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RecruitingInterventional

Longitudinal Screening for Financial Hardship to Improve Outcomes in Patients With Advanced Cancer

NCT ID: NCT06963723Sponsor: Alliance Foundation Trials, LLC.Last updated: 2026-05-12

Summary

The study aims to determine whether monthly remote digital financial hardship screening among adults with advanced/metastatic cancer, undergoing outpatient systemic therapy with non-curative intent, improves patient-centered outcomes, including financial worry, health-related quality of life (HRQoL), symptom burden, patient-reported cancer treatment adherence, and exploratory outcomes of overall survival, patient-reported economic burden, patient-reported support received, patient-reported financial coping strategies, and health insurance literacy.

Detailed description

Financial hardship is a common problem that affects patients treated for advanced cancer and leads to poor outcomes related to financial worry, health related quality of life (HRQoL), symptom burden, treatment adherence, and overall survival. Prior studies have shown that financial navigation may be an effective strategy to attenuate the impact of financial hardship. However, patients and clinicians have identified communication as a key barrier that prevents patients from being connected to sources of financial assistance. To address this critical gap in patient care, and based on strong preliminary data that financial hardship screening may improve patient outcomes, this financial hardship screening intervention will help connect patients to financial navigation resources. It is hypothesized that by connecting patients experiencing financial hardship with financial navigation resources, this intervention will lead to improved patient-centered outcomes.

Arms & interventions

  • OtherFinancial Hardship Screening

    Financial Hardship Screening and Financial Needs Assessment

  • OtherEnhanced Usual Care

    Enhanced Usual Care

Outcome measures

Primary

  • Financial Worry

    Patient-reported financial worry will be measured by the Functional Assessment of Chronic Illness Therapy-Comprehensive Score for Financial Toxicity (FACIT-COST) total scale. Possible score range: 0 to 44, with higher scores indicating better outcomes

    Time frame: 6 months

Secondary

  • Health-related quality of life

    Time frame: 6 months

  • Symptom burden

    Time frame: 6 months

  • Cancer treatment adherence

    Time frame: 6 months

Eligibility criteria

Sex: AllAge: 21 Years and olderHealthy volunteers: No
Inclusion Criteria: 1. Minimum age of 21 2. Understands English and/or Spanish 3. Has a diagnosis of advanced/metastatic cancer 4. Currently undergoing systemic therapy (enteral or parenteral) with non-curative intent 5. Has been receiving treatment for at least 2 months 6. Life expectancy of at least 6 months, in the opinion of the treating oncologist 7. Cognitively able to give informed consent Exclusion Criteria: 1. Under the age of 21 2. Does not understand English or Spanish 3. Has cognitive deficits that would preclude understanding of consent form and/or questionnaires 4. Undergoing treatment with curative intent (e.g., adjuvant chemotherapy for breast, lung, or ovarian cancer, primary curative therapy for testis cancer or lymphoma) 5. Not undergoing systemic therapy (enteral or parenteral) with non-curative intent 6. Receiving treatment for fewer than 2 months 7. Life expectancy is less than 6 months, in the opinion of the treating oncologist

Study locations (6)

Dignity Health

Phoenix, Arizona, 85004

Recruiting
Vamsee Torri, MD · Contact

New Hampshire Oncology-Hematology, PA

Concord, New Hampshire, 03301

Recruiting

Solinsky Center for Cancer Care

Manchester, New Hampshire, 03103

Recruiting

New York City Health and Hospitals

New York, New York, 10004

Recruiting
Debra Ferman, MD · Contact

Sanford Health

Fargo, North Dakota, 58102

Recruiting
Samuel Milanovitch, MD · Contact

Gibbs Cancer Center

Spartanburg, South Carolina, 29303

Recruiting
Amarinthia Curtis, MD · Contact