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RecruitingObservational

Evaluating the Implementation and Effectiveness of the BJC-Pink and Pearl Project on Lung Cancer Screening

NCT ID: NCT06898333Sponsor: Washington University School of MedicineLast updated: 2026-05-19

Summary

The investigators proposal is ripe for executing as the investigators seek to leverage this "natural experiment" initiated by the BJC health system to evaluate the effectiveness of the Pink \& Pearl Campaign as an implementation strategy to promote lung cancer screening (LCS) uptake among LCS-eligible women undergoing mammography at BJC West County. This evaluation is grounded in the Integrated Screening Action Model that depicts individual- and environmental-level influences on the screening behavior process. Using an explanatory sequential mixed methods design, which combines both quantitative and qualitative approaches, the research questions and specific aims for this proposal are to: a) evaluate the baseline prevalence of LCS among LCS-eligible women; b) assess whether the Pink \& Pearl Campaign increases referrals and uptake/ completion of LCS among LCS-eligible women undergoing screening mammography; and c) evaluate individual and environmental factors influencing LCS uptake, and implementation outcomes of the campaign. These implementation outcomes will help identify whether the campaign was put in place successfully or not. This proposal will inform strategies for integrating cancer screening programs to improve poorly performing programs like LCS.

Arms & interventions

Outcome measures

Primary

  • Prevalence of LCS-eligible women who opt-in to, and successfully, complete LCS mammography and opt-in to lung cancer screening

    Time frame: At baseline

  • Number of women screened for LCS

    Time frame: At 3 months

  • Number of women screened for LCS

    Time frame: At 6 months

  • Feasibility of Pink and Pearl project

    Feasibility is defined as the extent to which the strategy is suitable for routine use in a setting. Information on the feasibility of the Pink and Pearl campaign from healthcare providers will be collected using in-depth interviewing.

    Time frame: At 6 months

  • Acceptability of Pink and Pearl project

    Acceptability is defined as the perception that the strategy is agreeable or satisfactory. Information on the acceptability of the Pink and Pearl campaign from healthcare providers will be collected using in-depth interviewing.

    Time frame: At 6 months

  • Appropriateness of Pink and Pearl project

    Appropriateness is defined as the perceived fit, relevance, or compatibility of the strategy or practice for a given setting. Information on the appropriateness of the Pink and Pearl campaign from healthcare providers will be collected using in-depth interviewing.

    Time frame: At 6 months

Secondary

  • Median time to lung cancer screening

    Time frame: Through completion of follow-up (estimated to be 1 year)

  • Number of women who have a positive lung radiology screening

    Time frame: Through completion of follow-up (estimated to be 1 year)

  • Rate of follow-up for a positive screening examination

    Time frame: Through completion of follow-up (estimated to be 1 year)

  • False positive rates

    Time frame: Through completion of follow-up (estimated to be 1 year)

  • Invasive intervention rate

    Time frame: Through completion of follow-up (estimated to be 1 year)

  • Cancer yield rate

    Time frame: Through completion of follow-up (estimated to be 1 year)

  • Adverse event rate for screening

    Time frame: Through completion of follow-up (estimated to be 1 year)

  • Number of women with varying Stage (1-4) findings in the lung screening radiology report.

    Time frame: Through completion of follow-up (estimated to be 1 year)

  • Cause of death

    Time frame: Through completion of follow-up (estimated to be 1 year)

Eligibility criteria

Sex: AllAge: 18 Years and olderHealthy volunteers: Yes
Inclusion Criteria for Participants: * Undergoing screening mammography * Between the ages of 50-80 years (inclusive) * Reporting a 20 pack-year equivalent of either current smoking history or have quit in the past 15 years * Can speak and understand English * Ability to understand willingness to provide informed consent. Exclusion Criteria for Participants: * Diagnosed with a serious health problem that will likely limit life expectancy (such as previous history of lung cancer, symptoms of lung cancer such as hemoptysis or unexplained weight loss of more than 6.8 kg (15 lb) in the previous year) * Subjects with symptoms of lung cancer should get a diagnostic CT scan * Unable or unwilling to get treatment if lung cancer is found Eligibility Criteria for Providers: * Older than 20 years of age

Study locations (1)

Barnes-Jewish Hospital West County

Creve Coeur, Missouri, 63141

Recruiting
Beryne Odeny, M.D, MPH, Ph.D. · Contact
Beryne Odeny, M.D., MPH, Ph.D. · Principal Investigator
Michelle V Lee, M.D. · Sub Investigator
Aren B Mntzakanian, M.S. · Sub Investigator