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RecruitingObservational

Exploration of HRQOL and Urinary Outcomes Following Partial Cystectomy

NCT ID: NCT06891209Sponsor: Mayo ClinicLast updated: 2026-03-10

Summary

This study explores and compares health-related quality of life and urinary outcomes in postoperative partial cystectomy and matched radical cystectomy patients.

Detailed description

PRIMARY OBJECTIVES: I. Explore and compare urinary outcomes in postoperative partial cystectomy patients and matched radical cystectomy patients through patient-filled questionnaires. II. Explore and compare health related quality of life in postoperative partial cystectomy and matched radical cystectomy patients using patient-filled questionnaires. III. Explore the relationship of patient-specific characteristics, ranging from demographic characteristics and clinicopathologic characteristics, on variation in HRQOL and urinary outcomes among the partial cystectomy and radical cystectomy cohorts. OUTLINE: This is an observational study. Patients complete questionnaires and have their medical records reviewed on study.

Arms & interventions

  • OtherNon-Interventional Study

    Non-interventional study

Outcome measures

Primary

  • Health-related quality of life - EORTC QLQ-C30

    Assessed using the EORTC Core Quality of Life questionnaire (EORTC QLQ-C30), which is designed to measure cancer patients' physical, psychological and social functions. It is a 30-item questionnaire related to symptoms and activities during the past week. Responses are recorded on a scale of 1-4 where 1=not at all, 2=a little, 3=quite a bit, and 4=very much. Scores among partial cystectomy patients will be compared to radical cystectomy patients.

    Time frame: Up to 1 year

  • Self-reported urinary outcomes

    Assessed using the EORTC Quality of Life Questionnaire - Muscle Invasive Bladder Cancer (EORTC QLQ-BLM30), a 30-item questionnaire related to general symptoms experienced during the past week or during the past 4 weeks. Responses are recorded on a scale of 1-4 where 1=not at all, 2=a little, 3=quite a bit, and 4=very much. Scores among partial cystectomy patients will be compared to radical cystectomy patients.

    Time frame: Up to 1 year

Eligibility criteria

Sex: AllAge: 18 Years and olderHealthy volunteers: No
Inclusion Criteria: * Currently living partial cystectomy patients in Mayo Urology's cystectomy registry and patients undergoing radical or partial cystectomy * Matched 2:1 living radical cystectomy to partial cystectomy patients * Either urothelial or non-urothelial histology Exclusion Criteria: * Partial cystectomy patients that underwent subsequent radical cystectomy

Study locations (1)

Mayo Clinic in Rochester

Rochester, Minnesota, 55905

Recruiting
Clinical Trials Referral Office · Contact
855-776-0015mayocliniccancerstudies@mayo.edu
Gianni Morales Martinez · Contact
507-538-1447moralesmartnez.gianni@mayo.edu
Vidit Sharma, MD · Principal Investigator
Exploration of HRQOL and Urinary Outcomes Following Partial Cystectomy | Cancerify