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RecruitingInterventional

Ocular Imaging for Monitoring of Ocular Tumor Disease

NCT ID: NCT07449195Sponsor: Memorial Sloan Kettering Cancer CenterLast updated: 2026-05-13

Summary

The purpose of this study is to compare two devices used for optical coherence tomography (OCT). OCT is a noninvasive imaging (scanning) method that uses reflected light to create pictures of the back of the eye, and doctors can use OCT to detect and monitor different types of cancer

Arms & interventions

  • Diagnostic TestIntalight Dream OCT

    This is a next-generation swept-source device that has a faster imaging speed and higher sensitivity than the previous generation of frequency-domain OCT devices, which serve as the current standard of care devices.

  • Diagnostic TestHeidelberg Spectralis OCT

    This is the standard of care for optical imaging.

Outcome measures

Primary

  • Image quality for participants

    Evaluated by next-generation swept-source OCT versus standard OCT for imaging of the eye and any relevant ocular tumors.

    Time frame: Up to 1 year

  • Field of view for participants

    Evaluated by next-generation swept-source OCT versus standard OCT for imaging of the eye and any relevant ocular tumors.

    Time frame: Up to 1 year

Eligibility criteria

Sex: AllAge: 18 Years and olderHealthy volunteers: No
Inclusion Criteria: * Age ≥18 years. * At least 1 eye that has an intraocular or ocular surface tumor. * The presence of a natural crystalline lens or intraocular lens. * Pupils that can dilate up to at least 3 mm in the study eyes. * The absence of opaque natural crystalline lenses or the presence of any ocular disease that prevents the view of the retina for imaging. * Patients must be able to fixate on the imaging target. * Patients must be able to sit still for a period of time (approximately 2 minutes). Exclusion Criteria: * Does not meet ALL of the above conditions

Study locations (7)

Memorial Sloan Kettering at Basking Ridge (Consent Only)

Basking Ridge, New Jersey, 07920

Recruiting
Jasmine Francis, MD · Contact

Memorial Sloan Kettering Monmouth (Consent only)

Middletown, New Jersey, 07748

Recruiting
Jasmine Francis, MD · Contact

Memorial Sloan Kettering Bergen (Consent Only)

Montvale, New Jersey, 07645

Recruiting
Jasmine Francis, MD · Contact

Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Consent only)

Commack, New York, 11725

Recruiting
Jasmine Francis, MD · Contact

Memorial Sloan Kettering Westchester (Consent Only)

Harrison, New York, 10604

Recruiting
Jasmine Francis, MD · Contact

Memorial Sloan Kettering Cancer Center (All Protocol Activites)

New York, New York, 10065

Recruiting
Jasmine Francis, MD · Contact

Memorial Sloan Kettering Cancer Center @ Nassau (Consent only)

Uniondale, New York, 11553

Recruiting
Jasmine Francis, MD · Contact
A Study Comparing Two Optical Coherence Tomography Devices in People With Ocular Tumors | Cancerify