Cancerify Logo
Log inSign up
Back to clinical trials
RecruitingInterventional

Creation of an Infrastructure to Support Delivery of mHealth Interventions for Cancer Patients Throughout Florida

NCT ID: NCT06909357Sponsor: H. Lee Moffitt Cancer Center and Research InstituteLast updated: 2026-05-14

Summary

Despite the deleterious impact of smoking upon cancer treatment outcomes, smoking prevalence remains alarmingly high among cancer patients. Thus, reducing smoking by cancer patients is a public health priority, but treatments to date have demonstrated limited efficacy. Mobile health (mHealth) interventions have the potential to improve treatment efficacy while also greatly extending reach. The goal of this infrastructure proposal is to build a resource to facilitate the creation of mHealth tools that address the tobacco treatment needs of cancer patients. This resource, which will be available to researchers throughout Florida, would fill a critical gap in mHealth capacity.

Arms & interventions

  • OtherQuitline Treatment (QT)

    Tobacco Free Florida Quitline. 10-week supply of Combination Nicotine Replacement Therapy (NRT).

  • OtherApp-based Treatment (mHealth)

    Fully automated digitally-delivered smoking cessation intervention targeted to cancer patients. 10-week supply of Combination Nicotine Replacement Therapy (NRT).

Outcome measures

Primary

  • Feasibility: Screening

    Our screening process will be deemed feasible if: 1) ≥ 90% of patients complete the screener, 2) the proportion of patients identified as smokers meets or exceeds the historical self-reported proportions at each institution, 3) the program correctly identifies eligible participants and subsequently presents automated advice to quit, 4) it offers an opportunity to enroll in smoking cessation treatment, and 5) ≥ 30% of eligible patients enroll in treatment.

    Time frame: At Baseline

  • Usability: mHealth

    Usability will be measured 2 ways: I) ≥ 80% will score ≥ 70 on the Systems Usability Scale (SUS), 10-item measure, (scores 0-100) assessing learnability and usability. II) ≥ 80% rate app as easy to use (dichotomous Y/N).

    Time frame: Up to 6 Months

  • Acceptability/Satisfaction: mHealth

    Acceptability/Satisfaction will be measured 4 ways: I) ≥ 80 will score mean ≥ 3.0 Client Satisfaction Questionnaire (CSQ), 8-item measure, (1-4 scale). II) ≥ 80% mostly or extremely satisfied with app. III) ≥ 80% would recommend this app to a friend to quit smoking (dichotomous Y/N). IV) ≥ 80% rate quality of intervention as good or excellent.

    Time frame: Up to 6 Months

Eligibility criteria

Sex: AllAge: 18 Years and olderHealthy volunteers: No
Inclusion Criteria: * ≥18 years of age. * ≥100 lifetime cigarettes. * English-speaking. * Report smoking ≥ 1 cigarette in past 30 days. * Working smartphone. Exclusion Criteria: * Failure to electronically confirm participation within 14 days of randomization via electronic link sent to participant's smartphone. * Currently pregnant or breastfeeding.

Study locations (3)

University of Miami

Coral Gables, Florida, 33146

Recruiting
Tracey Crane, PhD, RDN · Sub Investigator
Taghrid Asfar, MD · Sub Investigator
Frank Penedo, PhD · Sub Investigator

University of Florida

Gainesville, Florida, 23611

Recruiting
Jesse Dallery, PhD · Sub Investigator
Ramzi Salloum, PhD, MA, MBA · Sub Investigator

Moffitt Cancer Center

Tampa, Florida, 33612

Active Not Recruiting

References

  • Sparrock LS, Vidrine JI, Vinci CE, El Naqa IM, Sutton SK, Salloum RG, Dallery J, Crane TE, Penedo FJ, Brockway SJ, Jones SR, Hoogland CE, Reich RR, Gonzalez-Calderon G, Simmons VN, Vidrine DJ. Creation of an mHealth Infrastructure to Support the Development and Delivery of mHealth Interventions: Protocol for Demonstration Projects Addressing Smoking Cessation in Cancer Care. JMIR Res Protoc. 2026 May 29;15:e92288. doi: 10.2196/92288.(PubMed)