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GET FIT Together: Testing a Socially Enhanced Exercise Program in Older Men With Prostate Cancer

NCT ID: NCT07504835Sponsor: OHSU Knight Cancer InstituteLast updated: 2026-05-06

Summary

This clinical trial tests the impact of different levels of social support on the benefits of exercise in older men with prostate cancer. This trial compares a socially-enhanced supervised group exercise program to a supervised group exercise program with no social enhancement, and an unsupervised home-based program on cancer loneliness, social isolation, mental and physical health in older prostate cancer survivors. All study arms exercise for 6 months and outcomes are measured at baseline, 3 and 6 months. The primary outcome is cancer loneliness with secondary outcomes of mental and physical health.

Detailed description

PRIMARY OBJECTIVE I. Determine the preliminary efficacy of socially-enhanced supervised group exercise on cancer loneliness and social isolation in older PCS. SECONDARY OBJECTIVE: I. Examine potential mediators of the effect of socially-enhanced supervised group exercise on cancer loneliness (social support for exercise, cancer-related negative social expectations and self-efficacy). TERTIARY OBJECTIVE: I. Determine the preliminary efficacy of socially-enhanced supervised group exercise on mental health (anxiety, depressive symptoms) and physical health (fatigue and physical function) in older PCS. OUTLINE: PCS are randomized to 1 of 3 arms. ARM I: PCS participate in online supervised group exercise training led by a certified exercise instructor over 60 minutes with additional 15-minute pre-exercise social time 3 times weekly over 6 months. ARM II: PCS participate in online supervised group exercise training led by a certified exercise instructor over 60 minutes 3 times weekly over 6 months. ARM III: PCS participate in independent exercise training following written manual and video over 60 minutes 3 times weekly over 6 months. Men have two individual training sessions with the trainer to learn the exercise program and then the trainer will check in monthly to adjust the program as necessary.

Arms & interventions

  • BehavioralSocially enhanced supervised group exercise

    Participate in online 15 minute social time prior to participating in a one hour online supervised group exercise session

  • BehavioralExercise Intervention

    Participate in a one hour online supervised group exercise session

  • BehavioralUnsupervised independent exercise

    Participate a one hour exercise session at home by following a written manual and video

Outcome measures

Primary

  • Cancer loneliness

    Assessed by the 7-item Cancer Loneliness scale measures cancer-related loneliness. Each items asks how often people experience a feeling of loneliness specific to having cancer, such as "how often do you feel others cannot provide the support your need to deal with your cancer?" on a Likert scale of 1 (never) to 5 (always). Responses are averaged and scores range from 1-7 with higher scores indicating greater feelings of cancer loneliness. The scale has excellent reliability and construct validity in adult cancer survivors.

    Time frame: Baseline, 3- and 6-months

Secondary

  • General loneliness

    Time frame: Baseline, 3- and 6-months

  • Social isolation

    Time frame: Baseline, 3- and 6-months

  • Physical health

    Time frame: Baseline, 3- and 6-months

  • Mental health

    Time frame: Baseline, 3- and 6-months

Eligibility criteria

Sex: MaleAge: 65 Years and olderHealthy volunteers: No
Inclusion Criteria: * Age 65 years of age or older. * Diagnosed with histologically confirmed prostate cancer. * Completed surgery, chemotherapy, radiation and/or systemic treatment (other than ADT) for cancer \> 3 months ago. * Experiencing cancer loneliness. * Able to ambulate independently; reliance on assistive devices other than a wheelchair is allowed. * Willing to be randomized into any of the three study arms and attend 80% or more of planned exercise sessions. * Home internet sufficient for videoconferencing. Exclusion Criteria: * Participating in regular group exercise and/or structured resistance training with other cancer survivors (\> 1 exercise partner or groups of 3 or more). * Health or medical condition that affects movement or neurological disorder, or medication that contraindicates participation in live remote resistance exercise. * Cognitive difficulties that preclude answering the survey questions, participating in the intervention, or giving informed consent. * Not fluent in English and therefore incapable of answer survey questions, following directions during exercise or performance testing, and providing informed consent in English.

Study locations (1)

OHSU Knight Cancer Institute

Portland, Oregon, 97239

Recruiting
Carolyn Guidarelli, MPH · Contact
Kerri Winters-Stone · Principal Investigator
GET FIT Together: Testing a Socially Enhanced Exercise Program in Older Men With Prostate Cancer | Cancerify