Evaluating New Drug Combinations for Early Hodgkin Lymphoma Treatment

NCT05675410 · Recruiting

About this trial

This study looks at how well two drugs, brentuximab vedotin and nivolumab, work when added to standard treatment for early Hodgkin lymphoma. The goal is to see if this combination helps improve outcomes compared to standard chemotherapy alone. The trial focuses on patients with early-stage classic Hodgkin lymphoma, which is a type of cancer that affects the lymphatic system, a part of the immune system.

Locations and contact

This trial is running at 405 locations in 3 countries. 395 of them are currently recruiting.

United States390 locations · 380 recruiting

Abbott-Northwestern HospitalMinneapolis, MinnesotaRecruiting
AdventHealth OrlandoOrlando, FloridaRecruiting
Advocate Children's Hospital-Oak LawnOak Lawn, IllinoisRecruiting
Advocate Children's Hospital-Park RidgePark Ridge, IllinoisRecruiting
Advocate Christ Medical CenterOak Lawn, IllinoisRecruiting
Advocate Good Samaritan HospitalDowners Grove, IllinoisRecruiting
Advocate Good Shepherd HospitalBarrington, IllinoisRecruiting
Advocate Illinois Masonic Medical CenterChicago, IllinoisRecruiting
Advocate Lutheran General HospitalPark Ridge, IllinoisRecruiting
Advocate Sherman HospitalElgin, IllinoisRecruiting
Advocate South Suburban HospitalHazel Crest, IllinoisRecruiting
Albany Medical CenterAlbany, New YorkRecruiting
Alfred I duPont Hospital for ChildrenWilmington, DelawareRecruiting
Allegiance HealthJackson, MichiganRecruiting
Alliance for Childhood Diseases/Cure 4 the Kids FoundationLas Vegas, NevadaRecruiting
AMG Crystal Lake - OncologyCrystal Lake, IllinoisRecruiting
AMG Libertyville - OncologyLibertyville, IllinoisRecruiting
Arkansas Children's HospitalLittle Rock, ArkansasRecruiting
Arnold Palmer Hospital for ChildrenOrlando, FloridaRecruiting
Ascension Saint Vincent Indianapolis HospitalIndianapolis, IndianaRecruiting
Atrium Health NavicentMacon, GeorgiaRecruiting
Augusta University Medical CenterAugusta, GeorgiaRecruiting
Aurora Bay Area Medical Group-MarinetteMarinette, WisconsinRecruiting
Aurora BayCare Medical CenterGreen Bay, WisconsinRecruiting
Aurora Cancer Care-GraftonGrafton, WisconsinRecruiting
Aurora Cancer Care-Kenosha SouthKenosha, WisconsinRecruiting
Aurora Cancer Care-MilwaukeeMilwaukee, WisconsinRecruiting
Aurora Cancer Care-Milwaukee WestWauwatosa, WisconsinRecruiting
Aurora Cancer Care-RacineRacine, WisconsinRecruiting
Aurora Cancer Care-Southern Lakes VLCCBurlington, WisconsinRecruiting
Aurora Health Care Germantown Health CenterGermantown, WisconsinRecruiting
Aurora Medical Center in SummitSummit, WisconsinRecruiting
Aurora Saint Luke's Medical CenterMilwaukee, WisconsinRecruiting
Aurora Saint Luke's South ShoreCudahy, WisconsinRecruiting
Aurora Sinai Medical CenterMilwaukee, WisconsinRecruiting
Aurora West Allis Medical CenterWest Allis, WisconsinRecruiting
Banner Children's at DesertMesa, ArizonaRecruiting
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer CenterHouston, TexasRecruiting
Beacon Kalamazoo Cancer CenterKalamazoo, MichiganRecruiting
BI-LO Charities Children's Cancer CenterGreenville, South CarolinaRecruiting
Blank Children's HospitalDes Moines, IowaRecruiting
Bronson Battle CreekBattle Creek, MichiganRecruiting
Bronson Methodist HospitalKalamazoo, MichiganRecruiting
Broward Health Medical CenterFort Lauderdale, FloridaRecruiting
C S Mott Children's HospitalAnn Arbor, MichiganRecruiting
Cancer and Hematology Centers of Western Michigan - Norton ShoresNorton Shores, MichiganRecruiting
Cancer Care and Hematology-Fort CollinsFort Collins, ColoradoRecruiting
Cardinal Glennon Children's Medical CenterSt Louis, MissouriRecruiting
Carilion Children'sRoanoke, VirginiaRecruiting
Carle at The RiverfrontDanville, IllinoisRecruiting
Carle Cancer CenterUrbana, IllinoisRecruiting
Carle Physician Group-EffinghamEffingham, IllinoisRecruiting
Carle Physician Group-Mattoon/CharlestonMattoon, IllinoisRecruiting
Carolinas Medical Center/Levine Cancer InstituteCharlotte, North CarolinaRecruiting
Cedars-Sinai Medical CenterLos Angeles, CaliforniaRecruiting
Children's Healthcare of Atlanta - Arthur M Blank HospitalAtlanta, GeorgiaRecruiting
Children's Hospital and Medical Center of OmahaOmaha, NebraskaRecruiting
Children's Hospital ColoradoAurora, ColoradoRecruiting
Children's Hospital Los AngelesLos Angeles, CaliforniaRecruiting
Children's Hospital Medical Center of AkronAkron, OhioRecruiting
Children's Hospital New OrleansNew Orleans, LouisianaRecruiting
Children's Hospital of AlabamaBirmingham, AlabamaRecruiting
Children's Hospital of MichiganDetroit, MichiganRecruiting
Children's Hospital of Orange CountyOrange, CaliforniaRecruiting
Children's Hospital of PhiladelphiaPhiladelphia, PennsylvaniaRecruiting
Children's Hospital of Pittsburgh of UPMCPittsburgh, PennsylvaniaRecruiting
Children's Hospital of San AntonioSan Antonio, TexasRecruiting
Children's Hospital of The King's DaughtersNorfolk, VirginiaRecruiting
Children's Hospital of WisconsinMilwaukee, WisconsinRecruiting
Children's Hospitals and Clinics of Minnesota - MinneapolisMinneapolis, MinnesotaRecruiting
Children's Mercy Hospitals and ClinicsKansas City, MissouriRecruiting
Children's National Medical CenterWashington D.C., District of ColumbiaRecruiting
Cincinnati Children's Hospital Medical CenterCincinnati, OhioRecruiting
City of Hope Antelope ValleyLancaster, CaliforniaRecruiting
City of Hope at Irvine LennarIrvine, CaliforniaRecruiting
City of Hope at Long Beach ElmLong Beach, CaliforniaRecruiting
City of Hope Comprehensive Cancer CenterDuarte, CaliforniaRecruiting
City of Hope CoronaCorona, CaliforniaRecruiting
City of Hope Newport BeachNewport Beach, CaliforniaRecruiting
City of Hope SeacliffHuntington Beach, CaliforniaRecruiting
City of Hope South BayTorrance, CaliforniaRecruiting
City of Hope South PasadenaSouth Pasadena, CaliforniaRecruiting
City of Hope UplandUpland, CaliforniaRecruiting
Cleveland Clinic FoundationCleveland, OhioRecruiting
Community Medical CenterToms River, New JerseyRecruiting
Condell Memorial HospitalLibertyville, IllinoisRecruiting
Connecticut Children's Medical CenterHartford, ConnecticutRecruiting
Cook Children's Medical CenterFort Worth, TexasRecruiting
Cooper Hospital University Medical CenterCamden, New JerseyRecruiting
Corewell Health Beaumont Troy HospitalTroy, MichiganRecruiting
Corewell Health Children'sRoyal Oak, MichiganRecruiting
Corewell Health Dearborn HospitalDearborn, MichiganRecruiting
Corewell Health Farmington Hills HospitalFarmington Hills, MichiganRecruiting
Corewell Health Grand Rapids Hospitals - Butterworth HospitalGrand Rapids, MichiganRecruiting
Corewell Health Grand Rapids Hospitals - Helen DeVos Children's HospitalGrand Rapids, MichiganRecruiting
Corewell Health Lakeland Hospitals - Marie Yeager Cancer CenterSaint Joseph, MichiganRecruiting
Corewell Health Reed City HospitalReed City, MichiganRecruiting
Corewell Health William Beaumont University HospitalRoyal Oak, MichiganRecruiting
Covenant Children's HospitalLubbock, TexasRecruiting
Crossroads Cancer CenterEffingham, IllinoisRecruiting
CTCA at Western Regional Medical CenterGoodyear, ArizonaRecruiting
Dana-Farber Cancer InstituteBoston, MassachusettsRecruiting
Dartmouth Hitchcock Medical Center/Dartmouth Cancer CenterLebanon, New HampshireRecruiting
Dayton Children's HospitalDayton, OhioRecruiting
Decatur Memorial HospitalDecatur, IllinoisRecruiting
Dell Children's Medical Center of Central TexasAustin, TexasRecruiting
Driscoll Children's HospitalCorpus Christi, TexasRecruiting
Duke University Medical CenterDurham, North CarolinaRecruiting
East Carolina UniversityGreenville, North CarolinaRecruiting
East Tennessee Childrens HospitalKnoxville, TennesseeRecruiting
Eastern Maine Medical CenterBangor, MaineRecruiting
Edward Hospital/Cancer CenterNaperville, IllinoisRecruiting
Edward Hospital/Cancer Center?PlainfieldPlainfield, IllinoisRecruiting
Edwards Comprehensive Cancer CenterHuntington, West VirginiaRecruiting
El Paso Children's HospitalEl Paso, TexasRecruiting
Elmhurst Memorial HospitalElmhurst, IllinoisRecruiting
Emory Proton Therapy CenterAtlanta, GeorgiaRecruiting
Emory Saint Joseph's HospitalAtlanta, GeorgiaRecruiting
Emory University Hospital MidtownAtlanta, GeorgiaRecruiting
Emory University Hospital/Winship Cancer InstituteAtlanta, GeorgiaRecruiting
Fairview Southdale HospitalEdina, MinnesotaRecruiting
Geisinger Medical CenterDanville, PennsylvaniaRecruiting
Glens Falls HospitalGlens Falls, New YorkRecruiting
Golisano Children's Hospital of Southwest FloridaFort Myers, FloridaRecruiting
Grady Health SystemAtlanta, GeorgiaRecruiting
Gundersen Lutheran Medical CenterLa Crosse, WisconsinRecruiting
Hackensack University Medical CenterHackensack, New JerseyRecruiting
Hematology Oncology Associates of Central New York-East SyracuseEast Syracuse, New YorkRecruiting
Hematology Oncology Associates of CNY at CamillusCamillus, New YorkRecruiting
Henry Ford Cancer Institute-DownriverBrownstown, MichiganRecruiting
Henry Ford Health Providence Novi HospitalNovi, MichiganRecruiting
Henry Ford Health Providence Southfield HospitalSouthfield, MichiganRecruiting
Henry Ford HospitalDetroit, MichiganRecruiting
Henry Ford Macomb Hospital-Clinton TownshipClinton Township, MichiganRecruiting
Henry Ford Medical Center-ColumbusNovi, MichiganRecruiting
Henry Ford Medical Center-FairlaneDearborn, MichiganRecruiting
Henry Ford West Bloomfield HospitalWest Bloomfield, MichiganRecruiting
Henry Ford Wyandotte HospitalWyandotte, MichiganRecruiting
HSHS Saint Elizabeth's HospitalO'Fallon, IllinoisRecruiting
Hunterdon Medical CenterFlemington, New JerseyRecruiting
Huntsman Cancer Institute/University of UtahSalt Lake City, UtahRecruiting
Inova Fairfax HospitalFalls Church, VirginiaRecruiting
Iowa Methodist Medical CenterDes Moines, IowaRecruiting
Jersey City Medical CenterJersey City, New JerseyRecruiting
Johns Hopkins All Children's HospitalSt. Petersburg, FloridaRecruiting
Johns Hopkins University/Sidney Kimmel Cancer CenterBaltimore, MarylandRecruiting
Kaiser Permanente Downey Medical CenterDowney, CaliforniaRecruiting
Kaiser Permanente Downtown CommonsSacramento, CaliforniaRecruiting
Kaiser Permanente DublinDublin, CaliforniaRecruiting
Kaiser Permanente San LeandroSan Leandro, CaliforniaRecruiting
Kaiser Permanente-FremontFremont, CaliforniaRecruiting
Kaiser Permanente-FresnoFresno, CaliforniaRecruiting
Kaiser Permanente-ModestoModesto, CaliforniaRecruiting
Kaiser Permanente-OaklandOakland, CaliforniaRecruiting
Kaiser Permanente-San FranciscoSan Francisco, CaliforniaRecruiting
Kaiser Permanente-Santa RosaSanta Rosa, CaliforniaRecruiting
Kaiser Permanente-Santa Teresa-San JoseSan Jose, CaliforniaRecruiting
Kaiser Permanente-South SacramentoSacramento, CaliforniaRecruiting
Kaiser Permanente-South San FranciscoSouth San Francisco, CaliforniaRecruiting
Kaiser Permanente-VallejoVallejo, CaliforniaRecruiting
Kaiser Permanente-Walnut CreekWalnut Creek, CaliforniaRecruiting
Kaiser San Rafael-GallinasSan Rafael, CaliforniaRecruiting
Kapiolani Medical Center for Women and ChildrenHonolulu, HawaiiRecruiting
Laura and Isaac Perlmutter Cancer Center at NYU LangoneNew York, New YorkRecruiting
Legacy Emanuel Children's HospitalPortland, OregonRecruiting
Lehigh Valley Hospital-Cedar CrestAllentown, PennsylvaniaRecruiting
Loma Linda University Medical CenterLoma Linda, CaliforniaRecruiting
Loyola University Medical CenterMaywood, IllinoisRecruiting
Lurie Children's Hospital-ChicagoChicago, IllinoisRecruiting
Maine Children's Cancer ProgramScarborough, MaineRecruiting
MaineHealth Cancer Care and IV Therapy - South PortlandSouth Portland, MaineRecruiting
MaineHealth Cancer Care Center of York CountySanford, MaineRecruiting
MaineHealth Coastal Cancer Treatment CenterBath, MaineRecruiting
MaineHealth Maine Medical Center - PortlandPortland, MaineRecruiting
MaineHealth Maine Medical Center- ScarboroughScarborough, MaineRecruiting
Marshfield Medical Center-MarshfieldMarshfield, WisconsinRecruiting
Mary Bridge Children's Hospital and Health CenterTacoma, WashingtonRecruiting
Mayo Clinic in FloridaJacksonville, FloridaRecruiting
Mayo Clinic in RochesterRochester, MinnesotaRecruiting
Medical Center of the RockiesLoveland, ColoradoRecruiting
Medical City Dallas HospitalDallas, TexasRecruiting
Medical University of South CarolinaCharleston, South CarolinaRecruiting
MedStar Georgetown University HospitalWashington D.C., District of ColumbiaRecruiting
Memorial Health University Medical CenterSavannah, GeorgiaRecruiting
Memorial Hospital EastShiloh, IllinoisRecruiting
Memorial Hospital NorthColorado Springs, ColoradoRecruiting
Memorial Regional Hospital/Joe DiMaggio Children's HospitalHollywood, FloridaRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New YorkRecruiting
Mercy Cancer Center - CarmichaelCarmichael, CaliforniaRecruiting
Mercy Cancer Center - Elk GroveElk Grove, CaliforniaRecruiting
Mercy Cancer Center - RocklinRocklin, CaliforniaRecruiting
Mercy Cancer Center - SacramentoSacramento, CaliforniaRecruiting
Mercy HospitalCoon Rapids, MinnesotaRecruiting
Mercy Hospital Saint LouisSt Louis, MissouriRecruiting
Mercy San Juan Medical CenterCarmichael, CaliforniaRecruiting
Methodist Children's Hospital of South TexasSan Antonio, TexasRecruiting
Miller Children's and Women's Hospital Long BeachLong Beach, CaliforniaRecruiting
Minnesota Oncology Hematology PA-WoodburyWoodbury, MinnesotaRecruiting
Mission HospitalAsheville, North CarolinaRecruiting
Monmouth Medical CenterLong Branch, New JerseyRecruiting
Montefiore Medical Center - Moses CampusThe Bronx, New YorkRecruiting
Morristown Medical CenterMorristown, New JerseyRecruiting
Mount Sinai HospitalNew York, New YorkRecruiting
Mount Sinai Hospital Medical CenterChicago, IllinoisRecruiting
Mount Sinai Medical CenterMiami Beach, FloridaRecruiting
Munson Medical CenterTraverse City, MichiganRecruiting
Natalie Warren Bryant Cancer Center at Saint FrancisTulsa, OklahomaRecruiting
Nationwide Children's HospitalColumbus, OhioRecruiting
Naval Medical Center - PortsmouthPortsmouth, VirginiaRecruiting
Naval Medical Center -San DiegoSan Diego, CaliforniaRecruiting
Nebraska Medicine-BellevueBellevue, NebraskaRecruiting
Nebraska Medicine-Village PointeOmaha, NebraskaRecruiting
Nemours Children's Clinic - PensacolaPensacola, FloridaRecruiting
Nemours Children's Clinic-JacksonvilleJacksonville, FloridaRecruiting
Nemours Children's HospitalOrlando, FloridaRecruiting
Newark Beth Israel Medical CenterNewark, New JerseyRecruiting
Nicklaus Children's HospitalMiami, FloridaRecruiting
NorthShore University HealthSystem-Evanston HospitalEvanston, IllinoisRecruiting
NorthShore University HealthSystem-Glenbrook HospitalGlenview, IllinoisRecruiting
NorthShore University HealthSystem-Highland Park HospitalHighland Park, IllinoisRecruiting
Northwestern Medicine Cancer Center DelnorGeneva, IllinoisRecruiting
Northwestern Medicine Cancer Center KishwaukeeDeKalb, IllinoisRecruiting
Northwestern Medicine Cancer Center WarrenvilleWarrenville, IllinoisRecruiting
Northwestern Medicine Orland ParkOrland Park, IllinoisRecruiting
Northwestern UniversityChicago, IllinoisRecruiting
Norton Children's HospitalLouisville, KentuckyRecruiting
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer CenterNew York, New YorkRecruiting
NYP/Weill Cornell Medical CenterNew York, New YorkRecruiting
NYU Langone Hospital - Long IslandMineola, New YorkRecruiting
Ochsner Medical Center JeffersonNew Orleans, LouisianaRecruiting
Oregon Health and Science UniversityPortland, OregonRecruiting
OSF Children's Hospital of IllinoisPeoria, IllinoisRecruiting
Park Nicollet Clinic - Saint Louis ParkSaint Louis Park, MinnesotaRecruiting
Penn State Children's HospitalHershey, PennsylvaniaRecruiting
Phoenix Childrens HospitalPhoenix, ArizonaRecruiting
Poudre Valley HospitalFort Collins, ColoradoRecruiting
Presbyterian HospitalAlbuquerque, New MexicoRecruiting
Primary Children's HospitalSalt Lake City, UtahRecruiting
Prisma Health Cancer Institute - EastsideGreenville, South CarolinaRecruiting
Prisma Health Cancer Institute - SpartanburgBoiling Springs, South CarolinaRecruiting
Prisma Health Richland HospitalColumbia, South CarolinaRecruiting
ProHealth D N Greenwald CenterMukwonago, WisconsinRecruiting
ProHealth Oconomowoc Memorial HospitalOconomowoc, WisconsinRecruiting
ProMedica Toledo Hospital/Russell J Ebeid Children's HospitalToledo, OhioRecruiting
Providence Alaska Medical CenterAnchorage, AlaskaRecruiting
Providence Newberg Medical CenterNewberg, OregonRecruiting
Providence Portland Medical CenterPortland, OregonRecruiting
Providence Sacred Heart Medical Center and Children's HospitalSpokane, WashingtonRecruiting
Providence Saint Vincent Medical CenterPortland, OregonRecruiting
Providence Willamette Falls Medical CenterOregon City, OregonRecruiting
Rady Children's Hospital - San DiegoSan Diego, CaliforniaRecruiting
Rainbow Babies and Childrens HospitalCleveland, OhioRecruiting
Regions HospitalSaint Paul, MinnesotaRecruiting
Renown Regional Medical CenterReno, NevadaRecruiting
Rhode Island HospitalProvidence, Rhode IslandRecruiting
Riley Hospital for ChildrenIndianapolis, IndianaRecruiting
Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical CenterDenver, ColoradoRecruiting
Roswell Park Cancer InstituteBuffalo, New YorkRecruiting
Rush-Copley Healthcare CenterYorkville, IllinoisRecruiting
Rush-Copley Medical CenterAurora, IllinoisRecruiting
Rutgers Cancer Institute of New JerseyNew Brunswick, New JerseyRecruiting
Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University HospitalNew Brunswick, New JerseyRecruiting
Saint Alphonsus Cancer Care Center-NampaNampa, IdahoRecruiting
Saint Barnabas Medical CenterLivingston, New JerseyRecruiting
Saint Christopher's Hospital for ChildrenPhiladelphia, PennsylvaniaRecruiting
Saint Francis Cancer CenterGreenville, South CarolinaRecruiting
Saint Francis HospitalGreenville, South CarolinaRecruiting
Saint Francis Medical CenterCape Girardeau, MissouriRecruiting
Saint Joseph's Hospital/Children's Hospital-TampaTampa, FloridaRecruiting
Saint Joseph's Regional Medical CenterPaterson, New JerseyRecruiting
Saint Luke's Cancer Institute - BoiseBoise, IdahoRecruiting
Saint Luke's Cancer Institute - FruitlandFruitland, IdahoRecruiting
Saint Luke's Cancer Institute - MeridianMeridian, IdahoRecruiting
Saint Luke's Cancer Institute - NampaNampa, IdahoRecruiting
Saint Luke's Cancer Institute - Twin FallsTwin Falls, IdahoRecruiting
Saint Luke's HospitalChesterfield, MissouriRecruiting
Saint Mary's Medical CenterWest Palm Beach, FloridaRecruiting
Saint Peter's University HospitalNew Brunswick, New JerseyRecruiting
Saint Vincent Hospital Cancer Center at SheboyganSheboygan, WisconsinRecruiting
Saint Vincent Hospital Cancer Center at Sturgeon BaySturgeon Bay, WisconsinRecruiting
Saint Vincent Hospital Cancer Center Green BayGreen Bay, WisconsinRecruiting
Sanford Broadway Medical CenterFargo, North DakotaRecruiting
Sanford USD Medical Center - Sioux FallsSioux Falls, South DakotaRecruiting
Santa Barbara Cottage HospitalSanta Barbara, CaliforniaRecruiting
Scott and White Memorial HospitalTemple, TexasRecruiting
Seattle Children's HospitalSeattle, WashingtonRecruiting
Sinai Hospital of BaltimoreBaltimore, MarylandRecruiting
Siteman Cancer Center at Christian HospitalSt Louis, MissouriRecruiting
Siteman Cancer Center at Saint Peters HospitalCity of Saint Peters, MissouriRecruiting
Siteman Cancer Center at West County HospitalCreve Coeur, MissouriRecruiting
Siteman Cancer Center-South CountySt Louis, MissouriRecruiting
Smilow Cancer Hospital Care Center - GuilfordGuilford, ConnecticutRecruiting
Smilow Cancer Hospital Care Center - WaterfordWaterford, ConnecticutRecruiting
Smilow Cancer Hospital Care Center - WesterlyWesterly, Rhode IslandRecruiting
Smilow Cancer Hospital Care Center at GlastonburyGlastonbury, ConnecticutRecruiting
Smilow Cancer Hospital Care Center at GreenwichGreenwich, ConnecticutRecruiting
Smilow Cancer Hospital Care Center at Long RidgeStamford, ConnecticutRecruiting
Smilow Cancer Hospital Care Center at Saint FrancisHartford, ConnecticutRecruiting
Smilow Cancer Hospital Care Center-FairfieldFairfield, ConnecticutRecruiting
Smilow Cancer Hospital Care Center-TrumbullTrumbull, ConnecticutRecruiting
Smilow Cancer Hospital-Derby Care CenterDerby, ConnecticutRecruiting
Smilow Cancer Hospital-Torrington Care CenterTorrington, ConnecticutRecruiting
Smilow Cancer Hospital-Waterbury Care CenterWaterbury, ConnecticutRecruiting
Southern Illinois University School of MedicineSpringfield, IllinoisRecruiting
State University of New York Upstate Medical UniversitySyracuse, New YorkRecruiting
Stony Brook University Medical CenterStony Brook, New YorkRecruiting
Swedish Covenant HospitalChicago, IllinoisRecruiting
Tampa General HospitalTampa, FloridaRecruiting
The Children's Hospital at TriStar CentennialNashville, TennesseeRecruiting
The James Graham Brown Cancer Center at University of LouisvilleLouisville, KentuckyRecruiting
The Steven and Alexandra Cohen Children's Medical Center of New YorkNew Hyde Park, New YorkRecruiting
Thomas Jefferson University HospitalPhiladelphia, PennsylvaniaRecruiting
Trinitas Hospital and Comprehensive Cancer Center - Williamson Street CampusElizabeth, New JerseyRecruiting
Trinity Health Grand Rapids HospitalGrand Rapids, MichiganRecruiting
Trinity Health IHA Medical Group Hematology Oncology - BrightonBrighton, MichiganRecruiting
Trinity Health IHA Medical Group Hematology Oncology - CantonCanton, MichiganRecruiting
Trinity Health IHA Medical Group Hematology Oncology - Chelsea HospitalChelsea, MichiganRecruiting
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor CampusYpsilanti, MichiganRecruiting
Trinity Health Muskegon HospitalMuskegon, MichiganRecruiting
Trinity Health Saint Joseph Mercy Hospital Ann ArborAnn Arbor, MichiganRecruiting
Trinity Health Saint Joseph Mercy Oakland HospitalPontiac, MichiganRecruiting
Trinity Health Saint Mary Mercy Livonia HospitalLivonia, MichiganRecruiting
UC Irvine Health Cancer Center-NewportCosta Mesa, CaliforniaRecruiting
UC Irvine Health/Chao Family Comprehensive Cancer CenterOrange, CaliforniaRecruiting
UCHealth Greeley HospitalGreeley, ColoradoRecruiting
UCHealth Memorial Hospital CentralColorado Springs, ColoradoRecruiting
UCHealth University of Colorado HospitalAurora, ColoradoRecruiting
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory CareIrvine, CaliforniaRecruiting
UF Health Cancer Institute - GainesvilleGainesville, FloridaRecruiting
UI Health Care Mission Cancer and Blood - Ankeny ClinicAnkeny, IowaRecruiting
UI Health Care Mission Cancer and Blood - Des Moines ClinicDes Moines, IowaRecruiting
UI Health Care Mission Cancer and Blood - Laurel ClinicDes Moines, IowaRecruiting
UI Health Care Mission Cancer and Blood - Waukee ClinicWaukee, IowaRecruiting
UI Health Care Mission Cancer and Blood - West Des Moines ClinicClive, IowaRecruiting
UMass Memorial Medical Center - University CampusWorcester, MassachusettsRecruiting
UMC Cancer Center / UMC Health SystemLubbock, TexasRecruiting
UNC Lineberger Comprehensive Cancer CenterChapel Hill, North CarolinaRecruiting
United HospitalSaint Paul, MinnesotaRecruiting
University of Chicago Comprehensive Cancer CenterChicago, IllinoisRecruiting
University of IllinoisChicago, IllinoisRecruiting
University of Iowa/Holden Comprehensive Cancer CenterIowa City, IowaRecruiting
University of Kentucky/Markey Cancer CenterLexington, KentuckyRecruiting
University of Maryland/Greenebaum Cancer CenterBaltimore, MarylandRecruiting
University of Miami Miller School of Medicine-Sylvester Cancer CenterMiami, FloridaRecruiting
University of Michigan Health - WestWyoming, MichiganRecruiting
University of Minnesota/Masonic Cancer CenterMinneapolis, MinnesotaRecruiting
University of Mississippi Medical CenterJackson, MississippiRecruiting
University of Missouri Children's HospitalColumbia, MissouriRecruiting
University of Nebraska Medical CenterOmaha, NebraskaRecruiting
University of Oklahoma Health Sciences CenterOklahoma City, OklahomaRecruiting
University of RochesterRochester, New YorkRecruiting
University of Texas Health Science Center at San AntonioSan Antonio, TexasRecruiting
University of Vermont and State Agricultural CollegeBurlington, VermontRecruiting
University of Virginia Cancer CenterCharlottesville, VirginiaRecruiting
University of Wisconsin Carbone Cancer Center - Eastpark Medical CenterMadison, WisconsinRecruiting
University of Wisconsin Carbone Cancer Center - University HospitalMadison, WisconsinRecruiting
UofL Health Medical Center NortheastLouisville, KentuckyRecruiting
USA Health Strada Patient Care CenterMobile, AlabamaRecruiting
UT MD Anderson Cancer CenterHouston, TexasRecruiting
UT Southwestern/Simmons Cancer Center-DallasDallas, TexasRecruiting
UW Cancer Center at ProHealth CareWaukesha, WisconsinRecruiting
UW Health Carbone Cancer Center RockfordRockford, IllinoisRecruiting
Valley Medical CenterRenton, WashingtonRecruiting
Vanderbilt University/Ingram Cancer CenterNashville, TennesseeRecruiting
VCU Massey Comprehensive Cancer CenterRichmond, VirginiaRecruiting
Vince Lombardi Cancer Clinic - OshkoshOshkosh, WisconsinRecruiting
Vince Lombardi Cancer Clinic-SheboyganSheboygan, WisconsinRecruiting
Vince Lombardi Cancer Clinic-Two RiversTwo Rivers, WisconsinRecruiting
Wake Forest University Health SciencesWinston-Salem, North CarolinaRecruiting
Walter Reed National Military Medical CenterBethesda, MarylandRecruiting
Washington University School of MedicineSt Louis, MissouriRecruiting
Wayne State University/Karmanos Cancer InstituteDetroit, MichiganRecruiting
Weisberg Cancer Treatment CenterFarmington Hills, MichiganRecruiting
Wesley Medical CenterWichita, KansasRecruiting
West Michigan Cancer CenterKalamazoo, MichiganRecruiting
West Virginia University Charleston DivisionCharleston, West VirginiaRecruiting
Wilmot Cancer Institute at WebsterWebster, New YorkRecruiting
Woodland Memorial HospitalWoodland, CaliforniaRecruiting
Yale UniversityNew Haven, ConnecticutRecruiting
Yale-New Haven Hospital North Haven Medical CenterNorth Haven, ConnecticutRecruiting
Jersey Shore Medical CenterNeptune City, New JerseySuspended
Kaiser Permanente Fresno Orchard PlazaFresno, CaliforniaSuspended
Kaiser Permanente- Modesto MOB IIModesto, CaliforniaSuspended
Michigan State UniversityEast Lansing, MichiganActive Not Recruiting
Northwestern Medicine Glenview Outpatient CenterGlenview, IllinoisActive Not Recruiting
Northwestern Medicine Grayslake Outpatient CenterGrayslake, IllinoisActive Not Recruiting
Northwestern Medicine Lake Forest HospitalLake Forest, IllinoisActive Not Recruiting
Sacred Heart HospitalPensacola, FloridaSuspended
T C Thompson Children's HospitalChattanooga, TennesseeSuspended
University of New Mexico Cancer CenterAlbuquerque, New MexicoSuspended

Canada14 locations · 14 recruiting

Alberta Children's HospitalCalgary, AlbertaRecruiting
British Columbia Children's HospitalVancouver, British ColumbiaRecruiting
CancerCare ManitobaWinnipeg, ManitobaRecruiting
Centre Hospitalier Universitaire de Sherbrooke-FleurimontSherbrooke, QuebecRecruiting
Centre Hospitalier Universitaire Sainte-JustineMontreal, QuebecRecruiting
Children's HospitalLondon, OntarioRecruiting
Children's Hospital of Eastern OntarioOttawa, OntarioRecruiting
CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL)QuébecRecruiting
Hospital for Sick ChildrenToronto, OntarioRecruiting
IWK Health CentreHalifax, Nova ScotiaRecruiting
Jim Pattison Children's HospitalSaskatoon, SaskatchewanRecruiting
McMaster Children's Hospital at Hamilton Health SciencesHamilton, OntarioRecruiting
The Montreal Children's Hospital of the MUHCMontreal, QuebecRecruiting
University of Alberta HospitalEdmonton, AlbertaRecruiting

Puerto Rico1 location · 1 recruiting

University Pediatric HospitalSan JuanRecruiting

Who to ask about joining

Site Public Contact205-638-9285 oncologyresearch@peds.uab.edu

Site Public Contact800-388-8721

Site Public Contact907-212-6871 AKPAMC.OncologyResearchSupport@providence.org

Who can join

People aged 5 to 60 years with newly diagnosed classic Hodgkin lymphoma can join the study. They should have measurable cancer and meet certain health criteria, like kidney and liver function. The trial is open to both men and women. The trial team will confirm eligibility before anyone joins.

What happens during the trial

Participants will be placed into different groups by chance. Some will receive standard chemotherapy, while others will get the chemotherapy plus the two drugs. All patients will receive treatment over several cycles, followed by tests to check their response to the treatment. This will help determine the best approach for their care.

The trial team

The trial is sponsored by the National Cancer Institute (NCI), with Kara M Kelly from Roswell Park Cancer Institute as the principal investigator.

Important dates

The trial started on May 11, 2023, and is expected to finish by April 28, 2031. It is currently enrolling new participants.

Additional information

This is a Phase 3 trial, which means it is looking at how well the treatment works and how safe it is. The trial hopes to include about 1,875 participants. It is regulated by the FDA.

Similar trials

Other recruiting trials for the same condition, with the eligibility rules written in plain language.

Browse similar trials →

Talk to a specialist

Find a top oncologist who can tell you whether a trial is a sensible option for you.

Find a doctor →

Cancer hospitals

The cancer centers running studies like this one, and what each is known for.

Browse hospitals →