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Patient Engagement in Using the Technology for Self-Tracking Medication Safety Events

NCT ID: NCT07291414Sponsor: University of Michigan Rogel Cancer CenterLast updated: 2026-01-21

Summary

This clinical trial evaluates the usefulness of a self-monitoring platform for tracking medication safety events and concerns in patients with lung, colorectal, breast, and prostate cancer. Patients receiving oral anticancer agents often encounter challenges in managing complex treatment regimens, potentially life-threatening toxicities, and drug-drug and drug-food interactions at home. To achieve the goal of medication safety, they need to become "vigilant partners" in medication and toxicity self-monitoring, including timely reporting of medication events to clinicians when their care transitions back home. In this study, patients use an online self-monitoring platform to track their experiences or concerns about taking their medications, including their experiences with symptoms. This platform may be a useful way for patients to track problems they have when taking their medications at home and may help them take better care of their health.

Arms & interventions

  • OtherEducational Intervention

    Receive educational materials and resources

  • OtherElectronic Health Record Review

    Ancillary studies

  • ProcedureFollow-Up

    Receive follow-up contact

  • OtherInternet-Based Intervention

    Use self-monitoring platform

  • OtherInterview

    Ancillary studies

  • OtherSurvey Administration

    Ancillary studies

Outcome measures

Primary

  • Self-reported system usability

    Self-reported system usability will be assessed using the 10-item System Usability Scale. Will use descriptive statistics, such as mean and standard deviation for continuous variables, and frequency and percentage for categorical variables.

    Time frame: Up to 6 months

  • Perceived usefulness

    Qualitative data, including brief interview data will be analyzed and summarized through content analysis.

    Time frame: Up to 6 months

  • Ease of use

    Qualitative data, including brief interview data will be analyzed and summarized through content analysis.

    Time frame: Up to 6 months

  • Attitudes toward use

    Qualitative data, including brief interview data will be analyzed and summarized through content analysis.

    Time frame: Up to 6 months

  • Intention to use and continuous use of the system over time

    Qualitative data, including brief interview data will be analyzed and summarized through content analysis.

    Time frame: Up to 12 months

  • Self-reported patient engagement

    Self-reported patient engagement will be measured by the 9-item Twente Engagement with Ehealth Technologies Scale (TWEETS), including three dimensions, behavioral engagement, cognitive engagement, and affective engagement. Will use the overall TWEETS score to evaluate patient engagement in this study, rather than analyzing each dimension separately. Will use descriptive statistics, such as mean and standard deviation for continuous variables, and frequency and percentage for categorical variables. Will use repeated measures analysis of variance to assess the changes in mean scores of patient engagement. Univariate associations between baseline personal and clinical factors and patient engagement at each time point will be assessed using correlation analyses (Pearson or Spearman), Chi-square tests, or non-parametric Mann-Whitney U tests, depending on the variable types. Multiple linear regressions will be conducted to assess associations between patient engagement and outcomes.

    Time frame: Up to 6 months

  • System usage over time

    Will be objectively recorded by the system logs and analyzed using Google Analytics (dashboard only), including parameters like the number of logins, number of tab pages clicked, number of events or concerns self-tracked, and more. Will use descriptive statistics, such as mean and standard deviation for continuous variables, and frequency and percentage for categorical variables.

    Time frame: Up to 12 months

  • Patient activation levels

    Patient activation levels will be measured by the Short Form of Patient Activation Measure. Will use descriptive statistics, such as mean and standard deviation for continuous variables, and frequency and percentage for categorical variables.

    Time frame: Up to 6 months

  • Medication self-management ability

    Medication self-management ability will be measured by the Measure of Medication Self-Management. Will use descriptive statistics, such as mean and standard deviation for continuous variables, and frequency and percentage for categorical variables.

    Time frame: Up to 6 months

  • Symptom distress

    Symptom distress will be measured by the 19-item MD Anderson Symptom Inventory. Will use descriptive statistics, such as mean and standard deviation for continuous variables, and frequency and percentage for categorical variables.

    Time frame: Up to 6 months

  • Health related quality of life

    Health-related quality of life will be measured by the 27-item Functional Assessment of Cancer Therapy - General. Will use descriptive statistics, such as mean and standard deviation for continuous variables, and frequency and percentage for categorical variables.

    Time frame: Up to 6 months

  • Number of emergency room visits

    Will be measured by both self-report and chart review. Will use descriptive statistics, such as mean and standard deviation for continuous variables, and frequency and percentage for categorical variables.

    Time frame: Up to 12 months

  • Number of hospitalizations

    Will be measured by both self-report and chart review. Will use descriptive statistics, such as mean and standard deviation for continuous variables, and frequency and percentage for categorical variables.

    Time frame: Up to 12 months

  • User experiences with the system

    Participants' user experiences with the system, such as perceived facilitators or barrios to system use, along with their suggestions for system improvement, will be collected through a brief individual interview. Qualitative data, including brief interview data will be analyzed and summarized through content analysis.

    Time frame: Up to 6 months

Secondary

  • Self-tracked, structured medication safety events or concerns

    Time frame: Up to 12 months

Eligibility criteria

Sex: AllAge: 18 Years and olderHealthy volunteers: No
Inclusion Criteria: * Participants are adult patients (aged 18 years or older) * Diagnosed with lung, colorectal, breast, or prostate cancer * Are currently receiving active cancer treatments * Are self-managing one or more prescribed cancer medications * Participants must have access to technology devices (smartphone, tablet, computer) to track their experiences or concerns about medication safety events, or their family members can help them access technology devices to track the events or concerns * Speaks and reads English or has a support person (family member or friend) who can assist Exclusion Criteria: * Can't access technology or do not use technology * Do not have access to the internet * Do not speak or read English * Not permitted to participate by their health care providers

Study locations (1)

University of Michigan Comprehensive Cancer Center

Ann Arbor, Michigan, 48109

Recruiting
Yun Jiang · Contact
Yun Jiang · Principal Investigator