Evaluating an Anti-Cancer Drug with Immunotherapy After Kidney Cancer Surgery
NCT06661720 · RecruitingAbout this trial
This trial looks at how adding an anti-cancer drug called tivozanib to the standard treatment of pembrolizumab helps people after surgery for high-risk kidney cancer. Researchers want to see if this combination is better than using pembrolizumab alone. The goal is to help the body's immune system fight the cancer and stop tumor cells from growing and spreading.
Locations and contact
This trial is running at 415 locations in the United States. 405 of them are currently recruiting.
United States415 locations · 405 recruiting
- Abbott-Northwestern HospitalMinneapolis, MinnesotaRecruiting
- Addison Gilbert HospitalGloucester, MassachusettsRecruiting
- AdventHealth HendersonvilleHendersonville, North CarolinaRecruiting
- AdventHealth Infusion Center AshevilleAsheville, North CarolinaRecruiting
- AdventHealth Infusion Center HaywoodClyde, North CarolinaRecruiting
- AdventHealth Infusion Center WeavervilleWeaverville, North CarolinaRecruiting
- Advocate Christ Medical CenterOak Lawn, IllinoisRecruiting
- Advocate Good Samaritan HospitalDowners Grove, IllinoisRecruiting
- Advocate Good Shepherd HospitalBarrington, IllinoisRecruiting
- Advocate High Tech Medical ParkPalos Heights, IllinoisRecruiting
- Advocate Illinois Masonic Medical CenterChicago, IllinoisRecruiting
- Advocate Lutheran General HospitalPark Ridge, IllinoisRecruiting
- Advocate Outpatient Center - AuroraAurora, IllinoisRecruiting
- Advocate Outpatient Center - Oak LawnOak Lawn, IllinoisRecruiting
- Advocate Sherman HospitalElgin, IllinoisRecruiting
- Advocate South Suburban HospitalHazel Crest, IllinoisRecruiting
- AMG Crystal Lake - OncologyCrystal Lake, IllinoisRecruiting
- AMG Libertyville - OncologyLibertyville, IllinoisRecruiting
- Atrium Medical Center-Middletown Regional HospitalFranklin, OhioRecruiting
- Aultman Health FoundationCanton, OhioRecruiting
- Aurora Bay Area Medical Group-MarinetteMarinette, WisconsinRecruiting
- Aurora BayCare Medical CenterGreen Bay, WisconsinRecruiting
- Aurora Cancer Care-GraftonGrafton, WisconsinRecruiting
- Aurora Cancer Care-Kenosha SouthKenosha, WisconsinRecruiting
- Aurora Cancer Care-MilwaukeeMilwaukee, WisconsinRecruiting
- Aurora Cancer Care-Milwaukee WestWauwatosa, WisconsinRecruiting
- Aurora Cancer Care-RacineRacine, WisconsinRecruiting
- Aurora Cancer Care-Southern Lakes VLCCBurlington, WisconsinRecruiting
- Aurora Health Care Germantown Health CenterGermantown, WisconsinRecruiting
- Aurora Medical Center in SummitSummit, WisconsinRecruiting
- Aurora Saint Luke's Medical CenterMilwaukee, WisconsinRecruiting
- Aurora Saint Luke's South ShoreCudahy, WisconsinRecruiting
- Aurora Sinai Medical CenterMilwaukee, WisconsinRecruiting
- Aurora West Allis Medical CenterWest Allis, WisconsinRecruiting
- Banner University Medical Center - TucsonTucson, ArizonaRecruiting
- Baptist Cancer Center-GrenadaGrenada, MississippiRecruiting
- Baptist Health LouisvilleLouisville, KentuckyRecruiting
- Baptist Memorial Hospital and Cancer Center-ColliervilleCollierville, TennesseeRecruiting
- Baptist Memorial Hospital and Cancer Center-DesotoSouthhaven, MississippiRecruiting
- Baptist Memorial Hospital and Cancer Center-Golden TriangleColumbus, MississippiRecruiting
- Baptist Memorial Hospital and Cancer Center-MemphisMemphis, TennesseeRecruiting
- Baptist Memorial Hospital and Cancer Center-OxfordOxford, MississippiRecruiting
- Baptist Memorial Hospital and Cancer Center-Union CountyNew Albany, MississippiRecruiting
- Beebe Health CampusRehoboth Beach, DelawareRecruiting
- Beebe South Coastal Health CampusMillville, DelawareRecruiting
- Benefis Sletten Cancer InstituteGreat Falls, MontanaRecruiting
- Beverly HospitalBeverly, MassachusettsRecruiting
- Billings Clinic Cancer CenterBillings, MontanaRecruiting
- BJC Outpatient Center at Sunset HillsSunset Hills, MissouriRecruiting
- Bon Secours Memorial Regional Medical CenterMechanicsville, VirginiaRecruiting
- Bon Secours Richmond Community HospitalRichmond, VirginiaRecruiting
- Bon Secours Saint Francis Medical CenterMidlothian, VirginiaRecruiting
- Bon Secours Saint Mary's HospitalRichmond, VirginiaRecruiting
- Bozeman Health Deaconess HospitalBozeman, MontanaRecruiting
- Bronson Battle CreekBattle Creek, MichiganRecruiting
- Bronson Methodist HospitalKalamazoo, MichiganRecruiting
- California Pacific Medical Center-Pacific CampusSan Francisco, CaliforniaRecruiting
- Camden Clark Medical CenterParkersburg, West VirginiaRecruiting
- Cancer and Hematology Centers of Western Michigan - Norton ShoresNorton Shores, MichiganRecruiting
- Cancer Care and Hematology-Fort CollinsFort Collins, ColoradoRecruiting
- Cancer Care Center of O'FallonO'Fallon, IllinoisRecruiting
- Cancer Care Specialists of Illinois - DecaturDecatur, IllinoisRecruiting
- Cancer Center at Saint Joseph'sPhoenix, ArizonaRecruiting
- Cancer Center of Western WisconsinNew Richmond, WisconsinRecruiting
- Cancer Centers of Southwest Oklahoma ResearchLawton, OklahomaRecruiting
- Cancer Hematology Centers - FlintFlint, MichiganRecruiting
- Carle at The RiverfrontDanville, IllinoisRecruiting
- Carle Cancer CenterUrbana, IllinoisRecruiting
- Carle Physician Group-EffinghamEffingham, IllinoisRecruiting
- Carle Physician Group-Mattoon/CharlestonMattoon, IllinoisRecruiting
- Case Western Reserve UniversityCleveland, OhioRecruiting
- Cedars-Sinai Medical CenterLos Angeles, CaliforniaRecruiting
- Central Vermont Medical Center/National Life Cancer TreatmentBerlin Corners, VermontRecruiting
- City of Hope Antelope ValleyLancaster, CaliforniaRecruiting
- City of Hope at Irvine LennarIrvine, CaliforniaRecruiting
- City of Hope Comprehensive Cancer CenterDuarte, CaliforniaRecruiting
- City of Hope South BayTorrance, CaliforniaRecruiting
- City of Hope UplandUpland, CaliforniaRecruiting
- Coborn Cancer Center at Saint Cloud HospitalSaint Cloud, MinnesotaRecruiting
- Community Hospital of AnacondaAnaconda, MontanaRecruiting
- Community Medical CenterMissoula, MontanaRecruiting
- Community Medical CenterScranton, PennsylvaniaRecruiting
- Condell Memorial HospitalLibertyville, IllinoisRecruiting
- Corewell Health Grand Rapids Hospitals - Butterworth HospitalGrand Rapids, MichiganRecruiting
- Corewell Health Lakeland Hospitals - Marie Yeager Cancer CenterSaint Joseph, MichiganRecruiting
- Corewell Health Lakeland Hospitals - Niles HospitalNiles, MichiganRecruiting
- Corewell Health Lakeland Hospitals - Saint Joseph HospitalSaint Joseph, MichiganRecruiting
- Corewell Health Reed City HospitalReed City, MichiganRecruiting
- Crossroads Cancer CenterEffingham, IllinoisRecruiting
- Dana Farber-Merrimack ValleyMethuen, MassachusettsRecruiting
- Dana-Farber Cancer InstituteBoston, MassachusettsRecruiting
- Dana-Farber Cancer Institute at FoxboroughFoxborough, MassachusettsRecruiting
- Dana-Farber/Brigham and Women's Cancer Center at Milford RegionalMilford, MassachusettsRecruiting
- Dana-Farber/Brigham and Women's Cancer Center at South ShoreSouth Weymouth, MassachusettsRecruiting
- Dartmouth Hitchcock Medical Center/Dartmouth Cancer CenterLebanon, New HampshireRecruiting
- Decatur Memorial HospitalDecatur, IllinoisRecruiting
- Divine Providence HospitalWilliamsport, PennsylvaniaRecruiting
- Drexel Town Square Health CenterOak Creek, WisconsinRecruiting
- Duke Cancer Center CaryCary, North CarolinaRecruiting
- Duke Cancer Center RaleighRaleigh, North CarolinaRecruiting
- Duke Cancer Center SouthpointDurham, North CarolinaRecruiting
- Duke University Medical CenterDurham, North CarolinaRecruiting
- Duluth Clinic AshlandAshland, WisconsinRecruiting
- Edward Hospital/Cancer CenterNaperville, IllinoisRecruiting
- Edward Hospital/Cancer Center?PlainfieldPlainfield, IllinoisRecruiting
- Elmhurst Memorial HospitalElmhurst, IllinoisRecruiting
- Emory Johns Creek HospitalJohns Creek, GeorgiaRecruiting
- Emory Saint Joseph's HospitalAtlanta, GeorgiaRecruiting
- Emory University Hospital MidtownAtlanta, GeorgiaRecruiting
- Emory University Hospital/Winship Cancer InstituteAtlanta, GeorgiaRecruiting
- Essentia Health - Deer River ClinicDeer River, MinnesotaRecruiting
- Essentia Health Cancer CenterDuluth, MinnesotaRecruiting
- Essentia Health Cancer Center-South University ClinicFargo, North DakotaRecruiting
- Essentia Health Hibbing ClinicHibbing, MinnesotaRecruiting
- Essentia Health Saint Joseph's Medical CenterBrainerd, MinnesotaRecruiting
- Essentia Health SandstoneSandstone, MinnesotaRecruiting
- Essentia Health Virginia ClinicVirginia, MinnesotaRecruiting
- Fairview Southdale HospitalEdina, MinnesotaRecruiting
- FirstHealth of the Carolinas-Moore Regional HospitalPinehurst, North CarolinaRecruiting
- Froedtert Menomonee Falls HospitalMenomonee Falls, WisconsinRecruiting
- Froedtert West Bend Hospital/Kraemer Cancer CenterWest Bend, WisconsinRecruiting
- Geisinger Cancer Center Dickson CityDickson City, PennsylvaniaRecruiting
- Geisinger Medical CenterDanville, PennsylvaniaRecruiting
- Geisinger Medical Center-Cancer Center HazletonHazleton, PennsylvaniaRecruiting
- Geisinger Medical Oncology-LewisburgLewisburg, PennsylvaniaRecruiting
- Geisinger Wyoming Valley/Henry Cancer CenterWilkes-Barre, PennsylvaniaRecruiting
- Genesys Hurley Cancer InstituteFlint, MichiganRecruiting
- George Washington University Medical CenterWashington D.C., District of ColumbiaRecruiting
- Gibbs Cancer Center-GaffneyGaffney, South CarolinaRecruiting
- Gibbs Cancer Center-PelhamGreer, South CarolinaRecruiting
- Glens Falls HospitalGlens Falls, New YorkRecruiting
- Grady Health SystemAtlanta, GeorgiaRecruiting
- Gundersen Lutheran Medical CenterLa Crosse, WisconsinRecruiting
- Hackensack University Medical CenterHackensack, New JerseyRecruiting
- Hartford HealthCare - AvonAvon, ConnecticutRecruiting
- Hartford Healthcare - FairfieldFairfield, ConnecticutRecruiting
- Hartford HealthCare - ManchesterManchester, ConnecticutRecruiting
- Hartford HealthCare - Saint Vincent's Medical CenterBridgeport, ConnecticutRecruiting
- Hartford HospitalHartford, ConnecticutRecruiting
- Helen F Graham Cancer CenterNewark, DelawareRecruiting
- Hematology Oncology Associates of Central New York-East SyracuseEast Syracuse, New YorkRecruiting
- Hematology Oncology Associates of CNY at CamillusCamillus, New YorkRecruiting
- Hennepin County Medical CenterMinneapolis, MinnesotaRecruiting
- Houston Methodist Cypress HospitalCypress, TexasRecruiting
- Houston Methodist HospitalHouston, TexasRecruiting
- Houston Methodist Saint John HospitalNassau Bay, TexasRecruiting
- Houston Methodist San Jacinto HospitalBaytown, TexasRecruiting
- Houston Methodist Sugar Land HospitalSugar Land, TexasRecruiting
- Houston Methodist The Woodlands HospitalThe Woodlands, TexasRecruiting
- Houston Methodist West HospitalHouston, TexasRecruiting
- Illinois CancerCare - WashingtonWashington, IllinoisRecruiting
- Illinois CancerCare-BloomingtonBloomington, IllinoisRecruiting
- Illinois CancerCare-CantonCanton, IllinoisRecruiting
- Illinois CancerCare-CarthageCarthage, IllinoisRecruiting
- Illinois CancerCare-DixonDixon, IllinoisRecruiting
- Illinois CancerCare-EurekaEureka, IllinoisRecruiting
- Illinois CancerCare-GalesburgGalesburg, IllinoisRecruiting
- Illinois CancerCare-Kewanee ClinicKewanee, IllinoisRecruiting
- Illinois CancerCare-MacombMacomb, IllinoisRecruiting
- Illinois CancerCare-Ottawa ClinicOttawa, IllinoisRecruiting
- Illinois CancerCare-PekinPekin, IllinoisRecruiting
- Illinois CancerCare-PeoriaPeoria, IllinoisRecruiting
- Illinois CancerCare-PeruPeru, IllinoisRecruiting
- Illinois CancerCare-PrincetonPrinceton, IllinoisRecruiting
- Indiana University/Melvin and Bren Simon Cancer CenterIndianapolis, IndianaRecruiting
- IU Health North HospitalCarmel, IndianaRecruiting
- IU Health West HospitalAvon, IndianaRecruiting
- Jefferson Cherry Hill HospitalCherry Hill, New JerseyRecruiting
- Jefferson Torresdale HospitalPhiladelphia, PennsylvaniaRecruiting
- Kettering Medical CenterKettering, OhioRecruiting
- Kootenai Clinic Cancer Services - Post FallsPost Falls, IdahoRecruiting
- Kootenai Clinic Cancer Services - SandpointSandpoint, IdahoRecruiting
- Kootenai Health - Coeur d'AleneCoeur d'Alene, IdahoRecruiting
- Lafayette Family Cancer Center-EMMCBrewer, MaineRecruiting
- Lahey ClinicBurlington, MassachusettsRecruiting
- Lahey Clinic PeabodyPeabody, MassachusettsRecruiting
- Lehigh Valley Hospital - MuhlenbergBethlehem, PennsylvaniaRecruiting
- Lehigh Valley Hospital-Cedar CrestAllentown, PennsylvaniaRecruiting
- Lehigh Valley Hospital-HazletonHazleton, PennsylvaniaRecruiting
- Lenox Hill HospitalNew York, New YorkRecruiting
- Logan Health Medical CenterKalispell, MontanaRecruiting
- Los Angeles General Medical CenterLos Angeles, CaliforniaRecruiting
- Manhattan Eye Ear and Throat HospitalNew York, New YorkRecruiting
- Mary Greeley Medical CenterAmes, IowaRecruiting
- McFarland Clinic - AmesAmes, IowaRecruiting
- McFarland Clinic - MarshalltownMarshalltown, IowaRecruiting
- McFarland Clinic - Trinity Cancer CenterFort Dodge, IowaRecruiting
- Medical Center of the RockiesLoveland, ColoradoRecruiting
- Medical College of WisconsinMilwaukee, WisconsinRecruiting
- Medical Oncology Hematology Consultants PANewark, DelawareRecruiting
- Medical University of South CarolinaCharleston, South CarolinaRecruiting
- MedStar Washington Hospital CenterWashington D.C., District of ColumbiaRecruiting
- Memorial Hospital EastShiloh, IllinoisRecruiting
- Memorial Hospital NorthColorado Springs, ColoradoRecruiting
- Memorial Medical CenterModesto, CaliforniaRecruiting
- Memorial Sloan Kettering Basking RidgeBasking Ridge, New JerseyRecruiting
- Memorial Sloan Kettering BergenMontvale, New JerseyRecruiting
- Memorial Sloan Kettering Cancer CenterNew York, New YorkRecruiting
- Memorial Sloan Kettering CommackCommack, New YorkRecruiting
- Memorial Sloan Kettering MonmouthMiddletown, New JerseyRecruiting
- Memorial Sloan Kettering NassauUniondale, New YorkRecruiting
- Memorial Sloan Kettering WestchesterHarrison, New YorkRecruiting
- Mercy HospitalCedar Rapids, IowaRecruiting
- Mercy HospitalCoon Rapids, MinnesotaRecruiting
- Mercy Hospital Saint LouisSt Louis, MissouriRecruiting
- Mercy Hospital SouthSt Louis, MissouriRecruiting
- Methodist Willowbrook HospitalHouston, TexasRecruiting
- Miami Cancer InstituteMiami, FloridaRecruiting
- Miami Valley Cancer Care and InfusionGreenville, OhioRecruiting
- Miami Valley HospitalDayton, OhioRecruiting
- Miami Valley Hospital NorthDayton, OhioRecruiting
- Miami Valley Hospital SouthCenterville, OhioRecruiting
- Midstate Medical CenterMeriden, ConnecticutRecruiting
- Mills Health CenterSan Mateo, CaliforniaRecruiting
- Minneapolis VA Medical CenterMinneapolis, MinnesotaRecruiting
- Minnesota Oncology - BurnsvilleBurnsville, MinnesotaRecruiting
- Minnesota Oncology Hematology PA-MaplewoodMaplewood, MinnesotaRecruiting
- Minnesota Oncology Hematology PA-WoodburyWoodbury, MinnesotaRecruiting
- Missouri Baptist Medical CenterSt Louis, MissouriRecruiting
- Missouri Baptist Sullivan HospitalSullivan, MissouriRecruiting
- Monmouth Medical CenterLong Branch, New JerseyRecruiting
- Montefiore Medical Center-Einstein CampusThe Bronx, New YorkRecruiting
- Morristown Medical CenterMorristown, New JerseyRecruiting
- Mount Sinai ChelseaNew York, New YorkRecruiting
- Mount Sinai HospitalNew York, New YorkRecruiting
- Munson Medical CenterTraverse City, MichiganRecruiting
- NEA Baptist Memorial Hospital and Fowler Family Cancer Center - JonesboroJonesboro, ArkansasRecruiting
- North Memorial Medical Health CenterRobbinsdale, MinnesotaRecruiting
- Northwell Health/Center for Advanced MedicineLake Success, New YorkRecruiting
- Northwestern Medicine Cancer Center DelnorGeneva, IllinoisRecruiting
- Northwestern Medicine Cancer Center KishwaukeeDeKalb, IllinoisRecruiting
- Northwestern Medicine Cancer Center WarrenvilleWarrenville, IllinoisRecruiting
- Northwestern Medicine Glenview Outpatient CenterGlenview, IllinoisRecruiting
- Northwestern Medicine Grayslake Outpatient CenterGrayslake, IllinoisRecruiting
- Northwestern Medicine Lake Forest HospitalLake Forest, IllinoisRecruiting
- Northwestern Medicine Oak BrookOak Brook, IllinoisRecruiting
- Northwestern Medicine Orland ParkOrland Park, IllinoisRecruiting
- Northwestern UniversityChicago, IllinoisRecruiting
- Ochsner Medical Center JeffersonNew Orleans, LouisianaRecruiting
- Ohio State University Comprehensive Cancer CenterColumbus, OhioRecruiting
- Oncology Associates at Mercy Medical CenterCedar Rapids, IowaRecruiting
- Oregon Health and Science UniversityPortland, OregonRecruiting
- OSF Saint Francis Hospital and Medical GroupEscanaba, MichiganRecruiting
- Overlook HospitalSummit, New JerseyRecruiting
- Palo Alto Medical Foundation Health CarePalo Alto, CaliforniaRecruiting
- Palo Alto Medical Foundation-Santa CruzSanta Cruz, CaliforniaRecruiting
- Palo Alto Medical Foundation-SunnyvaleSunnyvale, CaliforniaRecruiting
- Park Nicollet Clinic - Saint Louis ParkSaint Louis Park, MinnesotaRecruiting
- Parkland Health Center - FarmingtonFarmington, MissouriRecruiting
- Parkland Memorial HospitalDallas, TexasRecruiting
- Pocono Medical CenterEast Stroudsburg, PennsylvaniaRecruiting
- Poudre Valley HospitalFort Collins, ColoradoRecruiting
- Prisma Health Cancer Institute - ButternutGreenville, South CarolinaRecruiting
- Prisma Health Cancer Institute - EasleyEasley, South CarolinaRecruiting
- Prisma Health Cancer Institute - EastsideGreenville, South CarolinaRecruiting
- Prisma Health Cancer Institute - FarisGreenville, South CarolinaRecruiting
- Prisma Health Cancer Institute - GreerGreer, South CarolinaRecruiting
- Prisma Health Cancer Institute - SenecaSeneca, South CarolinaRecruiting
- Prisma Health Cancer Institute - SpartanburgBoiling Springs, South CarolinaRecruiting
- ProHealth D N Greenwald CenterMukwonago, WisconsinRecruiting
- ProHealth Oconomowoc Memorial HospitalOconomowoc, WisconsinRecruiting
- ProHealth Waukesha Memorial HospitalWaukesha, WisconsinRecruiting
- Providence Newberg Medical CenterNewberg, OregonRecruiting
- Providence Portland Medical CenterPortland, OregonRecruiting
- Providence Saint Vincent Medical CenterPortland, OregonRecruiting
- Providence Willamette Falls Medical CenterOregon City, OregonRecruiting
- Regions HospitalSaint Paul, MinnesotaRecruiting
- Robert Wood Johnson University Hospital SomersetSomerville, New JerseyRecruiting
- Roswell Park Cancer InstituteBuffalo, New YorkRecruiting
- Rush MD Anderson Cancer CenterChicago, IllinoisRecruiting
- Rutgers Cancer Institute of New JerseyNew Brunswick, New JerseyRecruiting
- Rutgers New Jersey Medical SchoolNewark, New JerseyRecruiting
- Saint Francis Medical CenterCape Girardeau, MissouriRecruiting
- Saint Francis Regional Medical CenterShakopee, MinnesotaRecruiting
- Saint Luke's Cancer Institute - BoiseBoise, IdahoRecruiting
- Saint Luke's Cancer Institute - FruitlandFruitland, IdahoRecruiting
- Saint Luke's Cancer Institute - MeridianMeridian, IdahoRecruiting
- Saint Luke's Cancer Institute - NampaNampa, IdahoRecruiting
- Saint Vincent Hospital Cancer Center at Oconto FallsOconto Falls, WisconsinRecruiting
- Saint Vincent Hospital Cancer Center at Saint Mary'sGreen Bay, WisconsinRecruiting
- Saint Vincent Hospital Cancer Center at SheboyganSheboygan, WisconsinRecruiting
- Saint Vincent Hospital Cancer Center at Sturgeon BaySturgeon Bay, WisconsinRecruiting
- Saint Vincent Hospital Cancer Center Green BayGreen Bay, WisconsinRecruiting
- Sainte Genevieve County Memorial HospitalSainte Genevieve, MissouriRecruiting
- Sanford Bismarck Medical CenterBismarck, North DakotaRecruiting
- Sanford Broadway Medical CenterFargo, North DakotaRecruiting
- Sanford Cancer Center Oncology ClinicSioux Falls, South DakotaRecruiting
- Sanford Joe Lueken Cancer CenterBemidji, MinnesotaRecruiting
- Sanford Roger Maris Cancer CenterFargo, North DakotaRecruiting
- Sanford USD Medical Center - Sioux FallsSioux Falls, South DakotaRecruiting
- Scott and White Memorial HospitalTemple, TexasRecruiting
- Sheboygan Physicians GroupSheboygan, WisconsinRecruiting
- Sidney and Lois Eskenazi HospitalIndianapolis, IndianaRecruiting
- Sidney Kimmel Cancer Center Washington TownshipSewell, New JerseyRecruiting
- SIH Cancer InstituteCarterville, IllinoisRecruiting
- Siteman Cancer Center at Christian HospitalSt Louis, MissouriRecruiting
- Siteman Cancer Center at Saint Peters HospitalCity of Saint Peters, MissouriRecruiting
- Siteman Cancer Center at West County HospitalCreve Coeur, MissouriRecruiting
- Siteman Cancer Center-South CountySt Louis, MissouriRecruiting
- SMC Center for Hematology Oncology UnionUnion, South CarolinaRecruiting
- Smilow Cancer Hospital Care Center - GuilfordGuilford, ConnecticutRecruiting
- Smilow Cancer Hospital Care Center - WaterfordWaterford, ConnecticutRecruiting
- Smilow Cancer Hospital Care Center - WesterlyWesterly, Rhode IslandRecruiting
- Smilow Cancer Hospital Care Center at GreenwichGreenwich, ConnecticutRecruiting
- Smilow Cancer Hospital Care Center at Long RidgeStamford, ConnecticutRecruiting
- Smilow Cancer Hospital Care Center-FairfieldFairfield, ConnecticutRecruiting
- Smilow Cancer Hospital Care Center-TrumbullTrumbull, ConnecticutRecruiting
- Smilow Cancer Hospital-Derby Care CenterDerby, ConnecticutRecruiting
- Smilow Cancer Hospital-Torrington Care CenterTorrington, ConnecticutRecruiting
- Smilow Cancer Hospital-Waterbury Care CenterWaterbury, ConnecticutRecruiting
- Southern Illinois University School of MedicineSpringfield, IllinoisRecruiting
- Spartanburg Medical CenterSpartanburg, South CarolinaRecruiting
- Springfield ClinicSpringfield, IllinoisRecruiting
- Springfield Memorial HospitalSpringfield, IllinoisRecruiting
- Stamford Hospital/Bennett Cancer CenterStamford, ConnecticutRecruiting
- Sutter Auburn Faith HospitalAuburn, CaliforniaRecruiting
- Sutter Medical Center SacramentoSacramento, CaliforniaRecruiting
- Sutter Roseville Medical CenterRoseville, CaliforniaRecruiting
- Sutter Solano Medical Center/Cancer CenterVallejo, CaliforniaRecruiting
- The Cancer Institute of New Jersey HamiltonHamilton, New JerseyRecruiting
- The Don and Sybil Harrington Cancer CenterAmarillo, TexasRecruiting
- The Hospital of Central ConnecticutNew Britain, ConnecticutRecruiting
- The James Graham Brown Cancer Center at University of LouisvilleLouisville, KentuckyRecruiting
- ThedaCare Regional Cancer CenterAppleton, WisconsinRecruiting
- Thomas Jefferson University HospitalPhiladelphia, PennsylvaniaRecruiting
- Tidelands Georgetown Memorial HospitalGeorgetown, South CarolinaRecruiting
- Torrance Memorial Physician Network - Cancer CareTorrance, CaliforniaRecruiting
- Tower Cancer Research FoundationBeverly Hills, CaliforniaRecruiting
- Trinity Health Grand Rapids HospitalGrand Rapids, MichiganRecruiting
- Trinity Health IHA Medical Group Hematology Oncology - BrightonBrighton, MichiganRecruiting
- Trinity Health IHA Medical Group Hematology Oncology - CantonCanton, MichiganRecruiting
- Trinity Health IHA Medical Group Hematology Oncology - Chelsea HospitalChelsea, MichiganRecruiting
- Trinity Health IHA Medical Group Hematology Oncology Ann Arbor CampusYpsilanti, MichiganRecruiting
- Trinity Health Muskegon HospitalMuskegon, MichiganRecruiting
- Trinity Health Saint Joseph Mercy Oakland HospitalPontiac, MichiganRecruiting
- Trinity Health Saint Mary Mercy Livonia HospitalLivonia, MichiganRecruiting
- Trinity Medical CenterMoline, IllinoisRecruiting
- UC Irvine Health/Chao Family Comprehensive Cancer CenterOrange, CaliforniaRecruiting
- UC San Diego Medical Center - HillcrestSan Diego, CaliforniaRecruiting
- UC San Diego Moores Cancer CenterLa Jolla, CaliforniaRecruiting
- UCHealth - Cherry CreekDenver, ColoradoRecruiting
- UCHealth Greeley HospitalGreeley, ColoradoRecruiting
- UCHealth Highlands Ranch HospitalHighlands Ranch, ColoradoRecruiting
- UCHealth Lone Tree Health CenterLone Tree, ColoradoRecruiting
- UCHealth Memorial Hospital CentralColorado Springs, ColoradoRecruiting
- UCHealth University of Colorado HospitalAurora, ColoradoRecruiting
- UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory CareIrvine, CaliforniaRecruiting
- UF Health Cancer Institute - GainesvilleGainesville, FloridaRecruiting
- UH Seidman Cancer Center at Lake Health Mentor CampusMentor, OhioRecruiting
- UH Seidman Cancer Center at UH Avon Health CenterAvon, OhioRecruiting
- UHHS-Chagrin Highlands Medical CenterBeachwood, OhioRecruiting
- UNC Lineberger Comprehensive Cancer CenterChapel Hill, North CarolinaRecruiting
- United HospitalSaint Paul, MinnesotaRecruiting
- United Hospital CenterBridgeport, West VirginiaRecruiting
- University of Arizona Cancer Center-North CampusTucson, ArizonaRecruiting
- University of Arkansas for Medical SciencesLittle Rock, ArkansasRecruiting
- University of California Davis Comprehensive Cancer CenterSacramento, CaliforniaRecruiting
- University of IllinoisChicago, IllinoisRecruiting
- University of Iowa Healthcare Cancer Services Quad CitiesBettendorf, IowaRecruiting
- University of Iowa/Holden Comprehensive Cancer CenterIowa City, IowaRecruiting
- University of Michigan Health - Sparrow LansingLansing, MichiganRecruiting
- University of Michigan Health - WestWyoming, MichiganRecruiting
- University of Mississippi Medical CenterJackson, MississippiRecruiting
- University of New Mexico Cancer CenterAlbuquerque, New MexicoRecruiting
- University of Oklahoma Health Sciences CenterOklahoma City, OklahomaRecruiting
- University of Pittsburgh Cancer Institute (UPCI)Pittsburgh, PennsylvaniaRecruiting
- University of Vermont and State Agricultural CollegeBurlington, VermontRecruiting
- University of Vermont Medical CenterBurlington, VermontRecruiting
- University of Wisconsin Carbone Cancer Center - Eastpark Medical CenterMadison, WisconsinRecruiting
- University of Wisconsin Carbone Cancer Center - University HospitalMadison, WisconsinRecruiting
- UofL Health Medical Center NortheastLouisville, KentuckyRecruiting
- UPMC Cancer Center-UniontownUniontown, PennsylvaniaRecruiting
- UPMC Cancer Centers - Arnold Palmer PavilionGreensburg, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center - MonroevilleMonroeville, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center at Butler Health SystemButler, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer PavilionMechanicsburg, PennsylvaniaRecruiting
- UPMC Hillman Cancer Center ErieErie, PennsylvaniaRecruiting
- UPMC Pinnacle Cancer Center/Community Osteopathic CampusHarrisburg, PennsylvaniaRecruiting
- UPMC Western MarylandCumberland, MarylandRecruiting
- UPMC-Heritage Valley Health System BeaverBeaver, PennsylvaniaRecruiting
- UPMC-Johnstown/John P. Murtha Regional Cancer CenterJohnstown, PennsylvaniaRecruiting
- UPMC-Passavant HospitalPittsburgh, PennsylvaniaRecruiting
- UPMC-Saint Clair Hospital Cancer CenterPittsburgh, PennsylvaniaRecruiting
- Upper Valley Medical CenterTroy, OhioRecruiting
- USC / Norris Comprehensive Cancer CenterLos Angeles, CaliforniaRecruiting
- USC Norris Oncology/Hematology-Newport BeachNewport Beach, CaliforniaRecruiting
- UT Southwestern Clinical Center at Richardson/PlanoRichardson, TexasRecruiting
- UT Southwestern Simmons Cancer Center - RedBirdDallas, TexasRecruiting
- UT Southwestern/Simmons Cancer Center-DallasDallas, TexasRecruiting
- UT Southwestern/Simmons Cancer Center-Fort WorthFort Worth, TexasRecruiting
- UW Cancer Center at ProHealth CareWaukesha, WisconsinRecruiting
- Vanderbilt University/Ingram Cancer CenterNashville, TennesseeRecruiting
- VCU Community Memorial Health CenterSouth Hill, VirginiaRecruiting
- VCU Massey Cancer Center at Stony PointRichmond, VirginiaRecruiting
- VCU Massey Comprehensive Cancer CenterRichmond, VirginiaRecruiting
- Vince Lombardi Cancer Clinic - OshkoshOshkosh, WisconsinRecruiting
- Vince Lombardi Cancer Clinic-SheboyganSheboygan, WisconsinRecruiting
- Vince Lombardi Cancer Clinic-Two RiversTwo Rivers, WisconsinRecruiting
- Virginia Cancer InstituteRichmond, VirginiaRecruiting
- Washington University School of MedicineSt Louis, MissouriRecruiting
- West Michigan Cancer CenterKalamazoo, MichiganRecruiting
- West Virginia University Charleston DivisionCharleston, West VirginiaRecruiting
- West Virginia University HealthcareMorgantown, West VirginiaRecruiting
- WVUH-Berkely Medical CenterMartinsburg, West VirginiaRecruiting
- Yale UniversityNew Haven, ConnecticutRecruiting
- Dartmouth Cancer Center - NorthSaint Johnsbury, VermontSuspended
- Genesee Hematology Oncology PCFlint, MichiganSuspended
- Indu and Raj Soin Medical CenterBeavercreek, OhioSuspended
- McFarland Clinic - BooneBoone, IowaSuspended
- McFarland Clinic - JeffersonJefferson, IowaSuspended
- Rush-Copley Healthcare CenterYorkville, IllinoisSuspended
- Rush-Copley Medical CenterAurora, IllinoisSuspended
- Smilow Cancer Hospital Care Center at GlastonburyGlastonbury, ConnecticutSuspended
- Smilow Cancer Hospital Care Center at Saint FrancisHartford, ConnecticutSuspended
- Yale-New Haven Hospital North Haven Medical CenterNorth Haven, ConnecticutSuspended
Who to ask about joining
Aishwarya Vijendran773-702-9171guprotocols@alliancenctn.org
Who can join
Adults aged 18 and older can join this study. It is open to both men and women who have a specific type of kidney cancer that has been surgically removed. People with certain health conditions or those who are pregnant or nursing cannot participate. The trial team will check to see if you qualify.
What happens during the trial
Participants are randomly placed into one of two groups. In the first group, patients receive pembrolizumab through an IV. In the second group, patients receive both pembrolizumab and tivozanib, with tivozanib taken as a pill. Everyone will have regular check-ups and may have blood tests and imaging to monitor their health throughout the trial.
The trial team
The trial is sponsored by the Alliance for Clinical Trials in Oncology, which is responsible for running the study.
Important dates
The trial started on March 14, 2025, and is expected to finish around November 2037. It is currently recruiting new participants.
Additional information
The trial's ID is NCT06661720. This is a Phase 3 trial, which means researchers are studying how well the treatments work and how safe they are. About 1,040 people are expected to take part in this study. This trial does not involve FDA-regulated drugs or devices.
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