

    Time frame: Up to 72 hours postoperatively

Eligibility criteria

Sex: AllAge: 18 Years to 90 YearsHealthy volunteers: No
Inclusion Criteria: * Video assisted pulmonary resection, pleurodesis or decortication Exclusion Criteria: * Allergy to local anesthetics * Patient undergoing bilateral surgery * Surgery is emergent as deemed by the principal investigator

Study locations (1)

The George Washington University Hospital

Washington D.C., District of Columbia, 20037

Recruiting
Eduard Shaykhinurov · Contact
202-203-8960eshaykhinurov@mfa.gwu.edu
Erector Spinae Versus Intercostal Nerve Blocks With Liposomal Bupivacaine for Analgesia in Thoracic Surgery | Cancerify