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RecruitingObservational

Cervical and Endometrial Cancer Screening in Patients Seeking Gender-Affirming Hysterectomy

NCT ID: NCT07075731Sponsor: University of MinnesotaLast updated: 2025-07-20

Summary

This study aims to quantify the rates of cervical cancer screening and endometrial sampling prior to gender-affirming hysterectomy, assess the need for these tests in TGD individuals, and explore patient-centered options for these tests. By assessing the status of testing and correlation with hysterectomy pathology, this study will provide preliminary data on the current state of guideline-concordant care and provide initial evidence for the development of evidence-based guidelines in the future

Arms & interventions

  • OtherNo intervention

    Observational study

Outcome measures

Primary

  • Rates of cervical cancer screening and endometrial sampling in TGD individuals

    Describe the rates of cervical cancer screening and endometrial sampling in TGD individuals undergoing hysterectomy in the MHealth Fairview System between January 2014-June 2024.

    Time frame: Month 36

  • Whether HPV self-testing affects the rates of cervical cancer screening in TGD individuals

    Describe the rates of cervical and endometrial cancer and their precursor lesions on pathology after hysterectomy that was undiagnosed prior to hysterectomy in TGD individuals in the MHealth Fairview System between January 2014-June 2024.

    Time frame: Month 36

Secondary

  • how introducing the option of HPV self-testing affects the rates of cervical cancer screening in TGD individuals undergoing hysterectomy.

    Time frame: Month 36

  • how introducing the option of HPV self-testing affects patient experience

    Time frame: Month 36

Eligibility criteria

Sex: AllAge: 18 Years and older
Inclusion Criteria: * 18 years and older * Able to provide voluntary written consent prior to the performance of any research related activity. Patients who can provide informed consent * Able to understand, speak, read, and write in English * Patients who have undergone hysterectomy, or plan to have a hysterectomy * Patients who are transgender and gender diverse" Exclusion Criteria: * Opted out of research * \<18 years old * Lacks capacity to consent/has diminished capacity to consent * Cannot provide informed consent * Those on the study's community advisory board

Study locations (1)

University of Minnesota

Minneota, Minnesota, 55455

Recruiting
Maria Bunch · Contact
612-624-2018obgynresearch@umn.edu