RecruitingObservational

Qualitative Study on Detection and Treatment of Non-Small Cell Lung Cancer in Patients With a History of Alcohol or Substance Use Disorder

NCT ID: NCT07186699Sponsor: University of Southern CaliforniaLast updated: 2026-04-02

Summary

This study will attempt to identify social facilitators and barriers to detection and treatment of non-small cell lung cancer in order to learn how a history of substance abuse or alcohol use impacts care for non-small cell lung cancer.

Detailed description

PRIMARY OBJECTIVE: I. To identify social facilitators and barriers to detection and treatment of NSCLC by interviewing a diverse group of patients at Keck, Los Angeles General Medical Center, and Norris Cancer Center with alcohol or substance use disorder history. OUTLINE: This is an observational study. Patients participate in a semi-structured interview and may participate in a follow-up focus group interview in which preliminary findings are shared and feedback is elicited on study.

Arms & interventions

OtherNon-Interventional Study
Non-interventional study

Outcome measures

Primary

Thematic saturation
Will use a Danaher framework to approach analyze interview data using NVivo software (NVivo version 11.0, QSR International). Each interview will be analyzed to identify broad themes.
Time frame: Up to 3 years

Eligibility criteria

Sex: AllAge: 18 Years and olderHealthy volunteers: No

Inclusion Criteria: * \* Adults ≥ 18 years of age * Histopathologic or cytologic diagnosis of NSCLC * Received or receiving curative intent treatment (e.g. surgery, radiation therapy, systemic therapy) * History of alcohol use or substance use disorder (other than tobacco use disorder) within the past 10 years, predating the cancer diagnosis * Ability to understand and the willingness to sign a written informed consent * English or Spanish speaking. Due to need to conduct semi-structured interviews which can develop into free-flowing conversations we need both participant and interviewer to be fluent Exclusion Criteria: * Patients with cognitive disability unable to maintain 30-60 minute conversation

Study locations (2)

Los Angeles General Medical Center

Los Angeles, California, 90033

Recruiting

Sandy Tran · Contact

323-865-3935 sandy.tran@med.usc.edu

Brooks V. Udelsman · Principal Investigator