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RecruitingObservational

An Investigation of Tumor Genomics, Individual Risk Factors, and External Drivers of Health to Improve Health Outcomes for Patients With Meningioma

NCT ID: NCT07418775Sponsor: University of California, San FranciscoLast updated: 2026-05-19

Summary

Meningiomas are the most common primary brain tumor, and some groups are diagnosed with higher-grade tumors and have clinically worse outcomes. This study investigates social determinants of health and individual risk factors that may be associated with meningioma.

Detailed description

PRIMARY OBJECTIVES: I. To assess prevalence and distribution of social and structural determinants of health (SSDH) among meningioma patients. II. To assess disparities in SSDH among meningioma patients of different races. OUTLINE: This is an observational study. Participants will complete a survey and have their medical records reviewed.

Arms & interventions

  • BehavioralQuestionnaire

    A questionnaire will be administered in person or online

  • OtherMedical Record Review

    Medical records will be reviewed for study specific data collection

Outcome measures

Primary

  • Identifying potential social and structural determinants of health (SSDH)

    The prevalence of SSDH factors such as race and ethnicity, birthplace, relationship status, sexual orientation/gender identity, education level, socio-economic status, access to care, reproductive/menstrual history, health factors and medication use, chemical and radiation exposure, smoking history, and perceived stress for participants with meningioma will be analyzed using multilevel logistic and linear models accounting for geographical clustering.

    Time frame: Up to 5 years

  • Distribution of social and structural determinants of health

    The distribution of SSDH factors across racial groups will be analyzed using multilevel logistic and linear models accounting for geographical clustering.

    Time frame: Up to 5 years

  • Identify disparities in social and structural determinants of health (SSDH)

    Disparities of SSDH factors across racial groups will be analyzed using multilevel logistic and linear models accounting for geographical clustering.

    Time frame: Up to 5 years

Eligibility criteria

Sex: AllAge: 18 Years and olderHealthy volunteers: Yes
Inclusion Criteria: * Adults ≥18 years of age * Able to speak and read English * Diagnosed with a meningioma Exclusion Criteria: * Active psychiatric issues (suicidality, active psychosis, grave disability, etc.) * Inability to consent secondary to severe neurologic deficit or psychiatric distress * Inability to complete survey secondary to severe neurologic deficit or psychiatric distress

Study locations (1)

University of California San Francisco

San Francisco, California, 94143

Recruiting
David Raleigh, MD PhD · Principal Investigator
Tumor Genomics, Individual Risk Factors, and External Drivers of Health on Health Outcomes for Patients With Meningioma | Cancerify