Cancerify Logo
Log inSign up
Back to clinical trials
RecruitingInterventional

Piloting a Virtual Reality-Based, Randomized Controlled Trial of Psychosocial Responses to Neighborhood Physical Disorder

NCT ID: NCT07216534Sponsor: Ohio State University Comprehensive Cancer CenterLast updated: 2026-04-21

Summary

This clinical trial compares virtual reality viewing of an unaltered streetscape versus a digitally manipulated opposite streetscape to assess the psychosocial response in participants. Visible measures of neighborhood factors might be associated with health outcomes and risk factors of those outcomes. Short-term exposure to virtual reality environments representing very high or very low levels of neighborhood physical disorder - presence or absence of garbage/litter, presence or absence of graffiti, presence or absence of an abandoned building, presence or absence of large dumpsters, poor or very well-kept building conditions, poor or very well-kept yard conditions, poor or very well-kept road verge conditions may be a safe and effective way to assess psychosocial response in participants.

Detailed description

PRIMARY OBJECTIVES: I. Compare sympathetic autonomic measures (heart rate variability and skin conductance) between participants viewing, in virtual reality, their streetscape as a digitally manipulated opposite version with respect to physical disorder indicators versus participants viewing their streetscape as a digital twin with respect to physical disorder indicators. II. Compare self-report measures (Self-Assessment Manikin and state anxiety ratings) between participants viewing, in virtual reality, their streetscape as a digitally manipulated opposite version with respect to physical disorder indicators versus participants viewing their streetscape as a digital twin with respect to physical disorder indicators. III. Record side effects of interacting within a virtual reality environment over short periods of time (3-5 min): IIIa. Quantify frequency of side effects; IIIb. Explore whether side effects increase across subsequent VR sessions of the cross-over study; IIIc. Explore whether side effects vary by VR intervention arm (digital twin of own streetscape or digitally manipulated opposite indicators of physical disorder of own streetscape). IV. Analyze impact of covariates on study outcomes. EXPLORATORY OBJECTIVES: I. Compare eye gaze density between participants viewing, in virtual reality, their streetscape as a digitally manipulated opposite version with respect to physical disorder indicators versus participants viewing their streetscape as a digital twin with respect to physical disorder indicators. II. Compare self-report measures (neighborhood social cohesion and neighborhood disorder) between participants viewing, in virtual reality, their streetscape as a digitally manipulated opposite version with respect to physical disorder indicators versus participants viewing their streetscape as a digital twin with respect to physical disorder indicators. OUTLINE: Participants are randomized within their residing neighborhood to 1 of 2 arms. ARM I: Participants have their streetscape photographed. Participants view a standard residential streetscape using virtual reality (VR) for up to 5 minutes. Patients then view a digital twin of their streetscape with identical physical disorder using VR for up to 5 minutes followed by viewing their streetscape with the opposite physical disorder using VR for up to 5 minutes. ARM II: Participants have their streetscape photographed. Participants view a standard residential streetscape using VR for up to 5 minutes. Patients then view their streetscape with the opposite physical disorder using VR for up to 5 minutes followed by viewing a digital twin of their streetscape with identical physical disorder using VR for up to 5 minutes.

Arms & interventions

  • OtherSurvey Administration

    Ancillary studies

  • OtherVirtual Technology Intervention

    View standard streetscape

  • OtherVirtual Technology Intervention

    View digital twin of streetscape

  • OtherVirtual Technology Intervention

    View opposite digital streetscape

Outcome measures

Primary

  • Change in heart rate variability

    Mean heart rate variability over the entire session of each VR condition will be calculated from electrocardiograph data. Will compare the difference between two VR conditions (viewing opposite neighborhood image versus viewing twin neighborhood image) using a crossover design. Analyses of outcomes will be conducted using generalized linear mixed model approaches.

    Time frame: From baseline to completion of virtual reality (VR) viewings, up to 1 day

  • Change in skin conductance

    Skin conductance, measured as microsiemens, will be calculated as the mean value over each VR condition. Will compare the difference between two VR conditions (viewing opposite neighborhood image versus viewing twin neighborhood image) using a crossover design. Analyses of outcomes will be conducted using generalized linear mixed model approaches.

    Time frame: From baseline to completion of VR viewings, up to 1 day

  • Affective reaction

    Assessed via Self-assessment Manikin. Will compare the difference between two VR conditions (viewing opposite neighborhood image versus viewing twin neighborhood image) using a crossover design. Analyses of outcomes will be conducted using generalized linear mixed model approaches.

    Time frame: After completion of VR viewings, up to 1 day

  • Anxiety

    Assessed via Spielberger State-Trait Anxiety Inventory short form. Will compare the difference between two VR conditions (viewing opposite neighborhood image versus viewing twin neighborhood image) using a crossover design. Analyses of outcomes will be conducted using generalized linear mixed model approaches.

    Time frame: After completion of VR viewings, up to 1 day

  • Participant reported discomfort

    This is an open-ended outcome measure. Discomfort reported by participants will be recorded by study staff.

    Time frame: After completion of VR viewings, up to 1 day

Eligibility criteria

Sex: AllAge: 18 Years and olderHealthy volunteers: Yes
Inclusion Criteria: * Adults 18+ * Must currently live (4+ night/week) at the residence being studied. Only one resident per household will be selected * Must understand and be able to read English * Must agree to have residence photographed * Must be able to wear a VR head mounted display * Must live in neighborhood that has been selected for study * Must be willing and able to attend an approximately 2 hour in-person visit on Ohio State University (OSU) campus Exclusion Criteria: * Pregnant women * Visual or mobility impairment * Cannot have epilepsy or other condition that would inhibit them from being able to use a VR headset

Study locations (1)

Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210

Recruiting
Jesse Plascak, PhD, MPH · Contact
Jesse Plascak, PhD, MPH · Principal Investigator